BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.3645.p (453 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2571 [T] COG0642 Signal transduction histidine kinase Pae Pseu... 294 3e-79 VC1084 [T] COG0642 Signal transduction histidine kinase Vch Vibr... 265 2e-70 VCA0719 [T] COG0642 Signal transduction histidine kinase Vch Vib... 248 2e-65 alr2739 [T] COG0642 Signal transduction histidine kinase Nos Nos... 240 6e-63 alr0642 [T] COG0642 Signal transduction histidine kinase Nos Nos... 238 3e-62 >PA2571 [T] COG0642 Signal transduction histidine kinase Pae Pseudomonas aeruginosa Length = 470 Score = 294 bits (753), Expect = 3e-79, Method: Compositional matrix adjust. Identities = 149/287 (51%), Positives = 206/287 (71%), Gaps = 10/287 (3%) Query: 151 QLEDALQCQAEEQRALIEQLKMAQAQLLQSEKLASIGQLAAGVAHEINNPIGFVNANLNT 210 Q ++AL+ + E++ L ++QL+Q+EKLASIG LAAGVAHEINNPI +V++N T Sbjct: 181 QAKEALEKEIGERKEL-------ESQLVQTEKLASIGHLAAGVAHEINNPISYVSSNYTT 233 Query: 211 LGNYVATLLEGIKLYQCVAGGKLPSSVAQSELQSFEDRADLQFLSEDVTELLSESNEGLQ 270 L +V LLE ++ Y+ ++A+ L+ +R +L F+ EDV LL ES EG+ Sbjct: 234 LEEHVRRLLEVLEAYEEARPAIRDEALAR-RLEQLGERVELAFVKEDVAVLLRESREGIG 292 Query: 271 RVKNIVQSLKDFSRT-GESNWQMADLHRGLDSTLNIANNELKYKVNIVKQYGELPMVKCL 329 RV+ IVQ LK+FSR E +WQ DLH+G++STLNI +ELKY+ ++V++YG+LP VKCL Sbjct: 293 RVRKIVQDLKNFSRVDAEDDWQWTDLHQGIESTLNIVASELKYRADVVREYGDLPEVKCL 352 Query: 330 ASELNQVFMNLLVNAAQAIS-ERGSVTIRTERHGDRVAVSISDTGHGIAPEHINRIFEPF 388 S++NQV MNL++NAAQA+ ERG + IRT + + + D+G GI+PE + RIF+PF Sbjct: 353 PSQINQVVMNLVMNAAQAMGPERGRIVIRTGHTVEHAWIEVEDSGQGISPEILPRIFDPF 412 Query: 389 FTTKPVGSGTGLGLSLSYGIIKKHGGDIHVCSEPGQGTTFRIELPID 435 FTTKPVG GTGLGLSLSYGI++KHGG I V S+PG G+ FRI LP++ Sbjct: 413 FTTKPVGKGTGLGLSLSYGIVQKHGGTIEVRSQPGVGSAFRIVLPLE 459 >VC1084 [T] COG0642 Signal transduction histidine kinase Vch Vibrio cholerae Length = 439 Score = 265 bits (677), Expect = 2e-70, Method: Compositional matrix adjust. Identities = 139/292 (47%), Positives = 195/292 (66%), Gaps = 5/292 (1%) Query: 150 KQLEDALQCQAEEQRALIEQLKMAQAQLLQSEKLASIGQLAAGVAHEINNPIGFVNANLN 209 K++ L+ + + Q+ LI++L+ AQ QL+QSEK+ASIGQL+AG+AHEINNP+GF+ +NL Sbjct: 139 KRVSQKLEEEHQSQKVLIKKLEDAQGQLIQSEKMASIGQLSAGIAHEINNPVGFITSNLQ 198 Query: 210 TLGNYVATLLEGIK-LYQCVAGGKLPSSVAQSELQSFEDRADLQFLSEDVTELLSESNEG 268 TL +Y +L + +K + Q + G+ + Q + + F+ ED EL++ES EG Sbjct: 199 TLSDYFNSLEKVLKSITQTI--GQSKDTALNEACQKILKQGQVDFILEDTAELITESLEG 256 Query: 269 LQRVKNIVQSLKDFSRTGESNWQMADLHRGLDSTLNIANNELKYKVNIVKQYG-ELPMVK 327 RV +IV++LK+FS S W A+L ++STL I NNE+KY + + K Y +P V Sbjct: 257 SSRVMSIVKNLKEFSHVDRSEWSYANLENCIESTLKIINNEIKYNITLEKHYAANVPDVF 316 Query: 328 CLASELNQVFMNLLVNAAQAISERGSVTIRTERHGDR-VAVSISDTGHGIAPEHINRIFE 386 C ++NQV +N+LVNA+ AI G++TI + GD V + I DTG GI E RIFE Sbjct: 317 CQPMQINQVLLNILVNASHAIKGEGTITITLQSAGDDFVEIHIRDTGCGIPEEIRERIFE 376 Query: 387 PFFTTKPVGSGTGLGLSLSYGIIKKHGGDIHVCSEPGQGTTFRIELPIDPAS 438 PFFTTKPVGSGTGLGLS+SYGII KH G I V SE G+G+ F I LP++P++ Sbjct: 377 PFFTTKPVGSGTGLGLSVSYGIINKHNGTISVTSEVGKGSEFTIRLPVNPSA 428 >VCA0719 [T] COG0642 Signal transduction histidine kinase Vch Vibrio cholerae Length = 315 Score = 248 bits (633), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 138/296 (46%), Positives = 190/296 (64%), Gaps = 9/296 (3%) Query: 146 ITGRKQLED---ALQCQAEEQRALIEQLKMAQAQLLQSEKLASIGQLAAGVAHEINNPIG 202 I K LE+ AL + E ++ +EQL AQAQLLQSEK+AS+GQLAAGVAHEINNPIG Sbjct: 19 ILAEKLLEEKSRALYDKVLELQSTLEQLNGAQAQLLQSEKMASVGQLAAGVAHEINNPIG 78 Query: 203 FVNANLNTLGNYVATLLEGIKLYQCVAGGKLPSSVAQSELQSFEDRADLQFLSEDVTELL 262 F +NLNTL +Y + + A S Q+ ++ F+ + DL F+ EDV L+ Sbjct: 79 FCLSNLNTLRDYAEVFAQLADFVEQSAPSFEGSEFYQAWMR-FKQQHDLAFVREDVLSLV 137 Query: 263 SESNEGLQRVKNIVQSLKDFSRTGESNWQMADLHRGLDSTLNIANNELKYKVNIVKQYGE 322 ES GL RVK+IV SL+ S + + + +L+ ++S L I N+ KY + + +Q E Sbjct: 138 EESASGLHRVKDIVTSLQSVSHSSDGRFAECNLNDCIESALRIVWNQFKYTMLVDRQLAE 197 Query: 323 -LPMVKCLASELNQVFMNLLVNAAQAISERGSVTIRTERHGDR----VAVSISDTGHGIA 377 LP +K +A E+ QV MN+ +NA+ A E G +TI T+ ++ V V I+D GHGI+ Sbjct: 198 NLPKIKGIAPEIQQVLMNMFINASHACDEHGELTITTDTLNEKGKAWVQVQIADNGHGIS 257 Query: 378 PEHINRIFEPFFTTKPVGSGTGLGLSLSYGIIKKHGGDIHVCSEPGQGTTFRIELP 433 PEH+ +IF+PFFTTKPVG GTGLGLS+++GI++KH G I V SE GQGT F + P Sbjct: 258 PEHLAKIFDPFFTTKPVGVGTGLGLSIAFGIVEKHQGKISVTSEVGQGTRFTLLFP 313 >alr2739 [T] COG0642 Signal transduction histidine kinase Nos Nostoc sp. PCC 7120 Length = 591 Score = 240 bits (612), Expect = 6e-63, Method: Compositional matrix adjust. Identities = 139/331 (41%), Positives = 202/331 (61%), Gaps = 37/331 (11%) Query: 143 MTDITGRKQLEDALQCQAE-EQRALIEQLKMAQAQLLQSEKLASIGQLAAGVAHEINNPI 201 +T++ R +LE A + QAE E + +++L+ QAQL+Q+EK++S+GQL AGVAHEINNP+ Sbjct: 258 LTNMNQRLELEIAERKQAELELQKALQELQQTQAQLIQTEKMSSLGQLVAGVAHEINNPV 317 Query: 202 GFVNANLNTLGNYVATLLEGIKLYQCVAGGKLPSSVAQSELQSFEDRADLQFLSEDVTEL 261 F+ N+ Y LLE I LYQ PS+V Q ++ DL+FL ED+ ++ Sbjct: 318 SFIYGNITHAKEYTEKLLELIHLYQQELTE--PSAVIQEKIAEI----DLEFLQEDLPKI 371 Query: 262 LSESNEGLQRVKNIVQSLKDFSRTGESNWQMADLHRGLDSTLNIANNELK-----YKVNI 316 LS G QR++ IV SL++FSR E+ + D+H G++STL I N K Y + I Sbjct: 372 LSSMKMGSQRIQQIVLSLRNFSRLDEAEMKEVDIHEGIESTLLILQNRFKAKSQSYNIEI 431 Query: 317 VKQYGELPMVKCLASELNQVFMNLLVNAAQAI------------------SERGS----- 353 +K+YG+LP+V+C A +LNQVFMN++ NA A+ +ER + Sbjct: 432 IKEYGQLPLVECHAGQLNQVFMNIINNAVDALEGSVVSGQWSIVNGKTTNNERLTNNSPQ 491 Query: 354 VTIRTE-RHGDRVAVSISDTGHGIAPEHINRIFEPFFTTKPVGSGTGLGLSLSYGI-IKK 411 ++IRTE + +RV + I+D G GI + ++F+PFFTTKPVG GTGLGLS+SY I + K Sbjct: 492 ISIRTEINNNNRVVIRIADNGPGINQLVMQKLFDPFFTTKPVGQGTGLGLSISYQIVVDK 551 Query: 412 HGGDIHVCSEPGQGTTFRIELPIDPASVQTP 442 H G + SE G+GT F IE+P+ + P Sbjct: 552 HSGVLRCESEIGKGTEFWIEIPLRQVQPEKP 582 >alr0642 [T] COG0642 Signal transduction histidine kinase Nos Nostoc sp. PCC 7120 Length = 735 Score = 238 bits (606), Expect = 3e-62, Method: Compositional matrix adjust. Identities = 127/308 (41%), Positives = 191/308 (62%), Gaps = 26/308 (8%) Query: 147 TGRKQLEDALQCQAEEQRALIEQLKMAQAQLLQSEKLASIGQLAAGVAHEINNPIGFVNA 206 T + +LED ++ + + + + +L+ QAQ++Q EK++S+GQL AGVAHEINNP+ F+ Sbjct: 426 TSKAELEDRVEQRTADLKTALTELQRTQAQVIQGEKMSSLGQLVAGVAHEINNPVNFIYG 485 Query: 207 NLNTLGNYVATLLEGIKLYQCVAGGKLPSSVAQSELQSFEDRADLQFLSEDVTELLSESN 266 N+ L Y LL I LYQ + PS E+Q+ DL FL ED+ ++LS N Sbjct: 486 NITHLNAYTQDLLRMIHLYQ----ERHPSD--DPEVQALATEIDLDFLVEDLQKMLSSMN 539 Query: 267 EGLQRVKNIVQSLKDFSRTGESNWQMADLHRGLDSTLNIANNELKYK-----VNIVKQYG 321 G +R+++IV SL++FSR E+ ++ D+H G++STL I + LK + + +++ YG Sbjct: 540 MGTERIRSIVLSLRNFSRIDEAEFKAVDIHEGIESTLLILQHRLKDQPDKPAIEVIRDYG 599 Query: 322 ELPMVKCLASELNQVFMNLLVNAAQAISER-------------GSVTIRTE-RHGDRVAV 367 LP+++C A +LNQV MN+LVNA A+ E +TIRT + + Sbjct: 600 NLPLIECYAGQLNQVLMNILVNAIDALDELNIKRTYEEIKANPSQITIRTSVNDAQWMEI 659 Query: 368 SISDTGHGIAPEHINRIFEPFFTTKPVGSGTGLGLSLSYGII-KKHGGDIHVCSEPGQGT 426 +I+D G GI + NRIF+PFFTTKPVG GTG+G+++SY II +KH G + S GQG+ Sbjct: 660 AIADNGPGIPEQLKNRIFDPFFTTKPVGKGTGMGMAISYQIITEKHSGKLECFSTVGQGS 719 Query: 427 TFRIELPI 434 FRI++PI Sbjct: 720 EFRIQVPI 727