BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.3369.p (264 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1514 [QR] COG0500 SAM-dependent methyltransferases Rso Ralsto... 225 9e-59 PA1814 [QR] COG0500 SAM-dependent methyltransferases Pae Pseudom... 103 3e-22 NMA1506 [QR] COG0500 SAM-dependent methyltransferases NmA Neisse... 103 5e-22 NMB1296 [QR] COG0500 SAM-dependent methyltransferases Nme Neisse... 102 7e-22 STM0262 [QR] COG0500 SAM-dependent methyltransferases Sty Salmon... 94 3e-19 >RSc1514 [QR] COG0500 SAM-dependent methyltransferases Rso Ralstonia solanacearum Length = 257 Score = 225 bits (573), Expect = 9e-59, Method: Compositional matrix adjust. Identities = 121/236 (51%), Positives = 153/236 (64%), Gaps = 23/236 (9%) Query: 46 IFGFNAVQIGSPQIHALQANRMPY--RWL--TDNRMPVD----------GQSELE--IPQ 89 +FGF+A+Q+G P AL+ NR+P R + D P+D G+++ E +PQ Sbjct: 1 MFGFHALQLGHPGFGALRENRIPLIARVIDDIDPGAPIDTLDPADPDPPGEADAEPVVPQ 60 Query: 90 V-----VTHNFGELPFATQSLDLVVLPHVLEFAAEPHQVLREVERVLIPEGQVIICGFNP 144 V + ELPFA+QS+DLV LPHVLEF +PH+VLREV RVL+PEG+++I GFNP Sbjct: 61 RQATPRVICRYDELPFASQSIDLVALPHVLEFTDDPHEVLREVARVLMPEGRLVITGFNP 120 Query: 145 SSLWGMRQAAGRLTGAHFLPRDGEFIRLPRLKDWLKLLNMEVNRGHFGCYAPPCETTQWL 204 SLWGMRQ RL FLP + I RLKDWLKLL ++ RG FGCY PP T +WL Sbjct: 121 LSLWGMRQGMRRLGTESFLPAQSQMIAFTRLKDWLKLLGFDIVRGRFGCYCPPNRTDKWL 180 Query: 205 DRFGFMEKAGDRWWPYFGAVYIVQAIKRVPGMRLIGPALQRQKLQA--PRGVPVTN 258 R FMEKAGDRWWP FGAVY++QA+KRV +RL+GPA + +K P G PV Sbjct: 181 QRTAFMEKAGDRWWPIFGAVYMLQAVKRVRSVRLVGPAWKTRKSPTLVPAGTPVAT 236 >PA1814 [QR] COG0500 SAM-dependent methyltransferases Pae Pseudomonas aeruginosa Length = 253 Score = 103 bits (258), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 85/272 (31%), Positives = 121/272 (44%), Gaps = 45/272 (16%) Query: 5 AETAANVNNAEIIDLAAWLQTPIGNYLRQWEQRHLNTLTADIFGFNAVQIGSPQIHALQA 64 AE A++N A W Q P+G+ + E+R L FG V G HA Sbjct: 12 AEWLASINRAR-----DWFQGPLGSLMLAEERRLLCDELTRYFGGYLVHYGP---HA--- 60 Query: 65 NRMPYRWLTDNRMPVDGQSELEI------PQV-VTHNFGELPFATQSLDLVVLPHVLEFA 117 +P P GQ + + P V + G P + + D+V+L H L+F Sbjct: 61 -ELP---------PSTGQIQRGVRLGPPLPGVDIACEEGAWPLSEHAADVVLLQHGLDFC 110 Query: 118 AEPHQVLREVERVLIPEGQVIICGFNPSSLWGMRQ--AAGRLTGAHFLPRDGEFIRLPRL 175 PH++LRE R + P G +++ G NP SLWG+R A L A +P R Sbjct: 111 LSPHRLLREAARTVRPGGHLLLIGINPWSLWGIRHYFAGDALRQARCIPPS-------RA 163 Query: 176 KDWLKLLNMEVNRGHFGCYAPPCETTQWLDRFGFMEKAGDRWWPYFGAVYIVQAIKRVPG 235 DWL LL + + FGCY PP + W R +E+ GD W Y++ A K V G Sbjct: 164 CDWLNLLGFALEKRRFGCYRPPLASAAWQSRLARLERWGDAWQSSGAGFYLLVARKLVVG 223 Query: 236 MRLIGPALQRQKLQAPRG--VPV-TNRIHRTD 264 +R + RQ + PRG VP+ ++ R D Sbjct: 224 LRPL-----RQSKREPRGQLVPMPVAKVSRRD 250 >NMA1506 [QR] COG0500 SAM-dependent methyltransferases NmA Neisseria meningitidis Z2491 Length = 221 Score = 103 bits (256), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 70/223 (31%), Positives = 109/223 (48%), Gaps = 31/223 (13%) Query: 19 LAAWLQ-TPIGNYLRQWEQ----RHLNTLTADIFGFNAVQIGSPQIHALQANRMPYRWLT 73 + +W + T +G Y+ + EQ R+L++ G AVQ+G P WL+ Sbjct: 1 MDSWFEDTAMGRYVAKLEQDFFGRYLDSYRFS--GMCAVQVGGP-------------WLS 45 Query: 74 DNRMPVDGQSELEIPQVVTHNFGELPFATQSLDLVVLPHVLEFAAEPHQVLREVERVLIP 133 + + + +P+ ++ + + A S D+++ PH LE P Q+L E R+L P Sbjct: 46 LS------EDVVCVPRDMSMSAENMALADVSADMLLFPHTLE-GGVPSQILSEAHRILKP 98 Query: 134 EGQVIICGFNPSSLWGMRQAAGRLTGAHFLPRDGEFIRLPRLKDWLKLLNMEVNRGHFGC 193 G++++ GFNP SLWG R LP + LP LK L + ++ G F Sbjct: 99 SGRLMLTGFNPYSLWGF----SRWFDGERLPEKRFCLPLPELKRQLADVGFDIEFGKFMV 154 Query: 194 YAPPCETTQWLDRFGFMEKAGDRWWPYFGAVYIVQAIKRVPGM 236 Y PP + + + FMEKAGDRWWP AVY + +KR G+ Sbjct: 155 YLPPVSSLGQIRFWRFMEKAGDRWWPQCAAVYGLVLVKRAAGV 197 >NMB1296 [QR] COG0500 SAM-dependent methyltransferases Nme Neisseria meningitidis MC58 Length = 221 Score = 102 bits (255), Expect = 7e-22, Method: Compositional matrix adjust. Identities = 71/223 (31%), Positives = 109/223 (48%), Gaps = 31/223 (13%) Query: 19 LAAWLQ-TPIGNYLRQWEQ----RHLNTLTADIFGFNAVQIGSPQIHALQANRMPYRWLT 73 + AW + T +G Y+ + EQ R+L++ G AVQ+G P WL+ Sbjct: 1 MDAWFEDTAMGRYVAKLEQDFFGRYLDSYRFS--GMCAVQVGGP-------------WLS 45 Query: 74 DNRMPVDGQSELEIPQVVTHNFGELPFATQSLDLVVLPHVLEFAAEPHQVLREVERVLIP 133 + + + +P+ ++ + + A S D+++ PH LE P Q+L E R+L P Sbjct: 46 LS------EDVVCVPRDMSMSAENMALADVSADMLLFPHTLE-GGVPSQILSEAHRILKP 98 Query: 134 EGQVIICGFNPSSLWGMRQAAGRLTGAHFLPRDGEFIRLPRLKDWLKLLNMEVNRGHFGC 193 G++++ GFNP SLWG R LP + LP LK L + ++ G F Sbjct: 99 CGRLMLTGFNPYSLWGF----SRWFDGERLPEKRFCLPLPELKRRLADVGFDIEFGKFMV 154 Query: 194 YAPPCETTQWLDRFGFMEKAGDRWWPYFGAVYIVQAIKRVPGM 236 Y PP + + + FMEKAGDRWWP AVY + +KR G+ Sbjct: 155 YLPPVSSLGQIRFWRFMEKAGDRWWPQCAAVYGLVLVKRAAGV 197 >STM0262 [QR] COG0500 SAM-dependent methyltransferases Sty Salmonella typhimurium LT2 Length = 240 Score = 94.0 bits (232), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 59/171 (34%), Positives = 90/171 (52%), Gaps = 10/171 (5%) Query: 16 IIDLAAWLQTPIGNYLRQWEQRHLNTLTADIFGFNAVQIGSPQIHALQANRMPYRWLTDN 75 ++ W + P GNY R+ ++ LN A ++GF+ ++IG+ L A + Sbjct: 10 VVAPGCWGELPWGNYYREALEQQLNPWFAKMYGFHLLKIGN-----LSAEINSEACAVSH 64 Query: 76 RMPVDGQSELEIPQVVTHNFGELPFATQSLDLVVLPHVLEFAAEPHQVLREVERVLIPEG 135 ++ V Q P V + LPFA +S+D+ +L H L + +PH++LRE +RVLI +G Sbjct: 65 QVNVSSQGS---PMQVLADPLHLPFADKSVDVCLLAHTLPWCTDPHRLLREADRVLIDDG 121 Query: 136 QVIICGFNPSSLWGMRQAAGRLTGAHFLPRDGEFIRLPRLKDWLKLLNMEV 186 ++I GFNP SL G+R+ L P + L R DWL LLN EV Sbjct: 122 WLVISGFNPLSLMGLRKLVPVLRKTP--PYNSRMFTLMRQLDWLSLLNFEV 170