BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0001.2995.p         (165 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

RSc1644 [I] COG0245 2C-methyl-D-erythritol 2,4-cyclodiphosphate ...   248   4e-66
NMA1712 [I] COG0245 2C-methyl-D-erythritol 2,4-cyclodiphosphate ...   214   6e-56
NMB1512 [I] COG0245 2C-methyl-D-erythritol 2,4-cyclodiphosphate ...   213   1e-55
PA3627 [I] COG0245 2C-methyl-D-erythritol 2,4-cyclodiphosphate s...   203   1e-52
HI0671 [I] COG0245 2C-methyl-D-erythritol 2,4-cyclodiphosphate s...   197   1e-50

>RSc1644 [I] COG0245 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
           Rso Ralstonia solanacearum
          Length = 168

 Score =  248 bits (633), Expect = 4e-66,   Method: Compositional matrix adjust.
 Identities = 119/156 (76%), Positives = 136/156 (87%)

Query: 7   FRIGQGYDCHALVEGRPLILGGVTIPHKKGLLGHSDADALLHAITDALFGAAALGDIGRH 66
            RIGQGYD HALVEGR LILGGV IPH +GLLGHSDADALLHAITDALFGAA LGDIGRH
Sbjct: 6   IRIGQGYDVHALVEGRKLILGGVEIPHTRGLLGHSDADALLHAITDALFGAAGLGDIGRH 65

Query: 67  FPDTDPQFKGADSRVLLREAAKRLAAAGYTVGNVDATIIAQAPKMAPHIPAMISHVAADL 126
           FPDTDP F GADSRVLLREA +R+  AGY VGNVDAT+IAQ PK+APH+P M++++AADL
Sbjct: 66  FPDTDPAFAGADSRVLLREAVRRVREAGYDVGNVDATVIAQKPKLAPHVPGMVANLAADL 125

Query: 127 GISEGQVNIKAKTNEKMGFLGREEGIATEAVVLIHR 162
           GI+ G+ N+KAKTNEK+GF GRE+GI  +A VLI+R
Sbjct: 126 GIAPGRCNVKAKTNEKLGFEGREDGIVAQAAVLIYR 161


>NMA1712 [I] COG0245 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
           NmA Neisseria meningitidis Z2491
          Length = 160

 Score =  214 bits (545), Expect = 6e-56,   Method: Compositional matrix adjust.
 Identities = 106/156 (67%), Positives = 122/156 (78%)

Query: 7   FRIGQGYDCHALVEGRPLILGGVTIPHKKGLLGHSDADALLHAITDALFGAAALGDIGRH 66
            RIGQGYD H L EGR LILGGV IP +KGLLGHSDADALLHA+TDAL GAA LGDIG H
Sbjct: 4   IRIGQGYDVHQLTEGRKLILGGVEIPFEKGLLGHSDADALLHAVTDALLGAAGLGDIGSH 63

Query: 67  FPDTDPQFKGADSRVLLREAAKRLAAAGYTVGNVDATIIAQAPKMAPHIPAMISHVAADL 126
           FPDT  +FK ADSRVLLR A + + A G+   NVD T+IAQ PK+APHIP M +++AADL
Sbjct: 64  FPDTAAEFKDADSRVLLRAAYQSVQAQGWQAVNVDTTVIAQKPKLAPHIPQMRANIAADL 123

Query: 127 GISEGQVNIKAKTNEKMGFLGREEGIATEAVVLIHR 162
           GI    VNIK KTNEK+G+LGR EGI ++A VL+ R
Sbjct: 124 GIDISCVNIKGKTNEKLGYLGRMEGIESQAAVLLVR 159


>NMB1512 [I] COG0245 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
           Nme Neisseria meningitidis MC58
          Length = 160

 Score =  213 bits (543), Expect = 1e-55,   Method: Compositional matrix adjust.
 Identities = 106/156 (67%), Positives = 121/156 (77%)

Query: 7   FRIGQGYDCHALVEGRPLILGGVTIPHKKGLLGHSDADALLHAITDALFGAAALGDIGRH 66
            RIGQGYD H L EGR LILGGV IP +KGLLGHSDADALLHA+TDAL GAA LGDIG H
Sbjct: 4   IRIGQGYDVHQLTEGRKLILGGVEIPFEKGLLGHSDADALLHAVTDALLGAAGLGDIGSH 63

Query: 67  FPDTDPQFKGADSRVLLREAAKRLAAAGYTVGNVDATIIAQAPKMAPHIPAMISHVAADL 126
           FPDT  +FK ADSRVLLR A + + A G+   NVD T+IAQ PK+APHIP M +++AADL
Sbjct: 64  FPDTAAEFKDADSRVLLRAAYQSVQAQGWQAVNVDTTVIAQKPKLAPHIPQMRANIAADL 123

Query: 127 GISEGQVNIKAKTNEKMGFLGREEGIATEAVVLIHR 162
           GI    VNIK KTNEK+G+LGR EGI  +A VL+ R
Sbjct: 124 GIDISCVNIKGKTNEKLGYLGRMEGIEAQAAVLLVR 159


>PA3627 [I] COG0245 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
           Pae Pseudomonas aeruginosa
          Length = 157

 Score =  203 bits (516), Expect = 1e-52,   Method: Compositional matrix adjust.
 Identities = 100/154 (64%), Positives = 116/154 (75%)

Query: 7   FRIGQGYDCHALVEGRPLILGGVTIPHKKGLLGHSDADALLHAITDALFGAAALGDIGRH 66
            RIG GYD H   EG  + LGGV IPHK GL+ HSD D LLHA++DAL GAAALGDIG+H
Sbjct: 1   MRIGHGYDVHRFGEGDFITLGGVRIPHKHGLVAHSDGDVLLHALSDALLGAAALGDIGKH 60

Query: 67  FPDTDPQFKGADSRVLLREAAKRLAAAGYTVGNVDATIIAQAPKMAPHIPAMISHVAADL 126
           FPDTDP+FKGADSR LLR     +A  G+ VGNVDATI+AQAPKMAPHI  M   +A DL
Sbjct: 61  FPDTDPRFKGADSRALLRHVVAIVAEKGWKVGNVDATIVAQAPKMAPHIETMRGLIAEDL 120

Query: 127 GISEGQVNIKAKTNEKMGFLGREEGIATEAVVLI 160
           G++  QVN+KA T E++GF GREEGIA  AV L+
Sbjct: 121 GVAVDQVNVKATTTERLGFTGREEGIAVHAVALL 154


>HI0671 [I] COG0245 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
           Hin Haemophilus influenzae
          Length = 158

 Score =  197 bits (500), Expect = 1e-50,   Method: Compositional matrix adjust.
 Identities = 97/157 (61%), Positives = 116/157 (73%)

Query: 7   FRIGQGYDCHALVEGRPLILGGVTIPHKKGLLGHSDADALLHAITDALFGAAALGDIGRH 66
            RIG G+D HA  E RPLI+GGV +P+  G + HSD D  LHA+TDA+ GAAALGDIG+ 
Sbjct: 2   IRIGHGFDVHAFGEDRPLIIGGVEVPYHTGFIAHSDGDVALHALTDAILGAAALGDIGKL 61

Query: 67  FPDTDPQFKGADSRVLLREAAKRLAAAGYTVGNVDATIIAQAPKMAPHIPAMISHVAADL 126
           FPDTD Q+K ADSR LLREA +++   GY +GNVD TIIAQAPKM PHI AM + +A DL
Sbjct: 62  FPDTDMQYKNADSRGLLREAFRQVQEKGYKIGNVDITIIAQAPKMRPHIDAMRAKIAEDL 121

Query: 127 GISEGQVNIKAKTNEKMGFLGREEGIATEAVVLIHRQ 163
                QVN+KA T EK+GF GR+EGIA EAV L+ RQ
Sbjct: 122 QCDIEQVNVKATTTEKLGFTGRQEGIACEAVALLIRQ 158