BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.3072.p (376 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2416 [R] COG0795 Predicted permeases Rso Ralstonia solanacearum 319 6e-87 NMA1759 [R] COG0795 Predicted permeases NmA Neisseria meningitid... 233 7e-61 NMB1570 [R] COG0795 Predicted permeases Nme Neisseria meningitid... 231 2e-60 PA3828 [R] COG0795 Predicted permeases Pae Pseudomonas aeruginosa 163 7e-40 VC2500 [R] COG0795 Predicted permeases Vch Vibrio cholerae 149 1e-35 >RSc2416 [R] COG0795 Predicted permeases Rso Ralstonia solanacearum Length = 372 Score = 319 bits (818), Expect = 6e-87, Method: Compositional matrix adjust. Identities = 162/337 (48%), Positives = 231/337 (68%), Gaps = 1/337 (0%) Query: 1 MIFQRALRRELTSTAGGVFTTLFTITLTVMLIKILGQAAGGQVASQDVLALIGFQSLNYM 60 MIF++ALRREL+ TAG VF L T LT ++I+ILG AA G+ + DVL LIG +L Y+ Sbjct: 1 MIFEQALRRELSFTAGAVFLVLLTFMLTTLVIRILGMAANGEASPNDVLLLIGLAALGYL 60 Query: 61 PIILILTGFISVLLVMTRSYQDSEIVVWFSCGMSLTRWITPVLRFGWPIMALVAVLSFVV 120 I+L T FISVLLV+TR Y+DSE+VVWF+ G+SLT +I PVLRF P + LV +L+ Sbjct: 61 AILLCATLFISVLLVLTRWYKDSEMVVWFTAGLSLTDFIRPVLRFSLPFVVLVGLLALFG 120 Query: 121 TPWANEQSSEYRSRFEQREDIARVSPGKFQESAAANRIFFVEGISGDASKVRNIFVNTIN 180 PWAN+QS+ +R RFEQR+ ++ +S G+F E A N + F+EG+ RN+FV Sbjct: 121 WPWANQQSALFRDRFEQRDVLSMISAGRFIEPAHGNYVLFIEGVDAGMKHARNLFVANAE 180 Query: 181 QDGKNSVVVAKEGETTVDADGEKFVVMQKGRRYDGSPSLPDFQIVDFERYGLLIGNQSQT 240 QD K V +AK GE +G+++VV+ KGRRY+G+P D++IV+F+RYG+ + N+ Sbjct: 181 QD-KIGVALAKTGEFKAGPNGDRYVVLDKGRRYEGTPGQLDYRIVEFDRYGVKVANKPPQ 239 Query: 241 AAGERSARALQMNELLAKRDGFARGELLWRIALPLMALALMLLAIPLSFVNPRAGRSLGL 300 A ++ ELL+ GEL+WRI LPL+AL +L+AIPL++VNPR GR + Sbjct: 240 ADANLPTKSRPTTELLSNPTPENMGELVWRIGLPLLALNFVLIAIPLAYVNPRLGRYTPM 299 Query: 301 LVALLLFVVYSNTVSVFQASVAQQRMSFVMAWWPVHL 337 + A+L+++ YSN +++ QA VAQ +MS ++AWWP+HL Sbjct: 300 IFAVLIYLTYSNLLNLSQAWVAQGKMSAMLAWWPIHL 336 >NMA1759 [R] COG0795 Predicted permeases NmA Neisseria meningitidis Z2491 Length = 371 Score = 233 bits (593), Expect = 7e-61, Method: Compositional matrix adjust. Identities = 127/374 (33%), Positives = 225/374 (60%), Gaps = 7/374 (1%) Query: 1 MIFQRALRRELTSTAGGVFTTLFTITLTVMLIKILGQAAGGQVASQDVLALIGFQSLNYM 60 MI+QR L +EL+ TA G+F L + ++ I +LG+AA G+VA VLAL+GF + Sbjct: 1 MIYQRNLIKELSFTAVGIFVVLLAVLVSTQAINLLGRAADGRVAIDAVLALVGFWVIGMT 60 Query: 61 PIILILTGFISVLLVMTRSYQDSEIVVWFSCGMSLTRWITPVLRFGWPIMALVAVLSFVV 120 P++L+LT FIS L V+TR ++DSE+ VW SCG++L +WI PV++F P LVAV+ V Sbjct: 61 PLLLVLTAFISTLTVLTRYWRDSEMSVWLSCGLALKQWIRPVMQFAVPFAVLVAVMQLWV 120 Query: 121 TPWANEQSSEYRSRFEQREDIARVSPGKFQESAAAN-RIFFVEGISGDASKVRNIFVNTI 179 PWA +S EY +Q+++++ V G F N R++FVE ++ ++N+F+ Sbjct: 121 IPWAELRSREYAEILKQKQELSLVEAGGFNSLGKRNGRVYFVETFDTESGIMKNLFLREQ 180 Query: 180 NQDGKNSVVVAKEGETTVDADGEKFVVMQKGRRYDGSPSLPDFQIVDFERYGLLIGNQSQ 239 +++G ++++ AKEG +++ D ++ + ++ G RY G+P D+ V F++ L+I + Sbjct: 181 DKNGGDNIIFAKEGNFSLN-DNKRTLELRHGYRYSGTPGRADYNQVSFQKLNLIISTTPK 239 Query: 240 TAAGERSARALQMNELLAKRDGFARGELLWRIALPLMALALMLLAIPLSFVNPRAGRSLG 299 R + +L+ + + EL+WRI+L + L L LLA+PLS+ NPR+G + Sbjct: 240 LIDPVSHRRTIPTAQLIGSSNPQHQAELMWRISLTVSVLLLCLLAVPLSYFNPRSGHTYN 299 Query: 300 LLVALLLFVVYSNTVSVFQASVAQQRMSFVMAWWPVHLIVALLIVGMFALRLNINHPFHP 359 +L+A+ LF++Y N +++ +V ++ F + P+H+I+ ++ + + +R + PF Sbjct: 300 ILIAIGLFLIYQNGLTLLFEAVEDGKIHFWLGLLPMHIIMFVIAIVLLRVRSMPSQPF-- 357 Query: 360 SRLWSRVRRAMTFQ 373 W V +++T + Sbjct: 358 ---WQAVGKSLTLK 368 >NMB1570 [R] COG0795 Predicted permeases Nme Neisseria meningitidis MC58 Length = 371 Score = 231 bits (590), Expect = 2e-60, Method: Compositional matrix adjust. Identities = 127/374 (33%), Positives = 225/374 (60%), Gaps = 7/374 (1%) Query: 1 MIFQRALRRELTSTAGGVFTTLFTITLTVMLIKILGQAAGGQVASQDVLALIGFQSLNYM 60 MI+QR L +EL+ TA G+F L + ++ I +LG+AA G+VA VLAL+GF + Sbjct: 1 MIYQRNLIKELSFTAVGIFVVLLAVLVSTQAINLLGRAADGRVAIDAVLALVGFWVIGMT 60 Query: 61 PIILILTGFISVLLVMTRSYQDSEIVVWFSCGMSLTRWITPVLRFGWPIMALVAVLSFVV 120 P++L+LT FIS L V+TR ++DSE+ VW SCG++L +WI PV++F P LVAV+ V Sbjct: 61 PLLLVLTAFISTLTVLTRYWRDSEMSVWLSCGLALKQWIRPVMQFAVPFAVLVAVMQLWV 120 Query: 121 TPWANEQSSEYRSRFEQREDIARVSPGKFQESAAAN-RIFFVEGISGDASKVRNIFVNTI 179 PWA +S EY +Q+++++ V G+F N R++FVE ++ ++N+F+ Sbjct: 121 IPWAELRSREYAEILKQKQELSLVEAGEFNSLGKRNGRVYFVETFDTESGIMKNLFLREQ 180 Query: 180 NQDGKNSVVVAKEGETTVDADGEKFVVMQKGRRYDGSPSLPDFQIVDFERYGLLIGNQSQ 239 +++G ++++ AKEG +++ D ++ + ++ G RY G+P D+ V F++ L+I + Sbjct: 181 DKNGGDNIIFAKEGNFSLN-DNKRTLELRHGYRYSGTPGRADYNQVSFQKLNLIISTTPK 239 Query: 240 TAAGERSARALQMNELLAKRDGFARGELLWRIALPLMALALMLLAIPLSFVNPRAGRSLG 299 R + +L+ + + EL+WRI+L + L L LLA+PLS+ NPR+G + Sbjct: 240 LIDPVSHRRTIPTAQLIGSSNPQHQAELMWRISLTVSVLLLCLLAVPLSYFNPRSGHTYN 299 Query: 300 LLVALLLFVVYSNTVSVFQASVAQQRMSFVMAWWPVHLIVALLIVGMFALRLNINHPFHP 359 +L+A+ LF++Y N +++ +V ++ F + P+H+I+ + + + +R + PF Sbjct: 300 ILIAIGLFLIYQNGLTLLFEAVEDGKIHFWLGLLPMHIIMFAVALILLRVRSMPSQPF-- 357 Query: 360 SRLWSRVRRAMTFQ 373 W V +++T + Sbjct: 358 ---WQAVGKSLTLK 368 >PA3828 [R] COG0795 Predicted permeases Pae Pseudomonas aeruginosa Length = 372 Score = 163 bits (412), Expect = 7e-40, Method: Compositional matrix adjust. Identities = 108/362 (29%), Positives = 186/362 (51%), Gaps = 11/362 (3%) Query: 1 MIFQRALRRELTSTAGGVFTTLFTITLTVMLIKILGQAAGGQVASQDVLALIGFQSLNYM 60 MI R L RE+ T V L I ++ IK L QAA G + + ++ F+ ++ Sbjct: 1 MIVFRYLSREVLVTMSAVSAVLLVIIMSGRFIKYLAQAAQGLLDPGSLFLIMAFRIPGFL 60 Query: 61 PIILILTGFISVLLVMTRSYQDSEIVVWFSCGMSLTRWITPVLRFGWPIMALVAVLSFVV 120 +IL L F+ +LL R Y +SE+ V + GMS R + + + LVA LS + Sbjct: 61 QLILPLGLFLGILLAYGRLYLESEMTVLSATGMSQKRLLGYTMAPALLVAILVAWLSLFL 120 Query: 121 TPWANEQSSEYRSRFEQREDIARVSPGKFQESAAANRIFFVEGISGDASKVRNIFV---- 176 P Q + ++ + + + PG+FQ R+ + E +S D ++ IF+ Sbjct: 121 APQGINQFALLLNKQDTLTEFDTLVPGRFQAMRDGTRVTYTEELSKDRGELAGIFISQKD 180 Query: 177 -NTINQDGKNSVVVAKEGETTVDADGEKFVVMQKGRRYDGSPSLPDFQIVDFERYGLLIG 235 N+ NQ+ S++VA++G + ADG +++++ G RYDG+P +++ + ++ YG+++ Sbjct: 181 LNSSNQERGISILVAEKGTQNIQADGSRYLILHNGYRYDGNPGQANYRAIQYDTYGVML- 239 Query: 236 NQSQTAAGERSAR-ALQMNELLAKRDGFARGELLWRIALPLMALALMLLAIPLSFVNPRA 294 A+ E S R A+ +L + + EL WR++ PL+ + LLA+PLS VNPR Sbjct: 240 -PKPEASSEVSERDAVPTADLFGSDNPRYQAELQWRLSTPLLVFVVTLLAVPLSRVNPRQ 298 Query: 295 GRSLGLLVALLLFVVYSNTVSVFQASVAQQRMSFVMAWWPVH---LIVALLIVGMFALRL 351 GR L LL A+LL++ Y + + + + ++ + W VH L + LL+ LRL Sbjct: 299 GRFLKLLPAILLYMGYLALLIAVRGQLDKGKIPMAIGLWWVHGLFLAIGLLLFYWEPLRL 358 Query: 352 NI 353 + Sbjct: 359 KL 360 >VC2500 [R] COG0795 Predicted permeases Vch Vibrio cholerae Length = 366 Score = 149 bits (376), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 93/338 (27%), Positives = 168/338 (49%), Gaps = 5/338 (1%) Query: 1 MIFQRALRRELTSTAGGVFTTLFTITLTVMLIKILGQAAGGQVASQDVLALIGFQSLNYM 60 MI R L RE + +F LF + L+ I++L A+ G++ + +L+++G Sbjct: 1 MIIVRYLIRETIKSQFAIFFVLFLVFLSQKFIRVLADASDGEIPTSMILSIVGLNMPAMG 60 Query: 61 PIILILTGFISVLLVMTRSYQDSEIVVWFSCGMSLTRWITPVLRFGWPIMALVAVLSFVV 120 ++L L+ +I +LL R Y +SEI V + G+ I L ++ A + + Sbjct: 61 LLMLPLSLYIGILLTFGRLYAESEITVMNATGIGNKFLIRAALYLALITASVAAFNALWL 120 Query: 121 TPWANEQSSEYRSRFEQREDIARVSPGKFQESAAANRIFFVEGISGDASKVRNIFVNTIN 180 PW+ ++ + +F + + G FQ S + + F++ I + K+ N+FV + Sbjct: 121 APWSQDKEAHLMEQFAAENSVDLLQKGHFQRSPDGSSVVFIDNI--ENRKLYNVFVAQLA 178 Query: 181 QDGK--NSVVVAKEGETTVDADGEKFVVMQKGRRYDGSPSLPDFQIVDFERYGLLIGNQS 238 SV+ + G+ +DG + + + G RY+G P+ D+ I +F+ Y LIG Q Sbjct: 179 PRDSILPSVMFSHSGDVKELSDGRQIITLYDGTRYEGVPTRVDYMITNFDSYDGLIG-QR 237 Query: 239 QTAAGERSARALQMNELLAKRDGFARGELLWRIALPLMALALMLLAIPLSFVNPRAGRSL 298 + + ER AL LL D A+ EL WRI+L + L +L +PLS VNPR GR Sbjct: 238 EVKSAERDWEALPTLSLLNNADRRAQAELQWRISLVVCIPLLTMLVVPLSAVNPRQGRFA 297 Query: 299 GLLVALLLFVVYSNTVSVFQASVAQQRMSFVMAWWPVH 336 + A+L+++ Y +S ++++ + ++ WP++ Sbjct: 298 KMGPAILIYLTYFLALSATKSAIEDGSLPVIIGLWPIN 335