BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.3170.p (294 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2109 [GER] COG0697 Permeases of the drug/metabolite transport... 396 e-110 ZyddG [GER] COG0697 Permeases of the drug/metabolite transporter... 337 2e-92 ECs2077 [GER] COG0697 Permeases of the drug/metabolite transport... 337 2e-92 yddG [GER] COG0697 Permeases of the drug/metabolite transporter ... 336 4e-92 STM1571 [GER] COG0697 Permeases of the drug/metabolite transport... 285 7e-77 >RSc2109 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rso Ralstonia solanacearum Length = 316 Score = 396 bits (1017), Expect = e-110, Method: Compositional matrix adjust. Identities = 202/295 (68%), Positives = 244/295 (82%), Gaps = 2/295 (0%) Query: 1 MESK-KATLIGLSAVLLWSAIVGLIRGVSQHLGATGGAAAIYTVASVILWMSVGFPRLSR 59 M+SK KATLIGL AV+LWS+IVGL+RGVS LGA GGAA +YTV S+ L SVGF +++ Sbjct: 1 MQSKRKATLIGLIAVVLWSSIVGLLRGVSASLGAVGGAAMMYTVVSIFLLFSVGFIKVNA 60 Query: 60 FPRKYLLWGSALFVAYELCLSLSIGYAHSARQAIEVGMVNYLWPTFTLVAAILFGGQRAT 119 FPR+YL+WGS LFV+YELCLSLSIGYA+S RQAIEVGMVNYLWPTFT++ AI F Q + Sbjct: 61 FPRRYLVWGSILFVSYELCLSLSIGYANSDRQAIEVGMVNYLWPTFTMLFAIAFNRQPSN 120 Query: 120 LLVVPGFVLSMLGICWVLGGEQGLDLAGMMANLQDNPLSYGLAFVGALIWAAYCTVTATL 179 LL++PG ++++LGIC VLGG+QGLD AGM AN+QDNPLSYGLA GALIWAAYC VT+ + Sbjct: 121 LLIIPGVLVAILGICQVLGGDQGLDFAGMAANIQDNPLSYGLALSGALIWAAYCAVTSRM 180 Query: 180 AQGSNGVTPFFILVALALWGKFLLGDHAGELVLSLPALIYLVLAAAAMGLGYAAWNVGIL 239 A+G NG+T FF+L ALALW K+ L G + S A++YLV+AA AMG GYAAWNVGIL Sbjct: 181 AEGKNGITLFFMLTALALWIKY-LATGGGAMHFSYQAILYLVMAACAMGFGYAAWNVGIL 239 Query: 240 HGNVTLLAGASYFIPVFSSALSALLLRAPLPASFWVGAALVCGGSILCWRATAGR 294 HGNVT+LAGASYFIPVFS+AL+A LLR PL ++FW GA++VC GSILCW AT G+ Sbjct: 240 HGNVTVLAGASYFIPVFSAALAATLLRTPLSSAFWKGASMVCAGSILCWLATRGQ 294 >ZyddG [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 293 Score = 337 bits (863), Expect = 2e-92, Method: Compositional matrix adjust. Identities = 170/291 (58%), Positives = 220/291 (75%), Gaps = 1/291 (0%) Query: 1 MESKKATLIGLSAVLLWSAIVGLIRGVSQHLGATGGAAAIYTVASVILWMSVGFPRLSRF 60 M +KATLIGL A++LWS +VGLIRGVS+ LG GGAAAIY+++ ++L +VGFPR+ + Sbjct: 1 MTRQKATLIGLIAIVLWSTMVGLIRGVSEGLGPVGGAAAIYSLSGLLLIFTVGFPRIRQI 60 Query: 61 PRKYLLWGSALFVAYELCLSLSIGYAHSARQAIEVGMVNYLWPTFTLVAAILFGGQRATL 120 P+ YLL GS LFV+YE+CL+LS+GYA + QAIEVGMVNYLWP+ T++ AILF GQ+ Sbjct: 61 PKGYLLAGSLLFVSYEICLALSLGYAATRHQAIEVGMVNYLWPSLTILFAILFNGQKTNW 120 Query: 121 LVVPGFVLSMLGICWVLGGEQGLDLAGMMANLQDNPLSYGLAFVGALIWAAYCTVTATLA 180 L+VPG +L+++G+CWVLGG+ GL ++ N+ +PLSY LAF+GA IWAAYCTVT A Sbjct: 121 LIVPGLLLALVGVCWVLGGDNGLHYDEIINNITTSPLSYFLAFIGAFIWAAYCTVTNKYA 180 Query: 181 QGSNGVTPFFILVALALWGKFLLGDHAGELVLSLPALIYLVLAAAAMGLGYAAWNVGILH 240 +G NG+T F +L +LW + L E+V S P +I L+ AA +G YAAWNVGILH Sbjct: 181 RGFNGITVFVLLTGASLWVYYFLTPQP-EMVFSTPVMIKLISAAFTLGFAYAAWNVGILH 239 Query: 241 GNVTLLAGASYFIPVFSSALSALLLRAPLPASFWVGAALVCGGSILCWRAT 291 GNVT++A SYF PV SSAL+A+LL APL SFW GA +VCGGS+LCW AT Sbjct: 240 GNVTIMAVGSYFTPVLSSALAAVLLSAPLSFSFWQGALMVCGGSLLCWLAT 290 >ECs2077 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Ecs Escherichia coli O157:H7 Length = 293 Score = 337 bits (863), Expect = 2e-92, Method: Compositional matrix adjust. Identities = 170/291 (58%), Positives = 220/291 (75%), Gaps = 1/291 (0%) Query: 1 MESKKATLIGLSAVLLWSAIVGLIRGVSQHLGATGGAAAIYTVASVILWMSVGFPRLSRF 60 M +KATLIGL A++LWS +VGLIRGVS+ LG GGAAAIY+++ ++L +VGFPR+ + Sbjct: 1 MTRQKATLIGLIAIVLWSTMVGLIRGVSEGLGPVGGAAAIYSLSGLLLIFTVGFPRIRQI 60 Query: 61 PRKYLLWGSALFVAYELCLSLSIGYAHSARQAIEVGMVNYLWPTFTLVAAILFGGQRATL 120 P+ YLL GS LFV+YE+CL+LS+GYA + QAIEVGMVNYLWP+ T++ AILF GQ+ Sbjct: 61 PKGYLLAGSLLFVSYEICLALSLGYAATRHQAIEVGMVNYLWPSLTILFAILFNGQKTNW 120 Query: 121 LVVPGFVLSMLGICWVLGGEQGLDLAGMMANLQDNPLSYGLAFVGALIWAAYCTVTATLA 180 L+VPG +L+++G+CWVLGG+ GL ++ N+ +PLSY LAF+GA IWAAYCTVT A Sbjct: 121 LIVPGLLLALVGVCWVLGGDNGLHYDEIINNITTSPLSYFLAFIGAFIWAAYCTVTNKYA 180 Query: 181 QGSNGVTPFFILVALALWGKFLLGDHAGELVLSLPALIYLVLAAAAMGLGYAAWNVGILH 240 +G NG+T F +L +LW + L E+V S P +I L+ AA +G YAAWNVGILH Sbjct: 181 RGFNGITVFVLLTGASLWVYYFLTPQP-EMVFSTPVMIKLISAAFTLGFAYAAWNVGILH 239 Query: 241 GNVTLLAGASYFIPVFSSALSALLLRAPLPASFWVGAALVCGGSILCWRAT 291 GNVT++A SYF PV SSAL+A+LL APL SFW GA +VCGGS+LCW AT Sbjct: 240 GNVTIMAVGSYFTPVLSSALAAVLLSAPLSFSFWQGALMVCGGSLLCWLAT 290 >yddG [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Eco Escherichia coli K12 Length = 293 Score = 336 bits (861), Expect = 4e-92, Method: Compositional matrix adjust. Identities = 169/291 (58%), Positives = 220/291 (75%), Gaps = 1/291 (0%) Query: 1 MESKKATLIGLSAVLLWSAIVGLIRGVSQHLGATGGAAAIYTVASVILWMSVGFPRLSRF 60 M +KATLIGL A++LWS +VGLIRGVS+ LG GGAAAIY+++ ++L +VGFPR+ + Sbjct: 1 MTRQKATLIGLIAIVLWSTMVGLIRGVSEGLGPVGGAAAIYSLSGLLLIFTVGFPRIRQI 60 Query: 61 PRKYLLWGSALFVAYELCLSLSIGYAHSARQAIEVGMVNYLWPTFTLVAAILFGGQRATL 120 P+ YLL GS LFV+YE+CL+LS+GYA + QAIEVGMVNYLWP+ T++ AILF GQ+ Sbjct: 61 PKGYLLAGSLLFVSYEICLALSLGYAATHHQAIEVGMVNYLWPSLTILFAILFNGQKTNW 120 Query: 121 LVVPGFVLSMLGICWVLGGEQGLDLAGMMANLQDNPLSYGLAFVGALIWAAYCTVTATLA 180 L+VPG +L+++G+CWVLGG+ GL ++ N+ +PLSY LAF+GA IWAAYCTVT A Sbjct: 121 LIVPGLLLALVGVCWVLGGDNGLHYDEIINNITTSPLSYFLAFIGAFIWAAYCTVTNKYA 180 Query: 181 QGSNGVTPFFILVALALWGKFLLGDHAGELVLSLPALIYLVLAAAAMGLGYAAWNVGILH 240 +G NG+T F +L +LW + L E++ S P +I L+ AA +G YAAWNVGILH Sbjct: 181 RGFNGITVFVLLTGASLWVYYFLTPQP-EMIFSTPVMIKLISAAFTLGFAYAAWNVGILH 239 Query: 241 GNVTLLAGASYFIPVFSSALSALLLRAPLPASFWVGAALVCGGSILCWRAT 291 GNVT++A SYF PV SSAL+A+LL APL SFW GA +VCGGS+LCW AT Sbjct: 240 GNVTIMAVGSYFTPVLSSALAAVLLSAPLSFSFWQGALMVCGGSLLCWLAT 290 >STM1571 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Sty Salmonella typhimurium LT2 Length = 274 Score = 285 bits (730), Expect = 7e-77, Method: Compositional matrix adjust. Identities = 155/275 (56%), Positives = 203/275 (73%), Gaps = 1/275 (0%) Query: 20 IVGLIRGVSQHLGATGGAAAIYTVASVILWMSVGFPRLSRFPRKYLLWGSALFVAYELCL 79 +VGLIRGVS+ LG GGAA IY+++ ++L +VG P + RFP +YL+ GS LFV+YE+CL Sbjct: 1 MVGLIRGVSEGLGPVGGAAMIYSLSGLLLIFTVGLPDIRRFPGRYLIAGSVLFVSYEICL 60 Query: 80 SLSIGYAHSARQAIEVGMVNYLWPTFTLVAAILFGGQRATLLVVPGFVLSMLGICWVLGG 139 +LS+GYA + QAIEVGMVNYLWP+ T++ AILF GQ+ L+VPG ++++ G+CWVLGG Sbjct: 61 ALSLGYAATRHQAIEVGMVNYLWPSLTILFAILFNGQKTNWLIVPGLLIALTGVCWVLGG 120 Query: 140 EQGLDLAGMMANLQDNPLSYGLAFVGALIWAAYCTVTATLAQGSNGVTPFFILVALALWG 199 E GL+ +++N+ +PLSY LAF+GA IWA YCTVT A+G NG+T F +L A+ALW Sbjct: 121 ENGLNPGEIISNVATSPLSYLLAFLGAFIWATYCTVTNKYARGFNGITVFVLLTAVALWL 180 Query: 200 KFLLGDHAGELVLSLPALIYLVLAAAAMGLGYAAWNVGILHGNVTLLAGASYFIPVFSSA 259 + L ++ SLP + L AA +G YAAWNVGILHGNVT++A SYF PV SSA Sbjct: 181 HYFLTPQPA-MIFSLPVIAKLFTAALTLGFAYAAWNVGILHGNVTIMAVGSYFTPVMSSA 239 Query: 260 LSALLLRAPLPASFWVGAALVCGGSILCWRATAGR 294 L+ALLL +PL SFW GA +VC GS+LCW AT R Sbjct: 240 LAALLLSSPLSFSFWQGAVMVCVGSLLCWLATRRR 274