BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.3231.p (388 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1148 Non COG 387 e-107 PA2630 [S] COG2850 Uncharacterized conserved protein Pae Pseudom... 256 8e-68 STM1229 [S] COG2850 Uncharacterized conserved protein Sty Salmon... 217 4e-56 ycfD [S] COG2850 Uncharacterized conserved protein Eco Escherich... 215 1e-55 ZycfD [S] COG2850 Uncharacterized conserved protein EcZ Escheric... 215 2e-55 >RSc1148 Non COG Length = 409 Score = 387 bits (995), Expect = e-107, Method: Compositional matrix adjust. Identities = 202/397 (50%), Positives = 264/397 (66%), Gaps = 14/397 (3%) Query: 2 ACRRVSPPIMATMKKLDLLGGITPAQFLRDYWHKKPLLIRNAIP-----GFTAPLPRQEL 56 A R P +A + LLGG++P F+R +W KKPLLIR A+ PL L Sbjct: 8 AAARGVQPGLAAGRPAQLLGGLSPRDFMRTHWQKKPLLIRQALSPEDMRALHFPLSPDAL 67 Query: 57 FDLARRDEVESRLITHRSDGWDMQHGPFNK--LPPLKQKAWTLLVQGVNLHHPAADALLR 114 LARR++VESRLI W HGPFN+ LP K + WTLLVQGVNL PA DAL++ Sbjct: 68 IKLARREDVESRLIAQTRGRWTFNHGPFNERPLPSRKARNWTLLVQGVNLVEPAVDALMQ 127 Query: 115 QFRFVPDARLDDLMISYATDGGGVGPHFDSYDVFLLQAHGQRRWRISAQDDLTLEEGVPL 174 +FRF+PDARLDD+MIS+ATDGGGVGPHFDSYDVFLLQAHG+RRWRIS+Q+DLTL +PL Sbjct: 128 RFRFIPDARLDDVMISFATDGGGVGPHFDSYDVFLLQAHGRRRWRISSQNDLTLVPDLPL 187 Query: 175 KILSHFQAEQEFVLEPGDMLYLPPHYAHDGVAVGECMTYSIGFRAPTYQELGESFLEFMM 234 KIL++F E+EF+LEPGDMLYLPPHYAHDGVA G+CMTYS+GFR+P+Y+EL FL F+ Sbjct: 188 KILANFTPEEEFILEPGDMLYLPPHYAHDGVAEGDCMTYSVGFRSPSYRELAGHFLGFLS 247 Query: 235 DTI----DLPGRYADPDLKTSAKPAELQLDMLTRIREELNKIRFTDDDITIFLGQHLSEP 290 T+ D GRY DP+ K +P EL M+ + ++LN +R+T + + F G +L+EP Sbjct: 248 QTLEDNPDFEGRYTDPEQKPVERPGELPTAMVRALAQKLNALRWTPELVGEFFGAYLTEP 307 Query: 291 KPSVFFEAPTEEMSFARFFQGAKKRGLVLHRKTRMLYRGSHVFINGESFQVGRADKVILA 350 K V F +S ARF A+K G+VL +T+ LY +ING++F+ L+ Sbjct: 308 KDHVEF-VTQPRLSLARFTARARKEGIVLDARTQALYDAQRFWINGDTFEPSDTLLAWLS 366 Query: 351 KLADHRTLEKTDFAQASE--DLLEALHQWHESGWLEI 385 L+D R A++ DL++ LH W+E GWL++ Sbjct: 367 ALSDQRGASAEAVDAAADLPDLMDTLHAWYEEGWLQL 403 >PA2630 [S] COG2850 Uncharacterized conserved protein Pae Pseudomonas aeruginosa Length = 389 Score = 256 bits (653), Expect = 8e-68, Method: Compositional matrix adjust. Identities = 160/390 (41%), Positives = 221/390 (56%), Gaps = 19/390 (4%) Query: 11 MATMKKLDLLGGITPAQFLRDYWHKKPLLIRNAIPGFTAPLPRQELFDLARRDEVESRLI 70 M L LLGG+T A+FLRDYW +KPLL+R AIP F +PL EL L+ + VESR++ Sbjct: 1 MNADTPLQLLGGLTAAEFLRDYWQRKPLLVRQAIPDFESPLSADELAGLSLEESVESRIV 60 Query: 71 -THRSDGWDMQHGPFNK--LPPLKQKAWTLLVQGVNLHHPAADALLRQFRFVPDARLDDL 127 H W+M+ GPF + L ++ WTLLVQ V+ P LL QFRF+P R+DD+ Sbjct: 61 LEHGKTPWEMRRGPFQEEDYQHLPEQDWTLLVQAVDQFVPEVAQLLEQFRFLPSWRIDDV 120 Query: 128 MISYATDGGGVGPHFDSYDVFLLQAHGQRRWRIS--AQDDLTLEEGVPLKILSHFQAEQE 185 MISYA GGGVGPHFD+YDVFLLQ HG+RRW++ D L E L+IL+ F+ E Sbjct: 121 MISYAAPGGGVGPHFDNYDVFLLQGHGRRRWKVGQMCSSDSPLREHADLRILADFEQSDE 180 Query: 186 FVLEPGDMLYLPPHYAHDGVAVGECMTYSIGFRAPTYQELGESFLEFMMDTIDLPGRYAD 245 +VLEPGDMLYLPP AH G+A ECMTYSIGFRAP+ E+ F +F+ + RY D Sbjct: 181 WVLEPGDMLYLPPRLAHYGIAEDECMTYSIGFRAPSAAEVLTHFTDFLGQFLSDEERYTD 240 Query: 246 PDLK-TSAKPAELQLDMLTRIREELNKIRFTDDDITIFLGQHLSEPK-PSVFF--EAPTE 301 L+ P ++Q D L R++ + + + + + GQ ++EP+ P + E P E Sbjct: 241 AGLQPVGDDPHQIQRDALERLQGLIQEHMSDERLLLTWFGQFMTEPRYPELVAGEEIPEE 300 Query: 302 EMSFARFFQGAKKRGLVLHRKTRMLYR----GSHVFINGESFQVGRADKVILAKLADHRT 357 E+ F GA LV + R+ + G +F +G+S + K +L + Sbjct: 301 EL-FGALEDGAL---LVRNPSARLAWSEIDIGLVLFASGQSVLLPGQLKELLKLVCSADA 356 Query: 358 LEKTDFAQ--ASEDLLEALHQWHESGWLEI 385 L + Q A +D + L + + G LE Sbjct: 357 LHLENLGQWLADDDARKLLAELVKQGSLEF 386 >STM1229 [S] COG2850 Uncharacterized conserved protein Sty Salmonella typhimurium LT2 Length = 373 Score = 217 bits (552), Expect = 4e-56, Method: Compositional matrix adjust. Identities = 125/347 (36%), Positives = 188/347 (54%), Gaps = 10/347 (2%) Query: 28 FLRDYWHKKPLLIRNAIPGFTAPLPRQELFDLARRDEVESRLITHRSDGWDMQHGPFNKL 87 FL +W K+P++++ F PL EL LA E++SRL++H+ W + HGPF Sbjct: 12 FLERHWQKRPVVLKRGFSNFIDPLSPDELAGLAMESEIDSRLVSHQDGKWQVSHGPFESY 71 Query: 88 PPLKQKAWTLLVQGVNLHHPAADALLRQFRFVPDARLDDLMISYATDGGGVGPHFDSYDV 147 L + W+LLVQ VN H AL+R FR +PD R+DDLMIS++ GGGVGPH D YDV Sbjct: 72 DHLGESNWSLLVQAVNHWHEPTAALMRPFRALPDWRIDDLMISFSVPGGGVGPHLDQYDV 131 Query: 148 FLLQAHGQRRWRISAQDDLTLEEGVP---LKILSHFQAEQEFVLEPGDMLYLPPHYAHDG 204 F++Q G+RRWR+ + L + + P L + F+A + LEPGD+LY+PP + H+G Sbjct: 132 FIIQGTGRRRWRVGEK--LQMRQHCPHPDLLQVEPFEAIIDEELEPGDILYIPPGFPHEG 189 Query: 205 VAVGECMTYSIGFRAPTYQELGESFLEFMMDTIDLPGRYADPDLKTSAKPAELQLDMLTR 264 A+ M YS+GFRAP +EL F ++++ Y+DPD+ + PA++ + + Sbjct: 190 YALENAMNYSVGFRAPNSRELISGFADYVLQRELGNTYYSDPDMPSRKHPADILPQEMDK 249 Query: 265 IREELNKIRFTDDDITIFLGQHLSEPKPSVFFEAPTEEMSFARFFQGAKKRGLVLHR--K 322 +R + + +LG+ LS+ + + P + A K+G VL R Sbjct: 250 LRNMMLDLINQPAHFQQWLGEFLSQSRHELDIAPPEPPYQPDEIYD-ALKQGEVLVRLGG 308 Query: 323 TRMLYRGSHVFINGESFQVGRADKVILAKLADHRTLEKTDFAQASED 369 R+L G V+ NGE ++ + L LA H L +F A ED Sbjct: 309 LRVLRIGDEVYANGE--KIDSPHRPALEALASHIALTAENFGDALED 353 >ycfD [S] COG2850 Uncharacterized conserved protein Eco Escherichia coli K12 Length = 376 Score = 215 bits (548), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 126/347 (36%), Positives = 192/347 (55%), Gaps = 10/347 (2%) Query: 28 FLRDYWHKKPLLIRNAIPGFTAPLPRQELFDLARRDEVESRLITHRSDGWDMQHGPFNKL 87 FL +W K+P++++ F P+ EL LA EV+SRL++H+ W + HGPF Sbjct: 15 FLERHWQKRPVVLKRGFNNFIDPISPDELAGLAMESEVDSRLVSHQDGKWQVSHGPFESY 74 Query: 88 PPLKQKAWTLLVQGVNLHHPAADALLRQFRFVPDARLDDLMISYATDGGGVGPHFDSYDV 147 L + W+LLVQ VN H AL+R FR +PD R+DDLMIS++ GGGVGPH D YDV Sbjct: 75 DHLGETNWSLLVQAVNHWHEPTAALMRPFRELPDWRIDDLMISFSVPGGGVGPHLDQYDV 134 Query: 148 FLLQAHGQRRWRISAQDDLTLEEGVP---LKILSHFQAEQEFVLEPGDMLYLPPHYAHDG 204 F++Q G+RRWR+ + L +++ P L + F+A + LEPGD+LY+PP + H+G Sbjct: 135 FIIQGTGRRRWRVGEK--LQMKQHCPHPDLLQVDPFEAIIDEELEPGDILYIPPGFPHEG 192 Query: 205 VAVGECMTYSIGFRAPTYQELGESFLEFMMDTIDLPGRYADPDLKTSAKPAELQLDMLTR 264 A+ M YS+GFRAP +EL F ++++ Y+DPD+ A PA++ + + Sbjct: 193 YALENAMNYSVGFRAPNTRELISGFADYVLQRELGGNYYSDPDVPPRAHPADVLPQEMDK 252 Query: 265 IREELNKIRFTDDDITIFLGQHLSEPKPSVFFEAPTEEMSFARFFQGAKKRGLVLHR--K 322 +RE + ++ + + G+ +S+ + + AP E A K+G VL R Sbjct: 253 LREMMLELINQPEHFKQWFGEFISQSRHELDI-APPEPPYQPDEIYDALKQGEVLVRLGG 311 Query: 323 TRMLYRGSHVFINGESFQVGRADKVILAKLADHRTLEKTDFAQASED 369 R+L G V+ NGE ++ + L LA + L +F A ED Sbjct: 312 LRVLRIGDDVYANGE--KIDSPHRPALDALASNIALTAENFGDALED 356 >ZycfD [S] COG2850 Uncharacterized conserved protein EcZ Escherichia coli O157:H7 EDL933 Length = 376 Score = 215 bits (547), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 124/347 (35%), Positives = 191/347 (55%), Gaps = 10/347 (2%) Query: 28 FLRDYWHKKPLLIRNAIPGFTAPLPRQELFDLARRDEVESRLITHRSDGWDMQHGPFNKL 87 FL +W K+P++++ F P+ EL LA EV+SRL++H+ W + HGPF Sbjct: 15 FLERHWQKRPVVLKRGFNNFIDPISPDELAGLAMESEVDSRLVSHQDGKWQVSHGPFESY 74 Query: 88 PPLKQKAWTLLVQGVNLHHPAADALLRQFRFVPDARLDDLMISYATDGGGVGPHFDSYDV 147 L + W+LLVQ VN H AL+R FR +PD R+DDLMIS++ GGGVGPH D YDV Sbjct: 75 DHLGETNWSLLVQAVNHWHEPTAALMRPFRELPDWRIDDLMISFSVPGGGVGPHLDQYDV 134 Query: 148 FLLQAHGQRRWRISAQDDLTLEEGVP---LKILSHFQAEQEFVLEPGDMLYLPPHYAHDG 204 F++Q G+RRWR+ + L +++ P L + F+A + LEPGD+LY+PP + H+G Sbjct: 135 FIIQGTGRRRWRVGEK--LQMKQHCPHPDLLQVDPFEAIIDEELEPGDILYIPPGFPHEG 192 Query: 205 VAVGECMTYSIGFRAPTYQELGESFLEFMMDTIDLPGRYADPDLKTSAKPAELQLDMLTR 264 A+ M YS+GFRAP +EL F ++++ Y+DPD+ A PA++ + + Sbjct: 193 YALENAMNYSVGFRAPNTRELISGFADYVLQRELGGNYYSDPDVPPRAHPADVLPQEMDK 252 Query: 265 IREELNKIRFTDDDITIFLGQHLSEPKPSVFFEAPTEEMSFARFFQGAKKRGLVLHR--K 322 +RE + ++ + + G+ +S+ + + P + A K+G VL R Sbjct: 253 LREMMLELINQPEHFKQWFGEFISQSRHELDIAPPEPPYQPDEIYD-ALKQGDVLVRLGG 311 Query: 323 TRMLYRGSHVFINGESFQVGRADKVILAKLADHRTLEKTDFAQASED 369 R+L G V+ NGE ++ + L LA + L +F A ED Sbjct: 312 LRVLRIGDDVYTNGE--KIDSPHRPALDALASNIALTAENFGDALED 356