BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.3608.p (1133 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0896 Non COG 478 e-134 PA4735 Non COG 267 9e-71 AGc3717 Non COG 40 0.027 PA2708 Non COG 38 0.16 SPBC577.06c [TDBLU] COG5032 Phosphatidylinositol kinase and prot... 35 0.71 >RSc0896 Non COG Length = 1261 Score = 478 bits (1231), Expect = e-134, Method: Compositional matrix adjust. Identities = 273/656 (41%), Positives = 395/656 (60%), Gaps = 35/656 (5%) Query: 497 LKLDDSSVQLADLRLTPPGQGAQPLSLSSLALQAPTLSDTLDQAIPFKLQARFDQNGSAE 556 L+LD+ ++ D + P + + + L + S L + + ++ A G + Sbjct: 622 LRLDNGAIGFEDQTNSRPVK----VRVEPLNVLVQNASTDLGKPVDVQIGAGLGSKGKLD 677 Query: 557 LSGQAAPHFKNVELELDIKDLPITPFQHYFSNVLNVTLSSGLASAKGKLAITPPLQERKL 616 + G P EL ++ ++L + F Y LN ++S L + G LA+ Q + L Sbjct: 678 VRGNVVPQPLKAELRVNAQNLSLAGFDPYLDKSLNAAITSALLTMDGHLALN---QGKAL 734 Query: 617 ALDYKGSAAVTNLRMQDKRTGTDFLRWRTLELAGIQARL-GGRPQVSLEKVTLANFYARA 675 ++Y+G+A + N+R+QD+ + DFLRWR+L L IQ G P+V + + L+ FYAR Sbjct: 735 TVNYQGNATLGNVRLQDRVSSDDFLRWRSLALNRIQVSYDGATPRVRVGALALSTFYARI 794 Query: 676 ILSEQGRLNLQDIVVADAQQQGSITDDKKGSKEAPASSA------TNARKTTSTAAVTSA 729 I++ GRLNLQDI V ++ S+T G +PA+++ + +AVT+ Sbjct: 795 IINPNGRLNLQDIRVQPTEEHRSLTQATPGPASSPAATSGNAVAAASVPAANPASAVTAG 854 Query: 730 APTADTPI--------VQVGQVVLQGGNINYTDNFVKPNYTANMTGLAGTIGQIS-SEKP 780 P + +++ + LQ GNI +TDNF+KPNYTAN+T + G++G IS S Sbjct: 855 MPASAMAAAPKAGGADLRIDAITLQDGNIRFTDNFIKPNYTANLTTIGGSVGTISTSAGQ 914 Query: 781 QPAPVNISGKIDNDAPLQISGALNPLFKPMYLDLKASANGVQLPRLTPYSAKYAGYPITK 840 QPA V + G +D AP+ I G +NPL ++DL A AN ++L LTPYSAKYAGYPITK Sbjct: 915 QPADVTLRGSVDGTAPVDIHGKVNPLAPTAFVDLSAKANDIELTNLTPYSAKYAGYPITK 974 Query: 841 GKLSMDVQYKIENDKLVAQNDLRIEQLTFGERVDSPNATNLPVMLAVSLLKDREGNINLN 900 GKL+MD+ Y ++ KL A N + I+QLTFGERV+S +ATNLPV LAV+LLK+ G I++ Sbjct: 975 GKLTMDLHYLLDQGKLSADNHIFIDQLTFGERVESKDATNLPVRLAVALLKNSRGEIDVR 1034 Query: 901 LPISGSLSDPEFSVGGIIVRVFVNLIVKAVTSPFALIGSMF--RADEHIGDLHYIAFAPG 958 +P+SGSL DP+FS+GG+IVR FVNLIV+AVT+PF+L+ + F E +G YI F PG Sbjct: 1035 VPVSGSLDDPQFSLGGVIVRAFVNLIVRAVTAPFSLLANAFGGSGGEELG---YIEFDPG 1091 Query: 959 SSEIDDEVRKKLDALGYALHERPGIKLDITGRVDPQVDDQGLRREALERKMRGLKRADL- 1017 ++ + K+D L AL +RP +KLDI GRVDP VD GLRRE + R++R K D Sbjct: 1092 TAVLSQASMAKIDKLATALKDRPALKLDIIGRVDPAVDRDGLRRETVNRQIREQKLKDAG 1151 Query: 1018 IAKEGQPSGPVRISAAERGKYLERVYKDSTFDKPRNMIGLTKSLPEAEMEKMILEHTDIT 1077 A E + + E KYLER YK + F KPRN+IGL KSLP EM K++ + +T Sbjct: 1152 DATEADST----VKPDEMDKYLERAYKAAKFPKPRNVIGLAKSLPPDEMRKLMETNVQVT 1207 Query: 1078 QDDLRNLAQRRADQVRNYLQEQSIIEPARIFLIAPKLDGAGLPAQEPKARVDLTIQ 1133 DLR LAQRRA+ V L E+ +EPAR+F++APKLD G+ + +RVD +++ Sbjct: 1208 DSDLRELAQRRANAVHVALAER--VEPARLFVVAPKLDPEGIKDKGKTSRVDFSLK 1261 Score = 202 bits (514), Expect = 4e-51, Method: Compositional matrix adjust. Identities = 180/574 (31%), Positives = 272/574 (47%), Gaps = 42/574 (7%) Query: 13 PTWQR-------LRRPLRWLTWTVAVLLTLAA---LSWAALPALVRKIAIDQTQAQIGRK 62 P WQR +R R + VL+ LA L P L+ +A Q + R Sbjct: 29 PGWQRAARLGEQVRASRRTRRIGLGVLIFLAVFGLLGAVGGPPLLHHLAETQLSKYLERP 88 Query: 63 LEIGQISFNPFKLALRASDITLYEADGKRPFFSTQGLLADLSSASLLRLAPVLDEIKLTT 122 + +G+I NP+ L L + + E DGK PF L + + +S+ R APV++E+K+ Sbjct: 89 VTVGKIRLNPYTLRLEIDQLHIAERDGKTPFIDIGHLHVNAAWSSVFRRAPVIEELKVDA 148 Query: 123 PQLHLVRLDADGIGHYNFSDILDRLAA-----QPKSEGQARFSLANVQLQDGAIHFEDKV 177 P++ +VR +NFSDI+D+L +PKS ARF AN+QL +GAI F D+ Sbjct: 149 PRVRIVRTAEQ---RFNFSDIVDKLTQPEVPPKPKSNEPARFVFANLQLNNGAIQFVDQP 205 Query: 178 SGKNIDIAALQVGLPFISNLPGNIDSYVQPQLSAIINGTPLHLKGRSKPFTASQESAFAI 237 G + LQ+G+PF+++LP ++D +VQP L+A I+G PLH G++KPF S ES+ I Sbjct: 206 LGAQHTVDGLQIGVPFLASLPADVDIFVQPLLAARIDGAPLHFAGKTKPFAQSLESSLNI 265 Query: 238 DIDQLDLVSYLPFVPAELPVAIQSAKLSTRLDLGFTR-QDDKPTVTLAGDIRIDDIALQD 296 +D L+L YL +VP LPVA+ KL+T L + F + + P + + G +D + + D Sbjct: 266 KLDGLELPRYLGYVPGPLPVAVPQGKLTTDLTIDFQKPRTGNPVLRVHGTAGLDGLEVTD 325 Query: 297 KTRAPLLKAKSLALQLKQFDLLAASGEVSQLTLEQPQVWASMNARGELNWVRAFASPTKP 356 +APL+ AK L L L + L+L+ +V A G +N+ + Sbjct: 326 TKKAPLVAAKQLRATLSDVRPLDNVYHLDMLSLDGVRVDAVRAPDGSINFAQL------- 378 Query: 357 ASKGASSAPSKATTPAATTPAAAIVLQQLNLHGGEINWRDEANAAPAQTIKLSKVELNAA 416 K A A A PAA + + +L L ++WRD A PA + L + +AA Sbjct: 379 GGKPAPEAKPAAPAPAAQPKPLDVAVGKLQLANSSVHWRD-ATTQPAADLVLDDLHGDAA 437 Query: 417 QLSTAADAQPARLTLSAVENGHGKLGFDGQLQPLKPTLAGKITLDGVDLAGYQNYLARAP 476 + P L + A G L G K T ++ L+ + LAG YL +A Sbjct: 438 VRTLGG---PTTLDVGAKLASGGTLNVKGSTSLEKRTGELELKLEALKLAGIGPYLRQAG 494 Query: 477 ITDL-SGKLSGKTTLQLREGHLKLDDSS----VQLADLRLTPPGQGAQPL-------SLS 524 L +G LS + L G K + + LADL L P + L + Sbjct: 495 APQLQNGALSADGKIALEFGADKFNVHAEPLVATLADLALAPATRNDTALRAKQLRADIK 554 Query: 525 SLALQAPTLSDTLDQAIPFKLQARFDQNGSAELS 558 S L A TL+ +A +L Q+GS L+ Sbjct: 555 SFDLAARTLALNEVRADGLQLDVLRKQDGSTVLT 588 Score = 67.4 bits (163), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 117/491 (23%), Positives = 192/491 (39%), Gaps = 59/491 (12%) Query: 63 LEIGQISFNPFKLALRAS--DITLYEADGKRPFFSTQGLLADLSSASLLRLAPVLDEIKL 120 LE G FN L A+ D+ L A + L AD+ S L L+E++ Sbjct: 511 LEFGADKFNVHAEPLVATLADLALAPATRNDTALRAKQLRADIKSFDLAARTLALNEVRA 570 Query: 121 TTPQLHLVRLDADGIGHYNFSDILDRLAAQ----PKSEGQAR-----FSLANVQLQDGAI 171 QL ++R DG D + AA+ P + G ++ ++L +GAI Sbjct: 571 DGLQLDVLR-KQDGSTVLTLLDTAQQAAAKAKAAPTTSGAPAEKPWAVTVQALRLDNGAI 629 Query: 172 HFEDKVSGKNIDIAALQVGLPFISNLPGNIDSYVQPQLSAIINGTPLHLKGRSKPFTASQ 231 FED+ + + + + + + + N ++ V Q+ A + G+ L R Sbjct: 630 GFEDQTNSRPVKVRVEPLNV-LVQNASTDLGKPVDVQIGAGL-GSKGKLDVRGNVVPQPL 687 Query: 232 ESAFAIDIDQLDLVSYLPFVPAELPVAIQSAKLSTRLDLGFTRQDDKPTVTLAGDIRIDD 291 ++ ++ L L + P++ L AI SA L+ L Q TV G+ + + Sbjct: 688 KAELRVNAQNLSLAGFDPYLDKSLNAAITSALLTMDGHLALN-QGKALTVNYQGNATLGN 746 Query: 292 IALQDKTRAP-LLKAKSLALQLKQFDLLAASGEVSQLTLEQPQVWASM--NARGELNWVR 348 + LQD+ + L+ +SLAL Q A+ V L +A + N G LN Sbjct: 747 VRLQDRVSSDDFLRWRSLALNRIQVSYDGATPRVRVGALALSTFYARIIINPNGRLNLQD 806 Query: 349 AFASPTKPASKGASSAPSKATTPAATTP-------------------------------- 376 PT+ + P A++PAAT+ Sbjct: 807 IRVQPTEEHRSLTQATPGPASSPAATSGNAVAAASVPAANPASAVTAGMPASAMAAAPKA 866 Query: 377 -AAAIVLQQLNLHGGEINWRDEANAAPAQTIKLSKVELNAAQLSTAADAQPARLTLSAVE 435 A + + + L G I + D P T L+ + + +ST+A QPA +TL Sbjct: 867 GGADLRIDAITLQDGNIRFTDNF-IKPNYTANLTTIGGSVGTISTSAGQQPADVTLRGSV 925 Query: 436 NGHGKLGFDGQLQPLKPT----LAGKIT-LDGVDLAGYQNYLARAPITDLSGKLSGKTTL 490 +G + G++ PL PT L+ K ++ +L Y A PIT GKL+ Sbjct: 926 DGTAPVDIHGKVNPLAPTAFVDLSAKANDIELTNLTPYSAKYAGYPIT--KGKLTMDLHY 983 Query: 491 QLREGHLKLDD 501 L +G L D+ Sbjct: 984 LLDQGKLSADN 994 >PA4735 Non COG Length = 1088 Score = 267 bits (683), Expect = 9e-71, Method: Compositional matrix adjust. Identities = 205/683 (30%), Positives = 325/683 (47%), Gaps = 84/683 (12%) Query: 473 ARAPITDLSGKLSGKTTLQLREGHLKLDDSSVQLADLRLTPPGQGAQ------------- 519 ++AP T GK +G+ T + E DS QLAD TPP + + Sbjct: 423 SKAPKT---GKATGQETAKTAEIDKAASDSPQQLADTAKTPPPESTKASAETPAKPWNIV 479 Query: 520 ----------------------PLSLSSLALQAPTLSDTLDQAIPFKLQARFDQNGSAEL 557 PL + L L + KL+ G + Sbjct: 480 LRDAQLRGYKAHLVDRQPATEVPLEVGPLDLDLQNVDSLGKTPFDLKLKTGLGNRGQVQA 539 Query: 558 SGQAAPHFKNVELELDIKDLPITPFQHYFSNVLNVTLSSGLASAKGKLAITPPLQERKLA 617 SGQ + L++ +D+ + Q Y S + + L SG ++ LA+ E LA Sbjct: 540 SGQVVLDPVSARLKVSTRDIDLRVAQAYISPFIRLELRSGFLGSE--LAVDLKSVE-PLA 596 Query: 618 LDYKGSAAVTNLRMQDKRTGTDFLRWRTLELAGIQARLGGRPQVSLEKVTLANFYARAIL 677 GSA V+ L D DF++W L L G+ R +S++ V+ YAR I+ Sbjct: 597 FSVDGSAEVSQLHTLDTIKDRDFVKWTKLTLNGLAYR--HEDSLSIQSVSFEEPYARFII 654 Query: 678 SEQGRLNLQDIVVADAQQQGSITDDKKGSKEAPASSATNARKTTSTAAVTSAAPTADTPI 737 +E N+ ++++ PASS + TAA + AP + Sbjct: 655 NEDRSTNVSELIIPQ-----------------PASS------SGKTAAESKNAPASKPLG 691 Query: 738 VQVGQVVLQGGNINYTDNFVKPNYTANMTGLAGTIGQISSEKPQPAPVNISGKIDNDAPL 797 + +G V + G+ N+ D + P + + L+G +G + + QPA V+I GK+D AP+ Sbjct: 692 IHIGGVRINNGSANFADLTLMPPFGTAIQQLSGEVGTLDTRNSQPAKVDIKGKVDKYAPV 751 Query: 798 QISGALNPLFKPMY-LDLKASANGVQLPRLTPYSAKYAGYPITKGKLSMDVQYKIENDKL 856 I+G L+P F P+ LD+ S V+L LTPYS K+AGY I KG+L++D+ Y+IE +L Sbjct: 752 TIAGELDP-FDPLKKLDITTSFKRVELTTLTPYSGKFAGYRIRKGRLNLDLHYQIERSQL 810 Query: 857 VAQNDLRIEQLTFGERVDSPNATNLPVMLAVSLLKDREGNINLNLPISGSLSDPEFSVGG 916 A+N + +E L GE+VDSP+A +LPV LAV+LLKD +GNI++ LP++G L++PEFSV Sbjct: 811 KAENKVLLEGLQLGEKVDSPDAVDLPVKLAVALLKDTKGNIDIQLPVAGDLNNPEFSVMP 870 Query: 917 IIVRVFVNLIVKAVTSPFALIGSMFRADEHIGDLHYIAFAPGSSEIDDEVRKKLDALGYA 976 I+ + NL+++AV +PF I + DL + FA GS E+ E + LD L A Sbjct: 871 IVWQTLRNLVLRAVQAPFKFIAGLAAGGNE--DLGTVPFAAGSDELTPEAQANLDKLADA 928 Query: 977 LHERPGIKLDITGRVDPQVDDQGLRREALERKMRGL------KRADLIAKEGQPSGPVRI 1030 L ERP ++L++ G D + + LE + + +R D + PS ++ Sbjct: 929 LKERPALRLEVEGVASAAADGPSIGAKRLELEYQNTYYRMLQRRGDKV-----PSDAKQL 983 Query: 1031 SAAE--RGKYLERVYKDSTFDK-PRNMIGLTKSLPEAEMEKMILEHTDITQDDLRNLAQR 1087 E + LE +Y+ + P L A+M + ++ +Q LR + Q Sbjct: 984 EVPENMQAPLLEGIYRTRLKQQPPAEWKELDSDERTAKMREAVIASWAKSQVLLRQIGQA 1043 Query: 1088 RADQVRNYLQEQSIIEPARIFLI 1110 RA ++++YL E+ + RI+LI Sbjct: 1044 RATRIKDYLVEKGQLPDDRIYLI 1066 Score = 51.6 bits (122), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 77/336 (22%), Positives = 136/336 (40%), Gaps = 27/336 (8%) Query: 31 VLLTLAALSWAALPALVRKIAIDQTQAQIGRKLEIGQISFNPFKLALRASDITLYEADGK 90 L L + +P + ++A Q + +I FNPF L L + L E K Sbjct: 15 TFLVYCLLGFLLIPGIGLRVANQQLAQYATVPARLERIEFNPFSLELTLWGLRLGEE--K 72 Query: 91 RPFFSTQGLLADLSSASLLRLAPVLDEIKLTTPQLHLVRLDADGIGHYNFSDILDRL--A 148 P + + L A+L SL + L +++L P L+ + G N + + R+ + Sbjct: 73 NPQLAFRRLYANLQLDSLWKRQLHLADVELEGPHTELLFGEK---GQLNLASLF-RIPPS 128 Query: 149 AQPKSEGQAR---FSLANVQLQDGAIHFEDKVSGKNIDIAALQVGLPF--ISNLPGNIDS 203 P+ E + + +QL +G++HF+D + +D + +G +S LP D Sbjct: 129 ESPEPEQPSDPFPLRIDRIQLAEGSLHFQDLRPSEPVDFSFDPLGFELHNLSTLPD--DG 186 Query: 204 YVQPQLSAIINGTPLHLKGRSK--PFTASQESAFAIDIDQLDLVSYLPFVPAELPVAIQS 261 ++ NG L +G P T S + + + L ++ P+V P+ +++ Sbjct: 187 AKMTLVATGPNGGRLDWEGDLTLVPIT----SRGHLSVKDIQLKAWWPYVRDNAPLVLEN 242 Query: 262 AKLSTRLDLGFTRQDDKPTVTLAGDIRIDDIALQDKTRAPLLKAKSLALQLKQFDLLAAS 321 +S D D + +++ D ++ PL K SL + DL Sbjct: 243 GVVSLSSDYRLDLSKDTQLLLDKAALKLADFSINSPQGKPLAKLASLDVAATTLDLAKQE 302 Query: 322 ---GEVSQLTLEQPQVWASMNARGELNWVRAFASPT 354 GEV LE WA+ G+L+W + FA T Sbjct: 303 VVLGEVRSQGLE---AWAAREKDGQLDWQKLFADFT 335 Score = 32.3 bits (72), Expect = 7.4, Method: Compositional matrix adjust. Identities = 40/190 (21%), Positives = 77/190 (40%), Gaps = 14/190 (7%) Query: 297 KTRAPLLKAKSLALQLKQFDLLAASGEVSQLTLEQPQVWASMNARGELNWVRAFASPTKP 356 + + P L + L L+ L ++ + LE P +G+LN F P Sbjct: 70 EEKNPQLAFRRLYANLQLDSLWKRQLHLADVELEGPHTELLFGEKGQLNLASLFRIP--- 126 Query: 357 ASKGASSAPSKATTPAATTPAAAIVLQQLNLHGGEINWRDEANAAPAQTIKLSKVELNAA 416 PS++ P + + + ++ L G ++++D + P + Sbjct: 127 --------PSESPEPEQPSDPFPLRIDRIQLAEGSLHFQDLRPSEPVD-FSFDPLGFELH 177 Query: 417 QLSTAADAQPARLTLSAVENGHGKLGFDGQLQPLKPTLAGKITLDGVDLAGYQNYLA-RA 475 LST D A++TL A G+L ++G L + T G +++ + L + Y+ A Sbjct: 178 NLSTLPD-DGAKMTLVATGPNGGRLDWEGDLTLVPITSRGHLSVKDIQLKAWWPYVRDNA 236 Query: 476 PITDLSGKLS 485 P+ +G +S Sbjct: 237 PLVLENGVVS 246 >AGc3717 Non COG Length = 1234 Score = 40.4 bits (93), Expect = 0.027, Method: Compositional matrix adjust. Identities = 45/194 (23%), Positives = 85/194 (43%), Gaps = 39/194 (20%) Query: 279 PTVTLAGDIRIDDIALQDKTRAPLLKAKSLALQLKQFDLLAASGEVSQLTLEQPQVWASM 338 P+VTL D+R A D +PL++ ++ + L+ + + +E+P+ + Sbjct: 62 PSVTLH-DVR----AGTDADGSPLIQVARFSMDAELAPFLSGEARIFDMRIEEPKAKIRL 116 Query: 339 NARGELNWVRAFASPTKPASKGASSAPSKATTPAATTPAAAIVLQQLNLHGGEINWRDEA 398 G L+W+R S+A PA T +VL+ + + GG+I + DE Sbjct: 117 LKDGTLDWMRG----------------SRAEIPART-----VVLESVQIEGGQIEFIDEQ 155 Query: 399 NAAPAQTIKLSKVELNAAQLS--------TAADAQPARLTLSAVE--NGHGKLGFDGQLQ 448 + L+ +++A L+ A D P +LS+ E +G++G +L Sbjct: 156 SGRNRVVTGLN-ADMSANSLAGPWKAEGRAAVDGHPGSFSLSSSEPDYANGRMGLRLRLV 214 Query: 449 PLKPTLAGKITLDG 462 P + + ++ LDG Sbjct: 215 PDEHPV--EVDLDG 226 >PA2708 Non COG Length = 361 Score = 37.7 bits (86), Expect = 0.16, Method: Compositional matrix adjust. Identities = 28/133 (21%), Positives = 57/133 (42%), Gaps = 5/133 (3%) Query: 714 ATNARKTTSTAAVTSAAPTADTPI-VQVGQVVLQGGNINYTDNFVKPNYTANMTGLAGTI 772 A R + T A T D + + + +V + G + + + KP + + L +I Sbjct: 115 AGGDRDASQTGAGTDWREQLDKLLPITLNEVRVVDGTLRFRNFTSKPPVNLHASALNASI 174 Query: 773 GQISS----EKPQPAPVNISGKIDNDAPLQISGALNPLFKPMYLDLKASANGVQLPRLTP 828 +++ +PA + + +I APL+++ +PL DL+ V+L RL Sbjct: 175 YNLTNVADARGERPARLEGTARILGQAPLEVAAHFDPLSDFEDFDLRLRVTRVELKRLND 234 Query: 829 YSAKYAGYPITKG 841 +++ Y + G Sbjct: 235 FASAYGKFDFNAG 247 >SPBC577.06c [TDBLU] COG5032 Phosphatidylinositol kinase and protein kinases of the PI-3 kinase family Spo Schizosaccharomyces pombe Length = 1877 Score = 35.4 bits (80), Expect = 0.71, Method: Compositional matrix adjust. Identities = 20/50 (40%), Positives = 26/50 (52%), Gaps = 1/50 (2%) Query: 571 ELDIKD-LPITPFQHYFSNVLNVTLSSGLASAKGKLAITPPLQERKLALD 619 EL +K L P+ HY + V L SGL KG+L IT L+ L L+ Sbjct: 1792 ELCVKAFLACRPYAHYICQAVEVMLDSGLPCFKGQLTITHCLERFALNLN 1841