BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.3325.p (467 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0075 [GEPR] COG0477 Permeases of the major facilitator superf... 632 0.0 PA0229 [GEPR] COG0477 Permeases of the major facilitator superfa... 603 e-172 STM2654 [GEPR] COG0477 Permeases of the major facilitator superf... 583 e-166 kgtP [GEPR] COG0477 Permeases of the major facilitator superfami... 565 e-161 ECs3454 [GEPR] COG0477 Permeases of the major facilitator superf... 564 e-160 >RSp0075 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 437 Score = 632 bits (1629), Expect = 0.0, Method: Compositional matrix adjust. Identities = 304/435 (69%), Positives = 362/435 (83%) Query: 12 TTPSATTASTPLSAAEYRKRIFAILGASSGNLVEWFDFYVYSFCAIYFAPAFFPKGDATS 71 +TP+A + ++ + R+RIFAI+GASSGNLVEWFDFYVY+FC++YFAPAFFP G+ T+ Sbjct: 2 STPAAQASQAVMAPHDTRRRIFAIVGASSGNLVEWFDFYVYAFCSLYFAPAFFPSGNTTT 61 Query: 72 QLLNTAGVFAAGFLMRPIGGWLFGRIADKHGRKTSMLISVLMMCGGSLAVAIMPTYATIG 131 QL+NTAGVFAAGFLMRPIGGWLFGRIAD+HGR+ +M+ISVLMMCGGSL +A++P YA IG Sbjct: 62 QLMNTAGVFAAGFLMRPIGGWLFGRIADRHGRRNAMMISVLMMCGGSLVIAVLPIYAQIG 121 Query: 132 AWAPALLLLARLFQGLSVGGEYGTSATYMSEVAPNGRRGFFASFQYVTLIGGQLLAVLVL 191 A AP LLL+ARLFQGLSVGGEYGTSATYMSEVA GRRGFFASFQYVTLIGGQL A+LVL Sbjct: 122 ALAPFLLLVARLFQGLSVGGEYGTSATYMSEVALKGRRGFFASFQYVTLIGGQLCALLVL 181 Query: 192 FAMQQWLSKAELMAWGWRIPFVLGAVGALVAMYLRSSLAETSSAGARKKKDAGTIKGLLQ 251 +QQ LS AEL AWGWRIPFV+GA+ ALV++YLR SL ET S +R+ K AGTI+G Q Sbjct: 182 VILQQVLSTAELKAWGWRIPFVVGALSALVSLYLRRSLDETQSTASREAKHAGTIRGAWQ 241 Query: 252 HKRAFLNVVGFTAGGSLMFYTFTTYMQKYLVNTAGMDPKMANGVMTGALFVYMILQPIFG 311 HK AFL V+GFTAGGSL+FYTFTTYMQKYLVNTAGM+ K A+ VMT ALFVYM LQP+FG Sbjct: 242 HKGAFLRVIGFTAGGSLIFYTFTTYMQKYLVNTAGMNTKTASNVMTAALFVYMALQPVFG 301 Query: 312 AISDKIGRRNSMLCFSFLGMVCTFPILHFLKDVSSPGVAMALAILALTIVSFYTSISGLI 371 A+SD+IGRR SM+ F ++ T P++ L V++P A L AL I+SFYTSISGLI Sbjct: 302 ALSDRIGRRMSMILFGVGAVLFTVPLMRALGSVTNPYAAFGLVTAALAIISFYTSISGLI 361 Query: 372 KAEMFPPEVRALGVGLSYAVGNAIFGGSAEFVALSLKSVGVESAFYWYVSALCLVALIIS 431 KAEMFPPEVRA+GVGLSYA+ NA+FGGSAE+VAL KS G ES FYWYV+ LC V+LI+S Sbjct: 362 KAEMFPPEVRAMGVGLSYAIANAVFGGSAEYVALWFKSAGRESTFYWYVTTLCAVSLIVS 421 Query: 432 LRMPDPQRDGHLKGD 446 MPDP ++G+L+ + Sbjct: 422 YTMPDPSKEGYLRHE 436 >PA0229 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 432 Score = 603 bits (1556), Expect = e-172, Method: Compositional matrix adjust. Identities = 310/423 (73%), Positives = 360/423 (85%) Query: 24 SAAEYRKRIFAILGASSGNLVEWFDFYVYSFCAIYFAPAFFPKGDATSQLLNTAGVFAAG 83 S E RKRIFAI+GASSGNLVEWFDFYVY+FCAIYFAPAFFP + T QLLNTAGVFAAG Sbjct: 9 SNEERRKRIFAIVGASSGNLVEWFDFYVYAFCAIYFAPAFFPSDNPTVQLLNTAGVFAAG 68 Query: 84 FLMRPIGGWLFGRIADKHGRKTSMLISVLMMCGGSLAVAIMPTYATIGAWAPALLLLARL 143 FLMRPIGGW+FGRIADKHGRKT+MLISV+MMC GSLA+A MPTYA+IG APALLLLAR+ Sbjct: 69 FLMRPIGGWMFGRIADKHGRKTAMLISVVMMCAGSLAIACMPTYASIGTLAPALLLLARM 128 Query: 144 FQGLSVGGEYGTSATYMSEVAPNGRRGFFASFQYVTLIGGQLLAVLVLFAMQQWLSKAEL 203 FQGLSVGGEYGTSATYMSEVA G+RGFFASFQYVTLIGGQLLAVLV+ +QQ LS+ EL Sbjct: 129 FQGLSVGGEYGTSATYMSEVALKGQRGFFASFQYVTLIGGQLLAVLVVVILQQLLSEDEL 188 Query: 204 MAWGWRIPFVLGAVGALVAMYLRSSLAETSSAGARKKKDAGTIKGLLQHKRAFLNVVGFT 263 AWGWRIPFV+GA+ A++A++LR SL ET+S ++K++GT L +HKRAF V+GFT Sbjct: 189 RAWGWRIPFVIGAITAVIALWLRRSLNETASKSTLERKESGTFAELFKHKRAFFTVLGFT 248 Query: 264 AGGSLMFYTFTTYMQKYLVNTAGMDPKMANGVMTGALFVYMILQPIFGAISDKIGRRNSM 323 AGGSL+FYTFTTYMQKYLVNTAGM K A+ VMT AL YM++QP+FG +SD+IGR+ SM Sbjct: 249 AGGSLIFYTFTTYMQKYLVNTAGMSAKTASAVMTFALLAYMLMQPLFGMLSDRIGRKTSM 308 Query: 324 LCFSFLGMVCTFPILHFLKDVSSPGVAMALAILALTIVSFYTSISGLIKAEMFPPEVRAL 383 L F LG +CT PIL LK VSSP +A L ILAL IVS YTSISGLIKAEMFPPEVRAL Sbjct: 309 LWFGTLGTLCTLPILLALKTVSSPYMAFFLIILALAIVSLYTSISGLIKAEMFPPEVRAL 368 Query: 384 GVGLSYAVGNAIFGGSAEFVALSLKSVGVESAFYWYVSALCLVALIISLRMPDPQRDGHL 443 GVG+SYAVGNAIFGGSAE+VAL LKSVG+E+ FYWYVSA+CL+AL++ + +PD ++ +L Sbjct: 369 GVGVSYAVGNAIFGGSAEYVALGLKSVGMENVFYWYVSAMCLLALLVCVSLPDLRKVSYL 428 Query: 444 KGD 446 + Sbjct: 429 NDE 431 >STM2654 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 433 Score = 583 bits (1502), Expect = e-166, Method: Compositional matrix adjust. Identities = 296/423 (69%), Positives = 349/423 (82%), Gaps = 7/423 (1%) Query: 24 SAAEYRKRIFAILGASSGNLVEWFDFYVYSFCAIYFAPAFFPKGDATSQLLNTAGVFAAG 83 A E R+RI+AI+GASSGNLVEWFDFYVYSFC++YFA FFP G+ T+QLL TAGVFAAG Sbjct: 14 EAPEMRRRIWAIVGASSGNLVEWFDFYVYSFCSLYFAHIFFPSGNTTTQLLQTAGVFAAG 73 Query: 84 FLMRPIGGWLFGRIADKHGRKTSMLISVLMMCGGSLAVAIMPTYATIGAWAPALLLLARL 143 FLMRPIGGWLFGRIAD+ GRK SMLISV MMC GSL +A +P Y TIG WAPALLL+ARL Sbjct: 74 FLMRPIGGWLFGRIADRRGRKASMLISVCMMCMGSLVIACLPGYDTIGTWAPALLLIARL 133 Query: 144 FQGLSVGGEYGTSATYMSEVAPNGRRGFFASFQYVTLIGGQLLAVLVLFAMQQWLSKAEL 203 FQGLSVGGEYGTSATYMSEVA GR+GFFASFQYVTLIGGQLLA+LV+ +QQ L AEL Sbjct: 134 FQGLSVGGEYGTSATYMSEVALEGRKGFFASFQYVTLIGGQLLALLVVVILQQVLDDAEL 193 Query: 204 MAWGWRIPFVLGAVGALVAMYLRSSLAETSSAGARKKKDAGTIKGLLQHKRAFLNVVGFT 263 AWGWRIPF LGAV A+VA++LR L ETS R K+AG++KGL ++++AFL V+GFT Sbjct: 194 RAWGWRIPFALGAVLAVVALWLRRQLDETSKHETRALKEAGSLKGLWRNRKAFLMVLGFT 253 Query: 264 AGGSLMFYTFTTYMQKYLVNTAGMDPKMANGVMTGALFVYMILQPIFGAISDKIGRRNSM 323 A GSL FYTFTTYMQKYLVNTAGM +A+G+MT AL V+M++QP+FGA+SDKIGRR SM Sbjct: 254 AAGSLCFYTFTTYMQKYLVNTAGMHANVASGIMTAALCVFMLVQPLFGALSDKIGRRTSM 313 Query: 324 LCFSFLGMVCTFPILHFLKDVSSPGVAMALAILALTIVSFYTSISGLIKAEMFPPEVRAL 383 LCF L + T PIL L++V+SP A AL I AL IVSFYTSISG++KAEMFP +VRAL Sbjct: 314 LCFGALATLFTVPILSALQNVTSPYAAFALVICALLIVSFYTSISGILKAEMFPAQVRAL 373 Query: 384 GVGLSYAVGNAIFGGSAEFVALSLKSVGVESAFYWYVSALCLVALIISLRMPDPQRDGHL 443 GVGLSYAV NA+FGGSAE+VALSLKSVG+ES+F+WYV+A+ ++A ++SL + H Sbjct: 374 GVGLSYAVANALFGGSAEYVALSLKSVGMESSFFWYVTAMAVLAFLVSLML-------HR 426 Query: 444 KGD 446 KG Sbjct: 427 KGK 429 >kgtP [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 432 Score = 565 bits (1456), Expect = e-161, Method: Compositional matrix adjust. Identities = 294/433 (67%), Positives = 352/433 (81%), Gaps = 7/433 (1%) Query: 14 PSATTASTPLSAAEYRKRIFAILGASSGNLVEWFDFYVYSFCAIYFAPAFFPKGDATSQL 73 S TA + L++++ R+RI+AI+GASSGNLVEWFDFYVYSFC++YFA FFP G+ T+QL Sbjct: 3 ESTVTADSKLTSSDTRRRIWAIVGASSGNLVEWFDFYVYSFCSLYFAHIFFPSGNTTTQL 62 Query: 74 LNTAGVFAAGFLMRPIGGWLFGRIADKHGRKTSMLISVLMMCGGSLAVAIMPTYATIGAW 133 L TAGVFAAGFLMRPIGGWLFGRIADKHGRK SML+SV MMC GSL +A +P Y TIG W Sbjct: 63 LQTAGVFAAGFLMRPIGGWLFGRIADKHGRKKSMLLSVCMMCFGSLVIACLPGYETIGTW 122 Query: 134 APALLLLARLFQGLSVGGEYGTSATYMSEVAPNGRRGFFASFQYVTLIGGQLLAVLVLFA 193 APALLLLARLFQGLSVGGEYGTSATYMSEVA GR+GF+ASFQYVTLIGGQLLA+LV+ Sbjct: 123 APALLLLARLFQGLSVGGEYGTSATYMSEVAVEGRKGFYASFQYVTLIGGQLLALLVVVV 182 Query: 194 MQQWLSKAELMAWGWRIPFVLGAVGALVAMYLRSSLAETSSAGARKKKDAGTIKGLLQHK 253 +Q + A L WGWRIPF LGAV A+VA++LR L ETS R K+AG++KGL +++ Sbjct: 183 LQHTMEDAALREWGWRIPFALGAVLAVVALWLRRQLDETSQQETRALKEAGSLKGLWRNR 242 Query: 254 RAFLNVVGFTAGGSLMFYTFTTYMQKYLVNTAGMDPKMANGVMTGALFVYMILQPIFGAI 313 RAF+ V+GFTA GSL FYTFTTYMQKYLVNTAGM +A+G+MT ALFV+M++QP+ GA+ Sbjct: 243 RAFIMVLGFTAAGSLCFYTFTTYMQKYLVNTAGMHANVASGIMTAALFVFMLIQPLIGAL 302 Query: 314 SDKIGRRNSMLCFSFLGMVCTFPILHFLKDVSSPGVAMALAILALTIVSFYTSISGLIKA 373 SDKIGRR SMLCF L + T PIL L++VSSP A L + AL IVSFYTSISG++KA Sbjct: 303 SDKIGRRTSMLCFGSLAAIFTVPILSALQNVSSPYAAFGLVMCALLIVSFYTSISGILKA 362 Query: 374 EMFPPEVRALGVGLSYAVGNAIFGGSAEFVALSLKSVGVESAFYWYVSALCLVALIISLR 433 EMFP +VRALGVGLSYAV NAIFGGSAE+VALSLKS+G+E+AF+WYV+ + +VA ++SL Sbjct: 363 EMFPAQVRALGVGLSYAVANAIFGGSAEYVALSLKSIGMETAFFWYVTLMAVVAFLVSLM 422 Query: 434 MPDPQRDGHLKGD 446 + H KG Sbjct: 423 L-------HRKGK 428 >ECs3454 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 432 Score = 564 bits (1453), Expect = e-160, Method: Compositional matrix adjust. Identities = 293/433 (67%), Positives = 352/433 (81%), Gaps = 7/433 (1%) Query: 14 PSATTASTPLSAAEYRKRIFAILGASSGNLVEWFDFYVYSFCAIYFAPAFFPKGDATSQL 73 S TA + L++++ R+RI+AI+GASSGNLVEWFDFYVYSFC++YFA FFP G+ T+QL Sbjct: 3 ESTVTADSKLTSSDTRRRIWAIVGASSGNLVEWFDFYVYSFCSLYFAHIFFPSGNTTTQL 62 Query: 74 LNTAGVFAAGFLMRPIGGWLFGRIADKHGRKTSMLISVLMMCGGSLAVAIMPTYATIGAW 133 L TAGVFAAGFLMRPIGGWLFGRIADKHGRK SML+SV MMC GSL +A +P Y TIG W Sbjct: 63 LQTAGVFAAGFLMRPIGGWLFGRIADKHGRKKSMLLSVCMMCFGSLVIACLPGYETIGTW 122 Query: 134 APALLLLARLFQGLSVGGEYGTSATYMSEVAPNGRRGFFASFQYVTLIGGQLLAVLVLFA 193 APALLLLARLFQGLSVGGEYGTSATYMSEVA GR+GF+ASFQYVTLIGGQLLA+LV+ Sbjct: 123 APALLLLARLFQGLSVGGEYGTSATYMSEVAVEGRKGFYASFQYVTLIGGQLLALLVVVV 182 Query: 194 MQQWLSKAELMAWGWRIPFVLGAVGALVAMYLRSSLAETSSAGARKKKDAGTIKGLLQHK 253 +Q + + L WGWRIPF LGAV A+VA++LR L ETS R K+AG++KGL +++ Sbjct: 183 LQHTMEDSALREWGWRIPFALGAVLAVVALWLRRQLDETSQQETRALKEAGSLKGLWRNR 242 Query: 254 RAFLNVVGFTAGGSLMFYTFTTYMQKYLVNTAGMDPKMANGVMTGALFVYMILQPIFGAI 313 RAF+ V+GFTA GSL FYTFTTYMQKYLVNTAGM +A+G+MT ALFV+M++QP+ GA+ Sbjct: 243 RAFIMVLGFTAAGSLCFYTFTTYMQKYLVNTAGMHANVASGIMTAALFVFMLIQPLIGAL 302 Query: 314 SDKIGRRNSMLCFSFLGMVCTFPILHFLKDVSSPGVAMALAILALTIVSFYTSISGLIKA 373 SDKIGRR SMLCF L + T PIL L++VSSP A L + AL IVSFYTSISG++KA Sbjct: 303 SDKIGRRTSMLCFGSLAAIFTVPILSALQNVSSPYAAFGLVMCALLIVSFYTSISGILKA 362 Query: 374 EMFPPEVRALGVGLSYAVGNAIFGGSAEFVALSLKSVGVESAFYWYVSALCLVALIISLR 433 EMFP +VRALGVGLSYAV NAIFGGSAE+VALSLKS+G+E+AF+WYV+ + +VA ++SL Sbjct: 363 EMFPAQVRALGVGLSYAVANAIFGGSAEYVALSLKSIGMETAFFWYVTLMAVVAFLVSLM 422 Query: 434 MPDPQRDGHLKGD 446 + H KG Sbjct: 423 L-------HRKGK 428