BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.3603.p (370 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0903 [HE] COG1932 Phosphoserine aminotransferase Rso Ralstoni... 510 e-144 PA3167 [HE] COG1932 Phosphoserine aminotransferase Pae Pseudomon... 438 e-122 YPO1389 [HE] COG1932 Phosphoserine aminotransferase Ype Yersinia... 421 e-117 STM0977 [HE] COG1932 Phosphoserine aminotransferase Sty Salmonel... 410 e-114 VC1159 [HE] COG1932 Phosphoserine aminotransferase Vch Vibrio ch... 409 e-114 >RSc0903 [HE] COG1932 Phosphoserine aminotransferase Rso Ralstonia solanacearum Length = 378 Score = 510 bits (1314), Expect = e-144, Method: Compositional matrix adjust. Identities = 244/366 (66%), Positives = 296/366 (80%), Gaps = 5/366 (1%) Query: 2 VYNFSAGPAVLPKEVLQQAADEMLDWHGSGMSVMEMSHRGKEYMSIIEAALADVRALMNI 61 VYNFSAGPAVLP EVL+QA +EML W GSGMSVMEMSHRG+E+ SI+ A AD+R L+ + Sbjct: 15 VYNFSAGPAVLPTEVLEQAREEMLSWQGSGMSVMEMSHRGREFESIMAQAFADLRELLAV 74 Query: 62 PSNYKVLFLQGGAIAENAIIPMNLAALRSPAGKHEAGVADYINTGSWSTKSIKEAGRYCT 121 P NY++LFLQGGAIAENAI+P+NL S +A ADY+ TG+WS KS +EA +Y Sbjct: 75 PDNYEILFLQGGAIAENAIVPLNLMRRLS----LDAPKADYVVTGTWSVKSQQEARKYGE 130 Query: 122 VNVAASSADRKFASIPARADWKLSRNAAYVHICSNETIDGVEYQYTPEVAADTDGAPLVA 181 VN+AASS +F IP + WKLS +AAYVH+C+NETI GVEYQ TP++ G +VA Sbjct: 131 VNIAASSEAERFHRIPDVSAWKLSDDAAYVHLCTNETIVGVEYQETPDIG-QAHGRVVVA 189 Query: 182 DMSSHILSREVDVSKYGVIYGGAQKNIGPAGVTIVIVREDLLGHALPFCPSAFDWKTVAD 241 D+SSHILSR VD + Y V+YGGAQKNIGPAG+TIVI R+DLLGHA P CPSAF+W+ VA+ Sbjct: 190 DVSSHILSRPVDWNGYAVLYGGAQKNIGPAGLTIVIARKDLLGHAHPLCPSAFNWRLVAE 249 Query: 242 HDSMYNTPPTYAIYIAGLVFQWIKRQGGVVALEARNIAKAELLYGYLDSTDFYSNRIAAD 301 + SMYNTPPTYAIY+AGLVFQWIKRQGGV ALE RNI KA++LY ++D++ FY N I Sbjct: 250 NGSMYNTPPTYAIYVAGLVFQWIKRQGGVEALETRNIVKAKMLYDFIDASGFYRNDIHPS 309 Query: 302 CRSRMNVPFFLRDESLNDTFLAGAKERGLLQLKGHKSVGGMRASIYNAMPIEGVQALVDY 361 CRSRMNVPFFL DES N+ FLA A+ +GL+QLKGHKSVGGMRASIYNAMP+EGV+ALVD+ Sbjct: 310 CRSRMNVPFFLNDESRNEAFLAQARAQGLVQLKGHKSVGGMRASIYNAMPLEGVEALVDF 369 Query: 362 LKDFER 367 +++FER Sbjct: 370 MREFER 375 >PA3167 [HE] COG1932 Phosphoserine aminotransferase Pae Pseudomonas aeruginosa Length = 361 Score = 438 bits (1127), Expect = e-122, Method: Compositional matrix adjust. Identities = 213/368 (57%), Positives = 274/368 (74%), Gaps = 12/368 (3%) Query: 3 YNFSAGPAVLPKEVLQQAADEMLDWHGSGMSVMEMSHRGKEYMSIIEAALADVRALMNIP 62 +NF AGPA LP VLQ+A E+LDW G G+SVMEMSHR +Y++I A D+R L++IP Sbjct: 6 FNFCAGPAALPDAVLQRAQAELLDWRGKGLSVMEMSHRSDDYVAIASKAEQDLRDLLDIP 65 Query: 63 SNYKVLFLQGGAIAENAIIPMNLAALRSPAGKHEAGVADYINTGSWSTKSIKEAGRYCTV 122 S+YKVLFLQGGA + A IP+NL E GVADYI+TG WS K+I+EA RY TV Sbjct: 66 SDYKVLFLQGGASQQFAEIPLNLLP--------EDGVADYIDTGIWSKKAIEEARRYGTV 117 Query: 123 NVAASSADRKFASIPARADWKLSRNAAYVHICSNETIDGVEYQYTPEVAADTDGAPLVAD 182 NVAAS+ + + +IP + +W L+++AAYVH SNETI G+E+ + PE T PLV D Sbjct: 118 NVAASAKEYDYFAIPGQNEWTLTKDAAYVHYASNETIGGLEFDWIPE----TGDVPLVTD 173 Query: 183 MSSHILSREVDVSKYGVIYGGAQKNIGPAGVTIVIVREDLLGHALPFCPSAFDWKTVADH 242 MSS ILSR +DVS++G+IY GAQKNIGP+G+ +VIVREDLLG A CP+ ++KT AD+ Sbjct: 174 MSSDILSRPLDVSRFGLIYAGAQKNIGPSGLVVVIVREDLLGRARSVCPTMLNYKTAADN 233 Query: 243 DSMYNTPPTYAIYIAGLVFQWIKRQGGVVALEARNIAKAELLYGYLDSTDFYSNRIAADC 302 SMYNTP TY+ Y++GLVF+W+K QGGV A+E RN AK +LLY +D++DFY+N I Sbjct: 234 GSMYNTPATYSWYLSGLVFEWLKEQGGVTAMEQRNRAKKDLLYKTIDASDFYTNPIQPSA 293 Query: 303 RSRMNVPFFLRDESLNDTFLAGAKERGLLQLKGHKSVGGMRASIYNAMPIEGVQALVDYL 362 RS MNVPF L DE L+ FL GA+ RGLL LKGH+SVGGMRASIYNA+ ++ V+ALV Y+ Sbjct: 294 RSWMNVPFRLADERLDKPFLEGAEARGLLNLKGHRSVGGMRASIYNALGLDAVEALVAYM 353 Query: 363 KDFERQHG 370 +FE++HG Sbjct: 354 AEFEKEHG 361 >YPO1389 [HE] COG1932 Phosphoserine aminotransferase Ype Yersinia pestis Length = 361 Score = 421 bits (1083), Expect = e-117, Method: Compositional matrix adjust. Identities = 211/370 (57%), Positives = 263/370 (71%), Gaps = 13/370 (3%) Query: 2 VYNFSAGPAVLPKEVLQQAADEMLDWHGSGMSVMEMSHRGKEYMSIIEAALADVRALMNI 61 VYNFSAGPA+LP EVL++A E+ +WHG G SVME+SHR KE+M + E + D+R L+ I Sbjct: 4 VYNFSAGPAMLPVEVLRRAEQELRNWHGLGTSVMEISHRSKEFMQVAEESEKDLRDLLQI 63 Query: 62 PSNYKVLFLQGGAIAENAIIPMNLAALRSPAGKHEAGVADYINTGSWSTKSIKEAGRYCT 121 P+NYKVLF GGA A+ A +P+NL R+ A DYI+ G W+ +IKEA +YCT Sbjct: 64 PANYKVLFCHGGARAQFAAVPLNLLGDRNSA--------DYIDGGYWAHSAIKEAQKYCT 115 Query: 122 VNVA-ASSADRKFASIPARADWKLSRNAAYVHICSNETIDGVEYQYTPEVAADTDGAPLV 180 NV ++ D I WKLS NAAYVH C NETIDGV P D +V Sbjct: 116 PNVIDVTTHDNGLTGIQPMKQWKLSDNAAYVHYCPNETIDGVAINEQP----DFGNKVVV 171 Query: 181 ADMSSHILSREVDVSKYGVIYGGAQKNIGPAGVTIVIVREDLLGHALPFCPSAFDWKTVA 240 AD SS ILSR +D+S+YGVIY GAQKNIGPAG+T+VIVREDLLG A PS D+K +A Sbjct: 172 ADYSSSILSRPIDISRYGVIYAGAQKNIGPAGLTLVIVREDLLGKAHTALPSILDYKVLA 231 Query: 241 DHDSMYNTPPTYAIYIAGLVFQWIKRQGGVVALEARNIAKAELLYGYLDSTDFYSNRIAA 300 D+DSM+NTPPT+A Y++GLVF+W+K QGG+ +E RN AKAELLYG +D T FY N++A Sbjct: 232 DNDSMFNTPPTFAWYLSGLVFKWLKEQGGLGEMEKRNQAKAELLYGAIDRTGFYRNQVAI 291 Query: 301 DCRSRMNVPFFLRDESLNDTFLAGAKERGLLQLKGHKSVGGMRASIYNAMPIEGVQALVD 360 RS MNVPF + D SL+ FL+ A+ +GL LKGH+ GGMRASIYNAMPIEGV+AL D Sbjct: 292 TNRSWMNVPFQMADASLDKLFLSEAEAQGLQALKGHRVAGGMRASIYNAMPIEGVKALTD 351 Query: 361 YLKDFERQHG 370 ++ DFER+HG Sbjct: 352 FMADFERRHG 361 >STM0977 [HE] COG1932 Phosphoserine aminotransferase Sty Salmonella typhimurium LT2 Length = 362 Score = 410 bits (1054), Expect = e-114, Method: Compositional matrix adjust. Identities = 205/371 (55%), Positives = 260/371 (70%), Gaps = 14/371 (3%) Query: 2 VYNFSAGPAVLPKEVLQQAADEMLDWHGSGMSVMEMSHRGKEYMSIIEAALADVRALMNI 61 V+NFS+GPA+LP EVL+ A E+ DWHG G SVME+SHRGKE++ + E A D R L+NI Sbjct: 4 VFNFSSGPAMLPAEVLKLAQQELCDWHGLGTSVMEISHRGKEFIQVAEEAEQDFRDLLNI 63 Query: 62 PSNYKVLFLQGGAIAENAIIPMNLAALRSPAGKHEAGVADYINTGSWSTKSIKEAGRYCT 121 PSNYKVLF GG + A +P+NL ++ ADY++ G W+ +IKEA +YC Sbjct: 64 PSNYKVLFCHGGGRGQFAGVPLNLLGDKT--------TADYVDAGYWAASAIKEAKKYCA 115 Query: 122 VNV--AASSADRKFASIPARADWKLSRNAAYVHICSNETIDGVEYQYTPEVAADTDGAPL 179 + A + D K A P R +W+LS NAAY+H C NETIDG+ TP+ + + Sbjct: 116 PQIIDAKITVDGKRAVKPMR-EWQLSDNAAYLHYCPNETIDGIAIDETPDFGPEV---VV 171 Query: 180 VADMSSHILSREVDVSKYGVIYGGAQKNIGPAGVTIVIVREDLLGHALPFCPSAFDWKTV 239 AD SS ILS +DVS+YGVIY GAQKNIGPAG+T+VIVREDLLG A CPS D+ + Sbjct: 172 TADFSSTILSAPLDVSRYGVIYAGAQKNIGPAGLTLVIVREDLLGKAHESCPSILDYTVL 231 Query: 240 ADHDSMYNTPPTYAIYIAGLVFQWIKRQGGVVALEARNIAKAELLYGYLDSTDFYSNRIA 299 D+DSM+NTPPT+A Y++GLVF+W+K QGGV A+ N KAELLYG +D++DFY N +A Sbjct: 232 NDNDSMFNTPPTFAWYLSGLVFKWLKAQGGVAAMHKINQQKAELLYGVIDNSDFYRNDVA 291 Query: 300 ADCRSRMNVPFFLRDESLNDTFLAGAKERGLLQLKGHKSVGGMRASIYNAMPIEGVQALV 359 RSRMNVPF L D +L+ FL + GL LKGH+ VGGMRASIYNAMPIEGV+AL Sbjct: 292 QANRSRMNVPFQLADNTLDKVFLEESFAAGLHALKGHRVVGGMRASIYNAMPIEGVKALT 351 Query: 360 DYLKDFERQHG 370 D++ DFER+HG Sbjct: 352 DFMIDFERRHG 362 >VC1159 [HE] COG1932 Phosphoserine aminotransferase Vch Vibrio cholerae Length = 379 Score = 409 bits (1052), Expect = e-114, Method: Compositional matrix adjust. Identities = 209/371 (56%), Positives = 266/371 (71%), Gaps = 16/371 (4%) Query: 2 VYNFSAGPAVLPKEVLQQAADEMLDWHGSGMSVMEMSHRGKEYMSIIEAALADVRALMNI 61 VYNFSAGPA LPK V+ QA E ++W+ G SVME+SHR + ++ + E A D+R L+NI Sbjct: 23 VYNFSAGPAALPKAVMLQAQAEFVNWNHLGTSVMEISHRSQPFIQVAEHAERDLRDLLNI 82 Query: 62 PSNYKVLFLQGGAIAENAIIPMNLAALRSPAGKHEAGVADYINTGSWSTKSIKEAGRYCT 121 P NYKVLF QGGA A+ A +P+NL +A A YI+ G W+ ++KEA +YCT Sbjct: 83 PDNYKVLFCQGGARAQFAAVPLNLLG--------DAETATYIDAGYWAMSAVKEAKKYCT 134 Query: 122 VNVAASSADR--KFASIPARADWKLSRNAAYVHICSNETIDGVEYQYTPEVAADTDGAPL 179 V+V + ++ K A +PA ++W+++ NAAYVH C NETIDG+E P P+ Sbjct: 135 VDVFDAKIEKEGKIAVLPA-SEWRIANNAAYVHFCPNETIDGIEINDLP-----VTDKPI 188 Query: 180 VADMSSHILSREVDVSKYGVIYGGAQKNIGPAGVTIVIVREDLLGHALPFCPSAFDWKTV 239 VADMSS ILSRE+DVSKYGVIY GAQKNIGPAG+ I IVR+DLL A P ++K + Sbjct: 189 VADMSSTILSREIDVSKYGVIYAGAQKNIGPAGICIAIVRDDLLDLASDLLPGVLNYKIL 248 Query: 240 ADHDSMYNTPPTYAIYIAGLVFQWIKRQGGVVALEARNIAKAELLYGYLDSTDFYSNRIA 299 A+ +SM+NTPPT+A Y++GLVFQW+K QGGV A+E N AKA LLYGY+DS+DFY N I Sbjct: 249 AEQESMFNTPPTFAWYLSGLVFQWLKAQGGVKAIEEVNRAKAALLYGYIDSSDFYRNEIH 308 Query: 300 ADCRSRMNVPFFLRDESLNDTFLAGAKERGLLQLKGHKSVGGMRASIYNAMPIEGVQALV 359 D RS MNVPF L L+DTFL A+ RGL+ LKGH+ VGGMRASIYNAMP+EGVQALV Sbjct: 309 PDNRSLMNVPFQLAKPELDDTFLELAEARGLVSLKGHRVVGGMRASIYNAMPLEGVQALV 368 Query: 360 DYLKDFERQHG 370 D++K+FE Q+ Sbjct: 369 DFMKEFEAQYA 379