BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.3319.p (212 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value cynT [P] COG0288 Carbonic anhydrase Eco Escherichia coli K12 320 1e-87 ZcynT [P] COG0288 Carbonic anhydrase EcZ Escherichia coli O157:H... 320 1e-87 ECs0392 [P] COG0288 Carbonic anhydrase Ecs Escherichia coli O157:H7 317 9e-87 PA2053 [P] COG0288 Carbonic anhydrase Pae Pseudomonas aeruginosa 313 1e-85 PA0102 [P] COG0288 Carbonic anhydrase Pae Pseudomonas aeruginosa 224 1e-58 >cynT [P] COG0288 Carbonic anhydrase Eco Escherichia coli K12 Length = 219 Score = 320 bits (821), Expect = 1e-87, Method: Compositional matrix adjust. Identities = 147/206 (71%), Positives = 175/206 (84%) Query: 1 MRDIINGFLRFQQDVFPSRKELFKSLANGQTPTALFISCSDSRMVPELVTQREPGDLFVI 60 M++II+GFL+FQ++ FP R+ LFK LA Q+P LFISCSDSR+VPELVTQREPGDLFVI Sbjct: 1 MKEIIDGFLKFQREAFPKREALFKQLATQQSPRTLFISCSDSRLVPELVTQREPGDLFVI 60 Query: 61 RNAGNIVPSFGPEPGGVSASVEYAVAQLKVSDIVICGHSDCGAMTAVATCACLDHMPAVR 120 RNAGNIVPS+GPEPGGVSASVEYAVA L+VSDIVICGHS+CGAMTA+A+C C+DHMPAV Sbjct: 61 RNAGNIVPSYGPEPGGVSASVEYAVAALRVSDIVICGHSNCGAMTAIASCQCMDHMPAVS 120 Query: 121 NWLHHTDAARMINESRHHETEKDRIDGMVRENVIAQLNNIRTHPSVAVALAQGRLALHGW 180 +WL + D+AR++NE+R H + MVRENVIAQL N++THPSV +AL +GR+ALHGW Sbjct: 121 HWLRYADSARVVNEARPHSDLPSKAAAMVRENVIAQLANLQTHPSVRLALEEGRIALHGW 180 Query: 181 VYDIESGSILAHDTATNTFVPLALHP 206 VYDIESGSI A D AT FVPLA +P Sbjct: 181 VYDIESGSIAAFDGATRQFVPLAANP 206 >ZcynT [P] COG0288 Carbonic anhydrase EcZ Escherichia coli O157:H7 EDL933 Length = 219 Score = 320 bits (821), Expect = 1e-87, Method: Compositional matrix adjust. Identities = 147/206 (71%), Positives = 175/206 (84%) Query: 1 MRDIINGFLRFQQDVFPSRKELFKSLANGQTPTALFISCSDSRMVPELVTQREPGDLFVI 60 M++II+GFL+FQ++ FP R+ LFK LA Q+P LFISCSDSR+VPELVTQREPGDLFVI Sbjct: 1 MKEIIDGFLKFQREAFPKREALFKQLATQQSPRTLFISCSDSRLVPELVTQREPGDLFVI 60 Query: 61 RNAGNIVPSFGPEPGGVSASVEYAVAQLKVSDIVICGHSDCGAMTAVATCACLDHMPAVR 120 RNAGNIVPS+GPEPGGVSASVEYAVA L+VSDIVICGHS+CGAMTA+A+C C+DHMPAV Sbjct: 61 RNAGNIVPSYGPEPGGVSASVEYAVAALRVSDIVICGHSNCGAMTAIASCQCMDHMPAVS 120 Query: 121 NWLHHTDAARMINESRHHETEKDRIDGMVRENVIAQLNNIRTHPSVAVALAQGRLALHGW 180 +WL + D+AR++NE+R H + MVRENVIAQL N++THPSV +AL +GR+ALHGW Sbjct: 121 HWLRYADSARVVNEARPHSDLPSKAAAMVRENVIAQLANLQTHPSVRLALEEGRIALHGW 180 Query: 181 VYDIESGSILAHDTATNTFVPLALHP 206 VYDIESGSI A D AT FVPLA +P Sbjct: 181 VYDIESGSIAAFDGATRQFVPLAANP 206 >ECs0392 [P] COG0288 Carbonic anhydrase Ecs Escherichia coli O157:H7 Length = 219 Score = 317 bits (813), Expect = 9e-87, Method: Compositional matrix adjust. Identities = 146/206 (70%), Positives = 174/206 (84%) Query: 1 MRDIINGFLRFQQDVFPSRKELFKSLANGQTPTALFISCSDSRMVPELVTQREPGDLFVI 60 M++II+GFL+FQ++ FP R+ LFK LA Q+P LFISCSDSR+VPELVTQREPGDLF I Sbjct: 1 MKEIIDGFLKFQREAFPKREALFKQLATQQSPRTLFISCSDSRLVPELVTQREPGDLFGI 60 Query: 61 RNAGNIVPSFGPEPGGVSASVEYAVAQLKVSDIVICGHSDCGAMTAVATCACLDHMPAVR 120 RNAGNIVPS+GPEPGGVSASVEYAVA L+VSDIVICGHS+CGAMTA+A+C C+DHMPAV Sbjct: 61 RNAGNIVPSYGPEPGGVSASVEYAVAALRVSDIVICGHSNCGAMTAIASCQCMDHMPAVS 120 Query: 121 NWLHHTDAARMINESRHHETEKDRIDGMVRENVIAQLNNIRTHPSVAVALAQGRLALHGW 180 +WL + D+AR++NE+R H + MVRENVIAQL N++THPSV +AL +GR+ALHGW Sbjct: 121 HWLRYADSARVVNEARPHSDLPSKAAAMVRENVIAQLANLQTHPSVRLALEEGRIALHGW 180 Query: 181 VYDIESGSILAHDTATNTFVPLALHP 206 VYDIESGSI A D AT FVPLA +P Sbjct: 181 VYDIESGSIAAFDGATRQFVPLAANP 206 >PA2053 [P] COG0288 Carbonic anhydrase Pae Pseudomonas aeruginosa Length = 220 Score = 313 bits (803), Expect = 1e-85, Method: Compositional matrix adjust. Identities = 146/206 (70%), Positives = 169/206 (82%) Query: 1 MRDIINGFLRFQQDVFPSRKELFKSLANGQTPTALFISCSDSRMVPELVTQREPGDLFVI 60 MRDII+GFLRFQ+D +P+R +LFKSLA Q P ALFI+CSDSR+VPEL+TQREPG+LFVI Sbjct: 1 MRDIIDGFLRFQRDAYPARSQLFKSLATRQAPKALFIACSDSRVVPELLTQREPGELFVI 60 Query: 61 RNAGNIVPSFGPEPGGVSASVEYAVAQLKVSDIVICGHSDCGAMTAVATCACLDHMPAVR 120 RNAGNIVP +GP+PGGVSASVEYAVA L V DIV+CGHSDCGAM A+A+CACLD +PAV Sbjct: 61 RNAGNIVPGYGPQPGGVSASVEYAVAVLGVGDIVVCGHSDCGAMGAIASCACLDQLPAVA 120 Query: 121 NWLHHTDAARMINESRHHETEKDRIDGMVRENVIAQLNNIRTHPSVAVALAQGRLALHGW 180 WLHH +AAR +N + H +E R+D +VR NVIAQL N+RTHP VA AL QGRL LHGW Sbjct: 121 GWLHHAEAARAMNSAHEHASEAARLDALVRHNVIAQLANLRTHPCVARALEQGRLNLHGW 180 Query: 181 VYDIESGSILAHDTATNTFVPLALHP 206 VYDIESG I A D A+ FV LA HP Sbjct: 181 VYDIESGRIDALDGASRRFVSLAEHP 206 >PA0102 [P] COG0288 Carbonic anhydrase Pae Pseudomonas aeruginosa Length = 242 Score = 224 bits (571), Expect = 1e-58, Method: Compositional matrix adjust. Identities = 105/203 (51%), Positives = 142/203 (69%), Gaps = 1/203 (0%) Query: 1 MRDIINGFLRFQQDVFPSRKELFKSLANGQTPTALFISCSDSRMVPELVTQREPGDLFVI 60 ++ I++GF F+++VFP ++ LFK LAN Q P A+FI+C+DSR+VPEL+TQ PGDLFV Sbjct: 22 LKRIVDGFQHFRREVFPEQQALFKKLANSQRPRAMFITCADSRIVPELITQSSPGDLFVT 81 Query: 61 RNAGNIVPSFGPEPGGVSASVEYAVAQLKVSDIVICGHSDCGAMTAVATCACLDHMPAVR 120 RN GN+VP +G GGVS ++EYAV L V I++CGHSDCGAM AV L+ MP V+ Sbjct: 82 RNVGNVVPPYGQMNGGVSTAIEYAVLALGVHHIIVCGHSDCGAMRAVLDPQTLERMPTVK 141 Query: 121 NWLHHTDAAR-MINESRHHETEKDRIDGMVRENVIAQLNNIRTHPSVAVALAQGRLALHG 179 WL H + AR ++ ++ D + + ENV+AQL+++RTHPSVA LA G+L +HG Sbjct: 142 AWLRHAEVARTVVADNCDCGASHDTLGVLTEENVVAQLDHLRTHPSVASRLASGQLFIHG 201 Query: 180 WVYDIESGSILAHDTATNTFVPL 202 WVYDIES I A+D F+PL Sbjct: 202 WVYDIESAQIRAYDAKQGRFLPL 224