BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.3477.p (1152 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2205 [L] COG0587 DNA polymerase III, alpha subunit Rso Ralsto... 1514 0.0 NMB1827 [L] COG0587 DNA polymerase III, alpha subunit Nme Neisse... 1139 0.0 NMA0632 [L] COG0587 DNA polymerase III, alpha subunit NmA Neisse... 1130 0.0 PA3640 [L] COG0587 DNA polymerase III, alpha subunit Pae Pseudom... 1108 0.0 ZdnaE [L] COG0587 DNA polymerase III, alpha subunit EcZ Escheric... 1060 0.0 >RSc2205 [L] COG0587 DNA polymerase III, alpha subunit Rso Ralstonia solanacearum Length = 1173 Score = 1514 bits (3919), Expect = 0.0, Method: Compositional matrix adjust. Identities = 766/1178 (65%), Positives = 911/1178 (77%), Gaps = 32/1178 (2%) Query: 1 MTTPQFVHLRMHSEYSIVDGLVRIDDIVKAAAKDGQAALAVTDLANLFCMVRFYKEARGK 60 M +P+FVHLR+HSEYS+VDG VR+D+ VKAAA DG ALA+TDLAN F +VRFYKEARGK Sbjct: 1 MNSPRFVHLRLHSEYSVVDGNVRLDEAVKAAAADGMGALALTDLANAFGLVRFYKEARGK 60 Query: 61 GVKPIAGCDLWITNDADREKPFRLLVLIKNRHGYLQLCEVLSQAWLNNQYKGRAEVRMEW 120 GVKPI G D+WITN +R+KP RLL+L++N+ GYL LC +L++AWL+NQ++GRAEV EW Sbjct: 61 GVKPIVGADVWITNHDERDKPSRLLLLVRNKQGYLNLCMLLARAWLSNQHRGRAEVAPEW 120 Query: 121 LEALRHQEG--GNGLIALSGAAMGDIGQAIDNGNLTQAEACARRWAEIFPGAFYLELQRA 178 +E GL+ALSGA GDIG A+ NGN A A +W+++FP +FY+ELQRA Sbjct: 121 FGEPGVEEAPMATGLLALSGAMGGDIGMALANGNEALARKLATQWSQVFPASFYIELQRA 180 Query: 179 GQANMELQVRQSVALGAKLGLPCVATHPIQFQSPEEFIAHEARTCIAEGEIMANARRVRR 238 G A E V+Q+V L A + LP VATHP+QF +P++F AHEAR CIAEG+++AN RR RR Sbjct: 181 GNAGTEAYVQQAVKLAASMQLPVVATHPVQFMTPDDFTAHEARVCIAEGDLLANPRRTRR 240 Query: 239 FNEQQYFKSQAEMAELFADLPGALANSVEIAKRCNLVLQLGKPQLPDFPTPDGMSIDDFL 298 F QYFK+Q EM LFAD+P ALAN+ +IA+RCNL L+LGKP+LP FPTPDGMS+DD+L Sbjct: 241 FTTDQYFKTQDEMCALFADIPSALANTAQIAQRCNLTLELGKPKLPLFPTPDGMSLDDYL 300 Query: 299 VAQTKAGLEVRLKELFPNEAEREKQRPRYEARLEFENNTIIKMKFPGYFLIVADFIQWAK 358 V K GLE R+ LFP+EA RE +RP Y ARLEFE TIIKM FPGYFLIVADFI WAK Sbjct: 301 VHLAKDGLEKRMAVLFPDEAVREAKRPEYYARLEFETGTIIKMGFPGYFLIVADFINWAK 360 Query: 359 NNGVPVGPGRGSGAGSLVAYCLLITDLDPLRYNLLFERFLNPERVSMPDFDIDFCQEGRD 418 NNGVPVGPGRGSGAGSLVAY L ITDLDPL+YNLLFERFLNPERVSMPDFDIDFCQ GRD Sbjct: 361 NNGVPVGPGRGSGAGSLVAYALGITDLDPLKYNLLFERFLNPERVSMPDFDIDFCQHGRD 420 Query: 419 RVIQYVKDRYGKDAVSQIATFGTMAAKGAVRDVGRVLDLGYNFCDGISKLIPFKPGKLVT 478 RVI YVK++YGKDAVSQIATFGTMAAK AVRDVGRVLDLGYNF DG++KLIPFKPGKLVT Sbjct: 421 RVIHYVKEKYGKDAVSQIATFGTMAAKAAVRDVGRVLDLGYNFVDGVAKLIPFKPGKLVT 480 Query: 479 LADAIEEEPLLKERLENEEEVKQLMGLAQQVEGIARNIGMHAGGVLIAPGKLTDFCPLYT 538 + +A +EEPLL ER NEEEVKQL+ LAQ+VEG+ RN+GMHAGGVLIAPGKLTDFCPLYT Sbjct: 481 IEEAKKEEPLLAEREANEEEVKQLLELAQRVEGMTRNVGMHAGGVLIAPGKLTDFCPLYT 540 Query: 539 QGG-DSGVVSQYDKDDVEAVGLVKFDFLGLTTLTILDRAVRYIRMLDPAMADFDLAKLPL 597 QGG D+GVVSQYDKDDVEAVGLVKFDFLGLTTLTILD A RYIR LDP+ AD++ + +PL Sbjct: 541 QGGEDAGVVSQYDKDDVEAVGLVKFDFLGLTTLTILDWAERYIRTLDPSRADWNCSHIPL 600 Query: 598 DDRPSYELLTKAKTVAVFQLESRGMQGMLKDARPDRFEDIIALVALYRPGPMDLIPDFCK 657 D+ ++++L A TVAVFQLESRGMQGMLKDA+PDRFEDIIALVALYRPGPMDLIP FC Sbjct: 601 TDKAAFDILKTANTVAVFQLESRGMQGMLKDAKPDRFEDIIALVALYRPGPMDLIPSFCA 660 Query: 658 RKHG-EAFDYPDPRTEGILSETYGIMVYQEQVMQMAQVIGGYSLGGADLLRRAMGKKKAE 716 RKHG E +YPDPR E +L ETYGIMVYQEQVMQMAQ++GGYSLGGADLLRRAMGKKKAE Sbjct: 661 RKHGREKVEYPDPRVEPVLKETYGIMVYQEQVMQMAQIVGGYSLGGADLLRRAMGKKKAE 720 Query: 717 EMAKHRELFREGAAKNGLDQAKADEIFDLMEKFAGYGFNKSHAAAYALLSYYTAYLKAHH 776 EMA+HRELFR GAAK+GL KADEIFDLMEKFAGYGFNKSHAAAYALL+YYTA+LKAHH Sbjct: 721 EMAEHRELFRGGAAKDGLSTEKADEIFDLMEKFAGYGFNKSHAAAYALLAYYTAWLKAHH 780 Query: 777 PAAFMAANLSLAMEDTDKVKILIEDSIDICKLAILPPDINKSDYRFMPVGEPGKKATQIR 836 PA FMAAN+SLAM+DTDKVKIL +D+ LA+LPPDIN S YRF P A IR Sbjct: 781 PAEFMAANMSLAMDDTDKVKILYDDARGKNGLAVLPPDINASQYRFTPT-----DAKTIR 835 Query: 837 YGLGAVKGAGQNAIEAILEARKSGPFKDLFDFAKRVDKKQINRRTIDSLIRAGAFDCFKV 896 YGLG VKG+GQ AIE IL AR+ GPFKDLFDF +RVD++Q+NRRTI++L+RAGAFD Sbjct: 836 YGLGGVKGSGQGAIEDILRAREDGPFKDLFDFCERVDRRQVNRRTIEALVRAGAFDSLNA 895 Query: 897 DRAILQASVNLAWESAEQAEKSANQVSLF---GGDDSDLEAPLEYVQVPPWSDKQRLTEE 953 +RA L S+ LA E+AEQ +ANQVSLF G DD++ P E + PWS K++L EE Sbjct: 896 NRAQLLVSIGLAMEAAEQKAAAANQVSLFDLMGSDDAEQHRP-ELLDEAPWSTKRKLQEE 954 Query: 954 KGALGFYLSGHLFSAYEKEVRRFVRTKIASL---------------EPSWEPRSLAGIIT 998 K ALGFYLSGHLF EVRRF RT +A L +++AG+I Sbjct: 955 KQALGFYLSGHLFDECRDEVRRFARTTLADLAREVNGNGNNGGGYGSRDARNKTVAGVIV 1014 Query: 999 GVRVQMTQRGKLVICTLDDGTG--VIEATIYNELFEPFKHLIKEDELLVVSGKVSEDRFN 1056 G+R QMTQRGK+++ LDDG+ E T++NELF+ + L KEDE+L+V G D F Sbjct: 1015 GLRTQMTQRGKMIVVMLDDGSQSEATEVTVFNELFDANRALFKEDEVLIVQGNARHDTFT 1074 Query: 1057 GGLRVAADKVMDLGAARIQYGVRMVVSINKAIDPNHLRDTLSAHRQEQ--GLPFVMRYQQ 1114 GG+R+ A+ V+DL AR +Y + ++ LR+ L+ + Q G+ + Y Sbjct: 1075 GGVRMTAEAVLDLTQARARYADAIGLTFRDNASAARLRELLTPYLAAQVPGVRVRISYAA 1134 Query: 1115 ADAACEVVLGDAWRINPSDSLQSTLVASFGKEAVVVEY 1152 A CE VLG+ W++ PSD + ++ ++ E V + Y Sbjct: 1135 NGARCEAVLGEQWQVTPSDEVLASFRSALSTENVYMIY 1172 >NMB1827 [L] COG0587 DNA polymerase III, alpha subunit Nme Neisseria meningitidis MC58 Length = 1144 Score = 1139 bits (2946), Expect = 0.0, Method: Compositional matrix adjust. Identities = 591/1163 (50%), Positives = 788/1163 (67%), Gaps = 30/1163 (2%) Query: 1 MTTPQFVHLRMHSEYSIVDGLVRIDDIVKAAAKDGQAALAVTDLANLFCMVRFYKEARGK 60 MT P ++ LR+H+E+SI DG+VRI ++ A + G AL ++DL N F +V+FYK R Sbjct: 1 MTEPTYIPLRLHTEFSITDGMVRIKKLIAKAQEYGLPALGISDLMNEFGLVKFYKACRSA 60 Query: 61 GVKPIAGCDLWITNDADREKPFRLLVLIKNRHGYLQLCEVLSQAWL-NNQYKGRAEVRME 119 G+KPI D+ I N +KPFR +++I+N GYL+L E+L+ A++ ++ AE+ E Sbjct: 61 GIKPIGAADVRIGNPDAPDKPFRAMLIIRNDAGYLRLSELLTAAYVGKDRNVHHAELNPE 120 Query: 120 WLEALRHQEGGN-GLIALSGAAMGDIGQAIDNGNLTQAEACARRWAEIFPGAFYLELQRA 178 WLE G N GLI LSGA G++G + NGN A A ++A FP AFY+ELQR Sbjct: 121 WLE-----NGDNSGLICLSGAHYGEVGVNLLNGNEDAARTAALKYAAWFPDAFYMELQRL 175 Query: 179 GQ-ANMELQVRQSVALGAKLGLPCVATHPIQFQSPEEFIAHEARTCIAEGEIMANARRVR 237 + E V SV L +LGLP VATHP QF S ++F AHEAR CIA G ++ + +R R Sbjct: 176 PERPEWEACVSGSVKLAEELGLPVVATHPTQFMSRDDFNAHEARVCIAGGWVLTDKKRPR 235 Query: 238 RFNEQQYFKSQAEMAELFADLPGALANSVEIAKRCNLVLQLGKPQLPDFPTPDGMSIDDF 297 F Q+F MAE FADLP AL N+VEIAKRCNL + LGK LP FPTPDG+S+DD+ Sbjct: 236 DFTPGQFFIPPETMAERFADLPEALENTVEIAKRCNLHITLGKNFLPLFPTPDGLSLDDY 295 Query: 298 LVAQTKAGLEVRLKELFPNEAEREKQRPRYEARLEFENNTIIKMKFPGYFLIVADFIQWA 357 L+ + GL+ R+ +L+P+EAER + P Y+ RL+FE N II+MKFPGYFLIV DFI WA Sbjct: 296 LIKLSNEGLQERMVQLYPDEAERAAKMPEYQERLDFELNIIIQMKFPGYFLIVQDFINWA 355 Query: 358 KNNGVPVGPGRGSGAGSLVAYCLLITDLDPLRYNLLFERFLNPERVSMPDFDIDFCQEGR 417 K +G PVGPGRGSGAGSLVAY L ITDLDPL+Y LLFERFLNPERVSMPDFD+DFCQ R Sbjct: 356 KTHGCPVGPGRGSGAGSLVAYSLKITDLDPLKYALLFERFLNPERVSMPDFDVDFCQSNR 415 Query: 418 DRVIQYVKDRYGKDAVSQIATFGTMAAKGAVRDVGRVLDLGYNFCDGISKLIPFKPGKLV 477 RVI+YV+++YG +AVSQI TFGTM++K +RDVGRVL+L + CD +SKLIP + K + Sbjct: 416 GRVIEYVREKYGAEAVSQIVTFGTMSSKAVIRDVGRVLELPFMLCDKLSKLIPLEANKPL 475 Query: 478 TLADAIEEEPLLKERLENEEEVKQLMGLAQQVEGIARNIGMHAGGVLIAPGKLTDFCPLY 537 +L A+E EP ++E +E EE +L+ LA+++E + R +GMHAGGVLIAPGK++D+ P+Y Sbjct: 476 SLEKAMETEPQIQELIE-AEEADELITLAKKLEDLTRGLGMHAGGVLIAPGKISDYSPVY 534 Query: 538 TQGGDSGVVSQYDKDDVEAVGLVKFDFLGLTTLTILDRAVRYIRMLDPAMADFDLAKLPL 597 + VS YDK DVE VGLVKFDFLGL LTI++ A I+ + D+ K+PL Sbjct: 535 QADESASPVSMYDKGDVEDVGLVKFDFLGLRNLTIIEMAQNNIKNTTGDI--IDVGKIPL 592 Query: 598 DDRPSYELLTKAKTVAVFQLESRGMQGMLKDARPDRFEDIIALVALYRPGPMDLIPDFCK 657 DD+ +Y++ A T AVFQ ES GM+ MLK A +FE++IA V+LYRPGPMD IPDF Sbjct: 593 DDQVAYQIFRDANTTAVFQFESTGMKKMLKTAHTTKFEELIAFVSLYRPGPMDNIPDFVA 652 Query: 658 RKHGEAFDYPDPRTEGILSETYGIMVYQEQVMQMAQVIGGYSLGGADLLRRAMGKKKAEE 717 R G+ F Y P EGIL+ TYGIMVYQEQVMQ AQ+IGGYSLGGADLLRRAMGKKK EE Sbjct: 653 RMKGQEFQYIHPLLEGILAPTYGIMVYQEQVMQAAQIIGGYSLGGADLLRRAMGKKKPEE 712 Query: 718 MAKHRELFREGAAKNGLDQAKADEIFDLMEKFAGYGFNKSHAAAYALLSYYTAYLKAHHP 777 M KHRE+F EGAAK G+ + K+DEIF+ MEKFAGYGFNKSHAAAYAL+SY TA+LKAH+P Sbjct: 713 MVKHREIFAEGAAKQGISREKSDEIFNYMEKFAGYGFNKSHAAAYALISYQTAWLKAHYP 772 Query: 778 AAFMAANLSLAMEDTDKVKILIEDSIDICK---LAILPPDINKSDYRFMPVGEPGKKATQ 834 A FMAA +S +++TD++K +D C+ + LPPDIN+SDYRF P + + Sbjct: 773 AEFMAATMSSELDNTDQLKHFYDD----CRANGIEFLPPDINESDYRFTPYPD-----MK 823 Query: 835 IRYGLGAVKGAGQNAIEAILEARKS-GPFKDLFDFAKRVDKKQINRRTIDSLIRAGAFDC 893 IRY LGA+KG G+ A+E+I AR+S G F L DF +RV K+ +NRRT+++LIR GAFD Sbjct: 824 IRYALGAIKGTGEAAVESITAARQSGGKFTGLLDFCERVGKEHMNRRTLEALIRGGAFDS 883 Query: 894 FKVDRAILQASVNLAWESAEQAEKSANQVSLFGGDDSDLEAPLEYVQVPPWSDKQRLTEE 953 + +RA+L A+++LA ++A+Q +ANQ LF + +E P+ + P WS+ ++L EE Sbjct: 884 IEPNRAMLLANIDLAMDNADQKAANANQGGLFDMMEDAIE-PVRLIDAPMWSESEKLAEE 942 Query: 954 KGALGFYLSGHLFSAYEKEVRRFVRTKIASLEPSWEPRSLAGIITGVRVQMTQRGKLVIC 1013 K +GFYLSGH F Y +EVR+ TK+ L+P R LAG +T VR M +RGK+ Sbjct: 943 KTVIGFYLSGHPFGPYAQEVRQIAPTKLDRLKPQDSVR-LAGFVTAVRTMMGKRGKIAFV 1001 Query: 1014 TLDDGTGVIEATIYNELFEPFKHLIKEDELLVVSGKVSEDRFNG--GLRVAADKVMDLGA 1071 +L+D +G +E + + E +K D++L++ KVS D + G GLR+ A++VM L Sbjct: 1002 SLEDLSGQVEIMVGGQTLENCADCLKADQVLIIESKVSRDDYGGGDGLRILANQVMTLQT 1061 Query: 1072 ARIQYGVRMVVSINKAIDPNHLRDTLSAHR--QEQGLPFVMRYQQADAACEVVLGDAWRI 1129 AR +Y + +++ D L L+AH+ +P + Y A+ + + W + Sbjct: 1062 ARERYARSLSLALAPHHDIGGLVRLLAAHQLPDTPRIPLQLSYANEKASGRLQVPPKWTV 1121 Query: 1130 NPSDSLQSTLVASFGKEAVVVEY 1152 PS +L L G +V V + Sbjct: 1122 TPSSALFGELETLLGSRSVRVNW 1144 >NMA0632 [L] COG0587 DNA polymerase III, alpha subunit NmA Neisseria meningitidis Z2491 Length = 1144 Score = 1130 bits (2922), Expect = 0.0, Method: Compositional matrix adjust. Identities = 591/1163 (50%), Positives = 787/1163 (67%), Gaps = 30/1163 (2%) Query: 1 MTTPQFVHLRMHSEYSIVDGLVRIDDIVKAAAKDGQAALAVTDLANLFCMVRFYKEARGK 60 MT P ++ LR+H+E+SI DG+VRI ++ A + G AL ++DL N F +V+FYK R Sbjct: 1 MTEPTYIPLRLHTEFSITDGMVRIKKLIAKAQEYGLPALGISDLMNEFGLVKFYKACRSA 60 Query: 61 GVKPIAGCDLWITNDADREKPFRLLVLIKNRHGYLQLCEVLSQAWL-NNQYKGRAEVRME 119 G+KPI D+ I N +KPFR +++I+N GYL+L E+L+ A++ ++ AE+ E Sbjct: 61 GIKPIGAADVRIGNPDAPDKPFRAMLIIRNDAGYLRLSELLTAAYVGKDRNVHHAELNPE 120 Query: 120 WLEALRHQEGGN-GLIALSGAAMGDIGQAIDNGNLTQAEACARRWAEIFPGAFYLELQRA 178 WLE G N GLI LSGA G++G + NGN A A A ++A FP AFYLELQR Sbjct: 121 WLE-----NGDNSGLICLSGAHYGEVGVNLLNGNEDAARAAALKYAAWFPDAFYLELQRL 175 Query: 179 GQ-ANMELQVRQSVALGAKLGLPCVATHPIQFQSPEEFIAHEARTCIAEGEIMANARRVR 237 + E V SV L +LGLP VATHP QF S ++F AHEAR CIA G ++ + +R R Sbjct: 176 PERPEWEACVSGSVKLAEELGLPVVATHPTQFMSRDDFNAHEARVCIAGGWVLTDKKRPR 235 Query: 238 RFNEQQYFKSQAEMAELFADLPGALANSVEIAKRCNLVLQLGKPQLPDFPTPDGMSIDDF 297 F Q+F MAE F+DLP AL N+VEIAKRCNL + LGK LP FPTPDG+S+DD+ Sbjct: 236 DFTPSQFFIPPETMAERFSDLPEALENTVEIAKRCNLHITLGKNFLPLFPTPDGLSLDDY 295 Query: 298 LVAQTKAGLEVRLKELFPNEAEREKQRPRYEARLEFENNTIIKMKFPGYFLIVADFIQWA 357 LV + GL+ R+ +L+P+EAER + P Y+ RL+FE N II+MKFPGYFLIV DFI WA Sbjct: 296 LVKLSNEGLQERMVQLYPDEAERAAKMPEYQERLDFELNIIIQMKFPGYFLIVQDFINWA 355 Query: 358 KNNGVPVGPGRGSGAGSLVAYCLLITDLDPLRYNLLFERFLNPERVSMPDFDIDFCQEGR 417 K +G PVGPGRGSGAGSLVAY L ITDLDPL+Y LLFERFLNPERVSMPDFD+DFCQ R Sbjct: 356 KTHGCPVGPGRGSGAGSLVAYSLKITDLDPLKYALLFERFLNPERVSMPDFDVDFCQANR 415 Query: 418 DRVIQYVKDRYGKDAVSQIATFGTMAAKGAVRDVGRVLDLGYNFCDGISKLIPFKPGKLV 477 RVI+YV+++YG +AVSQI TFGTM++K +RDVGRVL+L + CD +SKLIP + K + Sbjct: 416 GRVIEYVREKYGAEAVSQIVTFGTMSSKAVIRDVGRVLELPFTLCDKLSKLIPLEANKPL 475 Query: 478 TLADAIEEEPLLKERLENEEEVKQLMGLAQQVEGIARNIGMHAGGVLIAPGKLTDFCPLY 537 L DA++ EP ++E +E EE +L+ LA+++E + R +GMHAGGVLIAPGK++D+ P+Y Sbjct: 476 GLDDAMKAEPQIQELIE-AEEADELITLAKKLEDLTRGLGMHAGGVLIAPGKISDYSPVY 534 Query: 538 TQGGDSGVVSQYDKDDVEAVGLVKFDFLGLTTLTILDRAVRYIRMLDPAMADFDLAKLPL 597 + VS YDK DVE VGLVKFDFLGL LTI++ A I+ + D+ +PL Sbjct: 535 QADESASPVSMYDKGDVEDVGLVKFDFLGLRNLTIIEMAQNNIKNTTGDIV--DVGTIPL 592 Query: 598 DDRPSYELLTKAKTVAVFQLESRGMQGMLKDARPDRFEDIIALVALYRPGPMDLIPDFCK 657 DD+ +Y++ A T AVFQ ES GM+ MLK A +FE++IA V+LYRPGPMD IPDF Sbjct: 593 DDQTAYQIFRDANTTAVFQFESTGMKKMLKTAHTTKFEELIAFVSLYRPGPMDNIPDFVA 652 Query: 658 RKHGEAFDYPDPRTEGILSETYGIMVYQEQVMQMAQVIGGYSLGGADLLRRAMGKKKAEE 717 R G+ F Y P EGIL+ TYGIMVYQEQVMQ AQ+IGGYSLGGADLLRRAMGKKK EE Sbjct: 653 RMKGQEFQYIHPLLEGILAPTYGIMVYQEQVMQAAQIIGGYSLGGADLLRRAMGKKKPEE 712 Query: 718 MAKHRELFREGAAKNGLDQAKADEIFDLMEKFAGYGFNKSHAAAYALLSYYTAYLKAHHP 777 M KHRE+F EGAAK G+ + K+DEIF+ MEKFAGYGFNKSHAAAYAL+SY TA+LKAH+P Sbjct: 713 MVKHREIFAEGAAKQGISREKSDEIFNYMEKFAGYGFNKSHAAAYALISYQTAWLKAHYP 772 Query: 778 AAFMAANLSLAMEDTDKVKILIEDSIDICK---LAILPPDINKSDYRFMPVGEPGKKATQ 834 A FMAA +S +++TD++K +D C+ + LPPDIN+SDYRF P + + Sbjct: 773 AEFMAATMSSELDNTDQLKHFYDD----CRANGIEFLPPDINESDYRFTPYPD-----MK 823 Query: 835 IRYGLGAVKGAGQNAIEAILEARKS-GPFKDLFDFAKRVDKKQINRRTIDSLIRAGAFDC 893 IRY LGA+KG G+ A+E+I AR+S G F L DF +RV K+ +NRRT+++LIR GAFD Sbjct: 824 IRYALGAIKGTGEAAVESITSARQSGGKFTGLLDFCERVGKEHMNRRTLEALIRGGAFDS 883 Query: 894 FKVDRAILQASVNLAWESAEQAEKSANQVSLFGGDDSDLEAPLEYVQVPPWSDKQRLTEE 953 + +RA+L A+++LA +A+Q +ANQ LF + +E P+ + P WS+ ++L EE Sbjct: 884 IEPNRAMLLANIDLAMNNADQKAANANQGGLFDMMEDAIE-PVRLIDAPMWSESEKLAEE 942 Query: 954 KGALGFYLSGHLFSAYEKEVRRFVRTKIASLEPSWEPRSLAGIITGVRVQMTQRGKLVIC 1013 K +GFYLSGH F Y +EVR+ K++ L+P R LAG +T VR M +RGK+ Sbjct: 943 KTVIGFYLSGHPFGPYAQEVRQIAPQKLSKLKPQDSVR-LAGFVTAVRTMMGKRGKIAFV 1001 Query: 1014 TLDDGTGVIEATIYNELFEPFKHLIKEDELLVVSGKVSEDRFNG--GLRVAADKVMDLGA 1071 +L+D +G +E + + E +K D++L++ KVS D + G GLR+ A++VM L Sbjct: 1002 SLEDLSGQVEIMVGGQTLENCADCLKADQVLIIESKVSRDDYGGGDGLRILANQVMTLQT 1061 Query: 1072 ARIQYGVRMVVSINKAIDPNHLRDTLSAHR--QEQGLPFVMRYQQADAACEVVLGDAWRI 1129 AR +Y + +++ D L L+AH+ +P + Y A+ + + W + Sbjct: 1062 ARERYARSLSLALAPHHDIGELVQLLAAHQLPDTPRIPLQLSYANEKASGRLQVPPKWTV 1121 Query: 1130 NPSDSLQSTLVASFGKEAVVVEY 1152 PS +L L G +V V + Sbjct: 1122 TPSSALFGELETLLGSRSVRVNW 1144 >PA3640 [L] COG0587 DNA polymerase III, alpha subunit Pae Pseudomonas aeruginosa Length = 1173 Score = 1108 bits (2865), Expect = 0.0, Method: Compositional matrix adjust. Identities = 598/1190 (50%), Positives = 792/1190 (66%), Gaps = 59/1190 (4%) Query: 3 TPQFVHLRMHSEYSIVDGLVRIDDIVKAAAKDGQAALAVTDLANLFCMVRFYKEARGKGV 62 T FVHLR+H+E+S+VDGLVR+ + KA A G A+AVTD +N+ +V+FYK A G G+ Sbjct: 2 TVSFVHLRLHTEFSLVDGLVRVKPLAKAVAGLGMPAVAVTDQSNMCSLVKFYKTAMGAGI 61 Query: 63 KPIAGCDLWITNDADREKPFRLLVLIKNRHGYLQLCEVLSQAWLNNQYKGRAEVRMEWLE 122 KPI G D+W+ + + RL +L N GY L E++S+ W Q G + +W+ Sbjct: 62 KPICGADIWLASREEDGPLSRLSLLAMNAKGYRNLTELISRGWSEGQRNGEIIIERDWV- 120 Query: 123 ALRHQEGGNGLIALSGAAMGDIGQAIDNGNLTQAEACARRWAEIFPGAFYLELQRAGQAN 182 +E GLIALS A G+IG A+ +G +AEA R W E+FP FY+E+QR + N Sbjct: 121 ----KEAAEGLIALSAAKEGEIGHALLDGEEAKAEALLREWMEVFPERFYVEVQRTSRVN 176 Query: 183 MELQVRQSVALGAKLGLPCVATHPIQFQSPEEFIAHEARTCIAEGEIMANARRVRRFNEQ 242 E + +VAL ++ P VAT+ ++F E+F AHE R CI EG + + RR R +++Q Sbjct: 177 DEEHLHAAVALASRCNAPLVATNDVRFIKQEDFEAHETRVCIGEGRTLDDPRRPRTYSDQ 236 Query: 243 QYFKSQAEMAELFADLPGALANSVEIAKRCNLVLQLGKPQLPDFPTPDGMSIDDFLVAQT 302 QY KS AEMAELF+DLP AL N+VEIAKRCN+ +QLGK LPDFPTP+GM IDD+L + Sbjct: 237 QYLKSPAEMAELFSDLPEALENTVEIAKRCNIEVQLGKYFLPDFPTPNGMGIDDYLRHAS 296 Query: 303 KAGLEVRLKELFPNEA-EREKQRPRYEARLEFENNTIIKMKFPGYFLIVADFIQWAKNNG 361 GLE RL+ L P + + E +R Y RL FE + II+M FPGYFLIV DFI+WAKNNG Sbjct: 297 FEGLEERLEVLLPKDTPDYEAKRQVYVDRLNFELDIIIQMGFPGYFLIVMDFIKWAKNNG 356 Query: 362 VPVGPGRGSGAGSLVAYCLLITDLDPLRYNLLFERFLNPERVSMPDFDIDFCQEGRDRVI 421 VPVGPGRGSGAGSLVAY L ITDLDPL Y+LLFERFLNPER+SMPDFD+DFC EGRDRVI Sbjct: 357 VPVGPGRGSGAGSLVAYVLKITDLDPLAYDLLFERFLNPERISMPDFDVDFCMEGRDRVI 416 Query: 422 QYVKDRYGKDAVSQIATFGTMAAKGAVRDVGRVLDLGYNFCDGISKLIPFKPGKLVTLAD 481 YV D YG++AVSQI TFGTMAAK VRDV RV Y D +SK+IPF+ G +TL Sbjct: 417 DYVADAYGRNAVSQIITFGTMAAKAVVRDVARVQGKSYGLADRLSKMIPFEVG--MTLDK 474 Query: 482 AIEEEPLLKERLENEEEVKQLMGLAQQVEGIARNIGMHAGGVLIAPGKLTDFCPLYTQGG 541 A E+E +L++ L+++EE ++ +A ++EGI R G HAGGV+IAP KLTDF P+ Sbjct: 475 AYEQEEMLRDFLKSDEEAAEIWEMALKLEGITRGTGKHAGGVVIAPTKLTDFSPIACDEE 534 Query: 542 DSGVVSQYDKDDVEAVGLVKFDFLGLTTLTILDRAVRYI------RMLDPAMADFDLAKL 595 G+V+Q+DKDDVEA GLVKFDFLGL TLTI+ A+ I + L+P DF + Sbjct: 535 GGGLVTQFDKDDVEAAGLVKFDFLGLRTLTIIKWAMEIINREQAKKGLEPVNIDF----I 590 Query: 596 PLDDRPSYELLTKAKTVAVFQLESRGMQGMLKDARPDRFEDIIALVALYRPGPMD--LIP 653 PLDD+P+Y LL KA+T AVFQLESRGM+ ++K +PD ED+IALVAL+RPGP+ ++ Sbjct: 591 PLDDKPTYSLLQKAETTAVFQLESRGMKELIKKLKPDCLEDLIALVALFRPGPLQSGMVD 650 Query: 654 DFCKRKHGEA-FDYPDPR-----TEGILSETYGIMVYQEQVMQMAQVIGGYSLGGADLLR 707 DF RKHG A YP P E +L TYGI++YQEQVMQ+AQV+ GY+LGGAD+LR Sbjct: 651 DFINRKHGRAELSYPHPDYQYAGLEPVLKPTYGIILYQEQVMQIAQVMAGYTLGGADMLR 710 Query: 708 RAMGKKKAEEMAKHRELFREGAAKNGLDQAKADEIFDLMEKFAGYGFNKSHAAAYALLSY 767 RAMGKKK EEMAK R F EG NG+D A IFDL+EKFAGYGFNKSH+AAY L+SY Sbjct: 711 RAMGKKKPEEMAKQRGGFIEGCKNNGIDADLAGNIFDLVEKFAGYGFNKSHSAAYGLVSY 770 Query: 768 YTAYLKAHHPAAFMAANLSLAMEDTDKVKILIEDSIDICKLAILPPDINKSDYRFMPVGE 827 TA+LK H PA FMAA L+ M++TDKV LIE+ + KL I+ PD+N S++RF V + Sbjct: 771 QTAWLKTHFPAPFMAAVLTADMQNTDKVVTLIEECRHM-KLRIVAPDVNNSEFRFT-VDD 828 Query: 828 PGKKATQIRYGLGAVKGAGQNAIEAILEAR-KSGPFKDLFDFAKRVDKKQINRRTIDSLI 886 G+ I YGLGA+KG G+ +EAI E R + GPF LFDF RVD K+IN+RT+++LI Sbjct: 829 DGR----IVYGLGAIKGVGEGPVEAITECRAEGGPFNTLFDFCDRVDLKRINKRTLEALI 884 Query: 887 RAGAFD---------------CFKVDRAILQASVNLAWESAEQAEKS--ANQVSLFGGDD 929 RAGA D ++RA+L A++ A ++AEQ +S + + LFGG Sbjct: 885 RAGALDRLGPHYHDELKAYQATVDLNRAVLLAAMEEAIQAAEQTARSHDSGHMDLFGGVF 944 Query: 930 SDLEAPL--EYVQVPPWSDKQRLTEEKGALGFYLSGHLFSAYEKEVRRFVRTKIASLEPS 987 ++ EA + + +V + K+RL EK LG YL+GH YE EVRRF R +I L+P+ Sbjct: 945 AEPEADVYANHRKVKELTLKERLKGEKDTLGLYLTGHPIDEYEGEVRRFARQRIVELKPA 1004 Query: 988 WEPRSLAGIITGVRVQMTQRG-KLVICTLDDGTGVIEATIYNELFEPFKHLIKEDELLVV 1046 + +++AG+I +RV ++G K+ TLDD +G IEA++++E F + L++ D L+VV Sbjct: 1005 RDTQTVAGLIVNLRVMKNKKGDKMGFVTLDDRSGRIEASLFSEAFAAAQSLLQTDALVVV 1064 Query: 1047 SGKVSEDRFNGGLRVAADKVMDLGAAR--IQYGVRMVVSIN--KAIDPNHLRDTLSAHRQ 1102 G+VS+D F+GGLR+ A +VM L AR + +RM + + K L + + HR Sbjct: 1065 EGEVSQDDFSGGLRLRAKRVMSLEEARTGLAESLRMKLHADLLKGDRLRWLGELFNRHR- 1123 Query: 1103 EQGLPFVMRYQQADAACEVVLGDAWRINPSDSLQSTLVASFGKEAVVVEY 1152 P + Y ADA + G++WR++P+D L L FG++ V + Y Sbjct: 1124 -GSCPITLDYTSADAKALLQFGESWRVDPADDLIQALRDQFGRDNVFLNY 1172 >ZdnaE [L] COG0587 DNA polymerase III, alpha subunit EcZ Escherichia coli O157:H7 EDL933 Length = 1160 Score = 1060 bits (2742), Expect = 0.0, Method: Compositional matrix adjust. Identities = 575/1174 (48%), Positives = 779/1174 (66%), Gaps = 37/1174 (3%) Query: 1 MTTPQFVHLRMHSEYSIVDGLVRIDDIVKAAAKDGQAALAVTDLANLFCMVRFYKEARGK 60 M+ P+FVHLR+HS+YS++DGL + +VK AA G ALA+TD NL +V+FY G Sbjct: 1 MSEPRFVHLRVHSDYSMIDGLAKTAPLVKKAAALGMPALAITDFTNLCGLVKFYGAGHGA 60 Query: 61 GVKPIAGCDLWITNDADREKPFRLLVLIKNRHGYLQLCEVLSQAWLNNQYKGRAEVRMEW 120 G+KPI G D + D ++ L VL N GY L ++S+A+ + +W Sbjct: 61 GIKPIVGADFNVQCDLLGDELTHLTVLAANNTGYQNLTLLISKAYQRGYGAAGPIIDRDW 120 Query: 121 LEALRHQEGGNGLIALSGAAMGDIGQAIDNGNLTQAEACARRWAEIFPGAFYLELQRAGQ 180 L L GLI LSG MGD+G+++ GN + C + E FP ++LEL R G+ Sbjct: 121 LIEL-----NEGLILLSGGRMGDVGRSLLRGNSALVDECVAFYEEHFPDRYFLELIRTGR 175 Query: 181 ANMELQVRQSVALGAKLGLPCVATHPIQFQSPEEFIAHEARTCIAEGEIMANARRVRRFN 240 + E + +V L GLP VAT+ ++F +F AHE R I +G + + +R R ++ Sbjct: 176 PDEESYLHAAVELAEARGLPVVATNDVRFIDSSDFDAHEIRVAIHDGFTLDDPKRPRNYS 235 Query: 241 EQQYFKSQAEMAELFADLPGALANSVEIAKRCNLVLQLGKPQLPDFPTPDGMSIDDFLVA 300 QQY +S+ EM ELFAD+P ALAN+VEIAKRCN+ ++LG+ LP FPT D MS +D+LV Sbjct: 236 PQQYMRSEEEMCELFADIPEALANTVEIAKRCNVTVRLGEYFLPQFPTGD-MSTEDYLVK 294 Query: 301 QTKAGLEVRLKELFPNEAEREKQRPRYEARLEFENNTIIKMKFPGYFLIVADFIQWAKNN 360 + K GLE RL LFP+E ER K+RP Y+ RLE E I +M FPGYFLIV +FIQW+K+N Sbjct: 295 RAKEGLEERLAFLFPDEEERVKRRPEYDERLETELQVINQMGFPGYFLIVMEFIQWSKDN 354 Query: 361 GVPVGPGRGSGAGSLVAYCLLITDLDPLRYNLLFERFLNPERVSMPDFDIDFCQEGRDRV 420 GVPVGPGRGSGAGSLVAY L ITDLDPL ++LLFERFLNPERVSMPDFD+DFC E RD+V Sbjct: 355 GVPVGPGRGSGAGSLVAYALKITDLDPLEFDLLFERFLNPERVSMPDFDVDFCMEKRDQV 414 Query: 421 IQYVKDRYGKDAVSQIATFGTMAAKGAVRDVGRVLDLGYNFCDGISKLIPFKPGKLVTLA 480 I++V D YG+DAVSQI TFGTMAAK +RDVGRVL Y F D ISKLIP PG +TLA Sbjct: 415 IEHVADMYGRDAVSQIITFGTMAAKAVIRDVGRVLGHPYGFVDRISKLIPPDPG--MTLA 472 Query: 481 DAIEEEPLLKERLENEEEVKQLMGLAQQVEGIARNIGMHAGGVLIAPGKLTDFCPLYTQG 540 A E EP L E E +EEVK L+ +A+++EG+ RN G HAGGV+IAP K+TDF PLY Sbjct: 473 KAFEAEPQLPEIYEADEEVKALIDMARKLEGVTRNAGKHAGGVVIAPTKITDFAPLYCDE 532 Query: 541 GDSGVVSQYDKDDVEAVGLVKFDFLGLTTLTILDRAVRYI--RMLDPAMADFDLAKLPLD 598 V+Q+DK DVE GLVKFDFLGL TLTI++ A+ I R D+A +PLD Sbjct: 533 EGKHPVTQFDKSDVEYAGLVKFDFLGLRTLTIINWALEMINKRRAKNGEPPLDIAAIPLD 592 Query: 599 DRPSYELLTKAKTVAVFQLESRGMQGMLKDARPDRFEDIIALVALYRPGPMD--LIPDFC 656 D+ S+++L +++T AVFQLESRGM+ ++K +PD FED+IALVAL+RPGP+ ++ +F Sbjct: 593 DKKSFDMLQRSETTAVFQLESRGMKDLIKRLQPDCFEDMIALVALFRPGPLQSGMVDNFI 652 Query: 657 KRKHG-EAFDYPDPRTEG-----ILSETYGIMVYQEQVMQMAQVIGGYSLGGADLLRRAM 710 RKHG E YPD + + +L TYGI++YQEQVMQ+AQV+ GY+LGGAD+LRRAM Sbjct: 653 DRKHGREEISYPDVQWQHESLKPVLEPTYGIILYQEQVMQIAQVLSGYTLGGADMLRRAM 712 Query: 711 GKKKAEEMAKHRELFREGAAKNGLDQAKADEIFDLMEKFAGYGFNKSHAAAYALLSYYTA 770 GKKK EEMAK R +F EGA KNG++ A +IFDL+EKFAGYGFNKSH+AAYAL+SY T Sbjct: 713 GKKKPEEMAKQRSVFAEGAEKNGINAELAMKIFDLVEKFAGYGFNKSHSAAYALVSYQTL 772 Query: 771 YLKAHHPAAFMAANLSLAMEDTDKVKILIEDSIDICKLAILPPDINKSDYRFMPVGEPGK 830 +LKAH+PA FMAA ++ M++T+KV L+++ + L ILPPDIN Y F V + G Sbjct: 773 WLKAHYPAEFMAAVMTADMDNTEKVVGLVDECWRM-GLKILPPDINSGLYHFH-VNDDG- 829 Query: 831 KATQIRYGLGAVKGAGQNAIEAILEAR-KSGPFKDLFDFAKRVDKKQINRRTIDSLIRAG 889 +I YG+GA+KG G+ IEAI+EAR K G F++LFD R D K++NRR ++ LI +G Sbjct: 830 ---EIVYGIGAIKGVGEGPIEAIIEARNKGGYFRELFDLCARTDTKKLNRRVLEKLIMSG 886 Query: 890 AFDCFKVDRAILQASVNLAWESAEQAEKSA--NQVSLFGGDDSDLEA-PLEYVQVPPWSD 946 AFD RA L S+ A ++A+Q K+ Q +FG + E Y PW + Sbjct: 887 AFDRLGPHRAALMNSLGDALKAADQHAKAEAIGQADMFGVLAEEPEQIEQSYASCQPWPE 946 Query: 947 KQRLTEEKGALGFYLSGHLFSAYEKEVRRFV-RTKIASLEPSWEPRSL--AGIITGVRVQ 1003 + L E+ LG YL+GH + Y KE+ R+V ++ + P+ + + AG++ RV Sbjct: 947 QVVLDGERETLGLYLTGHPINQYLKEIERYVGGVRLKDMHPTERGKVITAAGLVVAARVM 1006 Query: 1004 MTQRG-KLVICTLDDGTGVIEATIYNELFEPFKHLIKEDELLVVSGKVSEDRFNGGLRVA 1062 +T+RG ++ ICTLDD +G +E ++ + + ++HL+++D +L+VSG+VS D F+GGL++ Sbjct: 1007 VTKRGNRIGICTLDDRSGRLEVMLFTDALDKYQHLLEKDRILIVSGQVSFDDFSGGLKMT 1066 Query: 1063 ADKVMDLGAARIQYGVRMVVSI-NKAIDP---NHLRDTLSAHRQEQGLPFVMRYQQADAA 1118 A +VMD+ AR +Y + +S+ ++ ID N LR +L HR +P + YQ+ADA Sbjct: 1067 AREVMDIDEAREKYARGLAISLTDRQIDDQLLNRLRQSLEPHRSGT-IPVHLYYQRADAR 1125 Query: 1119 CEVVLGDAWRINPSDSLQSTLVASFGKEAVVVEY 1152 + G WR++PSD L + L G E V +E+ Sbjct: 1126 ARLRFGATWRVSPSDRLLNDLRGLIGSEQVELEF 1159