BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.3442.p (454 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value atoE [I] COG2031 Short chain fatty acids transporter Eco Escheri... 291 2e-78 HI0772 [I] COG2031 Short chain fatty acids transporter Hin Haemo... 278 1e-74 FN1858 [I] COG2031 Short chain fatty acids transporter Fnu Fusob... 266 6e-71 BH0358 [I] COG2031 Short chain fatty acids transporter Bha Bacil... 254 3e-67 jhp0635 Non COG 240 5e-63 >atoE [I] COG2031 Short chain fatty acids transporter Eco Escherichia coli K12 Length = 440 Score = 291 bits (745), Expect = 2e-78, Method: Compositional matrix adjust. Identities = 164/442 (37%), Positives = 253/442 (57%), Gaps = 11/442 (2%) Query: 15 LTEMTIRLFERMIPDPFVLAILITALVTLLSFLFAPHATLAHVIGGWYKGYFDILTFAFQ 74 ++ R R +PDP + A+L+T L +++ P ++ ++ W G++++L F Q Sbjct: 5 ISRFMTRFVSRWLPDPLIFAMLLTLLTFVIALWLTPQTPIS-MVKMWGDGFWNLLAFGMQ 63 Query: 75 ITLILVTGHAFAHAPPVQRCFKALVGLANTPAQAATLTFLSVAVASFFNWGFGLVVSALL 134 + LI+VTGHA A + PV+ + A TP Q L +VA NWGFGLVV A+ Sbjct: 64 MALIIVTGHALASSAPVKSLLRTAASAAKTPVQGVMLVTFFGSVACVINWGFGLVVGAMF 123 Query: 135 AREVAKRMR-VDFAWIVAAGYSGWVVWATGVSSSIALAQSTPGSAMNIVEKLTGQVLPFS 193 AREVA+R+ D+ ++A Y G++ W G S S+ L +TPG N VE + G ++P Sbjct: 124 AREVARRVPGSDYPLLIACAYIGFLTWGGGFSGSMPLLAATPG---NPVEHIAG-LIPVG 179 Query: 194 STVFTRFNIIPTVIMLVAMPVVLAWLKPNDEQSSVLDIENN---PDAPIRQKPTGKLSFA 250 T+F+ FNI TV ++V MP + + P + S V+ I+ +A +++ + Sbjct: 180 DTLFSGFNIFITVALIVVMPFITRMMMP--KPSDVVSIDPKLLMEEADFQKQLPKDAPPS 237 Query: 251 AWIEHSWIGSAFIGLVGIGLLVLSQFQHIAFSGVNAVIFVMFIAGVLLHGYPLAYADAVK 310 +E S I + IG +GI L + +H +N V + IAG+LLH P+AY A+ Sbjct: 238 ERLEESRILTLIIGALGIAYLAMYFSEHGFNITINTVNLMFMIAGLLLHKTPMAYMRAIS 297 Query: 311 NAAKQTGSMMLQYPLYGGIMGIMDATGLPDVIAHFFITISNAHTLPFWSYVCSLIVTFFI 370 AA+ T +++Q+P Y GI +M+ +GL +I FFI ++N T P ++ S ++ F + Sbjct: 298 AAARSTAGILVQFPFYAGIQLMMEHSGLGGLITEFFINVANKDTFPVMTFFSSALINFAV 357 Query: 371 PSGGGHWAVQGPFVVPAAVALHASVPATTMAVAMGEQVSNMLQPFWAAPVVAMAGIGVQR 430 PSGGGHW +QGPFV+PAA AL A + + MA+A GEQ NM QPFWA P +A+AG+GV+ Sbjct: 358 PSGGGHWVIQGPFVIPAAQALGADLGKSVMAIAYGEQWMNMAQPFWALPALAIAGLGVRD 417 Query: 431 VLGYTATTFLVGAVVYGAALLL 452 ++GY T L V++ L L Sbjct: 418 IMGYCITALLFSGVIFVIGLTL 439 >HI0772 [I] COG2031 Short chain fatty acids transporter Hin Haemophilus influenzae Length = 447 Score = 278 bits (712), Expect = 1e-74, Method: Compositional matrix adjust. Identities = 147/435 (33%), Positives = 250/435 (57%), Gaps = 6/435 (1%) Query: 24 ERMIPDPFVLAILITALVTLLSFLFAPHATLAHVIGGWYKGYFDILTFAFQITLILVTGH 83 + +PDP + A+L+T VT + +T ++ W G++++L F Q+ LI+VTG+ Sbjct: 14 SKYLPDPLIFAVLLT-FVTFICAWGLTDSTPVDLVNMWGNGFWNLLGFGMQMALIVVTGN 72 Query: 84 AFAHAPPVQRCFKALVGLANTPAQAATLTFLSVAVASFFNWGFGLVVSALLAREVAKRMR 143 A A +P +++ + +A TPAQ L ++A NWGFGLVV A+ A+EVA+R++ Sbjct: 73 ALATSPQIRKFLSTIASIAKTPAQGVVLVTFMGSIACIINWGFGLVVGAMFAKEVARRIK 132 Query: 144 -VDFAWIVAAGYSGWVVWATGVSSSIALAQSTPGSA---MNIVEKLTGQVLPFSSTVFTR 199 D+A ++A Y ++ W G S S+ L +TPG+ + + E ++P ST+F+ Sbjct: 133 GSDYALLIACAYIAFMTWGGGFSGSMPLLAATPGNPVAHLMMSESNPQGIIPAVSTLFSG 192 Query: 200 FNIIPTVIMLVAMPVVLAWLKPNDEQSSVLDIE-NNPDAPIRQKPTGKLSFAAWIEHSWI 258 +NI T+ +++ +P + + P + ++ +D + PD +K + A +E S Sbjct: 193 YNIFITLSLVICLPFITYMMMPKNGETKSIDPKLIAPDPTFDKKLDKDATLAEKMEESRF 252 Query: 259 GSAFIGLVGIGLLVLSQFQHIAFSGVNAVIFVMFIAGVLLHGYPLAYADAVKNAAKQTGS 318 + IG +G L + +++ +N V + I G++LHG P+AY A+ NA + T Sbjct: 253 LAYTIGALGYSYLGMYFYKNGFNLTINNVNLIFLITGIVLHGSPMAYMRAIINATRSTAG 312 Query: 319 MMLQYPLYGGIMGIMDATGLPDVIAHFFITISNAHTLPFWSYVCSLIVTFFIPSGGGHWA 378 +++Q+P Y G+ +M+ +GL +I FFI ++N + P ++ S + F +PSGGGHW Sbjct: 313 ILVQFPFYAGVQLMMEHSGLGGLITEFFINVANKDSFPLLTFFSSAFINFAVPSGGGHWV 372 Query: 379 VQGPFVVPAAVALHASVPATTMAVAMGEQVSNMLQPFWAAPVVAMAGIGVQRVLGYTATT 438 +QGPFV+PAA AL A + +TMA+A GEQ NM QPFWA P + +AG+GV+ ++G+ T Sbjct: 373 IQGPFVIPAAQALGADLGKSTMAIAYGEQWMNMAQPFWALPALGIAGLGVRDIMGFCMTA 432 Query: 439 FLVGAVVYGAALLLL 453 + A ++ L L Sbjct: 433 LIFTAPIFIIGLYFL 447 >FN1858 [I] COG2031 Short chain fatty acids transporter Fnu Fusobacterium nucleatum Length = 458 Score = 266 bits (681), Expect = 6e-71, Method: Compositional matrix adjust. Identities = 152/461 (32%), Positives = 255/461 (55%), Gaps = 21/461 (4%) Query: 7 SASRRK---TSLTEMTIRLFERMIPDPFVLAILITALVTLLSFLFAPHATLAHVIGGWYK 63 S RK T M +R+ ER +PDPF+ L+T + + +F AT V+G W Sbjct: 3 SVKERKGIFKRFTSMCVRVMERWLPDPFIFCALLT-FIVFIGAIFLTKATPLQVVGFWAD 61 Query: 64 GYFDILTFAFQITLILVTGHAFAHAPPVQRCFKALVGLANTPAQAATLTFLSVAVASFFN 123 G++ +L+F+ Q+ L+LVTGH A + ++ P QA + + +A N Sbjct: 62 GFWSLLSFSMQMALVLVTGHTLASSRLFKKMLSTFASGIKGPKQAILIVSIVSGIACALN 121 Query: 124 WGFGLVVSALLAREVAKRMR-VDFAWIVAAGYSGWVVWATGVSSSIALAQSTPGSAM-NI 181 WGFGLV+ AL A+E+AK+++ VD+ ++A+ Y+G++VW G+S SI L ++ G + Sbjct: 122 WGFGLVIGALFAKEIAKKVKGVDYRLLIASAYTGFLVWHGGLSGSIPLQLASGGEGLAKQ 181 Query: 182 VEKLTGQVLPFSSTVFTRFNIIPTVIMLVAMPVVLAWLKPNDEQSSVLDIENNPDAPIRQ 241 + + +P S T+F+ NI V +L+ +P++ + P+ ++ +E +P + Sbjct: 182 TAGVVTEAIPTSQTLFSPMNIFIIVGLLIIVPLLNMAMFPSKDEI----VEVDPKLLVEP 237 Query: 242 KP----TGKLSFAAWIEHSWIGSAFIGLVGIGLLVLSQFQHIAFS-GVNAVIFVMFIAGV 296 + T K++ A +E+S S + ++G + + + F+ +N V F+ G+ Sbjct: 238 EEVVMDTSKMTPAERVENSSAVSILLSIMGF-VYIGYYLKTKGFALNLNLVNFIFLFLGI 296 Query: 297 LLHGYPLAYADAVKNAAKQTGSMMLQYPLYGGIMGIM-----DATGLPDVIAHFFITISN 351 LLHG P Y +A+ A K G ++LQ+P Y GIMGIM D L ++++FF++IS Sbjct: 297 LLHGTPRRYLNALAEATKGAGGILLQFPFYAGIMGIMVGADADGMSLAKLMSNFFVSIST 356 Query: 352 AHTLPFWSYVCSLIVTFFIPSGGGHWAVQGPFVVPAAVALHASVPATTMAVAMGEQVSNM 411 T P +S++ + +V FF+PSGGG WAVQ P V+PA A+ S + MA+A G+ +NM Sbjct: 357 EKTFPVFSFISAGVVNFFVPSGGGQWAVQAPIVMPAGQAIGVSAAKSAMAIAWGDAWTNM 416 Query: 412 LQPFWAAPVVAMAGIGVQRVLGYTATTFLVGAVVYGAALLL 452 +QPFWA P + +AG+G + ++GY +V + LL Sbjct: 417 IQPFWALPALGIAGLGAKDIMGYCLIVTVVSGIFICTGFLL 457 >BH0358 [I] COG2031 Short chain fatty acids transporter Bha Bacillus halodurans Length = 441 Score = 254 bits (649), Expect = 3e-67, Method: Compositional matrix adjust. Identities = 150/446 (33%), Positives = 254/446 (56%), Gaps = 15/446 (3%) Query: 15 LTEMTIRLFERMIPDPFVLAILITALVTLLSFLFAPHATLAHVIGGWYKGYFDILTFAFQ 74 + ++ RL +R +PDPF+ +L+T LV LS +F L ++ W +G++ +L+F+ Q Sbjct: 4 MISLSNRLMQRYLPDPFLFVVLLTFLVFALSLIFTESTPLT-IVQYWGEGFWGLLSFSMQ 62 Query: 75 ITLILVTGHAFAHAPPVQRCFKALVGLANTPAQAATLTFLSVAVASFFNWGFGLVVSALL 134 + L+LVTGH A +P ++ AL GL +P QA L + VASF NWGFGLV+ AL Sbjct: 63 MVLVLVTGHVLASSPLFKKGLGALAGLPASPGQAILLVTVVSLVASFINWGFGLVIGALF 122 Query: 135 AREVAKRM-RVDFAWIVAAGYSGWVVWATGVSSSIALAQSTPGSAMNIVEKLTGQVLPFS 193 A+E+AK++ VD+ ++A+ YSG+++W G+S S+ L +TP + + + G V+P S Sbjct: 123 AKELAKKVDNVDYRLLIASAYSGFMIWHGGLSGSVPLTIATPD---HFAQDMIG-VIPTS 178 Query: 194 STVFTRFNIIPTVIMLVAMPVVLAWLKPNDEQSSVLD---IENNPDAPIRQKPTGKLSFA 250 T+F +N+ + +A+P+ + P + +D +++ D ++ + Sbjct: 179 ETIFAPYNLAIVFALFIAIPLANRLMMPGKSDTVTVDRSLLDDGRDLQAASLELEAMTPS 238 Query: 251 AWIEHSWIGSAFIGLVGI---GLLVLSQFQHIAFSGVNAVIFVMFIAGVLLHGYPLAYAD 307 +E+S + S +G++G+ G + + VN++ + G+L HG P + Sbjct: 239 DRLENSRMISLLVGVLGLVFLGYYFATNGFELNLDIVNSLFLFL---GILFHGTPKLFLK 295 Query: 308 AVKNAAKQTGSMMLQYPLYGGIMGIMDATGLPDVIAHFFITISNAHTLPFWSYVCSLIVT 367 AV +A K +++Q+P Y G+MGIM ++GL V++ F++ SN T P + ++ + IV Sbjct: 296 AVTSAVKGASGIIIQFPFYAGLMGIMVSSGLATVMSEAFVSFSNEVTFPLFVFLSAGIVN 355 Query: 368 FFIPSGGGHWAVQGPFVVPAAVALHASVPATTMAVAMGEQVSNMLQPFWAAPVVAMAGIG 427 F+PSGGG WAVQ P V+ AA +L MAVA G+ +NM+QPFWA P +A+AG+ Sbjct: 356 VFVPSGGGQWAVQAPVVLEAAQSLGVPAAKAAMAVAWGDAWTNMIQPFWALPALAIAGLK 415 Query: 428 VQRVLGYTATTFLVGAVVYGAALLLL 453 + ++G+ +V VV LL+ Sbjct: 416 AKDIMGFCVMILVVSGVVISLGFLLM 441 >jhp0635 Non COG Length = 454 Score = 240 bits (613), Expect = 5e-63, Method: Compositional matrix adjust. Identities = 157/447 (35%), Positives = 252/447 (56%), Gaps = 19/447 (4%) Query: 15 LTEMTIRLFERMIPDPFVLAILITALVTLLSFLFAPHATLAHVIGGWYKGYFDILTFAFQ 74 LT + L + +PD FVL L++ +V +L + + VI W G + +L F+ Q Sbjct: 7 LTSACVFLASKCLPDSFVLVALLSFVVFVLVYCLTGQDA-SSVISSWGNGAWTLLGFSMQ 65 Query: 75 ITLILVTGHAFAHAPPVQRCFKALVGLANTPAQAATL-TFLSVAVASFFNWGFGLVVSAL 133 + LILV G A A A VQ+ K L L A L TFLS+ +A++ NWGFGLV+SA+ Sbjct: 66 MALILVLGQALASAKLVQKLLKYLASLPKGYYTALWLVTFLSL-IANWINWGFGLVISAI 124 Query: 134 LAREVAKRMR-VDFAWIVAAGYSGWVVWATGVSSSIALAQSTPGSAMN-IVEKLTGQVLP 191 A+E+AK ++ VD+ ++A+ YSG+V+W G+S SI L+ +T ++ I + + +P Sbjct: 125 FAKEIAKNVKGVDYRLLIASAYSGFVIWHGGLSGSIPLSVATQNENLSKISAGVIEKAIP 184 Query: 192 FSSTVFTRFNIIPTVIMLVAMPVVLAWLKPNDEQ-----SSVLDIENNPDAPIRQKPTGK 246 S T+F+ +N+I I+L+ +P ++A + P E+ S +L E I + Sbjct: 185 ISQTIFSSYNLIIIGIILIGLPFLMAMIHPKKEEIVEIDSKLLKDEYKETELISHQQDK- 243 Query: 247 LSFAAWIEHSWIGSAFIGLVGIGLLVLSQFQHIAFSGVNAVIFVMFIAGVLLHGYPLAYA 306 + A ++E+S + S + +G G L + F+ S +N V + G+LLH PLAY Sbjct: 244 -TIAHFLENSALLSYLLVFLGFGYLGIYFFKGGGIS-LNIVNTIFLFLGILLHKTPLAYV 301 Query: 307 DAVKNAAKQTGSMMLQYPLYGGIMGIM-----DATGLPDVIAHFFITISNAHTLPFWSYV 361 A+ ++A+ ++LQ+P Y GIMG+M L +++ F I+N T +++ Sbjct: 302 KAINHSARSVAGILLQFPFYAGIMGMMASHSVGGHSLAQMLSLAFTHIANEKTFALMTFL 361 Query: 362 CSLIVTFFIPSGGGHWAVQGPFVVPAAVALHASVPATTMAVAMGEQVSNMLQPFWAAPVV 421 + IV FIPSGGG WA+Q P ++PA +L +MA+A G+ +NM+QPFWA P + Sbjct: 362 SAGIVNIFIPSGGGQWAIQAPIMLPAGQSLGVDPGVISMAIAWGDAWTNMIQPFWALPAL 421 Query: 422 AMAGIGVQRVLGYTATTFL-VGAVVYG 447 A+AG+G + ++GY T + VG VV G Sbjct: 422 AIAGLGAKDIMGYCVLTLIFVGLVVCG 448