BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.3529.p (318 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1285 [K] COG1386 Predicted transcriptional regulator containi... 271 1e-72 XF2452_1 [K] COG1386 Predicted transcriptional regulator contain... 164 2e-40 NMA0951 [K] COG1386 Predicted transcriptional regulator containi... 161 2e-39 PA3197 [K] COG1386 Predicted transcriptional regulator containin... 155 9e-38 CAC2060 [K] COG1386 Predicted transcriptional regulator containi... 105 1e-22 >RSc1285 [K] COG1386 Predicted transcriptional regulator containing the HTH domain Rso Ralstonia solanacearum Length = 304 Score = 271 bits (693), Expect = 1e-72, Method: Compositional matrix adjust. Identities = 128/202 (63%), Positives = 161/202 (79%), Gaps = 11/202 (5%) Query: 1 MNIAEAKKVLETALLCTHEPLSINDLKKLYVDPESQESSDINTETIRQMLEELRADWADK 60 MN EAK VLETAL+C +PL ++DL+KL+ D++ +TIR +LEELR DW D+ Sbjct: 1 MNTQEAKIVLETALICAQDPLRVSDLRKLF-------DEDVSADTIRVLLEELRQDWLDR 53 Query: 61 GVEVVSLSTGWRFQSRKEMKVYLERLNPEKPPKYTRATLETLAIIAYRQPVTRGDIEEIR 120 GVE+V+L++GWR QSR EM+ YL+RL+PEKPPKY+RA +ETLAIIAYRQPVTRGDIE+IR Sbjct: 54 GVELVALASGWRLQSRPEMRAYLDRLHPEKPPKYSRAVMETLAIIAYRQPVTRGDIEDIR 113 Query: 121 GVAVNTQTIRMLEDRGWIESIGHRDVPGRPALFATTRKFLDDLGLSSLEELPPLQQVSGE 180 GV VNTQ I+ +EDRGW+E IGHRDVPGRPAL+ATT++FLDDLGL SL+ELPPL+ Sbjct: 114 GVTVNTQVIKQIEDRGWVEVIGHRDVPGRPALYATTKQFLDDLGLRSLDELPPLE--DAR 171 Query: 181 AAAQGALLELQAL--EGGVAAL 200 A AQ +LLE A+ EGG ++ Sbjct: 172 AQAQASLLEQGAIEFEGGTVSV 193 >XF2452_1 [K] COG1386 Predicted transcriptional regulator containing the HTH domain Xfa Xylella fastidiosa 9a5c Length = 193 Score = 164 bits (415), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 79/174 (45%), Positives = 123/174 (70%), Gaps = 5/174 (2%) Query: 1 MNIAEAKKVLETALLCTHEPLSINDLKKLYVDPESQESSDINTETIRQMLEELRADWADK 60 +++ +++E ALL +++PL++ L+ L+ + I ++I++ +E L+ A++ Sbjct: 10 LDLTLIARIVEGALLASNQPLTLAQLQGLFPN-----DPPIPPDSIQRAIELLQHTCAER 64 Query: 61 GVEVVSLSTGWRFQSRKEMKVYLERLNPEKPPKYTRATLETLAIIAYRQPVTRGDIEEIR 120 VE+V +++G+RFQ + ++ ++ L E+ KY+RATLETLA+IAYRQP+TRG+IE+IR Sbjct: 65 SVELVEVASGFRFQLKADVHAWVTPLWTERKTKYSRATLETLALIAYRQPITRGEIEQIR 124 Query: 121 GVAVNTQTIRMLEDRGWIESIGHRDVPGRPALFATTRKFLDDLGLSSLEELPPL 174 GVAVN+ I LE+R WI +GHRD PG+PALF TT+ FLD GL L+ELPPL Sbjct: 125 GVAVNSNIIHTLEEREWIRVVGHRDAPGKPALFGTTKAFLDYFGLKRLDELPPL 178 >NMA0951 [K] COG1386 Predicted transcriptional regulator containing the HTH domain NmA Neisseria meningitidis Z2491 Length = 200 Score = 161 bits (407), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 83/169 (49%), Positives = 112/169 (66%), Gaps = 7/169 (4%) Query: 9 VLETALLCTHEPLSINDLKKLYVDPESQESSDINTETIRQMLEELRADWADKGVEVVSLS 68 ++E ALL EPL+ +++L V P SQ+ + +L +L+ W D+ +++V Sbjct: 10 LIEAALLTQTEPLTEKSMRELCVPPLSQDK-------LIDVLAQLKTRWQDRALQLVHTQ 62 Query: 69 TGWRFQSRKEMKVYLERLNPEKPPKYTRATLETLAIIAYRQPVTRGDIEEIRGVAVNTQT 128 GWRFQ + L L ++ P+Y+RA +ETLAIIAY+QPVTRGDIE IRGVAV+ Sbjct: 63 EGWRFQIVQTAFERLGSLQEQRAPRYSRAVMETLAIIAYQQPVTRGDIEGIRGVAVSQNV 122 Query: 129 IRMLEDRGWIESIGHRDVPGRPALFATTRKFLDDLGLSSLEELPPLQQV 177 I+ L+DRGWIE IGHRD G+PAL+ATT FL DL L LEELPPL ++ Sbjct: 123 IQTLQDRGWIEVIGHRDTLGKPALWATTATFLSDLRLDGLEELPPLTEL 171 >PA3197 [K] COG1386 Predicted transcriptional regulator containing the HTH domain Pae Pseudomonas aeruginosa Length = 332 Score = 155 bits (393), Expect = 9e-38, Method: Compositional matrix adjust. Identities = 81/180 (45%), Positives = 114/180 (63%), Gaps = 8/180 (4%) Query: 1 MNIA---EAKKVLETALLCTHEPLSINDLKKLYVDPESQESSDINTETIRQMLEELRADW 57 MN++ E +LE LL +PLS+ L +L+ + E E R L L Sbjct: 1 MNLSDPHELATLLEGILLAAGKPLSLERLAELFDEAERPEPG-----QFRDALAILALSC 55 Query: 58 ADKGVEVVSLSTGWRFQSRKEMKVYLERLNPEKPPKYTRATLETLAIIAYRQPVTRGDIE 117 A + E+ +++G+R Q R+ ++ RL E+P +Y+RA LETL +IAYRQP+TRG+IE Sbjct: 56 AGRSFELKEVASGYRLQIRERFSPWVGRLWEERPQRYSRALLETLVLIAYRQPITRGEIE 115 Query: 118 EIRGVAVNTQTIRMLEDRGWIESIGHRDVPGRPALFATTRKFLDDLGLSSLEELPPLQQV 177 EIRGVAVNTQ ++ L +R WI +G+R+VPGRPA+ ATT+ FLD L SL+ELPPL + Sbjct: 116 EIRGVAVNTQIVKTLMEREWIRIVGYREVPGRPAMLATTKAFLDYFNLKSLDELPPLSAL 175 >CAC2060 [K] COG1386 Predicted transcriptional regulator containing the HTH domain Cac Clostridium acetobutylicum Length = 202 Score = 105 bits (262), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 55/175 (31%), Positives = 105/175 (60%), Gaps = 13/175 (7%) Query: 9 VLETALLCTHEPLSINDLKKLYVDPESQESSDINTETIRQMLEELRADWAD--KGVEVVS 66 ++E+ L + EPL + + + + T+ +++L + + D +GV++++ Sbjct: 23 IIESLLFVSGEPLKLKQISAIL---------ECTTKRAQEVLNNMMLKYNDNCRGVKLIN 73 Query: 67 LSTGWRFQSRKEMKVYLERLNPEKPPK-YTRATLETLAIIAYRQPVTRGDIEEIRGVAVN 125 ++ ++ ++ E Y+ +L + ++A LETLAIIAY+QP+TR D++EIRGV + Sbjct: 74 INDSYQLVTKNENSDYVRKLLKTNTRQALSQAALETLAIIAYKQPITRIDVDEIRGVK-S 132 Query: 126 TQTIRMLEDRGWIESIGHRDVPGRPALFATTRKFLDDLGLSSLEELPPLQQVSGE 180 + I L+++ I+ G DVPGRP L+ TT +FL + L +++ELPP++Q++ E Sbjct: 133 DRAILTLQEKKLIQECGRLDVPGRPILYETTDEFLKNFNLGNIDELPPMEQIASE 187