BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.3086.p (427 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA4343 [GEPR] COG0477 Permeases of the major facilitator superfa... 338 2e-92 RSc3059 [GEPR] COG0477 Permeases of the major facilitator superf... 307 3e-83 RSp0536 [GEPR] COG0477 Permeases of the major facilitator superf... 302 8e-82 RSc3060 [GEPR] COG0477 Permeases of the major facilitator superf... 295 2e-79 PA5476 [GEPR] COG0477 Permeases of the major facilitator superfa... 289 8e-78 >PA4343 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 439 Score = 338 bits (866), Expect = 2e-92, Method: Compositional matrix adjust. Identities = 181/407 (44%), Positives = 267/407 (65%), Gaps = 4/407 (0%) Query: 19 RAIISSSIGNALEWFDILIYGAFAVVIAKQFFPTGDDSVSLLLTFATFGVSFFMRPLGAV 78 R + ++ IGNALEW+D ++YG + +IA+ FFP+GD+ SLL+ ATFGV FFMRP+G V Sbjct: 12 RQVAAAVIGNALEWYDFIVYGFLSSLIARLFFPSGDEYTSLLMALATFGVGFFMRPVGGV 71 Query: 79 VLGAYSDRAGRKAALMLSITLMTIGTAMIAFMPSYASIGLLAPAGIALGKMIQGFSAGGE 138 +LG Y+DR GRKAA+ L I LMT+ AMIAF P+YA+IG+ AP I + +M+QGF+ GGE Sbjct: 72 LLGLYADRRGRKAAMQLIILLMTLSIAMIAFAPTYAAIGVGAPLLIVIARMLQGFATGGE 131 Query: 139 FGSSTAFLVEHA-PHRRGFFSSWQVASQGISLLLAAVFGAVLNNLLTPEQLASWGWRVPF 197 + S+TAFLVE A PHRRG + SWQ+ Q +++ A GA++ + L E L SWGWRVPF Sbjct: 132 YASATAFLVESAPPHRRGLYGSWQLFGQCLAVFAGAGMGALVTHCLDAEALESWGWRVPF 191 Query: 198 IFGLLIAPAGIYIRRNLEEAPEFEQASEK--TKAPLRDTFAHQKMRLLIGAGSVIMATVS 255 +FGLLI P G++IRR + E F +A + + L + +L+ G ++ TVS Sbjct: 192 LFGLLIGPVGLWIRRYMGETEAFLEAIREPGERQGLLGVLREYRRSVLVSMGLTVVGTVS 251 Query: 256 VYLSLY-IPTYAVKQLGLPAWSSFAAMSVAGLIMFIGSPLVGALSDKIGRTPFMIASSAL 314 Y+ L +PT+A KQLGLP F A +M + PL G LSD++GR P ++ ++ Sbjct: 252 FYVVLVNMPTFAHKQLGLPLDEVFMVQMAAVALMTLVIPLAGGLSDRVGRRPVLLVATLA 311 Query: 315 YIVLTYPMFVFLTNSPGFLQLLLLQTVIGVLMTMYFAAMPALLADIFPVATRGTGMSLAY 374 ++++ YP+F ++ +P +LLL+Q ++ + +F P +A+ FPV R TG+++AY Sbjct: 312 FMLMVYPLFAWVAAAPSLGRLLLMQLLLCTAIGGFFGPAPTAVAEQFPVRVRSTGLAVAY 371 Query: 375 NIAVTLFGGFAGLIITWLIDVTGDKLSVSYFVIFGAVLSLAASTAAR 421 N+AV LFGGFA I+TWL +V G ++ +++V+ A L L A+ R Sbjct: 372 NLAVMLFGGFAPFIVTWLTEVGGSPVAPAFYVLGAAFLGLLATLYLR 418 >RSc3059 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 431 Score = 307 bits (786), Expect = 3e-83, Method: Compositional matrix adjust. Identities = 174/405 (42%), Positives = 247/405 (60%), Gaps = 9/405 (2%) Query: 19 RAIISSSIGNALEWFDILIYGAFAVVIAKQFFPTGDDSVSLLLTFATFGVSFFMRPLGAV 78 R+I GN LE +D ++YG +A IA FFP ++ +SL+L+ TFGV F MRPLGA+ Sbjct: 12 RSIFRVVSGNFLEMYDFMVYGYYAKAIADTFFPADNEFLSLMLSLVTFGVGFLMRPLGAL 71 Query: 79 VLGAYSDRAGRKAALMLSITLMTIGTAMIAFMPSYASIGLLAPAGIALGKMIQGFSAGGE 138 +LGAY DR GR+A L+L++ LM GT +IA +P YA+IGL AP + +G+++QGFSAG E Sbjct: 72 ILGAYIDRHGRRAGLILTLGLMACGTLLIALVPGYATIGLAAPLLVLIGRLLQGFSAGVE 131 Query: 139 FGSSTAFLVE-HAPHRRGFFSSWQVASQGISLLLAAVFGAVLNNLLTPEQLASWGWRVPF 197 G + +L E P R+GFF SWQ ASQ ++++ AA+ G +L+ L+P+++ WGWRVPF Sbjct: 132 LGGVSVYLAEISTPGRKGFFVSWQSASQQVAVMFAALLGVLLSFQLSPKEMGEWGWRVPF 191 Query: 198 IFGLLIAPAGIYIRRNLEEAPEFEQASEKTKAPLRDTFAH--QKMRLLIGAGS--VIMAT 253 + G LI P IRR+L+E EF+Q K + L + F + R L+GAG+ V+M T Sbjct: 192 LVGCLIVPFLFLIRRSLQETEEFKQ--RKHRPALGEIFRSMGENWR-LVGAGTLLVVMTT 248 Query: 254 VSVYL-SLYIPTYAVKQLGLPAWSSFAAMSVAGLIMFIGSPLVGALSDKIGRTPFMIASS 312 VS YL + Y PT+ L L S G F P++G++SD+IGR P +I + Sbjct: 249 VSFYLITAYTPTFGKSVLHLSNLDSLIVTLCVGASNFFWLPVMGSVSDRIGRRPLLITFT 308 Query: 313 ALYIVLTYPMFVFLTNSPGFLQLLLLQTVIGVLMTMYFAAMPALLADIFPVATRGTGMSL 372 AL ++ YP +L P F +LL ++ + L Y AM L +I P A R TG SL Sbjct: 309 ALTLLTAYPAMQWLIAEPSFGRLLAVELWLSFLYGSYNGAMVVTLTEIMPPAVRTTGFSL 368 Query: 373 AYNIAVTLFGGFAGLIITWLIDVTGDKLSVSYFVIFGAVLSLAAS 417 AY++A +FGGF I TWLI TG+K ++ F A+ L A+ Sbjct: 369 AYSLATAIFGGFTPAIATWLIHATGNKAMPGLWLSFAAICGLVAT 413 >RSp0536 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 441 Score = 302 bits (774), Expect = 8e-82, Method: Compositional matrix adjust. Identities = 171/407 (42%), Positives = 250/407 (61%), Gaps = 4/407 (0%) Query: 12 TTHPQARRAIISSSIGNALEWFDILIYGAFAVVIAKQFFPTGDDSVSLLLTFATFGVSFF 71 T+ P+ R A+ ++ +GNA EWFD +YG FA VIA FP+ + +LLL ATFGV F Sbjct: 13 TSLPRQRHAVATAILGNAFEWFDFTLYGFFAPVIATVLFPSANPFTALLLAIATFGVGFV 72 Query: 72 MRPLGAVVLGAYSDRAGRKAALMLSITLMTIGTAMIAFMPSYASIGLLAPAGIALGKMIQ 131 RPLG +VLG Y+DR GR+ AL LS LM +GTA+IA P+YA G+ AP + +++Q Sbjct: 73 TRPLGGIVLGIYADRRGRRPALALSALLMALGTALIAIAPTYAQAGIAAPVIAVIARLLQ 132 Query: 132 GFSAGGEFGSSTAFLVEHAPH-RRGFFSSWQVASQGISLLLAAVFGAVLNNLLTPEQLAS 190 GFSAGGE G +TA+L E AP +R F++SW AS G++++ A+ G + +LL E L + Sbjct: 133 GFSAGGEMGGATAYLNEIAPPGKRAFYTSWIQASVGLAIVCGAMLGTLATSLLDAEALRA 192 Query: 191 WGWRVPFIFGLLIAPAGIYIRRNLEEAPEFEQASEKTKA--PLRDTFAHQKMRLLIGAGS 248 WGWR+PF G+LI P G IR L+E P F +A+ + +A PL + + +LIGA Sbjct: 193 WGWRIPFALGVLIGPIGYVIRSRLDETPAFARAATEARADSPLLEVVRRHRRAVLIGASI 252 Query: 249 VIMATVSVYLSL-YIPTYAVKQLGLPAWSSFAAMSVAGLIMFIGSPLVGALSDKIGRTPF 307 VI+ TV Y+ L Y+ TYA+ L LP+ + FA +G+ M + +PL G L+D++G Sbjct: 253 VILWTVCTYVLLFYMQTYAIHVLKLPSSAGFAGSMASGVTMMLTAPLFGWLADRLGYQRV 312 Query: 308 MIASSALYIVLTYPMFVFLTNSPGFLQLLLLQTVIGVLMTMYFAAMPALLADIFPVATRG 367 + ++ +VL YP++ +L ++P L+ +Q V G+L Y +P AD+FP Sbjct: 313 LSGAALAILVLAYPLYAYLNHAPAAGTLIGVQIVFGLLSAAYTGPIPVAFADLFPTKVLS 372 Query: 368 TGMSLAYNIAVTLFGGFAGLIITWLIDVTGDKLSVSYFVIFGAVLSL 414 TG+S AYN+ V L GGFA +TWL L+ +V+ A++SL Sbjct: 373 TGLSTAYNLTVMLIGGFAPFYLTWLSHAFDPMLAPVLYVMVAALVSL 419 >RSc3060 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 433 Score = 295 bits (754), Expect = 2e-79, Method: Compositional matrix adjust. Identities = 172/404 (42%), Positives = 240/404 (59%), Gaps = 7/404 (1%) Query: 19 RAIISSSIGNALEWFDILIYGAFAVVIAKQFFPTGDDSVSLLLTFATFGVSFFMRPLGAV 78 RAI GN LE FD ++YG +A IA FFP G+ +SL+L+ TFG F MRPLGA+ Sbjct: 12 RAIFRVVSGNFLEMFDFMVYGYYATAIAATFFPAGNAFLSLMLSLMTFGAGFLMRPLGAI 71 Query: 79 VLGAYSDRAGRKAALMLSITLMTIGTAMIAFMPSYASIGLLAPAGIALGKMIQGFSAGGE 138 VLGAY DR GR+A L+L++ LM GT +IA +P Y +IGL AP + +G+++QGFSAGGE Sbjct: 72 VLGAYIDRHGRRAGLILTLVLMACGTMLIALVPGYGTIGLAAPLLVLIGRLLQGFSAGGE 131 Query: 139 FGSSTAFLVEHA-PHRRGFFSSWQVASQGISLLLAAVFGAVLNNLLTPEQLASWGWRVPF 197 G + +L E A P R+GF+ SWQ SQ ++++ AA+ G +L+ L+P+++ WGWRVPF Sbjct: 132 PGGVSVYLSEIATPGRKGFYVSWQSGSQQVAVMFAALLGVLLSFKLSPKEMGEWGWRVPF 191 Query: 198 IFGLLIAPAGIYIRRNLEEAPEFEQASEK-TKAPLRDTFAHQKMRLLIGAGSV--IMATV 254 + G LI P +IRR+L E EFEQ + T L + L GAG++ +M TV Sbjct: 192 LIGCLIVPFLFFIRRSLRETEEFEQRKHRPTMGELLRSMGENWR--LAGAGTLLAVMTTV 249 Query: 255 SVYL-SLYIPTYAVKQLGLPAWSSFAAMSVAGLIMFIGSPLVGALSDKIGRTPFMIASSA 313 S YL + Y PT+ L + + S G I P++G+LSD+IGR +I SA Sbjct: 250 SFYLITAYTPTFGRNVLHMSDFDSLIVTLCVGASNLIWLPVMGSLSDRIGRRTPLIVFSA 309 Query: 314 LYIVLTYPMFVFLTNSPGFLQLLLLQTVIGVLMTMYFAAMPALLADIFPVATRGTGMSLA 373 L ++ YP +L P F +LL ++ + L Y AM L +I P R TG SLA Sbjct: 310 LTLLTAYPAMTWLIAEPSFGRLLAVELWLSFLYGGYNGAMIVTLTEIMPPQLRTTGFSLA 369 Query: 374 YNIAVTLFGGFAGLIITWLIDVTGDKLSVSYFVIFGAVLSLAAS 417 Y++A +FGGF I T LI TG+K ++ F A+ L A+ Sbjct: 370 YSLATAIFGGFTPAIATGLIHATGNKAMPGLWLSFAAICGLVAT 413 >PA5476 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 429 Score = 289 bits (740), Expect = 8e-78, Method: Compositional matrix adjust. Identities = 164/383 (42%), Positives = 230/383 (60%), Gaps = 3/383 (0%) Query: 20 AIISSSIGNALEWFDILIYGAFAVVIAKQFFPTGDDSVSLLLTFATFGVSFFMRPLGAVV 79 AI GN LE +D ++YG +A IAK FFP + SL+L+ ATFG F MRPLGAV Sbjct: 10 AIFRVVSGNFLEMYDFMVYGFYATAIAKTFFPGDNPFASLMLSLATFGAGFLMRPLGAVF 69 Query: 80 LGAYSDRAGRKAALMLSITLMTIGTAMIAFMPSYASIGLLAPAGIALGKMIQGFSAGGEF 139 LGAY DR GR+ L++++ LM +GT +IAF+P YA++G+ AP + G+++QGFSAG E Sbjct: 70 LGAYIDRHGRRQGLIITLGLMAMGTLLIAFVPGYATLGVAAPLLVLFGRLLQGFSAGVEL 129 Query: 140 GSSTAFLVEHA-PHRRGFFSSWQVASQGISLLLAAVFGAVLNNLLTPEQLASWGWRVPFI 198 G + +L E A P R+GFF SWQ ASQ ++++ A + G +LN L+P+ + WGWRVPF Sbjct: 130 GGVSVYLSEIATPGRKGFFVSWQSASQQVAVVFAGLLGVLLNQWLSPQDMGEWGWRVPFF 189 Query: 199 FGLLIAPAGIYIRRNLEEAPEFEQASEK-TKAPLRDTFAHQKMRLLIGAGSVIMATVSVY 257 G LI PA IRR+LEE PEFE + + + + + + +L G V+M TVS Y Sbjct: 190 IGCLIVPALFVIRRSLEETPEFEARTHRPSLSQVLRSIGQNFGVVLAGTAMVVMTTVSFY 249 Query: 258 L-SLYIPTYAVKQLGLPAWSSFAAMSVAGLIMFIGSPLVGALSDKIGRTPFMIASSALYI 316 L + Y PT+ +L L S GL FI P++GA SD+IGR P ++ +SAL + Sbjct: 250 LITAYTPTFGKNELQLSDLDSLLVTMCIGLSNFIWLPVMGAFSDRIGRKPLLLGASALAL 309 Query: 317 VLTYPMFVFLTNSPGFLQLLLLQTVIGVLMTMYFAAMPALLADIFPVATRGTGMSLAYNI 376 + YP +L P F LL ++ + L + Y AM L ++ P R TG SLAY++ Sbjct: 310 LTAYPALSWLVREPSFAGLLGVELWLSFLYSSYNGAMVVALTEVMPADVRTTGFSLAYSL 369 Query: 377 AVTLFGGFAGLIITWLIDVTGDK 399 A FGGF + TWLI ++ Sbjct: 370 ATATFGGFTPAVCTWLIHTLDNR 392