BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.3556.p (1242 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0974 [C] COG5013 Nitrate reductase alpha subunit Rso Ralstoni... 2117 0.0 STM1764 [C] COG5013 Nitrate reductase alpha subunit Sty Salmonel... 1768 0.0 narG [C] COG5013 Nitrate reductase alpha subunit Eco Escherichia... 1766 0.0 ZnarG [C] COG5013 Nitrate reductase alpha subunit EcZ Escherichi... 1765 0.0 ECs1729 [C] COG5013 Nitrate reductase alpha subunit Ecs Escheric... 1765 0.0 >RSp0974 [C] COG5013 Nitrate reductase alpha subunit Rso Ralstonia solanacearum Length = 1245 Score = 2117 bits (5486), Expect = 0.0, Method: Compositional matrix adjust. Identities = 1002/1240 (80%), Positives = 1091/1240 (87%), Gaps = 4/1240 (0%) Query: 1 MSHFLDRLKFMSRVKSTFADGHGAVVNEDRQWENAYRSRWQHDKEVRSTHGVNCTGSCSW 60 MSHFLDRLKF++ V+STFADGHGAVVNEDR+WE+ YRSRWQHDK VRSTHGVNCTGSCSW Sbjct: 1 MSHFLDRLKFLTHVRSTFADGHGAVVNEDRRWEDGYRSRWQHDKIVRSTHGVNCTGSCSW 60 Query: 61 KVYVKNGLITWETQQTDYPRTRPDLPNHEPRGCPRGASYSWYVYSAQRVKYPMIRGRLMQ 120 KVYVKNGLITWETQQTDYPRTRPDLPNHEPRGCPRGASYSWYVYSAQRVK P+IRGRLMQ Sbjct: 61 KVYVKNGLITWETQQTDYPRTRPDLPNHEPRGCPRGASYSWYVYSAQRVKTPLIRGRLMQ 120 Query: 121 LWQEARRTLSPVEAWAAITSDAAKATSYKSVRGLGGFVRADWDTANEIIAAANAYTIKQY 180 +W+EAR+T+ PV AW +I+ + KA YKSVRG GGFVRADWDTA EIIAAANAYTIK+Y Sbjct: 121 MWREARKTMDPVAAWESISQNPEKAKRYKSVRGQGGFVRADWDTATEIIAAANAYTIKRY 180 Query: 181 GPDRVIGFSPIPAMSMVSYAAGARYLSLIGGVPLSFYDWYCDLPPASPQIWGEQTDVPES 240 GPDRV+GFSPIPAMSMVSYAAGARYLSLIGGV LSFYDWYCDLPPASPQ+WGEQTDVPES Sbjct: 181 GPDRVVGFSPIPAMSMVSYAAGARYLSLIGGVCLSFYDWYCDLPPASPQVWGEQTDVPES 240 Query: 241 ADWYNSTYLMVWGSNVPQTRTPDAHFYTEVRYKGTKTVAVSSDFGEMVKFGDIWLAPKQG 300 ADWYNSTYLMVWGSNVPQTRTPDAHFYTEVRYKGTKTVA+SSD+GEMVKFGDIWLAPKQG Sbjct: 241 ADWYNSTYLMVWGSNVPQTRTPDAHFYTEVRYKGTKTVAISSDYGEMVKFGDIWLAPKQG 300 Query: 301 TDAALAMAMGHVVLKEFHQAQPSAYFRSYVKQYTDMPMLVRLVQ-RDGHYLPDHLLRASQ 359 TDAALAMAMGHVVLKEFH SAYFR YVKQYTDMPMLV L + +G Y DH LRAS Sbjct: 301 TDAALAMAMGHVVLKEFHATGKSAYFRDYVKQYTDMPMLVLLREAENGSYTSDHFLRASH 360 Query: 360 LPDQLEEANNADWKSLAIDASTGQIVAPNGSIGYRWGEGQVNDGAKVGRWNLESRDGHSG 419 L EANN DWK+L IDA TG++V PNG+IG RW E Q + GAKVGRWNLE +D G Sbjct: 361 LAGNHGEANNPDWKTLLIDAPTGRLVVPNGTIGLRWNEAQHDGGAKVGRWNLELKDAADG 420 Query: 420 REIDPLLSLVAQHDEVVTVAFNYFGGDDAQPLALRQVPVRHVRLADGSTALVATVHDLMM 479 IDPLLSL HDEVV V F YFGG+ L LR+VPV+ V LADGSTA +ATV+DL + Sbjct: 421 AAIDPLLSLTGAHDEVVDVGFPYFGGEHDARL-LRRVPVKRVTLADGSTARIATVYDLQL 479 Query: 480 ANYGVDQGLGG-EIARSYDDDVPYTPAWQEKHTGVKRELVIQVAREFAQNAHDTQGKSMV 538 ANYGVDQGLGG +A +DDDVPYTPAWQEKHTGV R+ VIQVAREFA NA T+GKSMV Sbjct: 480 ANYGVDQGLGGPNVAAGFDDDVPYTPAWQEKHTGVPRQQVIQVAREFADNADRTRGKSMV 539 Query: 539 IVGAALNHWYHNDMIYRGIINLLMMCGCIGKSGGGWAHYVGQEKLRPQFGWAPLAFATDW 598 IVGAALNHWYHNDMIYRGIINLLMMCGCIG+SGGGWAHYVGQEKLRPQFGWAPLAF DW Sbjct: 540 IVGAALNHWYHNDMIYRGIINLLMMCGCIGQSGGGWAHYVGQEKLRPQFGWAPLAFGLDW 599 Query: 599 VRPPRQMNGTSFFYAHTSQWRHEKLGIDEIVAPTADKDKLSSMSMIDMNAKSERMGWLPS 658 RPPRQMNGTSFFY+HTSQWRHEKL +DEI++PTAD+ + +S++D+NA+SERMGWLPS Sbjct: 600 SRPPRQMNGTSFFYSHTSQWRHEKLSVDEILSPTADRTRYDGLSLLDLNARSERMGWLPS 659 Query: 659 APQLETNPLDICDNARAMGQTPQDYLKEALKSGTVNMSCDDPDNPKNFPRNMFVWRSNIL 718 APQL NPLD+ D A+A GQ P Y E LK+G + +C+DPD+P NFPRNMFVWRSNIL Sbjct: 660 APQLNANPLDVTDAAQAAGQEPVAYTVEQLKAGKLRFACEDPDHPDNFPRNMFVWRSNIL 719 Query: 719 GSSGKGHEYFLKYLLGTQNALFDNPDEAIKPSEVKYREQAAEGKLDLLVTLDFRMSTTCL 778 GSSGKGHEYFLKYLLGTQNALF + AIKP+EV+ RE AAEGKLDLL LDFRMSTTCL Sbjct: 720 GSSGKGHEYFLKYLLGTQNALFSDESAAIKPAEVEVRE-AAEGKLDLLTVLDFRMSTTCL 778 Query: 779 YADIVLPTATWYEKDDLNTSDMHPFIHPLSEAVQPLWESKTDWEIYKGIAKKFSEIGGDY 838 Y DIVLPTATWYEKDDLNTSDMHPFIHPLSEAVQPLWESKTDWEIYK IAKKF+EI G Sbjct: 779 YGDIVLPTATWYEKDDLNTSDMHPFIHPLSEAVQPLWESKTDWEIYKTIAKKFTEIAGPL 838 Query: 839 LGTRSDIVLQPLMHDTPAELGQPFEPKDWKKGECDLIPGKTAPNFVVVERNYKDIYKKFT 898 LGTR D+V PLMHDTP ELGQPF P+DWK GECDLIPGKTAP VVERNY DIY+KFT Sbjct: 839 LGTRRDLVCTPLMHDTPGELGQPFAPRDWKHGECDLIPGKTAPAMTVVERNYADIYRKFT 898 Query: 899 SIGPLLDKLGNGGKGINWQTGHEVGELAALNKRVTEPGVSQGRPRLDSAIDACEMILSFA 958 S+GPLLDKLGNGGKGINW T HEV ELA L +VT PGVSQGRPRL++A DA EMIL+FA Sbjct: 899 SVGPLLDKLGNGGKGINWDTEHEVHELAGLTHKVTTPGVSQGRPRLETATDAAEMILTFA 958 Query: 959 PETNGHVAVKAWEALGKITGRDHTHLAVGREHDKIRFRDVQAQPRKIISAPTWSGLESEE 1018 PETNGHVAVKAW+AL KITGRDHTHLAVGREHDKIRFRDVQAQPRKIISAPTWSGLESEE Sbjct: 959 PETNGHVAVKAWDALSKITGRDHTHLAVGREHDKIRFRDVQAQPRKIISAPTWSGLESEE 1018 Query: 1019 VSYNAGYTNVHELIPWRTLTGRQQFYQDHRWMLDFGEGLCVYKPAVDTKTVAPMLNRQPN 1078 VSYNAGYTNVHELIPWRTLTGRQQFYQDHRWMLDFGEG+C+YKP +DTKTV PML + N Sbjct: 1019 VSYNAGYTNVHELIPWRTLTGRQQFYQDHRWMLDFGEGVCLYKPPIDTKTVQPMLGKHSN 1078 Query: 1079 GEKEIVLNFLTPHQKWGIHSTYSDNLRMLTLSRGGPHVWISEDDAKAAGLVDNDWVEVFN 1138 G E+VLN++TPHQKWGIHSTYSDNLRMLTLSRGGPHVW+SE +AKAAGL DNDWVEVFN Sbjct: 1079 GNPELVLNWITPHQKWGIHSTYSDNLRMLTLSRGGPHVWVSEPEAKAAGLRDNDWVEVFN 1138 Query: 1139 SNGTLTARVVVSQRIPGGMCLMYHAQEKIVNTPGAQLSGKRGGIHNSVTRAVLKPTHMIG 1198 NGTLTAR+VVSQR+P GMCLMYHAQEKIVN PGA+ SG RGGIHNSVTR V KPTHMIG Sbjct: 1139 VNGTLTARLVVSQRVPRGMCLMYHAQEKIVNVPGAETSGMRGGIHNSVTRTVTKPTHMIG 1198 Query: 1199 GYAQLSYGFNYYGTVGSNRDEFIVLRKMNKVDWLDGRKQE 1238 GYAQL+YGFNYYGTVGSNRDEF+++RKM ++DW++ + E Sbjct: 1199 GYAQLAYGFNYYGTVGSNRDEFVIVRKMQRIDWMEEQLAE 1238 >STM1764 [C] COG5013 Nitrate reductase alpha subunit Sty Salmonella typhimurium LT2 Length = 1247 Score = 1768 bits (4578), Expect = 0.0, Method: Compositional matrix adjust. Identities = 824/1253 (65%), Positives = 997/1253 (79%), Gaps = 24/1253 (1%) Query: 1 MSHFLDRLKFMSRVKSTFADGHGAVVNEDRQWENAYRSRWQHDKEVRSTHGVNCTGSCSW 60 MS FLDR ++ + TFADGHG ++ +R WE+ YR RWQHDK VRSTHGVNCTGSCSW Sbjct: 1 MSKFLDRFRYFKQKGETFADGHGQLLETNRDWEDGYRQRWQHDKIVRSTHGVNCTGSCSW 60 Query: 61 KVYVKNGLITWETQQTDYPRTRPDLPNHEPRGCPRGASYSWYVYSAQRVKYPMIRGRLMQ 120 K+YVKNGL+TWETQQTDYPRTRPD+PNHEPRGCPRGASYSWY+YSA R+KYP++R RLM+ Sbjct: 61 KIYVKNGLVTWETQQTDYPRTRPDMPNHEPRGCPRGASYSWYLYSANRLKYPLMRKRLMK 120 Query: 121 LWQEARRT-LSPVEAWAAITSDAAKATSYKSVRGLGGFVRADWDTANEIIAAANAYTIKQ 179 +W+EA++ PVEAWA+I DA KA S+K RG GGFVR+ W NE+IAA+N YT+K Sbjct: 121 MWREAKKLHRDPVEAWASIIEDADKAKSFKQARGRGGFVRSSWQEVNELIAASNVYTVKT 180 Query: 180 YGPDRVIGFSPIPAMSMVSYAAGARYLSLIGGVPLSFYDWYCDLPPASPQIWGEQTDVPE 239 YGPDRV GFSPIPAMSMVSYA+GARYLSLIGG LSFYDWYCDLPPASPQ WGEQTDVPE Sbjct: 181 YGPDRVAGFSPIPAMSMVSYASGARYLSLIGGTCLSFYDWYCDLPPASPQTWGEQTDVPE 240 Query: 240 SADWYNSTYLMVWGSNVPQTRTPDAHFYTEVRYKGTKTVAVSSDFGEMVKFGDIWLAPKQ 299 SADWYNS+Y++ WGSNVPQTRTPDAHF+TEVRYKGTKTVAV+ D+ E+ K D+WLAPKQ Sbjct: 241 SADWYNSSYIIAWGSNVPQTRTPDAHFFTEVRYKGTKTVAVTPDYAEIAKLCDLWLAPKQ 300 Query: 300 GTDAALAMAMGHVVLKEFHQAQPSAYFRSYVKQYTDMPMLVRLVQRDGHYLPDHLLRASQ 359 GTDAA+A+AMGHV+L+EFH P YF YV++YTDMPMLV L +RDG+Y +LRA+ Sbjct: 301 GTDAAMALAMGHVMLREFHLDNPRQYFTDYVRRYTDMPMLVMLEERDGYYAAGRMLRAAD 360 Query: 360 LPDQLEEANNADWKSLAIDASTGQIVAPNGSIGYRWGEGQVNDGAKVGRWNLESRDGHSG 419 L D L + NN +WK++AI+ S G++VAPNGSIG+RWGE G+WNLE RDG +G Sbjct: 361 LVDSLGQENNPEWKTVAIN-SNGEMVAPNGSIGFRWGEK--------GKWNLEQRDGTTG 411 Query: 420 REIDPLLSLVAQHDEVVTVAFNYFGGDDAQ--------PLALRQVPVRHVRLADGSTALV 471 E + LSL+ DE+ V F YFGG+ ++ + L ++P + ++LADGS+ALV Sbjct: 412 AETELQLSLLGSQDEIADVGFPYFGGEGSEYFNHVALDNVLLHKLPAKRLQLADGSSALV 471 Query: 472 ATVHDLMMANYGVDQGLGGE-IARSYDDDVPYTPAWQEKHTGVKRELVIQVAREFAQNAH 530 TV+DL MANYG+++GL E A SYDD YTPAW E+ TGV R +I++AREFA NA Sbjct: 472 TTVYDLTMANYGLERGLNDENCAASYDDTKAYTPAWAEQITGVPRAQIIRIAREFADNAD 531 Query: 531 DTQGKSMVIVGAALNHWYHNDMIYRGIINLLMMCGCIGKSGGGWAHYVGQEKLRPQFGWA 590 T G+SM+IVGA LNHWYH DM YRG+IN+L+ CGC+G+SGGGWAHYVGQEKLRPQ GW Sbjct: 532 KTHGRSMIIVGAGLNHWYHLDMNYRGLINMLVFCGCVGQSGGGWAHYVGQEKLRPQTGWQ 591 Query: 591 PLAFATDWVRPPRQMNGTSFFYAHTSQWRHEKLGIDEIVAPTADKDKLSSMSMIDMNAKS 650 PLAFA DW RP R MN TS+FY H+SQWR+E + +E+++P ADK + S +ID N ++ Sbjct: 592 PLAFALDWQRPARHMNSTSYFYNHSSQWRYETVTAEELLSPMADKSRYSG-HLIDFNVRA 650 Query: 651 ERMGWLPSAPQLETNPLDICDNARAMGQTPQDYLKEALKSGTVNMSCDDPDNPKNFPRNM 710 ERMGWLPSAPQL TNPL I A G TP DY ++LK G++ + + P+N KN PRN+ Sbjct: 651 ERMGWLPSAPQLGTNPLYIAREAEKAGMTPVDYTVKSLKEGSIRFAAEQPENGKNHPRNL 710 Query: 711 FVWRSNILGSSGKGHEYFLKYLLGTQNAL--FD-NPDEAIKPSEVKYREQAAEGKLDLLV 767 F+WRSN+LGSSGKGHEY LKYLLGT++ + D +KP EV++R+ +GKLDL+V Sbjct: 711 FIWRSNLLGSSGKGHEYMLKYLLGTEHGIQGLDLGKQGGVKPEEVEWRDNGLDGKLDLVV 770 Query: 768 TLDFRMSTTCLYADIVLPTATWYEKDDLNTSDMHPFIHPLSEAVQPLWESKTDWEIYKGI 827 TLDFR+S+TCLY+DIVLPTATWYEKDD+NTSDMHPFIHPLS AV P WESK+DWEIYKGI Sbjct: 771 TLDFRLSSTCLYSDIVLPTATWYEKDDMNTSDMHPFIHPLSAAVDPAWESKSDWEIYKGI 830 Query: 828 AKKFSEIGGDYLGTRSDIVLQPLMHDTPAELGQPFEPKDWKKGECDLIPGKTAPNFVVVE 887 AKKFSE+ +LG +D+V P+ HD+ AEL QP + KDWKKGECDLIPGKTAP+ + VE Sbjct: 831 AKKFSEVCVGHLGKETDVVTLPIQHDSAAELAQPLDVKDWKKGECDLIPGKTAPHIMTVE 890 Query: 888 RNYKDIYKKFTSIGPLLDKLGNGGKGINWQTGHEVGELAALNKRVTEPGVSQGRPRLDSA 947 R+Y Y++FTSIGPL++K+GNGGKGI W T E+ L LN + G ++G+P L++A Sbjct: 891 RDYPATYERFTSIGPLMEKIGNGGKGIAWNTQSEMDLLRKLNYTKAD-GPAKGQPMLNTA 949 Query: 948 IDACEMILSFAPETNGHVAVKAWEALGKITGRDHTHLAVGREHDKIRFRDVQAQPRKIIS 1007 IDA EMIL+ APETNG VAVKAW AL + TGRDHTHLA +E +KIRFRD+QAQPRKIIS Sbjct: 950 IDAAEMILTLAPETNGQVAVKAWAALSEFTGRDHTHLATNKEEEKIRFRDIQAQPRKIIS 1009 Query: 1008 APTWSGLESEEVSYNAGYTNVHELIPWRTLTGRQQFYQDHRWMLDFGEGLCVYKPAVDTK 1067 +PTWSGLE E VSYNAGYTNVHELIPWRTL+GRQQ YQDH+WM DFGE L VY+P +DT+ Sbjct: 1010 SPTWSGLEDEHVSYNAGYTNVHELIPWRTLSGRQQLYQDHQWMRDFGESLLVYRPPIDTR 1069 Query: 1068 TVAPMLNRQPNGEKEIVLNFLTPHQKWGIHSTYSDNLRMLTLSRGGPHVWISEDDAKAAG 1127 +V ++ R+ NG E LNFLTPHQKWGIHSTYSDNL MLTLSRGGP VW+SE DAK G Sbjct: 1070 SVKAVMGRKSNGNPEKALNFLTPHQKWGIHSTYSDNLLMLTLSRGGPIVWMSETDAKDLG 1129 Query: 1128 LVDNDWVEVFNSNGTLTARVVVSQRIPGGMCLMYHAQEKIVNTPGAQLSGKRGGIHNSVT 1187 + DNDW+EVFNSNG LTAR VVSQR+P GM +MYHAQE+IVN PG++++ +RGGIHNSVT Sbjct: 1130 IEDNDWIEVFNSNGALTARAVVSQRVPAGMTMMYHAQERIVNLPGSEITQQRGGIHNSVT 1189 Query: 1188 RAVLKPTHMIGGYAQLSYGFNYYGTVGSNRDEFIVLRKMNKVDWLDGRKQERT 1240 R KPTHMIGGYAQL+YGFNYYGTVGSNRDEF+V+RKM ++WLDG ++ Sbjct: 1190 RITPKPTHMIGGYAQLAYGFNYYGTVGSNRDEFVVVRKMKNINWLDGEGNDQV 1242 >narG [C] COG5013 Nitrate reductase alpha subunit Eco Escherichia coli K12 Length = 1247 Score = 1766 bits (4573), Expect = 0.0, Method: Compositional matrix adjust. Identities = 823/1253 (65%), Positives = 995/1253 (79%), Gaps = 24/1253 (1%) Query: 1 MSHFLDRLKFMSRVKSTFADGHGAVVNEDRQWENAYRSRWQHDKEVRSTHGVNCTGSCSW 60 MS FLDR ++ + TFADGHG ++N +R WE+ YR RWQHDK VRSTHGVNCTGSCSW Sbjct: 1 MSKFLDRFRYFKQKGETFADGHGQLLNTNRDWEDGYRQRWQHDKIVRSTHGVNCTGSCSW 60 Query: 61 KVYVKNGLITWETQQTDYPRTRPDLPNHEPRGCPRGASYSWYVYSAQRVKYPMIRGRLMQ 120 K+YVKNGL+TWETQQTDYPRTRPDLPNHEPRGCPRGASYSWY+YSA R+KYPM+R RLM+ Sbjct: 61 KIYVKNGLVTWETQQTDYPRTRPDLPNHEPRGCPRGASYSWYLYSANRLKYPMMRKRLMK 120 Query: 121 LWQEARRTLS-PVEAWAAITSDAAKATSYKSVRGLGGFVRADWDTANEIIAAANAYTIKQ 179 +W+EA+ S PVEAWA+I DA KA S+K RG GGFVR+ W NE+IAA+N YTIK Sbjct: 121 MWREAKALHSDPVEAWASIIEDADKAKSFKQARGRGGFVRSSWQEVNELIAASNVYTIKN 180 Query: 180 YGPDRVIGFSPIPAMSMVSYAAGARYLSLIGGVPLSFYDWYCDLPPASPQIWGEQTDVPE 239 YGPDRV GFSPIPAMSMVSYA+GARYLSLIGG LSFYDWYCDLPPASPQ WGEQTDVPE Sbjct: 181 YGPDRVAGFSPIPAMSMVSYASGARYLSLIGGTCLSFYDWYCDLPPASPQTWGEQTDVPE 240 Query: 240 SADWYNSTYLMVWGSNVPQTRTPDAHFYTEVRYKGTKTVAVSSDFGEMVKFGDIWLAPKQ 299 SADWYNS+Y++ WGSNVPQTRTPDAHF+TEVRYKGTKTVAV+ D+ E+ K D+WLAPKQ Sbjct: 241 SADWYNSSYIIAWGSNVPQTRTPDAHFFTEVRYKGTKTVAVTPDYAEIAKLCDLWLAPKQ 300 Query: 300 GTDAALAMAMGHVVLKEFHQAQPSAYFRSYVKQYTDMPMLVRLVQRDGHYLPDHLLRASQ 359 GTDAA+A+AMGHV+L+EFH PS YF YV++YTDMPMLV L +RDG+Y +LRA+ Sbjct: 301 GTDAAMALAMGHVMLREFHLDNPSQYFTDYVRRYTDMPMLVMLEERDGYYAAGRMLRAAD 360 Query: 360 LPDQLEEANNADWKSLAIDASTGQIVAPNGSIGYRWGEGQVNDGAKVGRWNLESRDGHSG 419 L D L + NN +WK++A + + G++VAPNGSIG+RWGE G+WNLE RDG +G Sbjct: 361 LVDALGQENNPEWKTVAFN-TNGEMVAPNGSIGFRWGEK--------GKWNLEQRDGKTG 411 Query: 420 REIDPLLSLVAQHDEVVTVAFNYFGGD--------DAQPLALRQVPVRHVRLADGSTALV 471 E + LSL+ DE+ V F YFGGD + + + L ++PV+ ++LADGSTALV Sbjct: 412 EETELQLSLLGSQDEIAEVGFPYFGGDGTEHFNKVELENVLLHKLPVKRLQLADGSTALV 471 Query: 472 ATVHDLMMANYGVDQGLGG-EIARSYDDDVPYTPAWQEKHTGVKRELVIQVAREFAQNAH 530 TV+DL +ANYG+++GL A SYDD YTPAW E+ TGV R +I++AREFA NA Sbjct: 472 TTVYDLTLANYGLERGLNDVNCATSYDDVKAYTPAWAEQITGVSRSQIIRIAREFADNAD 531 Query: 531 DTQGKSMVIVGAALNHWYHNDMIYRGIINLLMMCGCIGKSGGGWAHYVGQEKLRPQFGWA 590 T G+SM+IVGA LNHWYH DM YRG+IN+L+ CGC+G+SGGGWAHYVGQEKLRPQ GW Sbjct: 532 KTHGRSMIIVGAGLNHWYHLDMNYRGLINMLIFCGCVGQSGGGWAHYVGQEKLRPQTGWQ 591 Query: 591 PLAFATDWVRPPRQMNGTSFFYAHTSQWRHEKLGIDEIVAPTADKDKLSSMSMIDMNAKS 650 PLAFA DW RP R MN TS+FY H+SQWR+E + +E+++P ADK + + +ID N ++ Sbjct: 592 PLAFALDWQRPARHMNSTSYFYNHSSQWRYETVTAEELLSPMADKSRYTG-HLIDFNVRA 650 Query: 651 ERMGWLPSAPQLETNPLDICDNARAMGQTPQDYLKEALKSGTVNMSCDDPDNPKNFPRNM 710 ERMGWLPSAPQL TNPL I A G P DY ++LK G++ + + P+N KN PRN+ Sbjct: 651 ERMGWLPSAPQLGTNPLTIAGEAEKAGMNPVDYTVKSLKEGSIRFAAEQPENGKNHPRNL 710 Query: 711 FVWRSNILGSSGKGHEYFLKYLLGTQNALFDN---PDEAIKPSEVKYREQAAEGKLDLLV 767 F+WRSN+LGSSGKGHE+ LKYLLGT++ + +KP EV +++ EGKLDL+V Sbjct: 711 FIWRSNLLGSSGKGHEFMLKYLLGTEHGIQGKDLGQQGGVKPEEVDWQDNGLEGKLDLVV 770 Query: 768 TLDFRMSTTCLYADIVLPTATWYEKDDLNTSDMHPFIHPLSEAVQPLWESKTDWEIYKGI 827 TLDFR+S+TCLY+DI+LPTATWYEKDD+NTSDMHPFIHPLS AV P WE+K+DWEIYK I Sbjct: 771 TLDFRLSSTCLYSDIILPTATWYEKDDMNTSDMHPFIHPLSAAVDPAWEAKSDWEIYKAI 830 Query: 828 AKKFSEIGGDYLGTRSDIVLQPLMHDTPAELGQPFEPKDWKKGECDLIPGKTAPNFVVVE 887 AKKFSE+ +LG +DIV P+ HD+ AEL QP + KDWKKGECDLIPGKTAP+ +VVE Sbjct: 831 AKKFSEVCVGHLGKETDIVTLPIQHDSAAELAQPLDVKDWKKGECDLIPGKTAPHIMVVE 890 Query: 888 RNYKDIYKKFTSIGPLLDKLGNGGKGINWQTGHEVGELAALNKRVTEPGVSQGRPRLDSA 947 R+Y Y++FTSIGPL++K+GNGGKGI W T E+ L LN E G ++G+P L++A Sbjct: 891 RDYPATYERFTSIGPLMEKIGNGGKGIAWNTQSEMDLLRKLNYTKAE-GPAKGQPMLNTA 949 Query: 948 IDACEMILSFAPETNGHVAVKAWEALGKITGRDHTHLAVGREHDKIRFRDVQAQPRKIIS 1007 IDA EMIL+ APETNG VAVKAW AL + TGRDHTHLA+ +E +KIRFRD+QAQPRKIIS Sbjct: 950 IDAAEMILTLAPETNGQVAVKAWAALSEFTGRDHTHLALNKEDEKIRFRDIQAQPRKIIS 1009 Query: 1008 APTWSGLESEEVSYNAGYTNVHELIPWRTLTGRQQFYQDHRWMLDFGEGLCVYKPAVDTK 1067 +PTWSGLE E VSYNAGYTNVHELIPWRTL+GRQQ YQDH+WM DFGE L VY+P +DT+ Sbjct: 1010 SPTWSGLEDEHVSYNAGYTNVHELIPWRTLSGRQQLYQDHQWMRDFGESLLVYRPPIDTR 1069 Query: 1068 TVAPMLNRQPNGEKEIVLNFLTPHQKWGIHSTYSDNLRMLTLSRGGPHVWISEDDAKAAG 1127 +V ++ ++ NG +E LNFLTPHQKWGIHSTYSDNL MLTL RGGP VW+SE DAK G Sbjct: 1070 SVKEVIGQKSNGNQEKALNFLTPHQKWGIHSTYSDNLLMLTLGRGGPVVWLSEADAKDLG 1129 Query: 1128 LVDNDWVEVFNSNGTLTARVVVSQRIPGGMCLMYHAQEKIVNTPGAQLSGKRGGIHNSVT 1187 + DNDW+EVFNSNG LTAR VVSQR+P GM +MYHAQE+IVN PG++++ +RGGIHNSVT Sbjct: 1130 IADNDWIEVFNSNGALTARAVVSQRVPAGMTMMYHAQERIVNLPGSEITQQRGGIHNSVT 1189 Query: 1188 RAVLKPTHMIGGYAQLSYGFNYYGTVGSNRDEFIVLRKMNKVDWLDGRKQERT 1240 R KPTHMIGGYA L+YGFNYYGTVGSNRDEF+V+RKM +DWLDG ++ Sbjct: 1190 RITPKPTHMIGGYAHLAYGFNYYGTVGSNRDEFVVVRKMKNIDWLDGEGNDQV 1242 >ZnarG [C] COG5013 Nitrate reductase alpha subunit EcZ Escherichia coli O157:H7 EDL933 Length = 1247 Score = 1765 bits (4572), Expect = 0.0, Method: Compositional matrix adjust. Identities = 823/1253 (65%), Positives = 994/1253 (79%), Gaps = 24/1253 (1%) Query: 1 MSHFLDRLKFMSRVKSTFADGHGAVVNEDRQWENAYRSRWQHDKEVRSTHGVNCTGSCSW 60 MS FLDR ++ + TFADGHG ++N +R WE+ YR RWQHDK VRSTHGVNCTGSCSW Sbjct: 1 MSKFLDRFRYFKQKGETFADGHGQLLNTNRDWEDGYRQRWQHDKIVRSTHGVNCTGSCSW 60 Query: 61 KVYVKNGLITWETQQTDYPRTRPDLPNHEPRGCPRGASYSWYVYSAQRVKYPMIRGRLMQ 120 K+YVKNGL+TWETQQTDYPRTRPDLPNHEPRGCPRGASYSWY+YSA R+KYPM+R RLM+ Sbjct: 61 KIYVKNGLVTWETQQTDYPRTRPDLPNHEPRGCPRGASYSWYLYSANRLKYPMMRKRLMK 120 Query: 121 LWQEARRTLS-PVEAWAAITSDAAKATSYKSVRGLGGFVRADWDTANEIIAAANAYTIKQ 179 +W+EA+ S PVEAWA+I DA KA S+K RG GGFVR+ W NE+IAA+N YTIK Sbjct: 121 MWREAKALHSDPVEAWASIIEDADKAKSFKQARGRGGFVRSSWQEVNELIAASNVYTIKN 180 Query: 180 YGPDRVIGFSPIPAMSMVSYAAGARYLSLIGGVPLSFYDWYCDLPPASPQIWGEQTDVPE 239 YGPDRV GFSPIPAMSMVSYA+GARYLSLIGG LSFYDWYCDLPPASPQ WGEQTDVPE Sbjct: 181 YGPDRVAGFSPIPAMSMVSYASGARYLSLIGGTCLSFYDWYCDLPPASPQTWGEQTDVPE 240 Query: 240 SADWYNSTYLMVWGSNVPQTRTPDAHFYTEVRYKGTKTVAVSSDFGEMVKFGDIWLAPKQ 299 SADWYNS+Y++ WGSNVPQTRTPDAHF+TEVRYKGTKTVAV+ D+ E+ K D+WLAPKQ Sbjct: 241 SADWYNSSYIIAWGSNVPQTRTPDAHFFTEVRYKGTKTVAVTPDYAEIAKLCDLWLAPKQ 300 Query: 300 GTDAALAMAMGHVVLKEFHQAQPSAYFRSYVKQYTDMPMLVRLVQRDGHYLPDHLLRASQ 359 GTDAA+A+AMGHV+L+EFH PS YF YV++YTDMPMLV L +RDG+Y +LRA+ Sbjct: 301 GTDAAMALAMGHVMLREFHLDNPSQYFTDYVRRYTDMPMLVMLEERDGYYAAGRMLRAAD 360 Query: 360 LPDQLEEANNADWKSLAIDASTGQIVAPNGSIGYRWGEGQVNDGAKVGRWNLESRDGHSG 419 L D L + NN +WK++A + + G++VAPNGSIG+RWGE G+WNLE RDG +G Sbjct: 361 LVDALGQENNPEWKTVAFN-TNGEMVAPNGSIGFRWGEK--------GKWNLEQRDGKTG 411 Query: 420 REIDPLLSLVAQHDEVVTVAFNYFGGD--------DAQPLALRQVPVRHVRLADGSTALV 471 E + LSL+ DE+ V F YFGGD + + + L ++PV+ ++LADGSTALV Sbjct: 412 EETELQLSLLGSQDEIAEVGFPYFGGDGTEHFNKVELENVLLHKLPVKRLQLADGSTALV 471 Query: 472 ATVHDLMMANYGVDQGLGG-EIARSYDDDVPYTPAWQEKHTGVKRELVIQVAREFAQNAH 530 TV+DL +ANYG+++GL A SYDD YTPAW E+ TGV R +I++AREFA NA Sbjct: 472 TTVYDLTLANYGLERGLNDVNCATSYDDVKAYTPAWAEQITGVSRSQIIRIAREFADNAD 531 Query: 531 DTQGKSMVIVGAALNHWYHNDMIYRGIINLLMMCGCIGKSGGGWAHYVGQEKLRPQFGWA 590 T G+SM+IVGA LNHWYH DM YRG+IN+L+ CGC+G+SGGGWAHYVGQEKLRPQ GW Sbjct: 532 KTHGRSMIIVGAGLNHWYHLDMNYRGLINMLIFCGCVGQSGGGWAHYVGQEKLRPQTGWQ 591 Query: 591 PLAFATDWVRPPRQMNGTSFFYAHTSQWRHEKLGIDEIVAPTADKDKLSSMSMIDMNAKS 650 PLAFA DW RP R MN TS+FY H+SQWR+E + +E+++P ADK + + +ID N ++ Sbjct: 592 PLAFALDWQRPARHMNSTSYFYNHSSQWRYETVTAEELLSPMADKSRYTG-HLIDFNVRA 650 Query: 651 ERMGWLPSAPQLETNPLDICDNARAMGQTPQDYLKEALKSGTVNMSCDDPDNPKNFPRNM 710 ERMGWLPSAPQL TNPL I A G P DY ++LK G++ + + P+N KN PRN+ Sbjct: 651 ERMGWLPSAPQLGTNPLTIAGEAEKAGMNPVDYTVKSLKEGSIRFAAEQPENGKNHPRNL 710 Query: 711 FVWRSNILGSSGKGHEYFLKYLLGTQNALFDN---PDEAIKPSEVKYREQAAEGKLDLLV 767 F+WRSN+LGSSGKGHE+ LKYLLGT++ + +KP EV +++ EGKLDL+V Sbjct: 711 FIWRSNLLGSSGKGHEFMLKYLLGTEHGIQGKDLGQQGGVKPEEVDWQDNGLEGKLDLVV 770 Query: 768 TLDFRMSTTCLYADIVLPTATWYEKDDLNTSDMHPFIHPLSEAVQPLWESKTDWEIYKGI 827 TLDFR+S+TCLY+DI+LPTATWYEKDD+NTSDMHPFIHPLS AV P WE+K+DWEIYK I Sbjct: 771 TLDFRLSSTCLYSDIILPTATWYEKDDMNTSDMHPFIHPLSAAVDPAWEAKSDWEIYKAI 830 Query: 828 AKKFSEIGGDYLGTRSDIVLQPLMHDTPAELGQPFEPKDWKKGECDLIPGKTAPNFVVVE 887 AKKFSE+ +LG +DIV P+ HD+ AEL QP + KDWKKGECDLIPGKTAP+ +VVE Sbjct: 831 AKKFSEVCVGHLGKETDIVTLPIQHDSAAELAQPLDVKDWKKGECDLIPGKTAPHIMVVE 890 Query: 888 RNYKDIYKKFTSIGPLLDKLGNGGKGINWQTGHEVGELAALNKRVTEPGVSQGRPRLDSA 947 R+Y Y++FTSIGPL++K+GNGGKGI W T E+ L LN E G ++G+P L++A Sbjct: 891 RDYPATYERFTSIGPLMEKIGNGGKGIAWNTQSEMDLLRKLNYTKAE-GPAKGQPMLNTA 949 Query: 948 IDACEMILSFAPETNGHVAVKAWEALGKITGRDHTHLAVGREHDKIRFRDVQAQPRKIIS 1007 IDA EMIL+ APETNG VAVKAW AL + TGRDHTHLA+ +E +KIRFRD+QAQPRKIIS Sbjct: 950 IDAAEMILTLAPETNGQVAVKAWAALSEFTGRDHTHLALNKEDEKIRFRDIQAQPRKIIS 1009 Query: 1008 APTWSGLESEEVSYNAGYTNVHELIPWRTLTGRQQFYQDHRWMLDFGEGLCVYKPAVDTK 1067 +PTWSGLE E VSYNAGYTNVHELIPWRTL+GRQQ YQDH+WM DFGE L VY+P +DT+ Sbjct: 1010 SPTWSGLEDEHVSYNAGYTNVHELIPWRTLSGRQQLYQDHQWMRDFGESLLVYRPPIDTR 1069 Query: 1068 TVAPMLNRQPNGEKEIVLNFLTPHQKWGIHSTYSDNLRMLTLSRGGPHVWISEDDAKAAG 1127 +V ++ ++ NG E LNFLTPHQKWGIHSTYSDNL MLTL RGGP VW+SE DAK G Sbjct: 1070 SVKEVIGQKSNGNPEKALNFLTPHQKWGIHSTYSDNLLMLTLGRGGPVVWLSEADAKDLG 1129 Query: 1128 LVDNDWVEVFNSNGTLTARVVVSQRIPGGMCLMYHAQEKIVNTPGAQLSGKRGGIHNSVT 1187 + DNDW+EVFNSNG LTAR VVSQR+P GM +MYHAQE+IVN PG++++ +RGGIHNSVT Sbjct: 1130 IADNDWIEVFNSNGALTARAVVSQRVPAGMTMMYHAQERIVNLPGSEITQQRGGIHNSVT 1189 Query: 1188 RAVLKPTHMIGGYAQLSYGFNYYGTVGSNRDEFIVLRKMNKVDWLDGRKQERT 1240 R KPTHMIGGYA L+YGFNYYGTVGSNRDEF+V+RKM +DWLDG ++ Sbjct: 1190 RITPKPTHMIGGYAHLAYGFNYYGTVGSNRDEFVVVRKMKNIDWLDGEGNDQV 1242 >ECs1729 [C] COG5013 Nitrate reductase alpha subunit Ecs Escherichia coli O157:H7 Length = 1247 Score = 1765 bits (4572), Expect = 0.0, Method: Compositional matrix adjust. Identities = 823/1253 (65%), Positives = 994/1253 (79%), Gaps = 24/1253 (1%) Query: 1 MSHFLDRLKFMSRVKSTFADGHGAVVNEDRQWENAYRSRWQHDKEVRSTHGVNCTGSCSW 60 MS FLDR ++ + TFADGHG ++N +R WE+ YR RWQHDK VRSTHGVNCTGSCSW Sbjct: 1 MSKFLDRFRYFKQKGETFADGHGQLLNTNRDWEDGYRQRWQHDKIVRSTHGVNCTGSCSW 60 Query: 61 KVYVKNGLITWETQQTDYPRTRPDLPNHEPRGCPRGASYSWYVYSAQRVKYPMIRGRLMQ 120 K+YVKNGL+TWETQQTDYPRTRPDLPNHEPRGCPRGASYSWY+YSA R+KYPM+R RLM+ Sbjct: 61 KIYVKNGLVTWETQQTDYPRTRPDLPNHEPRGCPRGASYSWYLYSANRLKYPMMRKRLMK 120 Query: 121 LWQEARRTLS-PVEAWAAITSDAAKATSYKSVRGLGGFVRADWDTANEIIAAANAYTIKQ 179 +W+EA+ S PVEAWA+I DA KA S+K RG GGFVR+ W NE+IAA+N YTIK Sbjct: 121 MWREAKALHSDPVEAWASIIEDADKAKSFKQARGRGGFVRSSWQEVNELIAASNVYTIKN 180 Query: 180 YGPDRVIGFSPIPAMSMVSYAAGARYLSLIGGVPLSFYDWYCDLPPASPQIWGEQTDVPE 239 YGPDRV GFSPIPAMSMVSYA+GARYLSLIGG LSFYDWYCDLPPASPQ WGEQTDVPE Sbjct: 181 YGPDRVAGFSPIPAMSMVSYASGARYLSLIGGTCLSFYDWYCDLPPASPQTWGEQTDVPE 240 Query: 240 SADWYNSTYLMVWGSNVPQTRTPDAHFYTEVRYKGTKTVAVSSDFGEMVKFGDIWLAPKQ 299 SADWYNS+Y++ WGSNVPQTRTPDAHF+TEVRYKGTKTVAV+ D+ E+ K D+WLAPKQ Sbjct: 241 SADWYNSSYIIAWGSNVPQTRTPDAHFFTEVRYKGTKTVAVTPDYAEIAKLCDLWLAPKQ 300 Query: 300 GTDAALAMAMGHVVLKEFHQAQPSAYFRSYVKQYTDMPMLVRLVQRDGHYLPDHLLRASQ 359 GTDAA+A+AMGHV+L+EFH PS YF YV++YTDMPMLV L +RDG+Y +LRA+ Sbjct: 301 GTDAAMALAMGHVMLREFHLDNPSQYFTDYVRRYTDMPMLVMLEERDGYYAAGRMLRAAD 360 Query: 360 LPDQLEEANNADWKSLAIDASTGQIVAPNGSIGYRWGEGQVNDGAKVGRWNLESRDGHSG 419 L D L + NN +WK++A + + G++VAPNGSIG+RWGE G+WNLE RDG +G Sbjct: 361 LVDALGQENNPEWKTVAFN-TNGEMVAPNGSIGFRWGEK--------GKWNLEQRDGKTG 411 Query: 420 REIDPLLSLVAQHDEVVTVAFNYFGGD--------DAQPLALRQVPVRHVRLADGSTALV 471 E + LSL+ DE+ V F YFGGD + + + L ++PV+ ++LADGSTALV Sbjct: 412 EETELQLSLLGSQDEIAEVGFPYFGGDGTEHFNKVELENVLLHKLPVKRLQLADGSTALV 471 Query: 472 ATVHDLMMANYGVDQGLGG-EIARSYDDDVPYTPAWQEKHTGVKRELVIQVAREFAQNAH 530 TV+DL +ANYG+++GL A SYDD YTPAW E+ TGV R +I++AREFA NA Sbjct: 472 TTVYDLTLANYGLERGLNDVNCATSYDDVKAYTPAWAEQITGVSRSQIIRIAREFADNAD 531 Query: 531 DTQGKSMVIVGAALNHWYHNDMIYRGIINLLMMCGCIGKSGGGWAHYVGQEKLRPQFGWA 590 T G+SM+IVGA LNHWYH DM YRG+IN+L+ CGC+G+SGGGWAHYVGQEKLRPQ GW Sbjct: 532 KTHGRSMIIVGAGLNHWYHLDMNYRGLINMLIFCGCVGQSGGGWAHYVGQEKLRPQTGWQ 591 Query: 591 PLAFATDWVRPPRQMNGTSFFYAHTSQWRHEKLGIDEIVAPTADKDKLSSMSMIDMNAKS 650 PLAFA DW RP R MN TS+FY H+SQWR+E + +E+++P ADK + + +ID N ++ Sbjct: 592 PLAFALDWQRPARHMNSTSYFYNHSSQWRYETVTAEELLSPMADKSRYTG-HLIDFNVRA 650 Query: 651 ERMGWLPSAPQLETNPLDICDNARAMGQTPQDYLKEALKSGTVNMSCDDPDNPKNFPRNM 710 ERMGWLPSAPQL TNPL I A G P DY ++LK G++ + + P+N KN PRN+ Sbjct: 651 ERMGWLPSAPQLGTNPLTIAGEAEKAGMNPVDYTVKSLKEGSIRFAAEQPENGKNHPRNL 710 Query: 711 FVWRSNILGSSGKGHEYFLKYLLGTQNALFDN---PDEAIKPSEVKYREQAAEGKLDLLV 767 F+WRSN+LGSSGKGHE+ LKYLLGT++ + +KP EV +++ EGKLDL+V Sbjct: 711 FIWRSNLLGSSGKGHEFMLKYLLGTEHGIQGKDLGQQGGVKPEEVDWQDNGLEGKLDLVV 770 Query: 768 TLDFRMSTTCLYADIVLPTATWYEKDDLNTSDMHPFIHPLSEAVQPLWESKTDWEIYKGI 827 TLDFR+S+TCLY+DI+LPTATWYEKDD+NTSDMHPFIHPLS AV P WE+K+DWEIYK I Sbjct: 771 TLDFRLSSTCLYSDIILPTATWYEKDDMNTSDMHPFIHPLSAAVDPAWEAKSDWEIYKAI 830 Query: 828 AKKFSEIGGDYLGTRSDIVLQPLMHDTPAELGQPFEPKDWKKGECDLIPGKTAPNFVVVE 887 AKKFSE+ +LG +DIV P+ HD+ AEL QP + KDWKKGECDLIPGKTAP+ +VVE Sbjct: 831 AKKFSEVCVGHLGKETDIVTLPIQHDSAAELAQPLDVKDWKKGECDLIPGKTAPHIMVVE 890 Query: 888 RNYKDIYKKFTSIGPLLDKLGNGGKGINWQTGHEVGELAALNKRVTEPGVSQGRPRLDSA 947 R+Y Y++FTSIGPL++K+GNGGKGI W T E+ L LN E G ++G+P L++A Sbjct: 891 RDYPATYERFTSIGPLMEKIGNGGKGIAWNTQSEMDLLRKLNYTKAE-GPAKGQPMLNTA 949 Query: 948 IDACEMILSFAPETNGHVAVKAWEALGKITGRDHTHLAVGREHDKIRFRDVQAQPRKIIS 1007 IDA EMIL+ APETNG VAVKAW AL + TGRDHTHLA+ +E +KIRFRD+QAQPRKIIS Sbjct: 950 IDAAEMILTLAPETNGQVAVKAWAALSEFTGRDHTHLALNKEDEKIRFRDIQAQPRKIIS 1009 Query: 1008 APTWSGLESEEVSYNAGYTNVHELIPWRTLTGRQQFYQDHRWMLDFGEGLCVYKPAVDTK 1067 +PTWSGLE E VSYNAGYTNVHELIPWRTL+GRQQ YQDH+WM DFGE L VY+P +DT+ Sbjct: 1010 SPTWSGLEDEHVSYNAGYTNVHELIPWRTLSGRQQLYQDHQWMRDFGESLLVYRPPIDTR 1069 Query: 1068 TVAPMLNRQPNGEKEIVLNFLTPHQKWGIHSTYSDNLRMLTLSRGGPHVWISEDDAKAAG 1127 +V ++ ++ NG E LNFLTPHQKWGIHSTYSDNL MLTL RGGP VW+SE DAK G Sbjct: 1070 SVKEVIGQKSNGNPEKALNFLTPHQKWGIHSTYSDNLLMLTLGRGGPVVWLSEADAKDLG 1129 Query: 1128 LVDNDWVEVFNSNGTLTARVVVSQRIPGGMCLMYHAQEKIVNTPGAQLSGKRGGIHNSVT 1187 + DNDW+EVFNSNG LTAR VVSQR+P GM +MYHAQE+IVN PG++++ +RGGIHNSVT Sbjct: 1130 IADNDWIEVFNSNGALTARAVVSQRVPAGMTMMYHAQERIVNLPGSEITQQRGGIHNSVT 1189 Query: 1188 RAVLKPTHMIGGYAQLSYGFNYYGTVGSNRDEFIVLRKMNKVDWLDGRKQERT 1240 R KPTHMIGGYA L+YGFNYYGTVGSNRDEF+V+RKM +DWLDG ++ Sbjct: 1190 RITPKPTHMIGGYAHLAYGFNYYGTVGSNRDEFVVVRKMKNIDWLDGEGNDQV 1242