BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.3403.p (405 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2389 [M] COG0845 Membrane-fusion protein Pae Pseudomonas aerug... 229 7e-60 SMc04350 [M] COG0845 Membrane-fusion protein Sme Sinorhizobium m... 224 4e-58 BMEI0359 [M] COG0845 Membrane-fusion protein Bme Brucella melite... 211 2e-54 YPO1364 [M] COG0845 Membrane-fusion protein Ype Yersinia pestis 183 7e-46 YPO2999 [M] COG0845 Membrane-fusion protein Ype Yersinia pestis 167 5e-41 >PA2389 [M] COG0845 Membrane-fusion protein Pae Pseudomonas aeruginosa Length = 391 Score = 229 bits (585), Expect = 7e-60, Method: Compositional matrix adjust. Identities = 145/360 (40%), Positives = 220/360 (61%), Gaps = 24/360 (6%) Query: 57 KLETVTVERADLEQVVNATGNVVAQDYVDVGSKVAGQISDVDVVIGETVKAGRLLATVAP 116 +TV+V R +E V+A G + + YVDVG++ +GQI + V G+ V G+LL + P Sbjct: 35 NFDTVSVSRGSIESSVSALGTLQPRRYVDVGAQASGQIRKLHVEAGDDVTEGQLLVEIDP 94 Query: 117 AVQSSRIESNRATLARLKAELAGQNAQLDFAQLQFQRQTQLKAENATREESYESSRMNMA 176 + Q +++++ R ++ LKA+LA Q AQ A+ Q+QRQ +L A ATR E +S++ M Sbjct: 95 STQQAKVDAGRYSIEMLKAQLAEQRAQYTLARQQYQRQQRLAAGGATRTEDVQSAQAQML 154 Query: 177 AAASRVDATNAQIQQTEAAIREDEAVQKQTRIEAPANGTIVTLNARPGQMVGANQE--VL 234 A +R++ AQI+Q +A++R DEA TRI AP +GT+V ++AR GQ + A Q+ ++ Sbjct: 155 ATQARIEMYQAQIRQAQASLRSDEAELGYTRIYAPMSGTVVAVDAREGQTLNAQQQTPLI 214 Query: 235 MRIADLSRMTVQVPVAEEDVTRLQKGMTAYFTTPGYPGKRWSGKLRQIMLL---PTDDSG 291 +RIA LS MTV V+E D+ R++ GM AYFTT G+RW+GK+RQI+ + P D S Sbjct: 215 LRIAKLSPMTVWAQVSEADIGRVKPGMPAYFTTLSGEGRRWTGKVRQILPVPPKPLDQSN 274 Query: 292 R--------------QGKKAYYTVLFDVANPSRELMSGMSADVYFVLARAEHVPTIPRTL 337 + G+ YTVL DV N +LM+ M+A V+FV A AE++ T P Sbjct: 275 QGGGSPTSGSGGQSGSGRVVLYTVLVDVDNGDHQLMAEMTAQVFFVAATAENILTAPVAA 334 Query: 338 VTKPGMDGTQTVKVVLADGTLESRKIKIGIRDGERAQVLSGLKEGEQVLLPANPPQPEGA 397 + G G Q VV ++G +SR+I+ GI D R QVL+GL+EG+++L+ A P+G+ Sbjct: 335 IHDDG-KGGQVAWVVGSNGKPQSRQIRTGISDRLRVQVLAGLEEGDRLLMAA----PDGS 389 >SMc04350 [M] COG0845 Membrane-fusion protein Sme Sinorhizobium meliloti Length = 421 Score = 224 bits (570), Expect = 4e-58, Method: Compositional matrix adjust. Identities = 151/374 (40%), Positives = 219/374 (58%), Gaps = 19/374 (5%) Query: 24 WGSALALVLVLGGGYWLYSRQQPVPPAAKPIPVKLETVTVERADLEQVVNATGNVVAQDY 83 W AL ++ V+G GY+ +SRQ PPA I T V R D+E+ V A G + A Sbjct: 36 WIFALLVLAVVGTGYYAWSRQG-APPATTVI-----TQAVTRGDIEESVTAVGTLDAVKS 89 Query: 84 VDVGSKVAGQISDVDVVIGETVKAGRLLATVAPAVQSSRIESNRATLARLKAELAGQNAQ 143 VD G++V+GQ+ + V IG+ V+ +L+A + PA +RIE + A LA L+A+L + AQ Sbjct: 90 VDAGAQVSGQLKSLHVGIGDKVEQNQLIAEIDPASIENRIEIDEAELANLEAQLVSKKAQ 149 Query: 144 LDFAQLQFQRQTQLKAENATREESYESSRMNMAAAASRVDATNAQIQQTEAAIREDEAVQ 203 L Q +RQ L A N+ + + + + + AAA + V A AQI++ +A + D Sbjct: 150 LVLKQSNIERQRNLVATNSVSQSTLDQAVADHAAAGADVQAIEAQIRKQKATLAGDRVDL 209 Query: 204 KQTRIEAPANGTIVTLNARPGQMVGANQE--VLMRIADLSRMTVQVPVAEEDVTRLQKGM 261 T+I AP GTIV A+ GQ + ANQ ++ IADLS MTV+ V+E DV +L+ GM Sbjct: 210 GYTKIYAPMAGTIVDDPAKEGQTLNANQTTPTIVTIADLSTMTVKAQVSEADVGKLKLGM 269 Query: 262 TAYFTTPGYPGKRWSGKLRQIMLLPTDDSGRQGKKAYYTVLFDVANPSRELMSGMSADVY 321 AYFT G PGKR++GKLRQI +P ++ Y LFDV NP+ ELM MSA V+ Sbjct: 270 DAYFTLLGQPGKRFTGKLRQIEPMPDTEN----NVVLYYALFDVPNPTGELMMSMSAQVF 325 Query: 322 FVLARAEHVPTIP----RTLVTKPGMDG--TQTVKVVLADGTLESRKIKIGIRDGERAQV 375 FV A A++V +P RT V DG V VV G ++R +++G+R+ A++ Sbjct: 326 FVQAAAKNVLVVPSAALRT-VEAAASDGPARAEVTVVAPSGATQTRTVEVGVRNRVSAEI 384 Query: 376 LSGLKEGEQVLLPA 389 +SGL+EGE+V++ A Sbjct: 385 VSGLQEGEKVVVDA 398 >BMEI0359 [M] COG0845 Membrane-fusion protein Bme Brucella melitensis Length = 408 Score = 211 bits (538), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 136/372 (36%), Positives = 208/372 (55%), Gaps = 15/372 (4%) Query: 20 RQKMWGSALALVLVLGGGYWLYSRQQPVPPAAKPIPVKLETVTVERADLEQVVNATGNVV 79 R +W SA A+++ G G++ Y + + + ETVT R D+E + A G + Sbjct: 26 RWWLWLSAAAIII--GAGWYFYGSYKADGEKSSYLA---ETVT--RGDIENAITAVGTLS 78 Query: 80 AQDYVDVGSKVAGQISDVDVVIGETVKAGRLLATVAPAVQSSRIESNRATLARLKAELAG 139 A V+VG++V+GQ+ V V +G+ VK G+L+A + P+ ++E A L LKA+L Sbjct: 79 ALRSVNVGAQVSGQLKSVKVEVGDHVKQGQLIAEIDPSPFEKKVEIAGAQLDNLKAQLLS 138 Query: 140 QNAQLDFAQLQFQRQTQLKAENATREESYESSRMNMAAAASRVDATNAQIQQTEAAIRED 199 ++AQL +L RQ L A + + + + ++ A + V A NAQI+Q EA + D Sbjct: 139 KDAQLTLKKLNAARQKSLLATRGVSQATVDQANADLLMAEAEVKALNAQIRQQEAQLASD 198 Query: 200 EAVQKQTRIEAPANGTIVTLNARPGQMVGANQE--VLMRIADLSRMTVQVPVAEEDVTRL 257 + T I +P GT+V A+ G+ + A Q ++ +ADL MTV+ V+E D+++L Sbjct: 199 KVDLGYTSIYSPMEGTVVDEAAKEGETLNAVQSAPTIVTVADLKVMTVEAQVSEADISKL 258 Query: 258 QKGMTAYFTTPGYPGKRWSGKLRQIMLLPTDDSGRQGKKAYYTVLFDVANPSRELMSGMS 317 + GM YFT G P KR++G LRQI P D+ Y LFDV NP+ ELM MS Sbjct: 259 KPGMPVYFTLLGQPDKRFTGTLRQIKPTPATDN----NVVLYYALFDVPNPTGELMIDMS 314 Query: 318 ADVYFVLARAEHVPTIPRTLVTKPGMDGTQTVKVVLAD--GTLESRKIKIGIRDGERAQV 375 A VYFVL A+ V +P +T G V V +AD GTL R +K+G+R+ A++ Sbjct: 315 AQVYFVLGEAKDVLVVPTAALTDKQKGGKPQVTVKVADESGTLVERPVKVGVRNRVLAEI 374 Query: 376 LSGLKEGEQVLL 387 SGL+EG++V++ Sbjct: 375 QSGLEEGDRVVV 386 >YPO1364 [M] COG0845 Membrane-fusion protein Ype Yersinia pestis Length = 371 Score = 183 bits (464), Expect = 7e-46, Method: Compositional matrix adjust. Identities = 130/370 (35%), Positives = 199/370 (53%), Gaps = 17/370 (4%) Query: 21 QKMWGSALALVLVLGGGYWLYSRQQPVPPAAKPIPVKLETVTVERADLEQVVNATGNVVA 80 Q+ W +A+A++L+ GG+++ P+PV +TV V DL+Q V ATG + A Sbjct: 8 QRRWLAAIAVLLI--GGFFIARH------LMAPVPVNYQTVKVVHRDLQQNVLATGKLDA 59 Query: 81 QDYVDVGSKVAGQISDVDVVIGETVKAGRLLATVAPAVQSSRIESNRATLARLKAELAGQ 140 VDVG++V+GQ+ + V IG+ VK G+LLA + P ++I+ ATL L A+ Sbjct: 60 VRKVDVGAQVSGQLEKLYVEIGDHVKRGQLLAMIDPQQAQNQIKEVEATLQDLNAQRIQA 119 Query: 141 NAQLDFAQLQFQRQTQLKAENATREESYESSRMNMAAAASRVDATNAQIQQTEAAIREDE 200 A+L A + RQ L + + + ++A ++V +AQI + +A++ + Sbjct: 120 KAELHLATVTLGRQQNLAKLQVVSRQDLDQAVTDLAVKNAKVGTIDAQINKAKASLDTAK 179 Query: 201 AVQKQTRIEAPANGTIVTLNARPGQMVGANQEV--LMRIADLSRMTVQVPVAEEDVTRLQ 258 T+I AP +G +V + GQ V A Q+ ++ +AD+S M VQ V+E DV L+ Sbjct: 180 INLDYTQISAPMDGDVVQITTLQGQTVIAAQQAPNILTLADMSTMLVQAQVSEADVINLK 239 Query: 259 KGMTAYFTTPGYPGKRWSGKLRQIMLLPTDDSGRQGKKAYYTVLFDVANPSRELMSGMSA 318 GM A FT G PGKR+SG L+ I LPT + + +Y+ F+V NP R L M+A Sbjct: 240 PGMKASFTVLGDPGKRFSGVLKDI--LPTPE--KVNDAIFYSARFEVPNPDRLLRLQMTA 295 Query: 319 DVYFVLARAEHVPTIPR-TLVTKPGMDGTQTVKVVLADGTLESRKIKIGIRDGERAQVLS 377 V LA + IP L + G + Q VL +G E R++ IGIR+ AQV+S Sbjct: 296 QVSIQLANVDQAVVIPLAALGDELGSNRYQV--TVLKEGKEEKREVTIGIRNNVDAQVIS 353 Query: 378 GLKEGEQVLL 387 GL GE V++ Sbjct: 354 GLSVGEDVIV 363 >YPO2999 [M] COG0845 Membrane-fusion protein Ype Yersinia pestis Length = 401 Score = 167 bits (422), Expect = 5e-41, Method: Compositional matrix adjust. Identities = 116/358 (32%), Positives = 181/358 (50%), Gaps = 24/358 (6%) Query: 47 VPPAAKPIPVKLETVTVERADLEQVVNATGNVVAQDYVDVGSKVAGQISDVDVVIGETVK 106 + P KP + T E DLEQ V A G + AQ V VG++V+GQI + V +G+ V+ Sbjct: 30 ISPPDKPSYI---TAVAEIRDLEQTVLADGTIKAQKQVTVGAQVSGQIKALHVTLGQQVE 86 Query: 107 AGRLLATVAPAVQSSRIESNRATLARLKAELAGQNAQLDFAQLQFQRQTQLKAENATREE 166 +L+A + Q + ++ L ++A+ A + A QL +QRQ Q+ A+ Sbjct: 87 KNQLVAEIDDLAQQNALKDAEEALKNVQAQRAAKIATQKNNQLTYQRQQQILAKGVGVRA 146 Query: 167 SYESSRMNMAAAASRVDATNAQIQQTEAAIREDEAVQKQTRIEAPANGTIVTLNARPGQM 226 ++S + + A + + A +AQI Q E A+ + T+I +P GT+V + GQ Sbjct: 147 DFDSIKATLEATQAEISALDAQIAQAEIAVSTAKLNLGYTKISSPIAGTVVAIPVEEGQT 206 Query: 227 VGANQE--VLMRIADLSRMTVQVPVAEEDVTRLQKGMTAYFTTPGYPGKRWSGKLRQIML 284 V A Q ++++A L MTV+ ++E DV +++ GM YFT G P KR+S LR I Sbjct: 207 VNAVQSAPTIIKVAQLDTMTVEAQISEADVVKVKTGMPVYFTILGEPEKRFSATLRAIE- 265 Query: 285 LPTDDS---------------GRQGKKAYYTVLFDVANPSRELMSGMSADVYFVLARAEH 329 P DS YY LFDVANP+ L M+A VY +L +A++ Sbjct: 266 -PAPDSINDETTTTSSSTSSSSSSSTAIYYNGLFDVANPTGALRISMTAQVYILLNQAKN 324 Query: 330 VPTIPRTLVTKPGMDGTQTVKVVLADGTLESRKIKIGIRDGERAQVLSGLKEGEQVLL 387 IP T + G V+VV G + R + +G+ + AQ+L+GL+ GE V++ Sbjct: 325 AVVIPATALEND--QGQYRVQVVDNSGKVSQRTVTVGLNNNVDAQILTGLQAGEHVIV 380