BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.3117.p (455 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_ycbE [GEPR] COG0477 Permeases of the major facilitator superf... 607 e-173 RSp0828 [GEPR] COG0477 Permeases of the major facilitator superf... 599 e-171 ygcZ [GEPR] COG0477 Permeases of the major facilitator superfami... 591 e-168 Z4105 [GEPR] COG0477 Permeases of the major facilitator superfam... 590 e-168 ECs3649 [GEPR] COG0477 Permeases of the major facilitator superf... 590 e-168 >BS_ycbE [GEPR] COG0477 Permeases of the major facilitator superfamily Bsu Bacillus subtilis Length = 455 Score = 607 bits (1564), Expect = e-173, Method: Compositional matrix adjust. Identities = 285/443 (64%), Positives = 354/443 (79%) Query: 12 QSNIPSGAGAVKPTHIRYLILFLLFVVTTVNYADRATLSIAGSAMKTELSLDPVTMGYIF 71 + + S A K T +R+ I+F+LF+VT++NYADRATLSI G +++ +L LD V MGY+F Sbjct: 2 KKDFASVTPAGKKTSVRWFIVFMLFLVTSINYADRATLSITGDSVQHDLGLDSVAMGYVF 61 Query: 72 SAFSWAYVLAQLPGGWLLDRFGSKTIYMWSIALWSFFTFLQAGVTWMSTGAAVVALFLLR 131 SAF WAYV+ QLPGGWLLDRFGSKTI SI WSFFT LQ + + S G A++ LF LR Sbjct: 62 SAFGWAYVIGQLPGGWLLDRFGSKTIIALSIFFWSFFTLLQGAIGFFSAGTAIILLFALR 121 Query: 132 FMVGLAEAPSFPANGRIVAAWYPTKERGTASAIFNSAQYFAAVIFTPLMAWIVHSYSWHH 191 F+VGL+EAPSFP NGR+VA+W+P+ ERGTASA FNSAQYFA VIF PLM W+ HS+ WH Sbjct: 122 FLVGLSEAPSFPGNGRVVASWFPSSERGTASAFFNSAQYFAIVIFPPLMGWLTHSFGWHS 181 Query: 192 VFTVMGVVGILLALIWGRIIYSPKDHPRINAAELHHIESGGGLVDMDNKKVAAPSVQGKG 251 VF VMG+ GILLA+IW + +Y PK HP++N AEL +IE GGGL+ MD+ K + Sbjct: 182 VFVVMGIAGILLAVIWLKTVYEPKKHPKVNEAELAYIEQGGGLISMDDSKSKQETESKWP 241 Query: 252 YLRQLLSNRMLLGVYIGQYCINVITYFFLTWFPVYLVQERGMSILKAGFVASIPAVCGFI 311 Y++QLL+NRML+GVYI QYCI +TYFFLTWFPVYLVQ RGMSIL+AGFVAS+PA+CGF Sbjct: 242 YIKQLLTNRMLIGVYIAQYCITTLTYFFLTWFPVYLVQARGMSILEAGFVASLPALCGFA 301 Query: 312 GGVVGGLISDRLIKSGLSVTWSRKIPIVGGMLLSMTMILCNYVQAQWLVVGIMALAFFGK 371 GGV+GG++SD L+K G S+T++RK+PI+ GMLLS +MI+CNY + WLVV IM+LAFFGK Sbjct: 302 GGVLGGIVSDILLKKGRSLTFARKVPIIAGMLLSCSMIVCNYTDSAWLVVVIMSLAFFGK 361 Query: 372 GVGALGWAVVADTAPKQIVGLSGGLFNMFGNVAGITTPIVIGYIVKETGSFSGALVFVGI 431 G GALGWAVV+DT+PK+ GLSGGLFN FGN+A ITTPI+IGYIV TGSF+GALVFVG Sbjct: 362 GFGALGWAVVSDTSPKECAGLSGGLFNTFGNIASITTPIIIGYIVNATGSFNGALVFVGA 421 Query: 432 NALVTVISYLVIVKEIKRVELKD 454 NA+ ++SYL++V IKRV LK Sbjct: 422 NAIAAILSYLLLVGPIKRVVLKK 444 >RSp0828 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 450 Score = 599 bits (1544), Expect = e-171, Method: Compositional matrix adjust. Identities = 290/431 (67%), Positives = 361/431 (83%) Query: 23 KPTHIRYLILFLLFVVTTVNYADRATLSIAGSAMKTELSLDPVTMGYIFSAFSWAYVLAQ 82 + + +R++IL +LF+VTT+NYADRAT+S+AGSAM+ +L +D V++GYIFSAF WAYV+AQ Sbjct: 18 RTSRVRFMILAMLFIVTTINYADRATISMAGSAMQKDLGIDAVSLGYIFSAFGWAYVIAQ 77 Query: 83 LPGGWLLDRFGSKTIYMWSIALWSFFTFLQAGVTWMSTGAAVVALFLLRFMVGLAEAPSF 142 +PGGWLLDRFGS+ +Y +SI LWS FT +Q + + + AA+V +F LRFMVG+AEAPSF Sbjct: 78 IPGGWLLDRFGSRRVYSFSILLWSLFTLMQGTIGFFTGMAAIVLVFFLRFMVGVAEAPSF 137 Query: 143 PANGRIVAAWYPTKERGTASAIFNSAQYFAAVIFTPLMAWIVHSYSWHHVFTVMGVVGIL 202 PAN RIVAAW+P ERGTASAIFNSAQY A VIF PLMAW+VH++ WH+VF VMGV+GI+ Sbjct: 138 PANSRIVAAWFPANERGTASAIFNSAQYAATVIFAPLMAWLVHAFGWHYVFIVMGVIGIV 197 Query: 203 LALIWGRIIYSPKDHPRINAAELHHIESGGGLVDMDNKKVAAPSVQGKGYLRQLLSNRML 262 +AL W R ++ PKDHPRI AE+ +IE+GGGLV+MD VA GY++QLL NRML Sbjct: 198 MALAWKRFMHDPKDHPRITRAEIEYIEAGGGLVNMDRAGVAKTEGPDMGYIKQLLRNRML 257 Query: 263 LGVYIGQYCINVITYFFLTWFPVYLVQERGMSILKAGFVASIPAVCGFIGGVVGGLISDR 322 +GVYI QYCIN +TYFF+TWFPVYLVQ RGMSILKAGFVASIPAVCGF+GG++GGL+SD Sbjct: 258 MGVYIAQYCINALTYFFITWFPVYLVQARGMSILKAGFVASIPAVCGFLGGILGGLVSDA 317 Query: 323 LIKSGLSVTWSRKIPIVGGMLLSMTMILCNYVQAQWLVVGIMALAFFGKGVGALGWAVVA 382 L++ G S++ +RK+PIV GMLLSM+M++CNYV AQ +VV +MAL+FFGKG+GALGWAV + Sbjct: 318 LLRRGASLSVARKVPIVLGMLLSMSMVICNYVDAQGIVVALMALSFFGKGLGALGWAVNS 377 Query: 383 DTAPKQIVGLSGGLFNMFGNVAGITTPIVIGYIVKETGSFSGALVFVGINALVTVISYLV 442 DTAPKQI GLSG L N FGN++ ITTPI IGYIV TGSF+GALV+VGI+ALV + YLV Sbjct: 378 DTAPKQIAGLSGALMNTFGNLSSITTPIAIGYIVNTTGSFNGALVYVGIHALVACLCYLV 437 Query: 443 IVKEIKRVELK 453 +V EIKRVELK Sbjct: 438 MVGEIKRVELK 448 >ygcZ [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 450 Score = 591 bits (1523), Expect = e-168, Method: Compositional matrix adjust. Identities = 284/444 (63%), Positives = 352/444 (79%), Gaps = 3/444 (0%) Query: 13 SNIPSGAGAV-KPTHIRYLILFLLFVVTTVNYADRATLSIAGSAMKTELSLDPVTMGYIF 71 S++ A +V K T+ RY I+ +LF+VT+ NY DRATLSIAGS M ++ LDPV MGY+F Sbjct: 2 SSLSQAASSVEKRTNARYWIVVMLFIVTSFNYGDRATLSIAGSEMAKDIGLDPVGMGYVF 61 Query: 72 SAFSWAYVLAQLPGGWLLDRFGSKTIYMWSIALWSFFTFLQAGVTWMSTGAAVVALFLLR 131 SAFSWAYV+ Q+PGGWLLDRFGSK +Y WSI +WS FT LQ V S +VALF LR Sbjct: 62 SAFSWAYVIGQIPGGWLLDRFGSKRVYFWSIFIWSMFTLLQGFVDIFSGFGIIVALFTLR 121 Query: 132 FMVGLAEAPSFPANGRIVAAWYPTKERGTASAIFNSAQYFAAVIFTPLMAWIVHSYSWHH 191 F+VGLAEAPSFP N RIVAAW+P +ERGTA +IFNSAQYFA VIF P+M W+ H W H Sbjct: 122 FLVGLAEAPSFPGNSRIVAAWFPAQERGTAVSIFNSAQYFATVIFAPIMGWLTHEVGWSH 181 Query: 192 VFTVMGVVGILLALIWGRIIYSPKDHPRINAAELHHIESGGGLVDMD--NKKVAAPSVQG 249 VF MG +GI+++ IW ++I+ P HP +N EL +I +GG L++MD N KV P Sbjct: 182 VFFFMGGLGIVISFIWLKVIHEPNQHPGVNKKELEYIAAGGALINMDQQNTKVKVPFSVK 241 Query: 250 KGYLRQLLSNRMLLGVYIGQYCINVITYFFLTWFPVYLVQERGMSILKAGFVASIPAVCG 309 G ++QLL +RM++GVYIGQYCIN +TYFF+TWFPVYLVQ RGMSILKAGFVAS+PAVCG Sbjct: 242 WGQIKQLLGSRMMIGVYIGQYCINALTYFFITWFPVYLVQARGMSILKAGFVASVPAVCG 301 Query: 310 FIGGVVGGLISDRLIKSGLSVTWSRKIPIVGGMLLSMTMILCNYVQAQWLVVGIMALAFF 369 FIGGV+GG+ISD L++ S+ +RK PIV GMLLSM M+ CNYV +W+++G MALAFF Sbjct: 302 FIGGVLGGIISDWLMRRTGSLNIARKTPIVMGMLLSMVMVFCNYVNVEWMIIGFMALAFF 361 Query: 370 GKGVGALGWAVVADTAPKQIVGLSGGLFNMFGNVAGITTPIVIGYIVKETGSFSGALVFV 429 GKG+GALGWAV+ADTAPK+I GLSGGLFNMFGN++GI TPI IGYIV TGSF+GAL++V Sbjct: 362 GKGIGALGWAVMADTAPKEISGLSGGLFNMFGNISGIVTPIAIGYIVGTTGSFNGALIYV 421 Query: 430 GINALVTVISYLVIVKEIKRVELK 453 G++AL+ V+SYLV+V +IKR+ELK Sbjct: 422 GVHALIAVLSYLVLVGDIKRIELK 445 >Z4105 [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 450 Score = 590 bits (1521), Expect = e-168, Method: Compositional matrix adjust. Identities = 284/444 (63%), Positives = 351/444 (79%), Gaps = 3/444 (0%) Query: 13 SNIPSGAGAV-KPTHIRYLILFLLFVVTTVNYADRATLSIAGSAMKTELSLDPVTMGYIF 71 S++ A +V K T+ RY I+ +LF+VT+ NY DRATLSIAGS M ++ LDPV MGY+F Sbjct: 2 SSLSQAASSVEKRTNARYWIVVMLFIVTSFNYGDRATLSIAGSEMAKDIGLDPVGMGYVF 61 Query: 72 SAFSWAYVLAQLPGGWLLDRFGSKTIYMWSIALWSFFTFLQAGVTWMSTGAAVVALFLLR 131 SAFSWAYV+ Q+PGGWLLDRFGSK +Y WSI +WS FT LQ V S +VALF LR Sbjct: 62 SAFSWAYVIGQIPGGWLLDRFGSKRVYFWSIFIWSMFTLLQGFVDIFSGFGIIVALFTLR 121 Query: 132 FMVGLAEAPSFPANGRIVAAWYPTKERGTASAIFNSAQYFAAVIFTPLMAWIVHSYSWHH 191 F+VGLAEAPSFP N RIVAAW+P +ERGTA +IFNSAQYFA VIF P+M W+ H W H Sbjct: 122 FLVGLAEAPSFPGNSRIVAAWFPAQERGTAVSIFNSAQYFATVIFAPIMGWLTHEVGWSH 181 Query: 192 VFTVMGVVGILLALIWGRIIYSPKDHPRINAAELHHIESGGGLVDMD--NKKVAAPSVQG 249 VF MG +GI ++ IW ++I+ P HP +N EL +I +GG L++MD N KV P Sbjct: 182 VFFFMGGLGIAISFIWLKVIHEPNQHPGVNQKELEYIAAGGALINMDQQNTKVKVPFSVK 241 Query: 250 KGYLRQLLSNRMLLGVYIGQYCINVITYFFLTWFPVYLVQERGMSILKAGFVASIPAVCG 309 G ++QLL +RM++GVYIGQYCIN +TYFF+TWFPVYLVQ RGMSILKAGFVAS+PAVCG Sbjct: 242 WGQIKQLLGSRMMIGVYIGQYCINALTYFFITWFPVYLVQARGMSILKAGFVASVPAVCG 301 Query: 310 FIGGVVGGLISDRLIKSGLSVTWSRKIPIVGGMLLSMTMILCNYVQAQWLVVGIMALAFF 369 FIGGV+GG+ISD L++ S+ +RK PIV GMLLSM M+ CNYV +W+++G MALAFF Sbjct: 302 FIGGVLGGIISDWLMRRTGSLNIARKTPIVMGMLLSMVMVFCNYVNVEWMIIGFMALAFF 361 Query: 370 GKGVGALGWAVVADTAPKQIVGLSGGLFNMFGNVAGITTPIVIGYIVKETGSFSGALVFV 429 GKG+GALGWAV+ADTAPK+I GLSGGLFNMFGN++GI TPI IGYIV TGSF+GAL++V Sbjct: 362 GKGIGALGWAVMADTAPKEISGLSGGLFNMFGNISGIVTPIAIGYIVGTTGSFNGALIYV 421 Query: 430 GINALVTVISYLVIVKEIKRVELK 453 G++AL+ V+SYLV+V +IKR+ELK Sbjct: 422 GVHALIAVLSYLVLVGDIKRIELK 445 >ECs3649 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 450 Score = 590 bits (1521), Expect = e-168, Method: Compositional matrix adjust. Identities = 284/444 (63%), Positives = 351/444 (79%), Gaps = 3/444 (0%) Query: 13 SNIPSGAGAV-KPTHIRYLILFLLFVVTTVNYADRATLSIAGSAMKTELSLDPVTMGYIF 71 S++ A +V K T+ RY I+ +LF+VT+ NY DRATLSIAGS M ++ LDPV MGY+F Sbjct: 2 SSLSQAASSVEKRTNARYWIVVMLFIVTSFNYGDRATLSIAGSEMAKDIGLDPVGMGYVF 61 Query: 72 SAFSWAYVLAQLPGGWLLDRFGSKTIYMWSIALWSFFTFLQAGVTWMSTGAAVVALFLLR 131 SAFSWAYV+ Q+PGGWLLDRFGSK +Y WSI +WS FT LQ V S +VALF LR Sbjct: 62 SAFSWAYVIGQIPGGWLLDRFGSKRVYFWSIFIWSMFTLLQGFVDIFSGFGIIVALFTLR 121 Query: 132 FMVGLAEAPSFPANGRIVAAWYPTKERGTASAIFNSAQYFAAVIFTPLMAWIVHSYSWHH 191 F+VGLAEAPSFP N RIVAAW+P +ERGTA +IFNSAQYFA VIF P+M W+ H W H Sbjct: 122 FLVGLAEAPSFPGNSRIVAAWFPAQERGTAVSIFNSAQYFATVIFAPIMGWLTHEVGWSH 181 Query: 192 VFTVMGVVGILLALIWGRIIYSPKDHPRINAAELHHIESGGGLVDMD--NKKVAAPSVQG 249 VF MG +GI ++ IW ++I+ P HP +N EL +I +GG L++MD N KV P Sbjct: 182 VFFFMGGLGIAISFIWLKVIHEPNQHPGVNQKELEYIAAGGALINMDQQNTKVKVPFSVK 241 Query: 250 KGYLRQLLSNRMLLGVYIGQYCINVITYFFLTWFPVYLVQERGMSILKAGFVASIPAVCG 309 G ++QLL +RM++GVYIGQYCIN +TYFF+TWFPVYLVQ RGMSILKAGFVAS+PAVCG Sbjct: 242 WGQIKQLLGSRMMIGVYIGQYCINALTYFFITWFPVYLVQARGMSILKAGFVASVPAVCG 301 Query: 310 FIGGVVGGLISDRLIKSGLSVTWSRKIPIVGGMLLSMTMILCNYVQAQWLVVGIMALAFF 369 FIGGV+GG+ISD L++ S+ +RK PIV GMLLSM M+ CNYV +W+++G MALAFF Sbjct: 302 FIGGVLGGIISDWLMRRTGSLNIARKTPIVMGMLLSMVMVFCNYVNVEWMIIGFMALAFF 361 Query: 370 GKGVGALGWAVVADTAPKQIVGLSGGLFNMFGNVAGITTPIVIGYIVKETGSFSGALVFV 429 GKG+GALGWAV+ADTAPK+I GLSGGLFNMFGN++GI TPI IGYIV TGSF+GAL++V Sbjct: 362 GKGIGALGWAVMADTAPKEISGLSGGLFNMFGNISGIVTPIAIGYIVGTTGSFNGALIYV 421 Query: 430 GINALVTVISYLVIVKEIKRVELK 453 G++AL+ V+SYLV+V +IKR+ELK Sbjct: 422 GVHALIAVLSYLVLVGDIKRIELK 445