BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.3601.p (295 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0906 [E] COG0287 Prephenate dehydrogenase Rso Ralstonia solan... 295 1e-79 PA3164_1 [E] COG0287 Prephenate dehydrogenase Pae Pseudomonas ae... 226 6e-59 BMEI0079 [E] COG0287 Prephenate dehydrogenase Bme Brucella melit... 224 2e-58 mll3535 [E] COG0287 Prephenate dehydrogenase Mlo Mesorhizobium loti 222 1e-57 NMA2045 [E] COG0287 Prephenate dehydrogenase NmA Neisseria menin... 217 3e-56 >RSc0906 [E] COG0287 Prephenate dehydrogenase Rso Ralstonia solanacearum Length = 298 Score = 295 bits (754), Expect = 1e-79, Method: Compositional matrix adjust. Identities = 164/281 (58%), Positives = 200/281 (71%), Gaps = 1/281 (0%) Query: 3 KKVVIFGVGLIGGSFALALRRAGQVAHIVGVGRSVQSLERARELGIIDAFATDVAAAVAG 62 ++VI GVGLIGGS ALALRRAG V ++GVGRS SLE A LG+ID A + AAV G Sbjct: 8 SRLVIVGVGLIGGSLALALRRAGVVGQVIGVGRSGASLEAAVRLGVIDE-ALPMEAAVRG 66 Query: 63 ADLILVAAPVAQTESILASIAPHLGEQAIVTDAGSTKSDVVASARKALGARIAQFIPAHP 122 AD++++ APVAQT +L ++ PHLG IVTDAGSTKSDV+ +A+ ALG +++QF+PAHP Sbjct: 67 ADMVVLCAPVAQTLPLLLAMQPHLGPDTIVTDAGSTKSDVIMAAKTALGDQVSQFVPAHP 126 Query: 123 IAGREKHGPEAALAELYEGKKVVITALPENTEADVETVAAAWRACGAVIHRLSAQQHDAV 182 IAGRE +G EAALA+LY GKK V+ L EN ADV V A W A GA H +SA QHDAV Sbjct: 127 IAGRELNGVEAALADLYVGKKTVLCPLQENRRADVARVQAMWDAAGAYCHVMSAVQHDAV 186 Query: 183 FASVSHLPHVLAFALVDDIAAKPHAETLFQYAASGFRDFTRIAASSPEMWRDITLANRAA 242 FA+VSHLPHVL++ALV I A +A GFRDFTRIAASSPEMWRDI L+NR A Sbjct: 187 FAAVSHLPHVLSYALVAQIINAEDAALKLDFAGGGFRDFTRIAASSPEMWRDICLSNREA 246 Query: 243 LLTEVDAYLVQLQGIREMIAAGDGAAIEQVYANAQHARLQW 283 LL E+ Y + ++ MIA D A+E+V+ A ARL W Sbjct: 247 LLRELTTYEAVVGRLKAMIAERDAEALERVFRRASEARLAW 287 >PA3164_1 [E] COG0287 Prephenate dehydrogenase Pae Pseudomonas aeruginosa Length = 319 Score = 226 bits (575), Expect = 6e-59, Method: Compositional matrix adjust. Identities = 122/282 (43%), Positives = 170/282 (60%), Gaps = 2/282 (0%) Query: 4 KVVIFGVGLIGGSFALALRRAGQVAHIVGVGRSVQSLERARELGIIDAFATDVAAAVAGA 63 ++V+ G+GLIGGSFA LR G +VGV R +S A ELG++D D+ A GA Sbjct: 16 RLVVVGLGLIGGSFAKGLRSKGLFREVVGVDRDAESCRLAVELGVVDRCEEDLGRACVGA 75 Query: 64 DLILVAAPVAQTESILASIAPHLGEQAIVTDAGSTKSDVVASARKALGARIAQFIPAHPI 123 D++ +A P+ E +LA +A +A++TD GS K ++V +AR A G +P HPI Sbjct: 76 DVVQLAVPILAMERVLADLAKLDLGKAVLTDVGSAKGNIVRAARVAFGGMPRYLVPGHPI 135 Query: 124 AGREKHGPEAALAELYEGKKVVITALPENTEAD-VETVAAAWRACGAVIHRLSAQQHDAV 182 AG E+ G AA A L+ KV++T E T+AD + V + WRA GA + + + HD V Sbjct: 136 AGSEQSGVTAAKATLFRRHKVILTPSAE-TDADALALVDSLWRALGADVEHMEVEHHDEV 194 Query: 183 FASVSHLPHVLAFALVDDIAAKPHAETLFQYAASGFRDFTRIAASSPEMWRDITLANRAA 242 A+ SHLPH+LAF LVD +A + +F+YAA GFRDFTRIA S P MW DI LANR A Sbjct: 195 LAATSHLPHLLAFTLVDSLAKRSENLEIFRYAAGGFRDFTRIAGSDPVMWHDIFLANREA 254 Query: 243 LLTEVDAYLVQLQGIREMIAAGDGAAIEQVYANAQHARLQWA 284 +L +D + L +RE + GDG + V+ A+ AR ++ Sbjct: 255 VLRTLDVFRDDLDALREAVDTGDGHQLLGVFTRARVAREHFS 296 >BMEI0079 [E] COG0287 Prephenate dehydrogenase Bme Brucella melitensis Length = 321 Score = 224 bits (570), Expect = 2e-58, Method: Compositional matrix adjust. Identities = 114/279 (40%), Positives = 169/279 (60%), Gaps = 5/279 (1%) Query: 2 FKKVVIFGVGLIGGSFALALRRAGQVAHIVGVGRSVQSLERARELGIIDAFATDVAAAVA 61 F K+ + G+GLIG S A +RR G HI RS ++L+RA EL + D++ T+ A AV Sbjct: 6 FDKITLIGIGLIGSSLARVIRREGLATHIAIATRSAETLKRAEELNLGDSYTTNSAEAVK 65 Query: 62 GADLILVAAPVAQTESILASIAPHLGEQAIVTDAGSTKSDVVASARKALGARIAQFIPAH 121 ADL++V+ PV + ++ IA +L AIVTD GSTK+ V+A + L + FIP H Sbjct: 66 DADLVIVSVPVGSSGTVARQIAGNLKPGAIVTDVGSTKASVIAQMQPELPENM-HFIPGH 124 Query: 122 PIAGREKHGPEAALAELYEGKKVVITALPENTEADVETVAAAWRACGAVIHRLSAQQHDA 181 P+AG E GP+A AEL+ + ++T LP+ E +E + A W ACG+ + + Q HD Sbjct: 125 PLAGTEYSGPDAGFAELFTNRWCILTPLPDTDEKALEKLTAFWTACGSRLDHMDPQHHDL 184 Query: 182 VFASVSHLPHVLAFALV---DDIAAKPHAETLFQYAASGFRDFTRIAASSPEMWRDITLA 238 V A VSHLPH++A+ +V D+ +E + +Y+ASGFRDFTR+AAS P MWRD+ L Sbjct: 185 VLAIVSHLPHIIAYNIVGTASDLELVTKSEVI-KYSASGFRDFTRLAASDPTMWRDVCLH 243 Query: 239 NRAALLTEVDAYLVQLQGIREMIAAGDGAAIEQVYANAQ 277 N+ A+L + + L ++ I GDG A+ ++ + Sbjct: 244 NKDAILEMLGRFSEDLASLQRSIRWGDGEALFDLFTRTR 282 >mll3535 [E] COG0287 Prephenate dehydrogenase Mlo Mesorhizobium loti Length = 311 Score = 222 bits (565), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 113/283 (39%), Positives = 170/283 (60%), Gaps = 5/283 (1%) Query: 1 VFKKVVIFGVGLIGGSFALALRRAGQVAHIVGVGRSVQSLERARELGIIDAFATDVAAAV 60 +F+K+ + G+GLIG S A +RR G H+ RS +L+RA ELG+ D++ TD AV Sbjct: 5 MFEKIALVGIGLIGSSLARVIRREGLAGHVAISTRSATTLKRAEELGLGDSYTTDAKEAV 64 Query: 61 AGADLILVAAPVAQTESILASIAPHLGEQAIVTDAGSTKSDVVASARKALGARIAQFIPA 120 ADL++V+ PV + ++ IAP L + AI+TD GSTK+ V+A + + + FIP Sbjct: 65 RDADLVIVSVPVGSSGAVAEEIAPALKKGAILTDVGSTKASVIAQMQPHVPDGV-HFIPG 123 Query: 121 HPIAGREKHGPEAALAELYEGKKVVITALPENTEADVETVAAAWRACGAVIHRLSAQQHD 180 HP+AG EK GP+A A+L++ + + T LP +E ++ WR CGA I + Q HD Sbjct: 124 HPLAGTEKSGPDAGFADLFDNRWCIFTPLPGTDPEALERLSEFWRRCGANIDTMDPQHHD 183 Query: 181 AVFASVSHLPHVLAFALV---DDIAAKPHAETLFQYAASGFRDFTRIAASSPEMWRDITL 237 A VSHLPH++A+ +V DD+ + E + +Y+ASGFRDFTR+AAS P MWRD+ L Sbjct: 184 MTLAIVSHLPHIIAYNIVGTADDLESVTKTEVI-KYSASGFRDFTRLAASDPTMWRDVCL 242 Query: 238 ANRAALLTEVDAYLVQLQGIREMIAAGDGAAIEQVYANAQHAR 280 N+ A+L + + L ++ I GDG + ++ + R Sbjct: 243 HNKDAILEMLARFSEDLAFLQRAIRWGDGDKLFDLFTRTRAVR 285 >NMA2045 [E] COG0287 Prephenate dehydrogenase NmA Neisseria meningitidis Z2491 Length = 290 Score = 217 bits (552), Expect = 3e-56, Method: Compositional matrix adjust. Identities = 117/285 (41%), Positives = 172/285 (60%), Gaps = 3/285 (1%) Query: 1 VFKKVVIFGVGLIGGSFALALRRAGQVAHIVGVGRSVQSLERARELGIID--AFATDVAA 58 + + + GVGLIGGSF L L+R G V + G+ +LERA E G+ID + A D A Sbjct: 3 ILNHIALIGVGLIGGSFVLDLKRQGLVRTVTGIDTDRDNLERALERGVIDRASVAID-AD 61 Query: 59 AVAGADLILVAAPVAQTESILASIAPHLGEQAIVTDAGSTKSDVVASARKALGARIAQFI 118 ++ GADL+L+A PVA +IL ++ P L E ++D GSTKS V+ + R+ L R+ + I Sbjct: 62 SIGGADLVLIATPVATVPAILTALRPVLPEHTWISDVGSTKSSVIEAFRRCLPDRLHRCI 121 Query: 119 PAHPIAGREKHGPEAALAELYEGKKVVITALPENTEADVETVAAAWRACGAVIHRLSAQQ 178 AHPIAG ++ G +AA L+ +K++IT + + W A GA I+ + AQ+ Sbjct: 122 AAHPIAGSDRSGAQAAQFGLFRHRKLIITPHGGEHSDGIALIENLWHAVGAEIYTMDAQR 181 Query: 179 HDAVFASVSHLPHVLAFALVDDIAAKPHAETLFQYAASGFRDFTRIAASSPEMWRDITLA 238 HDAVFA+VSH+PH+ AFA V I P + ++AA+GFRDFTRIA+ P +W DI LA Sbjct: 182 HDAVFAAVSHMPHLTAFAYVHQILDHPDGQEYLKFAATGFRDFTRIASGHPAVWADICLA 241 Query: 239 NRAALLTEVDAYLVQLQGIREMIAAGDGAAIEQVYANAQHARLQW 283 N+ +LL V QL + +++ A D A+ + + A+ R +W Sbjct: 242 NKDSLLQLVQGLGKQLDVLADILTADDREALYRYFEEAKTTRDRW 286