BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.3469.p (487 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2197 [J] COG1530 Ribonucleases G and E Rso Ralstonia solanace... 746 0.0 NMA0672 [J] COG1530 Ribonucleases G and E NmA Neisseria meningit... 572 e-163 NMB1791 [J] COG1530 Ribonucleases G and E Nme Neisseria meningit... 570 e-162 PA4477 [J] COG1530 Ribonucleases G and E Pae Pseudomonas aeruginosa 545 e-155 VC0419 [J] COG1530 Ribonucleases G and E Vch Vibrio cholerae 519 e-147 >RSc2197 [J] COG1530 Ribonucleases G and E Rso Ralstonia solanacearum Length = 489 Score = 746 bits (1926), Expect = 0.0, Method: Compositional matrix adjust. Identities = 371/491 (75%), Positives = 424/491 (86%), Gaps = 6/491 (1%) Query: 1 MSEDILINITPQETRVALILQGAVQELHIERTLSRGLAGNIYLGKVVRVLPGMQSAFIDI 60 MSEDIL+NITPQETRVA++ Q AVQELHIERTL+RGL GNIYLGKVVRVLPGMQSAFIDI Sbjct: 1 MSEDILVNITPQETRVAIVQQAAVQELHIERTLTRGLVGNIYLGKVVRVLPGMQSAFIDI 60 Query: 61 GLERAAFLHVADIWEARPHDGQNAPAIP---IEKLLHDGQTITVQVIKDPIGTKGARLST 117 GLERAAFLHVADIW P + ++APA P IEK L +GQ +TVQVIKDPIGTKGARLST Sbjct: 61 GLERAAFLHVADIWH--PREAKDAPAAPHVAIEKTLFEGQALTVQVIKDPIGTKGARLST 118 Query: 118 QISIAGRMLVYLPQDKHIGISQRIENEAERELLRSKVQALLPPEEKGGFIIRTMAEDASD 177 QISIAGR LVYLPQD HIGISQ+I NE +RE LR +V ++P +E+GGFI+RT+AE+A+D Sbjct: 119 QISIAGRTLVYLPQDPHIGISQKIGNETDREALRQRVTRMVPADERGGFIVRTIAEEATD 178 Query: 178 ADLQMDVEYLRTTWATITKQAKTKPAPTLLHQDLSLAQRVLRDFVSDHTATIQVDSRENF 237 +L DV YLR WATI A T PAP++L+QDL+LAQRVLRDFV+D T +IQ+DSREN+ Sbjct: 179 EELANDVAYLRKIWATIRHNATTLPAPSILYQDLNLAQRVLRDFVTDDTRSIQIDSRENY 238 Query: 238 HMLQEFGAIYTPSVLTKLMHYRGERPLFDLYGVEEEIERALGRRVDLKSGGYLIVDQTEA 297 L EF YTP+V+ +L HY GERP+FDLY +E E+ERAL RRVDLKSGGYL++DQTEA Sbjct: 239 QKLIEFAQEYTPAVVERLTHYTGERPIFDLYNIEAEVERALSRRVDLKSGGYLMIDQTEA 298 Query: 298 MTTIDVNTGSFVNGRNFDDTIFKTNLEAAHAIARQLRLRNLGGIIILDFIDMESTEHRQA 357 MTTIDVNTG +V RNFDDTIFKTNLEAAH IARQLRLRNLGGIII+DFIDMES EHR A Sbjct: 299 MTTIDVNTGGYVGARNFDDTIFKTNLEAAHTIARQLRLRNLGGIIIIDFIDMESGEHRDA 358 Query: 358 VLAELGKALQRDRTKISVSGFSTLGLVEMTRKRTRESLAHILCETCPACKGRGQVKTSRT 417 VLAEL +AL RDRT+I+V+ FS LGLVEMTRKRTRESLAH+LCE CP C+G+GQVKT RT Sbjct: 359 VLAELRRALARDRTRITVNSFSQLGLVEMTRKRTRESLAHVLCEQCPVCQGKGQVKTPRT 418 Query: 418 VCYEILREVMREAKQFNPREFRILASQVVVDMFLEEESQHLAMLGDFIGKPISLQVQS-D 476 VCY+ILRE+MRE++QFNPREFRILASQ V+D+FLEEESQHLAMLGDFIGKPISLQV+S Sbjct: 419 VCYDILREIMRESRQFNPREFRILASQSVIDLFLEEESQHLAMLGDFIGKPISLQVESAA 478 Query: 477 YQQEQYDIILM 487 QEQYDIILM Sbjct: 479 ASQEQYDIILM 489 >NMA0672 [J] COG1530 Ribonucleases G and E NmA Neisseria meningitidis Z2491 Length = 497 Score = 572 bits (1473), Expect = e-163, Method: Compositional matrix adjust. Identities = 295/487 (60%), Positives = 368/487 (75%), Gaps = 7/487 (1%) Query: 3 EDILINITPQETRVALILQGAVQELHIERTLSRGLAGNIYLGKVVRVLPGMQSAFIDIGL 62 E IL+NITPQETRVA++ + + ELHIER L GNIYLG V RVLPGMQSAFIDIGL Sbjct: 16 ETILVNITPQETRVAVLEENNICELHIERNSEHSLVGNIYLGVVRRVLPGMQSAFIDIGL 75 Query: 63 ERAAFLHVADIWEAR--PHDGQNAPAIPIEKLLHDGQTITVQVIKDPIGTKGARLSTQIS 120 ERAAFLH+ D+ E R P + Q IE +L +GQ++ VQVIKDPI TKGARLSTQIS Sbjct: 76 ERAAFLHIVDVLEQRRNPEETQR-----IEHMLFEGQSVLVQVIKDPINTKGARLSTQIS 130 Query: 121 IAGRMLVYLPQDKHIGISQRIENEAERELLRSKVQALLPPEEKGGFIIRTMAEDASDADL 180 +AGR LV+LPQ+ HIG+SQRIE++AER LR ++ LLP G+IIRT AE+A+D L Sbjct: 131 LAGRFLVHLPQEDHIGVSQRIEDDAERSSLRERLDKLLPENACRGYIIRTNAENATDEQL 190 Query: 181 QMDVEYLRTTWATITKQAKTKPAPTLLHQDLSLAQRVLRDFVSDHTATIQVDSRENFHML 240 Q D++YL W I +QAK +P TLL+QDL L+ RVLRD V T I VDS N + Sbjct: 191 QSDIDYLTKVWEHIQEQAKIRPPETLLYQDLPLSLRVLRDMVGCDTQKILVDSTVNHGRM 250 Query: 241 QEFGAIYTPSVLTKLMHYRGERPLFDLYGVEEEIERALGRRVDLKSGGYLIVDQTEAMTT 300 F Y L ++ ++GERPLF+ + VE+EI RAL RV+L G YLI++ TEAMTT Sbjct: 251 TRFAEQYVHGALGRIELFKGERPLFETHNVEQEISRALQPRVNLNFGSYLIIESTEAMTT 310 Query: 301 IDVNTGSFVNGRNFDDTIFKTNLEAAHAIARQLRLRNLGGIIILDFIDMESTEHRQAVLA 360 IDVNTG FV RNFD+TIF+TNLEA H IAR+LRLRNLGGIII+DFIDM HR+AVL Sbjct: 311 IDVNTGGFVGARNFDETIFRTNLEACHTIARELRLRNLGGIIIIDFIDMAQESHREAVLQ 370 Query: 361 ELGKALQRDRTKISVSGFSTLGLVEMTRKRTRESLAHILCETCPACKGRGQVKTSRTVCY 420 EL KAL DRT++++ GF++LGLVE+TRKR+RE+L +LCE CP+C+GRG++KT +TVCY Sbjct: 371 ELAKALAFDRTRVTLHGFTSLGLVELTRKRSRENLNQVLCEPCPSCQGRGRLKTPQTVCY 430 Query: 421 EILREVMREAKQFNPREFRILASQVVVDMFLEEESQHLAMLGDFIGKPISLQVQSDYQQE 480 EI RE++REA++++ FRILA+ V+D+FL+EESQ LAML DFIGKPISL V++ Y QE Sbjct: 431 EIQREIVREARRYDAESFRILAAPNVIDLFLDEESQSLAMLIDFIGKPISLAVETAYTQE 490 Query: 481 QYDIILM 487 QYDI+LM Sbjct: 491 QYDIVLM 497 >NMB1791 [J] COG1530 Ribonucleases G and E Nme Neisseria meningitidis MC58 Length = 509 Score = 570 bits (1468), Expect = e-162, Method: Compositional matrix adjust. Identities = 294/487 (60%), Positives = 367/487 (75%), Gaps = 7/487 (1%) Query: 3 EDILINITPQETRVALILQGAVQELHIERTLSRGLAGNIYLGKVVRVLPGMQSAFIDIGL 62 E IL+NITP ETRVA++ + + ELHIER L GNIYLG V RVLPGMQSAFIDIGL Sbjct: 28 ETILVNITPAETRVAVLEENNICELHIERNSEHSLVGNIYLGVVRRVLPGMQSAFIDIGL 87 Query: 63 ERAAFLHVADIWEAR--PHDGQNAPAIPIEKLLHDGQTITVQVIKDPIGTKGARLSTQIS 120 ERAAFLH+ D+ E R P + Q IE +L +GQ++ VQVIKDPI TKGARLSTQIS Sbjct: 88 ERAAFLHIVDVLEQRRNPEETQR-----IEHMLFEGQSVLVQVIKDPINTKGARLSTQIS 142 Query: 121 IAGRMLVYLPQDKHIGISQRIENEAERELLRSKVQALLPPEEKGGFIIRTMAEDASDADL 180 +AGR LV+LPQ+ HIG+SQRIE++AER LR ++ LLP G+IIRT AE+A+D L Sbjct: 143 LAGRFLVHLPQEDHIGVSQRIEDDAERSSLRERLDKLLPENACRGYIIRTNAENATDEQL 202 Query: 181 QMDVEYLRTTWATITKQAKTKPAPTLLHQDLSLAQRVLRDFVSDHTATIQVDSRENFHML 240 Q D++YL W I +QAK +P TLL+QDL L+ RVLRD V T I VDS N + Sbjct: 203 QSDIDYLTKVWEHIQEQAKIRPPETLLYQDLPLSLRVLRDMVGCDTQKILVDSTVNHGRM 262 Query: 241 QEFGAIYTPSVLTKLMHYRGERPLFDLYGVEEEIERALGRRVDLKSGGYLIVDQTEAMTT 300 F Y L ++ ++GERPLF+ + VE+EI RAL RV+L G YLI++ TEAMTT Sbjct: 263 TRFAEQYVHGALGRIELFKGERPLFETHNVEQEISRALQPRVNLNFGSYLIIESTEAMTT 322 Query: 301 IDVNTGSFVNGRNFDDTIFKTNLEAAHAIARQLRLRNLGGIIILDFIDMESTEHRQAVLA 360 IDVNTG FV RNFD+TIF+TNLEA H IAR+LRLRNLGGIII+DFIDM HR+AVL Sbjct: 323 IDVNTGGFVGARNFDETIFRTNLEACHTIARELRLRNLGGIIIIDFIDMAQESHREAVLQ 382 Query: 361 ELGKALQRDRTKISVSGFSTLGLVEMTRKRTRESLAHILCETCPACKGRGQVKTSRTVCY 420 EL KAL DRT++++ GF++LGLVE+TRKR+RE+L +LCE CP+C+GRG++KT +TVCY Sbjct: 383 ELAKALAFDRTRVTLHGFTSLGLVELTRKRSRENLNQVLCEPCPSCQGRGRLKTPQTVCY 442 Query: 421 EILREVMREAKQFNPREFRILASQVVVDMFLEEESQHLAMLGDFIGKPISLQVQSDYQQE 480 EI RE++REA++++ FRILA+ V+D+FL+EESQ LAML DFIGKPISL V++ Y QE Sbjct: 443 EIQREIVREARRYDAESFRILAAPNVIDLFLDEESQSLAMLIDFIGKPISLAVETAYTQE 502 Query: 481 QYDIILM 487 QYDI+LM Sbjct: 503 QYDIVLM 509 >PA4477 [J] COG1530 Ribonucleases G and E Pae Pseudomonas aeruginosa Length = 485 Score = 545 bits (1405), Expect = e-155, Method: Compositional matrix adjust. Identities = 281/490 (57%), Positives = 360/490 (73%), Gaps = 8/490 (1%) Query: 1 MSEDILINITPQETRVALILQGAVQELHIERTLSRGLAGNIYLGKVVRVLPGMQSAFIDI 60 MSE+ILINITP E+RVA++ G +QE+H+ERT RG+ GNIY G+VVRVLPGMQ+AF+DI Sbjct: 1 MSEEILINITPMESRVAVVENGVLQEVHVERTQRRGIVGNIYKGRVVRVLPGMQAAFVDI 60 Query: 61 GLERAAFLHVADIWEARPHDGQNAPAIPIEKLLHDGQTITVQVIKDPIGTKGARLSTQIS 120 GLERAAF+H A+I + + + I L+H+GQ + VQV KDPIGTKGARL+T +S Sbjct: 61 GLERAAFIHAAEI-----SNREGSAVESISALVHEGQALVVQVTKDPIGTKGARLTTHLS 115 Query: 121 IAGRMLVYLPQDKHIGISQRIENEAERELLRSKVQALLPPEE---KGGFIIRTMAEDASD 177 I R LVY+P+ H+GIS RIE+E ERE L+ V + E +GGFI+RT AE A + Sbjct: 116 IPSRYLVYMPRTSHVGISLRIEDEVERERLKKVVADCVAAEGIEGQGGFILRTAAEGAGE 175 Query: 178 ADLQMDVEYLRTTWATITKQAKTKPAPTLLHQDLSLAQRVLRDFVSDHTATIQVDSRENF 237 ++ D+ YLR W I Q +T AP+++++DLSLA R LRD V+ I++DSRENF Sbjct: 176 DEILADIRYLRRLWDQIAAQIQTVGAPSVIYEDLSLAIRTLRDLVNPRIEKIRIDSRENF 235 Query: 238 HMLQEFGAIYTPSVLTKLMHYRGERPLFDLYGVEEEIERALGRRVDLKSGGYLIVDQTEA 297 + F P + +L HY GERP+FDLYGVE+EI++AL R+V LKSGGYLIVD TEA Sbjct: 236 QKITSFVEELMPEISDRLEHYPGERPIFDLYGVEDEIQKALERKVLLKSGGYLIVDPTEA 295 Query: 298 MTTIDVNTGSFVNGRNFDDTIFKTNLEAAHAIARQLRLRNLGGIIILDFIDMESTEHRQA 357 MTTIDVNTG+FV RN ++TIFKTNLEAA AIARQLRLRNLGGIII+DFIDME EHR+ Sbjct: 296 MTTIDVNTGAFVGHRNLEETIFKTNLEAATAIARQLRLRNLGGIIIIDFIDMEDEEHRRQ 355 Query: 358 VLAELGKALQRDRTKISVSGFSTLGLVEMTRKRTRESLAHILCETCPACKGRGQVKTSRT 417 VL L K L+RD K ++ G + LGLV+MTRKRTRESL ILCE CP C+GRG +KT+ T Sbjct: 356 VLRTLEKQLERDHAKTNIIGITELGLVQMTRKRTRESLVQILCEPCPCCQGRGMLKTAET 415 Query: 418 VCYEILREVMREAKQFNPREFRILASQVVVDMFLEEESQHLAMLGDFIGKPISLQVQSDY 477 CYEI RE++REA+ + + +LA+Q VVD L+EES ++A L FIG+ I QV++ Y Sbjct: 416 TCYEIFREILREARAYQADSYLVLANQKVVDRLLDEESGNVADLEAFIGRTIKFQVEAMY 475 Query: 478 QQEQYDIILM 487 QEQYD++L+ Sbjct: 476 SQEQYDVVLL 485 >VC0419 [J] COG1530 Ribonucleases G and E Vch Vibrio cholerae Length = 489 Score = 519 bits (1336), Expect = e-147, Method: Compositional matrix adjust. Identities = 265/494 (53%), Positives = 350/494 (70%), Gaps = 12/494 (2%) Query: 1 MSEDILINITPQETRVALILQGAVQELHIERTLSRGLAGNIYLGKVVRVLPGMQSAFIDI 60 MS ++L+N+TP ETRVA+I G +QE+HIER RG+ GNIY GKV RVLPGMQ+AF+DI Sbjct: 1 MSAELLLNVTPSETRVAMIEGGILQEIHIEREAKRGIVGNIYKGKVSRVLPGMQAAFVDI 60 Query: 61 GLERAAFLHVADIWEARPH-------DGQNAPAIPIEKLLHDGQTITVQVIKDPIGTKGA 113 GL++AAFLH +DI PH + Q I +L+ GQ I VQV+KDP+GTKGA Sbjct: 61 GLDKAAFLHASDIV---PHTECVAESEKQQFQVRDISELVRQGQDIVVQVVKDPLGTKGA 117 Query: 114 RLSTQISIAGRMLVYLPQDKHIGISQRIENEAERELLRSKVQALLPPEEKGGFIIRTMAE 173 RL+T I++ R LV++P H+G+SQRIE+EAERE L+ V +E GGFIIRT AE Sbjct: 118 RLTTDITLPSRYLVFMPGASHVGVSQRIESEAERERLKKIVSHYC--DEHGGFIIRTAAE 175 Query: 174 DASDADLQMDVEYLRTTWATITKQAKTKPAPTLLHQDLSLAQRVLRDFVSDHTATIQVDS 233 A++ +L D +L+ W+ + ++ ++L+ +L LAQR+LRDFV I +DS Sbjct: 176 GANEKELTQDAAFLKRLWSKVIERRSKYKNRSMLYGELGLAQRILRDFVGTELTKILIDS 235 Query: 234 RENFHMLQEFGAIYTPSVLTKLMHYRGERPLFDLYGVEEEIERALGRRVDLKSGGYLIVD 293 R+ F L+EF + Y P + KL Y G++P+FD+Y E EI+R+L R+V+LKSGGYLI+D Sbjct: 236 RQEFENLKEFTSEYVPELTAKLELYHGDKPIFDMYDTENEIQRSLERKVELKSGGYLIID 295 Query: 294 QTEAMTTIDVNTGSFVNGRNFDDTIFKTNLEAAHAIARQLRLRNLGGIIILDFIDMESTE 353 QTEAMTTID+NTG+FV RN ++TIF TN+EA AIARQLRLRNLGGIII+DFIDM S E Sbjct: 296 QTEAMTTIDINTGAFVGRRNLEETIFNTNIEATQAIARQLRLRNLGGIIIIDFIDMASDE 355 Query: 354 HRQAVLAELGKALQRDRTKISVSGFSTLGLVEMTRKRTRESLAHILCETCPACKGRGQVK 413 HR+ VL L AL +DR K +++GF+ LGLVEMTRKRTRES+ H+LC TCP C+GRG VK Sbjct: 356 HRKRVLTSLETALMKDRVKTNINGFTQLGLVEMTRKRTRESIEHVLCSTCPTCEGRGSVK 415 Query: 414 TSRTVCYEILREVMREAKQFNPREFRILASQVVVDMFLEEESQHLAMLGDFIGKPISLQV 473 T TVC+EILRE+ R + ++ +F + AS V D EES LA L FIGK + +Q Sbjct: 416 TVETVCFEILREITRVNRAYDADKFVVYASPAVADTLQGEESHALAELEVFIGKEVRIQA 475 Query: 474 QSDYQQEQYDIILM 487 + Y QEQ+D+++M Sbjct: 476 EPLYNQEQFDVVMM 489