BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.3144.p (1261 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA3535_1 [O] COG1404 Subtilisin-like serine proteases Pae Pseudo... 335 3e-91 NMA0478_1 [O] COG1404 Subtilisin-like serine proteases NmA Neiss... 121 1e-26 XF0267_1 [O] COG1404 Subtilisin-like serine proteases Xfa Xylell... 117 3e-25 NMB1969_1 [O] COG1404 Subtilisin-like serine proteases Nme Neiss... 116 3e-25 XF1026_1 [O] COG1404 Subtilisin-like serine proteases Xfa Xylell... 107 2e-22 >PA3535_1 [O] COG1404 Subtilisin-like serine proteases Pae Pseudomonas aeruginosa Length = 453 Score = 335 bits (860), Expect = 3e-91, Method: Compositional matrix adjust. Identities = 176/394 (44%), Positives = 252/394 (63%), Gaps = 22/394 (5%) Query: 57 ASWAANSEFKTDWGLGAMNAQYAYAAGFSGLGIKLGSVDSGLLLTHAEFVSRNVKALAVI 116 ASW + +E++ DWGL M A AYAAG G G+K+G +DSG +H + + + + Sbjct: 42 ASWRS-AEYQQDWGLERMRADQAYAAGIDGQGVKIGEMDSGFDPSHPDTPASRYQPVTAS 100 Query: 117 GTYANDGSQYQNGSQPWKAGDAFSTTGAVSTLNDKHGSHVSGSIAAAKNGAGIMGVAFAS 176 GTY + G FS +GA++ ND HG+HV G++ A+++G G+ GVA+A+ Sbjct: 101 GTYVD--------------GTPFSVSGAMNGNNDSHGTHVGGTLGASRDGVGMHGVAYAA 146 Query: 177 DYYITNTNGTDSSVYGVNMDYNYFKAAYGNLASAGVRVINSSWGSPDSRDDFGSIGGVAA 236 Y+ NTN DS ++G D NYFKAAY LA AGVR IN+SWGS + ++ G+ A Sbjct: 147 QVYVANTNQNDSFLFGPTPDPNYFKAAYQALADAGVRAINNSWGSQPKDVSYETLDGLHA 206 Query: 237 AYQRLQGGAKKSWLDAAADVAQASNTLMVWAAGNSSKSNVNIRSALPYFRPELEQNWIAV 296 AY + G + +WLDAAA V++ + V++AGNS +N ++RSALPYF+P+LE +W+AV Sbjct: 207 AYAQHYG--RSTWLDAAAGVSR-QGVINVFSAGNSGYANASVRSALPYFQPDLEGHWLAV 263 Query: 297 AAVNASSVLPSFSNQCGLAKYWCLSAPGSAIPSLNITSDTALVNASGTSMAAPHVTGALG 356 + ++ + N+CG+AKYWC++ PG I S N SGTSMAAPH TGAL Sbjct: 264 SGLDQQNG--QRYNRCGIAKYWCITTPGRLINS--TMPGGGYANKSGTSMAAPHATGALA 319 Query: 357 VLMERYPDLDNQAIRTILLTTSTHLGGGAVDVPNAMFGWGLPDLKKALNGPAQLLGVFNA 416 ++M+RYP L+N+ +LLTT+T L G P GWG+PDL +A++GP QLLG F A Sbjct: 320 LVMQRYPYLNNEQALQVLLTTATQLDGTPTGAPTDTVGWGVPDLGRAMHGPGQLLGRFEA 379 Query: 417 NIGSGRSDTWSNDISEAALVQRKSEEKAQLAAWQ 450 N+ +G D WSN IS++AL+QR++E+ A+ AAWQ Sbjct: 380 NLPAGLRDEWSNPISDSALLQRQAEDAAEHAAWQ 413 >NMA0478_1 [O] COG1404 Subtilisin-like serine proteases NmA Neisseria meningitidis Z2491 Length = 604 Score = 121 bits (304), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 126/417 (30%), Positives = 196/417 (47%), Gaps = 64/417 (15%) Query: 74 MNAQYAYAAGFSGLGIKLGSVDSGLL---LTHAEFVSRNVKALAVIGTYANDGSQYQNGS 130 +N + A AG++G G+++G VD+G ++ E R K Y N + Y Sbjct: 117 INLKPAIEAGYTGRGVEVGIVDTGESVGSISFPELYGR--KEHGYNENYKN-YTAYMRKE 173 Query: 131 QPWKAGD------AFSTTGAVST----LNDKHG---------SHVSGSIAAAKNGAGIMG 171 P + GD +F + T + +H SH+ G + AG G Sbjct: 174 AP-EDGDGKDIEASFDDEAVIETEAKPTDIRHVKEIGHIDVVSHIIGGRSVDGRPAG--G 230 Query: 172 VAFASDYYITNT-NGTDSSVYGVNMDYNYFKAAYGNLASAGVRVINSSWGSPDSR----D 226 +A + +I NT +GT + + + + A+ L GVR++N+S+G+ SR D Sbjct: 231 IAPDATLHIMNTHDGTKNEIMSAAI-----RNAWVKLGERGVRIVNNSFGTT-SRAGTAD 284 Query: 227 DFGSIGGVAAAYQR----LQGGAKKSW---LDAAADVAQAS------NTLMVWAAGNSSK 273 F I Y++ GG K L +D S N L +++A N ++ Sbjct: 285 HF-QIANSEEQYRQALLAYSGGDKTDEGIRLMQQSDYGNLSYHIRNKNMLFIFSASNDAQ 343 Query: 274 SNVNIRSALPYFRPELEQNWIAVAAVNASSVLPSFSNQCGLAKYWCLSAPGSAIPSLNIT 333 + N + LP++ + ++ I VA V+ S + SN CG+ WCLSAP A S+ T Sbjct: 344 AQPNTLTLLPFYEKDAQKGIITVAGVDRSGEKFNGSNHCGITAMWCLSAPYEA--SVRFT 401 Query: 334 SDTALVNASGTSMAAPHVTGALGVLMERYPDLDNQAIRTILLTTSTHLGGGAVDVPNAMF 393 T + +GTS +AP VTG +L+++YP + N +RT LLTT+ +G VD + F Sbjct: 402 R-TNPIQIAGTSFSAPIVTGTAALLLQKYPWMSNDNLRTTLLTTAQDIGAVGVD---SKF 457 Query: 394 GWGLPDLKKALNGPAQL-LGVFNANIGSGRSD---TWSNDISEAALVQRKSEEKAQL 446 GWGL D KA+NGPA G F A+ G SD ++ NDIS + +K + QL Sbjct: 458 GWGLLDTGKAMNGPASFPFGDFTADT-KGTSDIAYSFRNDISGTGGLIKKGGSQLQL 513 Score = 37.0 bits (84), Expect = 0.31, Method: Compositional matrix adjust. Identities = 17/39 (43%), Positives = 24/39 (61%) Query: 570 KTDADYVGTLVKSGAGVLTLSGNNSYSGGTRLEGGTLAV 608 + D G L+K G L L GNN+Y+G T +EGG+L + Sbjct: 494 RNDISGTGGLIKKGGSQLQLHGNNTYTGKTVIEGGSLVL 532 >XF0267_1 [O] COG1404 Subtilisin-like serine proteases Xfa Xylella fastidiosa 9a5c Length = 471 Score = 117 bits (292), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 119/408 (29%), Positives = 181/408 (44%), Gaps = 83/408 (20%) Query: 71 LGAMNAQYAYAAGFSGLGIKLGSVDSGLLLTHAEFVSRNVKALAVIGTYANDGSQYQNGS 130 L N + A+ GF+G G +G VDSG V+RN L + N YQ+ + Sbjct: 16 LDGTNTEPAHTLGFTGKGYMIGVVDSG--------VNRNHVTLHDKVVHNNVYVDYQDPA 67 Query: 131 QPWKAGDAFSTTGAVSTLNDKHGSHVSGSIAAAKNGAGIMGVA-----FASDYYITNTNG 185 P D S HG++V+ IA G+A F++ + + Sbjct: 68 SP----DDVS----------GHGTNVAQLIAGQPVEYWPGGIAPGATIFSARVFSSAAEN 113 Query: 186 TDSSVYGVNM---DYNYFKAAYGNLASAGVRVINSSWGSPDSRDDFGSIGGVAAAYQRLQ 242 G N + K ++ +AGVR+ N+SWG Y+ Sbjct: 114 AKQGPIGGNFFEGEAAQLKRVNADMIAAGVRIQNNSWG-----------------YENQN 156 Query: 243 GGAKKSWLDAAA---------DVAQASNTLMVWAAGNSSKSNVNIRSALPYFRP------ 287 G K+ W+D A D +N L+++A+GN S+ S LP Sbjct: 157 TGDKQVWIDPAVTDAFVNVYRDFVLNNNGLVIFASGNYSQQQPGRLSRLPSLPTVEGGAS 216 Query: 288 --ELEQNWIAVAAVNA---SSVLPSFSNQCGLAKYWCLSAPGSAIP-SLNITS-----DT 336 +LE+ W+ VAA+++ L S+SN CG+A ++CL+APG I N+T+ D Sbjct: 217 PADLERGWLVVAALDSFDHPDQLTSYSNHCGIAMHYCLAAPGDLIEIDPNVTTSPVDGDK 276 Query: 337 ALVNA----SGTSMAAPHVTGALGVLMERYPDLDNQAIRTILLTTSTHLGGGAVDVPNAM 392 +N +GTS AAP V+GA ++ E +P N +R LL T+T LG VD + Sbjct: 277 GYLNGYLIQNGTSFAAPLVSGAAALVWEAFPYFSNDLVRQTLLGTATDLGAPGVD---EV 333 Query: 393 FGWGLPDLKKALNGPAQL-LGVFNANIGSGRSDTWSNDIS-EAALVQR 438 FG+G ++ KA+ GPA+ G + RS TW NDI+ L++R Sbjct: 334 FGYGALNVGKAVLGPAKFDWGDVQVSFDDRRS-TWGNDITGSGGLIKR 380 Score = 39.3 bits (90), Expect = 0.065, Method: Compositional matrix adjust. Identities = 29/74 (39%), Positives = 39/74 (52%), Gaps = 14/74 (18%) Query: 577 GTLVKSGAGVLTLSG-NNSYSGGTRLEGGTLAVAS-----------ATALGSGALG--MN 622 G L+K G G L L G NN Y+G T++ GGTL +S AT +GSG G ++ Sbjct: 375 GGLIKRGTGTLVLGGSNNQYTGATQVLGGTLQASSLGASAVSVSNAATLIGSGRFGGAVS 434 Query: 623 DGTTLRAAADGLAL 636 + TL DGL + Sbjct: 435 NAGTLELGKDGLKV 448 >NMB1969_1 [O] COG1404 Subtilisin-like serine proteases Nme Neisseria meningitidis MC58 Length = 618 Score = 116 bits (291), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 125/428 (29%), Positives = 190/428 (44%), Gaps = 72/428 (16%) Query: 74 MNAQYAYAAGFSGLGIKLGSVDSGLL---LTHAEFVSRNVKALAVIGTYANDGSQYQNGS 130 +N + A AG++G G+++G VD+G ++ E R K Y N + Y Sbjct: 117 INLKPAIEAGYTGRGVEVGIVDTGESVGSISFPELYGR--KEHGYNENYKN-YTAYMRKE 173 Query: 131 QPWKAGD-----AFSTTGAVST----LNDKHG---------SHVSGSIAAAKNGAGIMGV 172 P G +F + T + +H SH+ G + AG G+ Sbjct: 174 APEDGGGKDIEASFDDEAVIETEAKPTDIRHVKEIGHIDLVSHIIGGRSVDGRPAG--GI 231 Query: 173 AFASDYYITNTNGTDSSVYGVNMDYNYFKAAYGNLASAGVRVINSSWGSPDSRD---DFG 229 A + +I NTN + M + A+ L GVR++N+S+G+ SR D Sbjct: 232 APDATLHIMNTNDETKN----EMMVAAIRNAWVKLGERGVRIVNNSFGTT-SRAGTADLF 286 Query: 230 SIGGVAAAYQR----LQGGAKKSW---LDAAADVAQAS------NTLMVWAAGNSSKSNV 276 I Y++ GG K L +D S N L +++ GN +++ Sbjct: 287 QIANSEEQYRQALLDYSGGDKTDEGIRLMQQSDYGNLSYHIRNKNMLFIFSTGNDAQAQP 346 Query: 277 NIRSALPYFRPELEQNWIAVAAVNAS--------------SVLPSFSNQCGLAKYWCLSA 322 N + LP++ + ++ I VA V+ S L SN CG+ WCLSA Sbjct: 347 NTYALLPFYEKDAQKGIITVAGVDRSGEKFKREMYGEPGTEPLEYGSNHCGITAMWCLSA 406 Query: 323 PGSAIPSLNITSDTALVNASGTSMAAPHVTGALGVLMERYPDLDNQAIRTILLTTSTHLG 382 P A S+ T T + +GTS +AP VTG +L+++YP + N +RT LLTT+ +G Sbjct: 407 PYEA--SVRFTR-TNPIQIAGTSFSAPIVTGTAALLLQKYPWMSNDNLRTTLLTTAQDIG 463 Query: 383 GGAVDVPNAMFGWGLPDLKKALNGPAQL-LGVFNANIGSGRSD---TWSNDISEAALVQR 438 VD + FGWGL D KA+NGPA G F A+ G SD ++ NDIS + + Sbjct: 464 AVGVD---SKFGWGLLDAGKAMNGPASFPFGDFTADT-KGTSDIAYSFRNDISGTGGLIK 519 Query: 439 KSEEKAQL 446 K + QL Sbjct: 520 KGGSQLQL 527 Score = 37.0 bits (84), Expect = 0.34, Method: Compositional matrix adjust. Identities = 17/39 (43%), Positives = 24/39 (61%) Query: 570 KTDADYVGTLVKSGAGVLTLSGNNSYSGGTRLEGGTLAV 608 + D G L+K G L L GNN+Y+G T +EGG+L + Sbjct: 508 RNDISGTGGLIKKGGSQLQLHGNNTYTGKTIIEGGSLVL 546 >XF1026_1 [O] COG1404 Subtilisin-like serine proteases Xfa Xylella fastidiosa 9a5c Length = 466 Score = 107 bits (267), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 115/395 (29%), Positives = 185/395 (46%), Gaps = 62/395 (15%) Query: 71 LGAMNAQYAYAAGFSGLGIKLGSVDSGLLLTHAEFVSRNVKALAVIGTYANDGSQYQNGS 130 L N + A GF+G G +G VDSG V+RN L + N YQ+ Sbjct: 16 LDGTNTEPARTLGFTGKGYMIGVVDSG--------VNRNHVTLHNQVIHNNVYVDYQD-- 65 Query: 131 QPWKAGDAFSTTGAVSTLNDKHGSHVSGSIAAAKNGAGIMGVAFASDYYITN--TNGTDS 188 P + D HG++V+ IA G+A + + ++ +S Sbjct: 66 -PASSDDV-----------SGHGTNVAQLIAGQPVEYWPGGIAPGATIFSARVFSSAAES 113 Query: 189 SVYGVNMDYNYF-------KAAYGNLASAGVRVINSSWGSPDSRDDFGSIGGVAAAYQRL 241 + G ++ N+F K ++ +AGVR+ N+SWG +S D GG + Sbjct: 114 AKEG-SISGNFFERETAQLKRVNADMIAAGVRIQNNSWGY-ESED----TGGEPVWRSPI 167 Query: 242 QGGAKKSWLDAAADVAQASNTLMVWAAGNSSKSNVNIRSALPYFRP--------ELEQNW 293 G +++A D +N L+V+A+GN ++ + LP +LE+ W Sbjct: 168 TTGL---FVNAYRDFVLNNNGLVVFASGNEAQPQPGQLARLPSLPTVEGGASPADLERGW 224 Query: 294 IAVAAVNA---SSVLPSFSNQCGLAKYWCLSAPGSAIPSLNITSDTALVNAS-----GTS 345 + VAA+++ L S+SN CG+A ++CL+APG + N ++++ V+ GTS Sbjct: 225 LVVAALDSFDHPDQLTSYSNHCGIAMHYCLAAPGDVVVIHNSVTNSSSVDDEYYELQGTS 284 Query: 346 MAAPHVTGALGVLMERYPDLDNQAIRTILLTTSTHLGGGAVDVPNAMFGWGLPDLKKALN 405 AAP V+GA ++ E +P N +R LL T+T LG VD +FG+G ++ KA+ Sbjct: 285 FAAPLVSGAAALVWEAFPYFSNDLVRQTLLGTATDLGVPGVD---EVFGYGALNVGKAVL 341 Query: 406 GPAQL-LGVFNANIGSGRSDTWSNDIS-EAALVQR 438 GPA+ G + RS TW NDI+ L++R Sbjct: 342 GPAKFDWGDVQVSFDDRRS-TWGNDITGSGGLIKR 375 Score = 39.7 bits (91), Expect = 0.042, Method: Compositional matrix adjust. Identities = 29/74 (39%), Positives = 39/74 (52%), Gaps = 14/74 (18%) Query: 577 GTLVKSGAGVLTLSG-NNSYSGGTRLEGGTLAVAS-----------ATALGSGALG--MN 622 G L+K G G L L G NN Y+G T++ GGTL +S AT +GSG G ++ Sbjct: 370 GGLIKRGTGTLVLGGSNNQYTGATQVLGGTLQASSLGVSAVSVANAATLIGSGRFGGALS 429 Query: 623 DGTTLRAAADGLAL 636 + TL DGL + Sbjct: 430 NAGTLELGKDGLKV 443