BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.3421.p (1351 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1251 [L] COG1643 HrpA-like helicases Rso Ralstonia solanacearum 1781 0.0 STM1641 [L] COG1643 HrpA-like helicases Sty Salmonella typhimuri... 1140 0.0 hrpA [L] COG1643 HrpA-like helicases Eco Escherichia coli K12 1129 0.0 ZhrpA [L] COG1643 HrpA-like helicases EcZ Escherichia coli O157:... 1125 0.0 ECs2015 [L] COG1643 HrpA-like helicases Ecs Escherichia coli O15... 1125 0.0 >RSc1251 [L] COG1643 HrpA-like helicases Rso Ralstonia solanacearum Length = 1331 Score = 1781 bits (4613), Expect = 0.0, Method: Compositional matrix adjust. Identities = 923/1372 (67%), Positives = 1065/1372 (77%), Gaps = 76/1372 (5%) Query: 9 TPPGAQPQQTPQQDRGRGPREP-------RGPRRAEPA-------SEAAPPVRNPLPPVT 54 +PP A P Q+ D R R+ R PRR +P EA N +PP++ Sbjct: 7 SPPSAAPSQSSPNDASRPARQAGQADAGGRRPRRQKPTPEALAAALEARRARANAVPPIS 66 Query: 55 FPEELPVSGRRHEIAEALRRHQVIIVSGETGSGKTTQLPKICLELGRGAKG----LIGHT 110 FPE LPVS RR EIA A+ HQV+IVSGETGSGKTTQLPKICL +GRG LIGHT Sbjct: 67 FPEALPVSARRDEIARAVAAHQVVIVSGETGSGKTTQLPKICLSIGRGIGAGGTGLIGHT 126 Query: 111 QPRRIAASSTAKRIAQELNSPPGELVGYKVRFNDTLSKGAWIKLMTDGILLAETQTDPLL 170 QPRRIAA+STAKRIAQE+ SP GE VGY+VRFNDTLS GA +KLMTDGILLAETQ DPLL Sbjct: 127 QPRRIAATSTAKRIAQEIGSPLGEHVGYQVRFNDTLSAGASVKLMTDGILLAETQNDPLL 186 Query: 171 RQYDTIIIDEAHERSLNIDFLLGYLKQLLPKRPDLKIIITSATIDADRFARHFGRELKGE 230 R YDTIIIDEAHERSLNIDFLLGYLKQLLP+RPDLK+IITSATIDA RFA HF G Sbjct: 187 RGYDTIIIDEAHERSLNIDFLLGYLKQLLPRRPDLKVIITSATIDAQRFAEHFA----GP 242 Query: 231 LVPAPVIEVSGRLYPVEIRYRPIDNADRSGVSTEVAQARARAEGRASQAQKDREQRDLMD 290 PAPVIEVSGRLYPVE+RYRP+ + +KD+E RDL D Sbjct: 243 KGPAPVIEVSGRLYPVEVRYRPV-----------------------QRDEKDKE-RDLYD 278 Query: 291 AVVDAVDELARIGSGDVLVFLPGEREIRDAAEALRKHHPPHVEILPLFARLSAQEQERVF 350 +VDAVDELAR G+GDVL+FLPGEREIR+AAEALRKHHP H EILPLFARLS QEQERVF Sbjct: 279 GIVDAVDELAREGAGDVLIFLPGEREIREAAEALRKHHPAHTEILPLFARLSVQEQERVF 338 Query: 351 KTSNARRIVLATNVAETSLTVPGIRYVVDAGLARVKRYSYRNKVEQLQIEPVAQSAANQR 410 + SNARRIVLATNVAETSLTVPGIRYVVDAGLARVKRYSYRNKVEQLQIEPV+Q+AANQR Sbjct: 339 RPSNARRIVLATNVAETSLTVPGIRYVVDAGLARVKRYSYRNKVEQLQIEPVSQAAANQR 398 Query: 411 AGRCGRVAAGVCIRLYDEQDFLQRPKFTDPEILRSSLASVILRMKSLHLTDVESFPFIEP 470 AGRCGRVA GVCIRLY+E DF+ RP+FTDPEILRSSLA+VILRMK+L LTDVE FPFIEP Sbjct: 399 AGRCGRVADGVCIRLYEEADFIARPRFTDPEILRSSLAAVILRMKALRLTDVEQFPFIEP 458 Query: 471 PLGRAIADGYQLLQELGAVEEQGGVNRLTPLGKQLARLPLDPRVGRMILAGRDNACLTEL 530 PLGRAIADGYQLLQELGAV+++ N LTPLGKQ+ARLPLDPRV RMILAGRD+ CL E+ Sbjct: 459 PLGRAIADGYQLLQELGAVDDE---NALTPLGKQVARLPLDPRVARMILAGRDHQCLREM 515 Query: 531 LIIAAAVSVQDPRDRPMDAQNAADNAHKKFADEKSEFASYLKIWKWFEDAIAHKKSNRQL 590 LIIA+A+SVQDPRDRP + Q AD AH++FADEKSEF ++K+WKWFE+A+AHKKSN+QL Sbjct: 516 LIIASALSVQDPRDRPQELQQQADQAHRQFADEKSEFLGWVKLWKWFEEAVAHKKSNKQL 575 Query: 591 QEHCRENFLSQLRLREWRDVHSQLLTIVKEQGWRLNEAAATYDQLHLALLTGLLGNVGFK 650 Q+ CR +FLS LRLREWRDVHSQL T V EQGW+LNE+ TY+QLHLALLTGLLGN+G + Sbjct: 576 QDQCRAHFLSHLRLREWRDVHSQLHTTVAEQGWKLNESEPTYEQLHLALLTGLLGNIGVR 635 Query: 651 SDD----DAQYLGARGIKFNIWPGAHLTKKPGRWVMAAELVDTARLYARCVANIQPEWLE 706 ++ +YLGARGIKF +WPG+ + +K G+W++A EL++T+RL+ R +A I+PEW+E Sbjct: 636 IEEADGKGREYLGARGIKFFLWPGSAIARKAGKWMVAGELIETSRLFGRTLARIEPEWVE 695 Query: 707 KLGGHLLKKSWGEPRWEKRAAQVTASERATLYGLVVYSQRRINYGNINPVEAREIFIRDA 766 K+G HLLK SW +P WEK+A QV A ER TLYGL VY QRR+++G + P EARE+FIR A Sbjct: 696 KVGAHLLKVSWSDPHWEKKAGQVMAFERGTLYGLPVYQQRRVHFGPMQPREARELFIRRA 755 Query: 767 LVGGDFETRAPFFAHNQKLVREIENLEHKSRRLDVLVDDELIIGFYDKLIPQDICNGVDF 826 LV G+FETR PFFAHNQ+LVREIENLEHKSRR DVLVDDELI FYD IP DI N V F Sbjct: 756 LVDGEFETRLPFFAHNQRLVREIENLEHKSRRQDVLVDDELIHAFYDSQIPADIHNTVAF 815 Query: 827 EKWHKQATAADPKLLYLNRDDLMRHEAAGVTTELFPKTMNVAGIAMALSYHFEPGAARDG 886 E W+ +A A KLLYLNRDDLMRHEAAG+TT+LFPKT+ +AGI M L+YHFEPG+ RDG Sbjct: 816 EGWYAEAAKASQKLLYLNRDDLMRHEAAGITTDLFPKTLPIAGIDMGLTYHFEPGSPRDG 875 Query: 887 VTLTVPLYALNQVSADRCEWLVPGMLKEKVHLLLKSLPQKLRRHCVPLPDYAARFCERME 946 VTLTVPLYALNQV A R EWLVPGMLKEK HLLLKSLPQKLRRHCVPLPDYAA F R+ Sbjct: 876 VTLTVPLYALNQVPAQRAEWLVPGMLKEKAHLLLKSLPQKLRRHCVPLPDYAAGFVSRVR 935 Query: 947 ERKTFGRGNLIDAIIADIREQITLLVKPSDFKQETLSAHHAMNFKIVDEHGRQLEMGRNL 1006 G G+L+D +IAD+REQ +K +DFK ETL AHH MNFK++DEHGRQL+MGRNL Sbjct: 936 ----LGDGDLLDRLIADVREQTGTPLKRADFKLETLPAHHFMNFKVIDEHGRQLDMGRNL 991 Query: 1007 AALQAEFGGQARQQFQKLAEQVAIAPREDEDSAAPLPAAAAGKGGATIATPAAPASVGEY 1066 A L+AE GG+A+Q FQ +A + A D A P GKGG P APA+ Y Sbjct: 992 AQLRAELGGRAQQTFQSIAAKDAAVAGAPGDGAGARP----GKGG----KPDAPANPALY 1043 Query: 1067 SNLTSWSFGELPELLEITRGSGKQAQTLIGFPALVDRLTHCDLEVFDDPTEAARFHYAGL 1126 S LT+W+FGELPELLE+ +GS QTL G+PALVD HCD+EVFDDP EAAR H GL Sbjct: 1044 SGLTTWNFGELPELLEVRKGS----QTLFGYPALVDGGDHCDVEVFDDPAEAARIHRLGL 1099 Query: 1127 RRLFALQMKEQLKYLEKNIPGLQQMGMQFMALGTQEELREQILNAGLERAFLQDPLPRNA 1186 RRLFALQ++E LKYLEKNIPGL QM +QFM LG Q+ELR QIL+A L+RA LQDPLP + Sbjct: 1100 RRLFALQLREPLKYLEKNIPGLSQMAIQFMTLGAQDELRNQILDAALDRACLQDPLPADD 1159 Query: 1187 DEFNRRRDEGKARLGLLVNEIARLCGLILAEYHSLPKKLQGIKAHAQAAADMQAQLSQLV 1246 F R+DEG+ RL LL EIARL G ILAEY LP+KLQ K A AD+ AQL L+ Sbjct: 1160 AGFGARKDEGRTRLTLLAQEIARLAGAILAEYAQLPRKLQIAKPFGAAYADIDAQLKALM 1219 Query: 1247 GKRFVAETDYGNLSHYPRYLKAINVRLDKLRADPARDTRLLAEWNSVALPYQRGLKD--- 1303 KRF+ T Y L+H+PRYLK I +R+DKL+ADP RDT+ + E + YQR K Sbjct: 1220 HKRFIEATPYAQLAHFPRYLKGIAMRIDKLKADPTRDTQRMQEMAPLFQQYQRAEKQLRV 1279 Query: 1304 ----RAGRADPKMTEFRWMLEELRVSLYAQELKTPMPVSVKRLQKVWESMQR 1351 RA DP+M EFRWMLEELR++L+AQEL+TP+P+SVKRLQKVWESMQR Sbjct: 1280 QGQGRAAAGDPRMEEFRWMLEELRIALFAQELRTPVPMSVKRLQKVWESMQR 1331 >STM1641 [L] COG1643 HrpA-like helicases Sty Salmonella typhimurium LT2 Length = 1300 Score = 1140 bits (2950), Expect = 0.0, Method: Compositional matrix adjust. Identities = 598/1299 (46%), Positives = 837/1299 (64%), Gaps = 83/1299 (6%) Query: 51 PPVTFPEELPVSGRRHEIAEALRRHQVIIVSGETGSGKTTQLPKICLELGRGAKGLIGHT 110 P +T+P+ LPVS ++ +I EA+R HQV+IV+GETGSGKTTQLPKIC+ELGRG KGLIGHT Sbjct: 69 PSITYPQNLPVSQKKQDILEAIRDHQVVIVAGETGSGKTTQLPKICMELGRGIKGLIGHT 128 Query: 111 QPRRIAASSTAKRIAQELNSPPGELVGYKVRFNDTLSKGAWIKLMTDGILLAETQTDPLL 170 QPRR+AA + A RIA+EL + PG +GYKVRF+D +S +KLMTDGILLAE Q D LL Sbjct: 129 QPRRLAARTVANRIAEELQTEPGGCIGYKVRFSDHVSSNTMVKLMTDGILLAEIQQDRLL 188 Query: 171 RQYDTIIIDEAHERSLNIDFLLGYLKQLLPKRPDLKIIITSATIDADRFARHFGRELKGE 230 QYDT+IIDEAHERSLNIDFLLGYLK+LLP+RPDLK+IITSATID +RF+RHF Sbjct: 189 MQYDTLIIDEAHERSLNIDFLLGYLKELLPRRPDLKVIITSATIDPERFSRHFNN----- 243 Query: 231 LVPAPVIEVSGRLYPVEIRYRPIDNADRSGVSTEVAQARARAEGRASQAQKDREQRDLMD 290 AP+IEVSGR YPVE+RYRPI V +A D +RD + Sbjct: 244 ---APIIEVSGRTYPVEVRYRPI-----------VEEA-------------DDTERDQLQ 276 Query: 291 AVVDAVDELARIGSGDVLVFLPGEREIRDAAEALRKHHPPHVEILPLFARLSAQEQERVF 350 A+ DAVDEL R GD+L+F+ GEREIRD A+AL K + H E+LPL+ARLS EQ RVF Sbjct: 277 AIFDAVDELGRESPGDILIFMSGEREIRDTADALNKLNLRHTEVLPLYARLSNSEQNRVF 336 Query: 351 KTSNARRIVLATNVAETSLTVPGIRYVVDAGLARVKRYSYRNKVEQLQIEPVAQSAANQR 410 ++ + RRIVLATNVAETSLTVPGI+YV+D G AR+ RYSYR KV++L IEP++Q++ANQR Sbjct: 337 QSHSGRRIVLATNVAETSLTVPGIKYVIDPGTARISRYSYRTKVQRLPIEPISQASANQR 396 Query: 411 AGRCGRVAAGVCIRLYDEQDFLQRPKFTDPEILRSSLASVILRMKSLHLTDVESFPFIEP 470 GRCGRV+ G+CIRLY E DFL RP+FTDPEILR++LASVIL+M +L L D+ +FPF+E Sbjct: 397 KGRCGRVSEGICIRLYSEDDFLSRPEFTDPEILRTNLASVILQMTALGLGDIAAFPFVEA 456 Query: 471 PLGRAIADGYQLLQELGAV--EEQGGVNRLTPLGKQLARLPLDPRVGRMILAGRDNACLT 528 P R I DG +LL+ELGA+ +EQ +LTPLG+QL++LP+DPR+ RM+L + + C+ Sbjct: 457 PDKRNIQDGVRLLEELGAITADEQQTAYKLTPLGRQLSQLPVDPRLARMVLEAQKHGCVR 516 Query: 529 ELLIIAAAVSVQDPRDRPMDAQNAADNAHKKFADEKSEFASYLKIWKWFEDAIAHKKSNR 588 E +II +A+S+QDPR+RP+D Q A+D H++F D++S+F +++ +W + + SN Sbjct: 517 EAMIITSALSIQDPRERPVDKQQASDEKHRRFHDKESDFLAFVNLWNYLGEQQKALSSN- 575 Query: 589 QLQEHCRENFLSQLRLREWRDVHSQLLTIVKEQGWRLNEAAATYDQLHLALLTGLLGNVG 648 Q + CR ++L+ LR+REW+D+++QL +VKE G +N A Y ++H+ALLTGLL ++G Sbjct: 576 QFRRLCRTDYLNYLRVREWQDIYTQLRQVVKELGIPVNSEPAEYREIHVALLTGLLSHIG 635 Query: 649 FKSDDDAQYLGARGIKFNIWPGAHLTKKPGRWVMAAELVDTARLYARCVANIQPEWLEKL 708 K D +Y GAR +F+I+PG+ L KKP +W M AELV+T+RL+ R A I+PEW+E + Sbjct: 636 MKDADKQEYTGARNARFSIFPGSGLFKKPPKWTMVAELVETSRLWGRIAARIEPEWVEPV 695 Query: 709 GGHLLKKSWGEPRWEKRAAQVTASERATLYGLVVYSQRRINYGNINPVEAREIFIRDALV 768 HL+K+S+ EP WE+ V A+E+ T+YGL + + R++NY I+P RE+FIR ALV Sbjct: 696 AQHLIKRSYSEPHWERAQGAVMATEKVTVYGLPIVAARKVNYSQIDPALCRELFIRHALV 755 Query: 769 GGDFETRAPFFAHNQKLVREIENLEHKSRRLDVLVDDELIIGFYDKLIPQDICNGVDFEK 828 GD++TR FF N KL E+E LEHKSRR D+LVDD+ + FYD+ I D+ + F+ Sbjct: 756 EGDWQTRHAFFRENLKLRAEVEELEHKSRRRDILVDDDTLFEFYDQRISHDVISARHFDS 815 Query: 829 WHKQATAADPKLLYLNRDDLMRHEAAGVTTELFPKTMNVAGIAMALSYHFEPGAARDGVT 888 W K+ + P LL + L++ A ++ +P + + + LSY FEPGA DGVT Sbjct: 816 WWKKISRETPDLLNFEKSMLIKEGAEKISKLDYPNFWHQGNLKLRLSYQFEPGADADGVT 875 Query: 889 LTVPLYALNQVSADRCEWLVPGMLKEKVHLLLKSLPQKLRRHCVPLPDYAARFCERMEER 948 + +PL LNQV EW +PG+ +E V L+KSLP+ +RR+ VP P+YA F R+ Sbjct: 876 VHIPLPLLNQVDESGFEWQIPGLRRELVIALIKSLPKPVRRNFVPAPNYAEAFLGRV--- 932 Query: 949 KTFGRGNLIDAIIADIREQITLLVKPSDFKQETLSAHHAMNFKIVDEHGRQLEMGRNLAA 1008 T L+DA+ ++R + V D+ + + H + F++V++ ++L+ GR+LA Sbjct: 933 -TPLELPLLDALERELRRMTGVTVDREDWHWDQVPEHLKITFRVVNDKNKKLQEGRSLAE 991 Query: 1009 LQAEFGGQARQQFQKLAEQVAIAPREDEDSAAPLPAAAAGKGGATIATPAAPASVGEYSN 1068 L+ G+ ++ +A A G E S Sbjct: 992 LKNALKGKVQETL----------------------SAVADDG-------------IEQSG 1016 Query: 1069 LTSWSFGELPELLEITRGSGKQAQTLIGFPALVDRLTHCDLEVFDDPTEAARFHYAGLRR 1128 L WSFGELPE E RG+ K + +PALVD +++FD+P E + + GLRR Sbjct: 1017 LHIWSFGELPESYEQKRGNYK----VKAWPALVDERDSVAIKLFDNPLEQQQAMWCGLRR 1072 Query: 1129 LFALQMKEQLKYLEKNIPGLQQMGMQFMALGTQEELREQILNAGLERAFLQDPLPRNADE 1188 L L + +KYL + +P ++G+ F G EL + + G+++ + P ++ Sbjct: 1073 LLLLNIPSPIKYLHEKLPNKAKLGLYFNPYGKVLELIDDCIACGVDKLIDANGGPVWSEA 1132 Query: 1189 -FNRRRDEGKARLGLLVNEIARLCGLILAEYHSLPKKLQG--IKAHAQAAADMQAQLSQL 1245 F ++ +A L V +IA+ IL ++ K+L+G + A +D++AQ+S L Sbjct: 1133 GFTALHEKVRAELNDTVVDIAKQVERILTTVFNINKRLKGRVDMSMALGLSDIKAQMSGL 1192 Query: 1246 VGKRFVAETDYGNLSHYPRYLKAINVRLDKLRADPARDTRLLAEWNSVALPYQRGLKDR- 1304 V + FV + L RYL+AI RL+KL DP RD + + SV +Q+ + Sbjct: 1193 VYRGFVTGNGFKRLGDTLRYLQAIEKRLEKLAVDPHRDRAQMLKVESVQQAWQQWINKLP 1252 Query: 1305 -AGRADPKMTEFRWMLEELRVSLYAQELKTPMPVSVKRL 1342 A R D + E RWM+EELRVS +AQ+L TP P+S KR+ Sbjct: 1253 PARREDDDVKEIRWMIEELRVSYFAQQLGTPYPISDKRI 1291 >hrpA [L] COG1643 HrpA-like helicases Eco Escherichia coli K12 Length = 1281 Score = 1129 bits (2919), Expect = 0.0, Method: Compositional matrix adjust. Identities = 598/1306 (45%), Positives = 839/1306 (64%), Gaps = 83/1306 (6%) Query: 51 PPVTFPEELPVSGRRHEIAEALRRHQVIIVSGETGSGKTTQLPKICLELGRGAKGLIGHT 110 P +T+P+ LPVS ++ +I EA+R HQV+IV+GETGSGKTTQLPKIC+ELGRG KGLIGHT Sbjct: 50 PEITYPDNLPVSQKKQDILEAIRDHQVVIVAGETGSGKTTQLPKICMELGRGIKGLIGHT 109 Query: 111 QPRRIAASSTAKRIAQELNSPPGELVGYKVRFNDTLSKGAWIKLMTDGILLAETQTDPLL 170 QPRR+AA + A RIA+EL + PG +GYKVRF+D +S +KLMTDGILLAE Q D LL Sbjct: 110 QPRRLAARTVANRIAEELKTEPGGCIGYKVRFSDHVSDNTMVKLMTDGILLAEIQQDRLL 169 Query: 171 RQYDTIIIDEAHERSLNIDFLLGYLKQLLPKRPDLKIIITSATIDADRFARHFGRELKGE 230 QYDTIIIDEAHERSLNIDFLLGYLK+LLP+RPDLKIIITSATID +RF+RHF Sbjct: 170 MQYDTIIIDEAHERSLNIDFLLGYLKELLPRRPDLKIIITSATIDPERFSRHFNN----- 224 Query: 231 LVPAPVIEVSGRLYPVEIRYRPIDNADRSGVSTEVAQARARAEGRASQAQKDREQRDLMD 290 AP+IEVSGR YPVE+RYRPI V +A D +RD + Sbjct: 225 ---APIIEVSGRTYPVEVRYRPI-----------VEEA-------------DDTERDQLQ 257 Query: 291 AVVDAVDELARIGSGDVLVFLPGEREIRDAAEALRKHHPPHVEILPLFARLSAQEQERVF 350 A+ DAVDEL++ GD+L+F+ GEREIRD A+AL K + H EILPL+ARLS EQ RVF Sbjct: 258 AIFDAVDELSQESHGDILIFMSGEREIRDTADALNKLNLRHTEILPLYARLSNSEQNRVF 317 Query: 351 KTSNARRIVLATNVAETSLTVPGIRYVVDAGLARVKRYSYRNKVEQLQIEPVAQSAANQR 410 ++ + RRIVLATNVAETSLTVPGI+YV+D G AR+ RYSYR KV++L IEP++Q++ANQR Sbjct: 318 QSHSGRRIVLATNVAETSLTVPGIKYVIDPGTARISRYSYRTKVQRLPIEPISQASANQR 377 Query: 411 AGRCGRVAAGVCIRLYDEQDFLQRPKFTDPEILRSSLASVILRMKSLHLTDVESFPFIEP 470 GRCGRV+ G+CIRLY E DFL RP+FTDPEILR++LASVIL+M +L L D+ +FPF+E Sbjct: 378 KGRCGRVSEGICIRLYSEDDFLSRPEFTDPEILRTNLASVILQMTALGLGDIAAFPFVEA 437 Query: 471 PLGRAIADGYQLLQELGAV--EEQGGVNRLTPLGKQLARLPLDPRVGRMILAGRDNACLT 528 P R I DG +LL+ELGA+ +EQ +LTPLG+QL++LP+DPR+ RM+L + + C+ Sbjct: 438 PDKRNIQDGVRLLEELGAITTDEQASAYKLTPLGRQLSQLPVDPRLARMVLEAQKHGCVR 497 Query: 529 ELLIIAAAVSVQDPRDRPMDAQNAADNAHKKFADEKSEFASYLKIWKWFEDAIAHKKSNR 588 E +II +A+S+QDPR+RPMD Q A+D H++F D++S+F +++ +W + + SN Sbjct: 498 EAMIITSALSIQDPRERPMDKQQASDEKHRRFHDKESDFLAFVNLWNYLGEQQKALSSN- 556 Query: 589 QLQEHCRENFLSQLRLREWRDVHSQLLTIVKEQGWRLNEAAATYDQLHLALLTGLLGNVG 648 + CR ++L+ LR+REW+D+++QL +VKE G +N A Y ++H+ALLTGLL ++G Sbjct: 557 AFRRLCRTDYLNYLRVREWQDIYTQLRQVVKELGIPVNSEPAEYREIHIALLTGLLSHIG 616 Query: 649 FKSDDDAQYLGARGIKFNIWPGAHLTKKPGRWVMAAELVDTARLYARCVANIQPEWLEKL 708 K D +Y GAR +F+I+PG+ L KKP +WVM AELV+T+RL+ R A I PEW+E + Sbjct: 617 MKDADKQEYTGARNARFSIFPGSGLFKKPPKWVMVAELVETSRLWGRIAARIDPEWVEPV 676 Query: 709 GGHLLKKSWGEPRWEKRAAQVTASERATLYGLVVYSQRRINYGNINPVEAREIFIRDALV 768 HL+K+++ EP WE+ V A+E+ T+YGL + + R++NY I+P RE+FIR ALV Sbjct: 677 AQHLIKRTYSEPHWERAQGAVMATEKVTVYGLPIVAARKVNYSQIDPALCRELFIRHALV 736 Query: 769 GGDFETRAPFFAHNQKLVREIENLEHKSRRLDVLVDDELIIGFYDKLIPQDICNGVDFEK 828 GD++TR FF N KL E+E LEHKSRR D+LVDDE + FYD+ I D+ + F+ Sbjct: 737 EGDWQTRHAFFRENLKLRAEVEELEHKSRRRDILVDDETLFEFYDQRISHDVISARHFDS 796 Query: 829 WHKQATAADPKLLYLNRDDLMRHEAAGVTTELFPKTMNVAGIAMALSYHFEPGAARDGVT 888 W K+ + P LL + L++ A ++ +P + + + LSY FEPGA DGVT Sbjct: 797 WWKKVSRETPDLLNFEKSMLIKEGAEKISKLDYPNFWHQGNLKLRLSYQFEPGADADGVT 856 Query: 889 LTVPLYALNQVSADRCEWLVPGMLKEKVHLLLKSLPQKLRRHCVPLPDYAARFCERMEER 948 + +PL LNQV EW +PG+ +E V L+KSLP+ +RR+ VP P+YA F R++ Sbjct: 857 VHIPLPLLNQVEESGFEWQIPGLRRELVIALIKSLPKPVRRNFVPAPNYAEAFLGRVKPL 916 Query: 949 KTFGRGNLIDAIIADIREQITLLVKPSDFKQETLSAHHAMNFKIVDEHGRQLEMGRNLAA 1008 + L+D++ ++R + V D+ + + H + F++VD+ ++L+ GR+L Sbjct: 917 EL----PLLDSLERELRRMTGVTVDREDWHWDQVPDHLKITFRVVDDKNKKLKEGRSLQD 972 Query: 1009 LQAEFGGQARQQFQKLAEQVAIAPREDEDSAAPLPAAAAGKGGATIATPAAPASVGEYSN 1068 L+ G+ ++ +A A G E S Sbjct: 973 LKDALKGKVQETL----------------------SAVADDG-------------IEQSG 997 Query: 1069 LTSWSFGELPELLEITRGSGKQAQTLIGFPALVDRLTHCDLEVFDDPTEAARFHYAGLRR 1128 L WSFG+LPE E RG+ K + +PALVD +++FD+P E + + GLRR Sbjct: 998 LHIWSFGQLPESYEQKRGNYK----VKAWPALVDERDSVAIKLFDNPLEQKQAMWNGLRR 1053 Query: 1129 LFALQMKEQLKYLEKNIPGLQQMGMQFMALGTQEELREQILNAGLERAFLQDPLPRNADE 1188 L L + +KYL + +P ++G+ F G EL + ++ G+++ + P +E Sbjct: 1054 LLLLNIPSPIKYLHEKLPNKAKLGLYFNPYGKVLELIDDCISCGVDKLIDANGGPVWTEE 1113 Query: 1189 -FNRRRDEGKARLGLLVNEIARLCGLILAEYHSLPKKLQG--IKAHAQAAADMQAQLSQL 1245 F ++ +A L V +IA+ IL ++ K+L+G A +D++AQ+ L Sbjct: 1114 GFAALHEKVRAELNDTVVDIAKQVEQILTAVFNINKRLKGRVDMTMALGLSDIKAQMGGL 1173 Query: 1246 VGKRFVAETDYGNLSHYPRYLKAINVRLDKLRADPARDTRLLAEWNSVALPYQRGLKDR- 1304 V + FV + L RYL+AI RL+KL DP RD + + +V +Q+ + Sbjct: 1174 VYRGFVTGNGFKRLGDTLRYLQAIEKRLEKLAVDPHRDRAQMLKVENVQQAWQQWINKLP 1233 Query: 1305 -AGRADPKMTEFRWMLEELRVSLYAQELKTPMPVSVKRLQKVWESM 1349 A R D + E RWM+EELRVS +AQ+L TP P+S KR+ + E + Sbjct: 1234 PARREDEDVKEIRWMIEELRVSYFAQQLGTPYPISDKRILQAMEQI 1279 >ZhrpA [L] COG1643 HrpA-like helicases EcZ Escherichia coli O157:H7 EDL933 Length = 1281 Score = 1125 bits (2911), Expect = 0.0, Method: Compositional matrix adjust. Identities = 596/1306 (45%), Positives = 836/1306 (64%), Gaps = 83/1306 (6%) Query: 51 PPVTFPEELPVSGRRHEIAEALRRHQVIIVSGETGSGKTTQLPKICLELGRGAKGLIGHT 110 P +T+P+ LPVS ++ +I EA+R HQV+IV+GETGSGKTTQLPKIC+ELGRG KGLIGHT Sbjct: 50 PEITYPDNLPVSQKKQDILEAIRDHQVVIVAGETGSGKTTQLPKICMELGRGIKGLIGHT 109 Query: 111 QPRRIAASSTAKRIAQELNSPPGELVGYKVRFNDTLSKGAWIKLMTDGILLAETQTDPLL 170 QPRR+AA + A RIA+EL + PG +GYKVRF+D +S +KLMTDGILLAE Q D LL Sbjct: 110 QPRRLAARTVANRIAEELKTEPGGCIGYKVRFSDHVSDNTMVKLMTDGILLAEIQQDRLL 169 Query: 171 RQYDTIIIDEAHERSLNIDFLLGYLKQLLPKRPDLKIIITSATIDADRFARHFGRELKGE 230 QYDTIIIDEAHERSLNIDFLLGYLK+LLP+RPDLKIIITSATID +RF+RHF Sbjct: 170 MQYDTIIIDEAHERSLNIDFLLGYLKELLPRRPDLKIIITSATIDPERFSRHFNN----- 224 Query: 231 LVPAPVIEVSGRLYPVEIRYRPIDNADRSGVSTEVAQARARAEGRASQAQKDREQRDLMD 290 AP+IEVSGR YPVE+RYRPI V +A D +RD + Sbjct: 225 ---APIIEVSGRTYPVEVRYRPI-----------VEEA-------------DDTERDQLQ 257 Query: 291 AVVDAVDELARIGSGDVLVFLPGEREIRDAAEALRKHHPPHVEILPLFARLSAQEQERVF 350 A+ DAVDEL++ GD+L+F+ GEREIRD A+AL K + H EILPL+ARLS EQ RVF Sbjct: 258 AIFDAVDELSQESPGDILIFMSGEREIRDTADALNKLNLRHTEILPLYARLSNSEQNRVF 317 Query: 351 KTSNARRIVLATNVAETSLTVPGIRYVVDAGLARVKRYSYRNKVEQLQIEPVAQSAANQR 410 ++ + RRIVLATNVAETSLTVPGI+YV+D G AR+ RYSYR KV++L IEP++Q++ANQR Sbjct: 318 QSHSGRRIVLATNVAETSLTVPGIKYVIDPGTARISRYSYRTKVQRLPIEPISQASANQR 377 Query: 411 AGRCGRVAAGVCIRLYDEQDFLQRPKFTDPEILRSSLASVILRMKSLHLTDVESFPFIEP 470 GRCGRV+ G+CIRLY E DFL RP+FTDPEILR++LASVIL+M +L L D+ +FPF+E Sbjct: 378 KGRCGRVSEGICIRLYSEDDFLSRPEFTDPEILRTNLASVILQMTALGLGDIAAFPFVEA 437 Query: 471 PLGRAIADGYQLLQELGAV--EEQGGVNRLTPLGKQLARLPLDPRVGRMILAGRDNACLT 528 P R I DG +LL+ELGA+ +EQ +LTPLG+QL++LP+DPR+ RM+L + + C+ Sbjct: 438 PDKRNIQDGVRLLEELGAITTDEQASAYKLTPLGRQLSQLPVDPRLARMVLEAQKHGCVR 497 Query: 529 ELLIIAAAVSVQDPRDRPMDAQNAADNAHKKFADEKSEFASYLKIWKWFEDAIAHKKSNR 588 E +II +A+S+QDPR+RPMD Q A+D H++F D++S+F +++ +W + + SN Sbjct: 498 EAMIITSALSIQDPRERPMDKQQASDEKHRRFHDKESDFLAFVNLWNYLGEQQKALSSN- 556 Query: 589 QLQEHCRENFLSQLRLREWRDVHSQLLTIVKEQGWRLNEAAATYDQLHLALLTGLLGNVG 648 + CR ++L+ LR+REW+D+++QL +VKE G +N A Y ++H+ALLTGLL ++G Sbjct: 557 AFRRLCRTDYLNYLRVREWQDIYTQLRQVVKELGIPVNSEPAEYREIHIALLTGLLSHIG 616 Query: 649 FKSDDDAQYLGARGIKFNIWPGAHLTKKPGRWVMAAELVDTARLYARCVANIQPEWLEKL 708 K D +Y GAR +F+I+PG+ L KKP +WVM AELV+T+RL+ R A I PEW+E + Sbjct: 617 MKDADKQEYTGARNARFSIFPGSGLFKKPPKWVMVAELVETSRLWGRIAARIDPEWVEPV 676 Query: 709 GGHLLKKSWGEPRWEKRAAQVTASERATLYGLVVYSQRRINYGNINPVEAREIFIRDALV 768 HL+K+++ EP WE+ V A+E+ T+YGL + + R++NY I+P RE+FIR ALV Sbjct: 677 AQHLIKRTYSEPHWERAQGAVMATEKVTVYGLPIVAARKVNYSQIDPALCRELFIRHALV 736 Query: 769 GGDFETRAPFFAHNQKLVREIENLEHKSRRLDVLVDDELIIGFYDKLIPQDICNGVDFEK 828 GD++TR FF N KL E+E LEHKSRR D+LVDDE + FYD+ I D+ + F+ Sbjct: 737 EGDWQTRHAFFRENLKLRAEVEELEHKSRRRDILVDDETLFEFYDQRIGHDVISARHFDS 796 Query: 829 WHKQATAADPKLLYLNRDDLMRHEAAGVTTELFPKTMNVAGIAMALSYHFEPGAARDGVT 888 W K+ + P LL + L++ A ++ +P + + + LSY FEPGA DGVT Sbjct: 797 WWKKVSRETPDLLNFEKSMLIKEGAEKISKLDYPNFWHQGNLKLRLSYQFEPGADADGVT 856 Query: 889 LTVPLYALNQVSADRCEWLVPGMLKEKVHLLLKSLPQKLRRHCVPLPDYAARFCERMEER 948 + +PL LNQV EW +PG+ +E V L+KSLP+ +RR+ VP P+YA F R+ Sbjct: 857 VHIPLPLLNQVEESGFEWQIPGLRRELVIALIKSLPKPVRRNFVPAPNYAEAFLGRVTPL 916 Query: 949 KTFGRGNLIDAIIADIREQITLLVKPSDFKQETLSAHHAMNFKIVDEHGRQLEMGRNLAA 1008 + L+D++ ++R + V D+ + + H + F++VD+ ++L+ GR+L Sbjct: 917 EL----PLLDSLERELRRMTGVTVDREDWHWDQVPDHLKITFRVVDDKNKKLKEGRSLQD 972 Query: 1009 LQAEFGGQARQQFQKLAEQVAIAPREDEDSAAPLPAAAAGKGGATIATPAAPASVGEYSN 1068 L+ G+ ++ +A+ E S Sbjct: 973 LKDALKGKVQETLSAVADDGI-----------------------------------EQSG 997 Query: 1069 LTSWSFGELPELLEITRGSGKQAQTLIGFPALVDRLTHCDLEVFDDPTEAARFHYAGLRR 1128 L WSFG+LPE E RG+ K + +PALVD +++FD+P E + + GLRR Sbjct: 998 LHIWSFGQLPESYEQKRGNYK----VKAWPALVDERDSVAIKLFDNPLEQKQAMWNGLRR 1053 Query: 1129 LFALQMKEQLKYLEKNIPGLQQMGMQFMALGTQEELREQILNAGLERAFLQDPLPRNADE 1188 L L + +KYL + +P ++G+ F G EL + ++ G+++ + P +E Sbjct: 1054 LLLLNIPSPIKYLHEKLPNKAKLGLYFNPYGKVLELIDDCISCGVDQLIDANGGPVWTEE 1113 Query: 1189 -FNRRRDEGKARLGLLVNEIARLCGLILAEYHSLPKKLQG--IKAHAQAAADMQAQLSQL 1245 F ++ +A L V +IA+ IL ++ K+L+G A +D++AQ+ L Sbjct: 1114 GFAALHEKVRAELNDTVVDIAKQVEQILTAVFNINKRLKGRVDMTMALGLSDIKAQMGGL 1173 Query: 1246 VGKRFVAETDYGNLSHYPRYLKAINVRLDKLRADPARDTRLLAEWNSVALPYQRGLKDR- 1304 V + FV + L RYL+AI RL+KL DP RD + + +V +Q+ Sbjct: 1174 VYRGFVTGNGFKRLGDTLRYLQAIEKRLEKLAVDPHRDRAQMLKVENVQQAWQQWFNKLP 1233 Query: 1305 -AGRADPKMTEFRWMLEELRVSLYAQELKTPMPVSVKRLQKVWESM 1349 A R D + E RWM+EELRVS +AQ+L TP P+S KR+ + E + Sbjct: 1234 PARREDEDVKEIRWMIEELRVSYFAQQLGTPYPISDKRILQAMEQI 1279 >ECs2015 [L] COG1643 HrpA-like helicases Ecs Escherichia coli O157:H7 Length = 1281 Score = 1125 bits (2911), Expect = 0.0, Method: Compositional matrix adjust. Identities = 596/1306 (45%), Positives = 836/1306 (64%), Gaps = 83/1306 (6%) Query: 51 PPVTFPEELPVSGRRHEIAEALRRHQVIIVSGETGSGKTTQLPKICLELGRGAKGLIGHT 110 P +T+P+ LPVS ++ +I EA+R HQV+IV+GETGSGKTTQLPKIC+ELGRG KGLIGHT Sbjct: 50 PEITYPDNLPVSQKKQDILEAIRDHQVVIVAGETGSGKTTQLPKICMELGRGIKGLIGHT 109 Query: 111 QPRRIAASSTAKRIAQELNSPPGELVGYKVRFNDTLSKGAWIKLMTDGILLAETQTDPLL 170 QPRR+AA + A RIA+EL + PG +GYKVRF+D +S +KLMTDGILLAE Q D LL Sbjct: 110 QPRRLAARTVANRIAEELKTEPGGCIGYKVRFSDHVSDNTMVKLMTDGILLAEIQQDRLL 169 Query: 171 RQYDTIIIDEAHERSLNIDFLLGYLKQLLPKRPDLKIIITSATIDADRFARHFGRELKGE 230 QYDTIIIDEAHERSLNIDFLLGYLK+LLP+RPDLKIIITSATID +RF+RHF Sbjct: 170 MQYDTIIIDEAHERSLNIDFLLGYLKELLPRRPDLKIIITSATIDPERFSRHFNN----- 224 Query: 231 LVPAPVIEVSGRLYPVEIRYRPIDNADRSGVSTEVAQARARAEGRASQAQKDREQRDLMD 290 AP+IEVSGR YPVE+RYRPI V +A D +RD + Sbjct: 225 ---APIIEVSGRTYPVEVRYRPI-----------VEEA-------------DDTERDQLQ 257 Query: 291 AVVDAVDELARIGSGDVLVFLPGEREIRDAAEALRKHHPPHVEILPLFARLSAQEQERVF 350 A+ DAVDEL++ GD+L+F+ GEREIRD A+AL K + H EILPL+ARLS EQ RVF Sbjct: 258 AIFDAVDELSQESPGDILIFMSGEREIRDTADALNKLNLRHTEILPLYARLSNSEQNRVF 317 Query: 351 KTSNARRIVLATNVAETSLTVPGIRYVVDAGLARVKRYSYRNKVEQLQIEPVAQSAANQR 410 ++ + RRIVLATNVAETSLTVPGI+YV+D G AR+ RYSYR KV++L IEP++Q++ANQR Sbjct: 318 QSHSGRRIVLATNVAETSLTVPGIKYVIDPGTARISRYSYRTKVQRLPIEPISQASANQR 377 Query: 411 AGRCGRVAAGVCIRLYDEQDFLQRPKFTDPEILRSSLASVILRMKSLHLTDVESFPFIEP 470 GRCGRV+ G+CIRLY E DFL RP+FTDPEILR++LASVIL+M +L L D+ +FPF+E Sbjct: 378 KGRCGRVSEGICIRLYSEDDFLSRPEFTDPEILRTNLASVILQMTALGLGDIAAFPFVEA 437 Query: 471 PLGRAIADGYQLLQELGAV--EEQGGVNRLTPLGKQLARLPLDPRVGRMILAGRDNACLT 528 P R I DG +LL+ELGA+ +EQ +LTPLG+QL++LP+DPR+ RM+L + + C+ Sbjct: 438 PDKRNIQDGVRLLEELGAITTDEQASAYKLTPLGRQLSQLPVDPRLARMVLEAQKHGCVR 497 Query: 529 ELLIIAAAVSVQDPRDRPMDAQNAADNAHKKFADEKSEFASYLKIWKWFEDAIAHKKSNR 588 E +II +A+S+QDPR+RPMD Q A+D H++F D++S+F +++ +W + + SN Sbjct: 498 EAMIITSALSIQDPRERPMDKQQASDEKHRRFHDKESDFLAFVNLWNYLGEQQKALSSN- 556 Query: 589 QLQEHCRENFLSQLRLREWRDVHSQLLTIVKEQGWRLNEAAATYDQLHLALLTGLLGNVG 648 + CR ++L+ LR+REW+D+++QL +VKE G +N A Y ++H+ALLTGLL ++G Sbjct: 557 AFRRLCRTDYLNYLRVREWQDIYTQLRQVVKELGIPVNSEPAEYREIHIALLTGLLSHIG 616 Query: 649 FKSDDDAQYLGARGIKFNIWPGAHLTKKPGRWVMAAELVDTARLYARCVANIQPEWLEKL 708 K D +Y GAR +F+I+PG+ L KKP +WVM AELV+T+RL+ R A I PEW+E + Sbjct: 617 MKDADKQEYTGARNARFSIFPGSGLFKKPPKWVMVAELVETSRLWGRIAARIDPEWVEPV 676 Query: 709 GGHLLKKSWGEPRWEKRAAQVTASERATLYGLVVYSQRRINYGNINPVEAREIFIRDALV 768 HL+K+++ EP WE+ V A+E+ T+YGL + + R++NY I+P RE+FIR ALV Sbjct: 677 AQHLIKRTYSEPHWERAQGAVMATEKVTVYGLPIVAARKVNYSQIDPALCRELFIRHALV 736 Query: 769 GGDFETRAPFFAHNQKLVREIENLEHKSRRLDVLVDDELIIGFYDKLIPQDICNGVDFEK 828 GD++TR FF N KL E+E LEHKSRR D+LVDDE + FYD+ I D+ + F+ Sbjct: 737 EGDWQTRHAFFRENLKLRAEVEELEHKSRRRDILVDDETLFEFYDQRIGHDVISARHFDS 796 Query: 829 WHKQATAADPKLLYLNRDDLMRHEAAGVTTELFPKTMNVAGIAMALSYHFEPGAARDGVT 888 W K+ + P LL + L++ A ++ +P + + + LSY FEPGA DGVT Sbjct: 797 WWKKVSRETPDLLNFEKSMLIKEGAEKISKLDYPNFWHQGNLKLRLSYQFEPGADADGVT 856 Query: 889 LTVPLYALNQVSADRCEWLVPGMLKEKVHLLLKSLPQKLRRHCVPLPDYAARFCERMEER 948 + +PL LNQV EW +PG+ +E V L+KSLP+ +RR+ VP P+YA F R+ Sbjct: 857 VHIPLPLLNQVEESGFEWQIPGLRRELVIALIKSLPKPVRRNFVPAPNYAEAFLGRVTPL 916 Query: 949 KTFGRGNLIDAIIADIREQITLLVKPSDFKQETLSAHHAMNFKIVDEHGRQLEMGRNLAA 1008 + L+D++ ++R + V D+ + + H + F++VD+ ++L+ GR+L Sbjct: 917 EL----PLLDSLERELRRMTGVTVDREDWHWDQVPDHLKITFRVVDDKNKKLKEGRSLQD 972 Query: 1009 LQAEFGGQARQQFQKLAEQVAIAPREDEDSAAPLPAAAAGKGGATIATPAAPASVGEYSN 1068 L+ G+ ++ +A+ E S Sbjct: 973 LKDALKGKVQETLSAVADDGI-----------------------------------EQSG 997 Query: 1069 LTSWSFGELPELLEITRGSGKQAQTLIGFPALVDRLTHCDLEVFDDPTEAARFHYAGLRR 1128 L WSFG+LPE E RG+ K + +PALVD +++FD+P E + + GLRR Sbjct: 998 LHIWSFGQLPESYEQKRGNYK----VKAWPALVDERDSVAIKLFDNPLEQKQAMWNGLRR 1053 Query: 1129 LFALQMKEQLKYLEKNIPGLQQMGMQFMALGTQEELREQILNAGLERAFLQDPLPRNADE 1188 L L + +KYL + +P ++G+ F G EL + ++ G+++ + P +E Sbjct: 1054 LLLLNIPSPIKYLHEKLPNKAKLGLYFNPYGKVLELIDDCISCGVDQLIDANGGPVWTEE 1113 Query: 1189 -FNRRRDEGKARLGLLVNEIARLCGLILAEYHSLPKKLQG--IKAHAQAAADMQAQLSQL 1245 F ++ +A L V +IA+ IL ++ K+L+G A +D++AQ+ L Sbjct: 1114 GFAALHEKVRAELNDTVVDIAKQVEQILTAVFNINKRLKGRVDMTMALGLSDIKAQMGGL 1173 Query: 1246 VGKRFVAETDYGNLSHYPRYLKAINVRLDKLRADPARDTRLLAEWNSVALPYQRGLKDR- 1304 V + FV + L RYL+AI RL+KL DP RD + + +V +Q+ Sbjct: 1174 VYRGFVTGNGFKRLGDTLRYLQAIEKRLEKLAVDPHRDRAQMLKVENVQQAWQQWFNKLP 1233 Query: 1305 -AGRADPKMTEFRWMLEELRVSLYAQELKTPMPVSVKRLQKVWESM 1349 A R D + E RWM+EELRVS +AQ+L TP P+S KR+ + E + Sbjct: 1234 PARREDEDVKEIRWMIEELRVSYFAQQLGTPYPISDKRILQAMEQI 1279