BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.3599.p (222 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0908 [F] COG0283 Cytidylate kinase Rso Ralstonia solanacearum 253 3e-67 PA3163 [F] COG0283 Cytidylate kinase Pae Pseudomonas aeruginosa 205 6e-53 VC1916 [F] COG0283 Cytidylate kinase Vch Vibrio cholerae 204 2e-52 HI1219 [F] COG0283 Cytidylate kinase Hin Haemophilus influenzae 202 6e-52 YPO1391 [F] COG0283 Cytidylate kinase Ype Yersinia pestis 196 3e-50 >RSc0908 [F] COG0283 Cytidylate kinase Rso Ralstonia solanacearum Length = 230 Score = 253 bits (646), Expect = 3e-67, Method: Compositional matrix adjust. Identities = 132/211 (62%), Positives = 152/211 (72%) Query: 7 PVITIDGPTASGKGTVAQKVARELGFHYLDSGALYRLTALSVLRRGIALNDEHALAKAAE 66 PVI IDGPTASGKGTVA ++A LGFHYLDSG+LYRL A +R I +D ++L + A Sbjct: 11 PVIAIDGPTASGKGTVAHQIADLLGFHYLDSGSLYRLVAFVSIRENIDDHDVNSLVRIAS 70 Query: 67 HLHCHFDGAHIFLANEDVTQAIRAEEVGNTASKIAALITVRQALYGLQLSFRKPPGLVAD 126 L F HI+L EDV+ A+R E VGN AS IA VR+AL Q +F + PGLVAD Sbjct: 71 ELDVRFKADHIWLKGEDVSLALRHESVGNQASAIAVHGPVREALRARQRAFLEAPGLVAD 130 Query: 127 GRDMGTVIFPTARLKVFLTASVEARAIRRYKQLIDKGFSANIEDLSRDLKERDERDMNRS 186 GRDMGTVIFP A LKVFLTASV+ARA RRYKQLI KGFSA +E LSRDL+ RD RD RS Sbjct: 131 GRDMGTVIFPEAVLKVFLTASVQARAERRYKQLIAKGFSATVESLSRDLEARDLRDRTRS 190 Query: 187 SAPLKAAEGAYHLDTSDMTADEAVQQVLSWY 217 APL+ AE A LD+SDM+ DE V QVL WY Sbjct: 191 VAPLRPAEAARLLDSSDMSVDEVVAQVLDWY 221 >PA3163 [F] COG0283 Cytidylate kinase Pae Pseudomonas aeruginosa Length = 229 Score = 205 bits (522), Expect = 6e-53, Method: Compositional matrix adjust. Identities = 110/215 (51%), Positives = 145/215 (67%), Gaps = 6/215 (2%) Query: 6 IPVITIDGPTASGKGTVAQKVARELGFHYLDSGALYRLTALSVLRRGIALNDEHALAKAA 65 +P++ IDGP+ +GKGTVA +AR LG++ LDSGALYRL A + + G+ L +E AL A Sbjct: 5 VPMLAIDGPSGAGKGTVAGLLARRLGWNLLDSGALYRLLAFAAVNHGVDLTNEEALKVLA 64 Query: 66 EHLHCHF---DGAH---IFLANEDVTQAIRAEEVGNTASKIAALITVRQALYGLQLSFRK 119 HL F DG+H I L E+VT IR E+VG AS++AAL VR AL Q +FR+ Sbjct: 65 AHLDVQFVAADGSHGQRIILEGEEVTDVIRTEQVGAGASQVAALPAVRDALLQRQRAFRE 124 Query: 120 PPGLVADGRDMGTVIFPTARLKVFLTASVEARAIRRYKQLIDKGFSANIEDLSRDLKERD 179 PGLVADGRDMGTV+FP A LK+FLTAS E RA RRY QL KG + L +++ERD Sbjct: 125 APGLVADGRDMGTVVFPDAPLKIFLTASAEERARRRYLQLKAKGADVDQSALLEEIRERD 184 Query: 180 ERDMNRSSAPLKAAEGAYHLDTSDMTADEAVQQVL 214 ERD R+ APLK A+ A LD+++M+ + V+ ++ Sbjct: 185 ERDSQRAVAPLKPADDAILLDSTEMSIEAVVETII 219 >VC1916 [F] COG0283 Cytidylate kinase Vch Vibrio cholerae Length = 229 Score = 204 bits (518), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 109/223 (48%), Positives = 144/223 (64%), Gaps = 7/223 (3%) Query: 1 MEK---AKIPVITIDGPTASGKGTVAQKVARELGFHYLDSGALYRLTALSVLRRGIALND 57 MEK + PV+T+DGP+ +GKGT+ +A++LGF LDSGA+YR+ AL+ L G+ L Sbjct: 1 MEKYMSSHTPVVTVDGPSGAGKGTLCMLLAKKLGFQLLDSGAIYRVLALAALHHGVDLES 60 Query: 58 EHALAKAAEHLHCHF----DGAHIFLANEDVTQAIRAEEVGNTASKIAALITVRQALYGL 113 E AL A HL F D + L EDV++ +R EE G ASK+AAL VR+AL Sbjct: 61 EDALVPLATHLDVQFIAEGDLVKVILEGEDVSRELRKEETGMAASKVAALPRVREALLRR 120 Query: 114 QLSFRKPPGLVADGRDMGTVIFPTARLKVFLTASVEARAIRRYKQLIDKGFSANIEDLSR 173 Q +F GLVADGRDMGTV+FP A K+FL AS E RA RR+KQL KG + L Sbjct: 121 QRAFASGIGLVADGRDMGTVVFPAAEAKIFLDASAEERARRRFKQLQLKGLDVKFDALLS 180 Query: 174 DLKERDERDMNRSSAPLKAAEGAYHLDTSDMTADEAVQQVLSW 216 +++ERD+RD NR+ APL+ AE A LD++ +T DE V+Q L + Sbjct: 181 EIQERDDRDRNRAVAPLRPAEDALVLDSTTLTIDEVVEQALQY 223 >HI1219 [F] COG0283 Cytidylate kinase Hin Haemophilus influenzae Length = 231 Score = 202 bits (513), Expect = 6e-52, Method: Compositional matrix adjust. Identities = 106/218 (48%), Positives = 144/218 (66%), Gaps = 4/218 (1%) Query: 8 VITIDGPTASGKGTVAQKVARELGFHYLDSGALYRLTALSVLRRGIALNDEHALAKAAEH 67 +IT+DGP+ +GKGT+ +A +LG+ LDSGA+YR+TAL+ L+R L +E LA+ A H Sbjct: 2 IITVDGPSGAGKGTLCYALAEKLGYALLDSGAIYRVTALAALQRKTDLTNETDLAELARH 61 Query: 68 LHCHF---DG-AHIFLANEDVTQAIRAEEVGNTASKIAALITVRQALYGLQLSFRKPPGL 123 L F +G I LA DV++ IR +EV + ASK+A VR AL LQ F K GL Sbjct: 62 LDIQFIPQNGEVSILLAGMDVSRLIRTQEVADAASKVAVFQKVRSALLQLQQDFAKNDGL 121 Query: 124 VADGRDMGTVIFPTARLKVFLTASVEARAIRRYKQLIDKGFSANIEDLSRDLKERDERDM 183 +ADGRDMGTV+FP A++K+FL AS E RA RRYKQL +KG + N + ++KERD RD Sbjct: 122 IADGRDMGTVVFPNAQVKLFLDASAEERAKRRYKQLQNKGINGNFAQILAEIKERDFRDR 181 Query: 184 NRSSAPLKAAEGAYHLDTSDMTADEAVQQVLSWYAALG 221 NR APLK A+ A LD++ ++ DE + Q L++ G Sbjct: 182 NREVAPLKPADDALLLDSTTLSIDEVIDQALAYIQRXG 219 >YPO1391 [F] COG0283 Cytidylate kinase Ype Yersinia pestis Length = 230 Score = 196 bits (499), Expect = 3e-50, Method: Compositional matrix adjust. Identities = 100/214 (46%), Positives = 141/214 (65%), Gaps = 4/214 (1%) Query: 7 PVITIDGPTASGKGTVAQKVARELGFHYLDSGALYRLTALSVLRRGIALNDEHALAKAAE 66 PVIT+DGP+ +GKGT+ + +A L + LDSGA+YR+ AL+ L + ++ E AL A Sbjct: 6 PVITVDGPSGAGKGTLCKALAESLNWRLLDSGAIYRVLALAALHHQVDISTEEALVPLAA 65 Query: 67 HLHCHFDGAH----IFLANEDVTQAIRAEEVGNTASKIAALITVRQALYGLQLSFRKPPG 122 HL F + + L EDV+ IR E VGNTAS+ AA VR+AL Q +FR+ PG Sbjct: 66 HLDVRFVSQNGQLQVILEGEDVSNEIRTETVGNTASQAAAFPRVREALLRRQRAFREAPG 125 Query: 123 LVADGRDMGTVIFPTARLKVFLTASVEARAIRRYKQLIDKGFSANIEDLSRDLKERDERD 182 L+ADGRDMGT++FP A +K+FL AS + RA RR QL ++GF+ N E L +++ERD RD Sbjct: 126 LIADGRDMGTIVFPDAPVKIFLDASSQERAHRRMLQLQERGFNVNFERLLAEIQERDNRD 185 Query: 183 MNRSSAPLKAAEGAYHLDTSDMTADEAVQQVLSW 216 NRS APL A A LD++ M+ ++ ++Q L++ Sbjct: 186 RNRSVAPLVPAADALVLDSTSMSIEQVIEQALAY 219