BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.3639.p (747 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value alr2279_3 [T] COG0642 Signal transduction histidine kinase Nos N... 221 4e-57 MA2013_2 [T] COG0642 Signal transduction histidine kinase Mac Me... 213 1e-54 PA1611_1 [T] COG0642 Signal transduction histidine kinase Pae Ps... 213 1e-54 PA0928_1 [T] COG0642 Signal transduction histidine kinase Pae Ps... 209 3e-53 PA3462_2 [T] COG0642 Signal transduction histidine kinase Pae Ps... 207 8e-53 >alr2279_3 [T] COG0642 Signal transduction histidine kinase Nos Nostoc sp. PCC 7120 Length = 260 Score = 221 bits (563), Expect = 4e-57, Method: Compositional matrix adjust. Identities = 114/237 (48%), Positives = 165/237 (69%), Gaps = 3/237 (1%) Query: 340 KEEAVKANQAKSRFLAMVSHEIRTPMNGILGLSELLMESDLTIKQRHYADSIHNASGGLV 399 K+ A KAN AKS FLA +SHEIRTPMN I+G+S LL+++ L +Q Y ++I N+S L+ Sbjct: 2 KQVAEKANMAKSNFLATMSHEIRTPMNAIIGMSGLLLDTTLKPEQFDYVETIRNSSHTLL 61 Query: 400 RIINDILDFSKIESGKLDLEGVAFHPVRLVRELVELYRPSMHNKDVQLDVRIDCEEALCV 459 IINDILDFSKIESGKL+LE F V E ++L P +K ++L +++ + V Sbjct: 62 TIINDILDFSKIESGKLELEEQPFDLRLCVEEALDLLAPQAASKGIELMYQLEPDTPTLV 121 Query: 460 VGDPSRLKQVLGNLLSNAIKFTQAGYVRLSMSAQQ---EQVTPARWRLFFAISDSGIGIT 516 VGD +R++Q+L NL+SNA+KFT+ G + +++ A+Q +Q P R+ FA+ D+GIGI Sbjct: 122 VGDITRIRQILWNLVSNAVKFTKIGEICITIGAKQKIYKQTDPTRYEFQFAVQDTGIGIE 181 Query: 517 PEALTQLFQPFTQADSSISRRFGGTGLGLAISKNLVELMGGSISCQSIPGESTKFSF 573 + L +LF+PF+Q D+S++RR+GGTGLGLAISK L E+MGG + +S + + F F Sbjct: 182 RDRLHRLFKPFSQVDASMTRRYGGTGLGLAISKRLSEIMGGKMWVESQSHQGSIFYF 238 >MA2013_2 [T] COG0642 Signal transduction histidine kinase Mac Methanosarcina acetivorans str.C2A Length = 296 Score = 213 bits (542), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 115/267 (43%), Positives = 160/267 (59%), Gaps = 9/267 (3%) Query: 340 KEEAVKANQAKSRFLAMVSHEIRTPMNGILGLSELLMESDLTIKQRHYADSIHNASGGLV 399 KE A AN+AK FLA +SHEIRTPMN +LG+ E+L+E+ LT +QR Y H ++ L+ Sbjct: 11 KEAAESANKAKGDFLANMSHEIRTPMNAVLGMLEMLLETSLTDEQREYLQLAHASAESLL 70 Query: 400 RIINDILDFSKIESGKLDLEGVAFHPVRLVRELVELYRPSMHNKDVQLDVRIDCEEALCV 459 II+D+LDFSKIE KL+LE ++F L+ ++ L +K ++L I+ + Sbjct: 71 SIIDDVLDFSKIEQNKLELEQISFELESLISHIINLLSGKAGSKGLKLAFHIEKDLPSTF 130 Query: 460 VGDPSRLKQVLGNLLSNAIKFTQAGYVRLSM---------SAQQEQVTPARWRLFFAISD 510 +GDP RLKQVL N+L NAIKFT+ G + LS+ S P L F + D Sbjct: 131 IGDPVRLKQVLFNILGNAIKFTKKGEIALSVEVYMPSERNSGLSNSDFPEEVALLFKVKD 190 Query: 511 SGIGITPEALTQLFQPFTQADSSISRRFGGTGLGLAISKNLVELMGGSISCQSIPGESTK 570 +GIGI PE L+Q+F PF QAD+S++R +GGTGLGLAIS LVELM G I +S G+ Sbjct: 191 TGIGIPPEKLSQIFDPFIQADASVTREYGGTGLGLAISSQLVELMEGRIWVESEVGKGCT 250 Query: 571 FSFDIVCPEGVEPVTAPATHSVPPPAV 597 F F + G +++P ++ Sbjct: 251 FYFTVRVKRGESSENYGQGNNIPEESL 277 >PA1611_1 [T] COG0642 Signal transduction histidine kinase Pae Pseudomonas aeruginosa Length = 516 Score = 213 bits (542), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 115/256 (44%), Positives = 168/256 (65%), Gaps = 3/256 (1%) Query: 324 RQMRRREQDAILAVELKEEAVKANQAKSRFLAMVSHEIRTPMNGILGLSELLMESDLTIK 383 R R +EQ + +EEA +AN+AKS FLAM+SHE+RTPMNG+LG+ +LL ++ T + Sbjct: 240 RASREQEQAIGQLISAREEAEQANRAKSDFLAMMSHELRTPMNGVLGMLQLLETTEQTRE 299 Query: 384 QRHYADSIHNASGGLVRIINDILDFSKIESGKLDLEGVAFHPVRLVRELVELYRPSMHNK 443 Q Y ++ L+++INDILDFS+IE G L+LE + F+ + LV+ +++ S + Sbjct: 300 QAEYTALATESTEHLLKVINDILDFSRIERGALELECIPFNLLELVQGSALVFQHSAQQR 359 Query: 444 DVQLDVRIDCE-EALCVVGDPSRLKQVLGNLLSNAIKFTQAGYVRLSMSAQQEQVTPARW 502 + L+++I E + V GDP+R++Q+L NLL NA+KFT+ G + LS+ Q W Sbjct: 360 GLALELQIQAGLENIEVCGDPTRIRQILVNLLGNALKFTEEGAIHLSLEWQALD-HDVLW 418 Query: 503 RLFFAISDSGIGITPEALTQLFQPFTQADSSISRRFGGTGLGLAISKNLVELMGGSISCQ 562 L A+ DSGIGI+PE L +F F QADSSISRR+GGTGLGLAI++ L E MGG++ + Sbjct: 419 -LTCAVHDSGIGISPERLEHMFDAFQQADSSISRRYGGTGLGLAIARTLAERMGGTLQAE 477 Query: 563 SIPGESTKFSFDIVCP 578 S G + F+ +I P Sbjct: 478 SKEGSGSTFTLEIPLP 493 >PA0928_1 [T] COG0642 Signal transduction histidine kinase Pae Pseudomonas aeruginosa Length = 509 Score = 209 bits (531), Expect = 3e-53, Method: Compositional matrix adjust. Identities = 108/232 (46%), Positives = 160/232 (68%), Gaps = 2/232 (0%) Query: 340 KEEAVKANQAKSRFLAMVSHEIRTPMNGILGLSELLMESDLTIKQRHYADSIHNASGGLV 399 ++EA++A++ KS FLA +SHEIRTP+NGILG + LL +S+L+ +Q+ Y +I ++ L+ Sbjct: 274 RKEALEASRIKSEFLANMSHEIRTPLNGILGFTNLLQKSELSPRQQDYLTTIQKSAESLL 333 Query: 400 RIINDILDFSKIESGKLDLEGVAFHPVRLVRELVELYRPSMHNKDVQLDVRIDCEEALCV 459 IIN+ILDFSKIE+GKL LE + F+ L+++ + + P+ H K ++L + + + + Sbjct: 334 GIINEILDFSKIEAGKLVLENLPFNLRDLIQDALTMLAPAAHEKQLELVSLVYRDTPIQL 393 Query: 460 VGDPSRLKQVLGNLLSNAIKFTQAGYVRLSMSAQQEQVTPARWRLFFAISDSGIGITPEA 519 GDP RLKQ+L NL+ NAIKFTQ G V ++ A E + R +L ++ D+GIG++ E Sbjct: 394 QGDPQRLKQILTNLVGNAIKFTQGGTV--AVRAMLEDESDDRAQLRISVQDTGIGLSEED 451 Query: 520 LTQLFQPFTQADSSISRRFGGTGLGLAISKNLVELMGGSISCQSIPGESTKF 571 LF+ F+QAD+S+SR+ GGTGLGL ISK L+E MGG I S PGE +F Sbjct: 452 QQALFKAFSQADNSLSRQAGGTGLGLVISKRLIEQMGGEIGVDSTPGEGAEF 503 >PA3462_2 [T] COG0642 Signal transduction histidine kinase Pae Pseudomonas aeruginosa Length = 385 Score = 207 bits (527), Expect = 8e-53, Method: Compositional matrix adjust. Identities = 108/227 (47%), Positives = 156/227 (68%), Gaps = 2/227 (0%) Query: 349 AKSRFLAMVSHEIRTPMNGILGLSELLMESDLTIKQRHYADSIHNASGGLVRIINDILDF 408 AKSRFLA +SHEIRTP+NG+LG+ +LL ++ L Q Y ++I ++ L+ +INDILD+ Sbjct: 1 AKSRFLAKMSHEIRTPLNGVLGMLQLLRDTPLDRGQAAYVETIASSGSALMSVINDILDY 60 Query: 409 SKIESGKLDLEGVAFHPVRLVRELVELYRPSMHNKDVQLDVRIDCEEALCVVGDPSRLKQ 468 ++IESGKL LE + F L+ + + L+ K + L + +D + GDP+RL+Q Sbjct: 61 ARIESGKLHLERIDFDLEELLSDTLALFSAQAVEKRLHLHLGLDRGVPRRLNGDPTRLRQ 120 Query: 469 VLGNLLSNAIKFTQAGYVRLSMSAQQEQVTPARWRLFFAISDSGIGITPEALTQLFQPFT 528 VL NLLSNA+KFT G+V ++ Q+ R RL +++SDSGIGI+ +A LF+ F+ Sbjct: 121 VLMNLLSNALKFTAEGHV--AVRVQRRFDEGGRERLLYSVSDSGIGISAQAQKTLFESFS 178 Query: 529 QADSSISRRFGGTGLGLAISKNLVELMGGSISCQSIPGESTKFSFDI 575 QADSS +RR+GG+GLGLAIS+ LV++MGG I S PG+ T+FS D+ Sbjct: 179 QADSSTTRRYGGSGLGLAISRELVQMMGGRIEVSSEPGKGTRFSVDL 225