BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.2994.p (221 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1643 [I] COG1211 4-diphosphocytidyl-2-methyl-D-erithritol syn... 183 2e-46 HI0672 [I] COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synt... 167 2e-41 ispD [I] COG1211 4-diphosphocytidyl-2-methyl-D-erithritol syntha... 151 9e-37 ZygbP [I] COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synth... 150 2e-36 ECs3601 [I] COG1211 4-diphosphocytidyl-2-methyl-D-erithritol syn... 150 2e-36 >RSc1643 [I] COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase Rso Ralstonia solanacearum Length = 253 Score = 183 bits (465), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 121/231 (52%), Positives = 137/231 (59%), Gaps = 26/231 (11%) Query: 2 GGQIPKQYMMLAGQPMLQHALQTFATHARIAHTFVVVSAEDGWIDTLMTPALQARVSIL- 60 GG +PKQY LAG+PML H +Q F A I VV S PAL AR L Sbjct: 25 GGDLPKQYQPLAGRPMLWHTVQAFLASAAIDRVVVVTSPG--------APALAARFPGLG 76 Query: 61 ---------RVGGPTRQDSVFNGLNAMRA-EAGDADWVLVHDAARPGLDAALIDRLLDAL 110 GG +R SV NGL A+R A + DWVLVHDAARPGL ALI RL+ A+ Sbjct: 77 FDAARLVEVDCGGDSRHASVTNGLAALRGLGAHEDDWVLVHDAARPGLTPALIARLVGAV 136 Query: 111 EGD---EVGGLLALPMVDTLKRSDAQCPARSLETVPRAGLWAAQTPQMFPYTLLQRALHQ 167 E D VGG+LALP+ DTLKR+DA ETVPR GLW AQTPQMFP LLQRAL + Sbjct: 137 EADGGQAVGGILALPVADTLKRADAG--QHIAETVPRGGLWQAQTPQMFPLGLLQRALSE 194 Query: 168 AQQQGRLGEITDDASAIEMLGLRPRLVEGSPRNLKVTLAQDAALAEFFLKG 218 A R+ +TD+ASAIE G RP LV G+ RN KVT D ALAE L G Sbjct: 195 ALTAQRI--VTDEASAIEAAGHRPLLVAGALRNFKVTYPDDFALAEAILAG 243 >HI0672 [I] COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase Hin Haemophilus influenzae Length = 225 Score = 167 bits (423), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 103/218 (47%), Positives = 135/218 (61%), Gaps = 17/218 (7%) Query: 1 MGGQIPKQYMMLAGQPMLQHALQTFATHARIAHTFVVVSAEDGWIDTL-MTPALQARVSI 59 M PKQY+ L G+ +L+H L ++ ++ + VS +D +I TL + P +Q Sbjct: 18 MQADKPKQYLTLLGKTLLEHTLDVMLSYPAVSKIILAVSKDDPYISTLSLDPKIQ----- 72 Query: 60 LRVGGPTRQDSVFNGLNAMRAEAGDADWVLVHDAARPGLDAALIDRLLDALEGDEVGGLL 119 L GG TR +SV NGLNA+ A WVLVHDAARP L A ID+LL A+E D+ G +L Sbjct: 73 LVEGGTTRAESVLNGLNAI---AEKNAWVLVHDAARPCLQHADIDKLL-AIE-DKQGAIL 127 Query: 120 ALPMVDTLKRSDAQ-CPARSLETVPRAGLWAAQTPQMFPYTLLQRALHQAQQQGRLGEIT 178 A+P+ DT+KR+D Q C ++T R+ LW A TPQ FP +L+ AL QQG IT Sbjct: 128 AIPVTDTIKRADNQQC---IVKTEDRSQLWQAMTPQFFPVDILRDALSTGIQQG--ANIT 182 Query: 179 DDASAIEMLGLRPRLVEGSPRNLKVTLAQDAALAEFFL 216 D+ASAIE+ G RP LV G NLKVT +D ALAEF+L Sbjct: 183 DEASAIELAGFRPHLVAGRSDNLKVTRPEDLALAEFYL 220 >ispD [I] COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase Eco Escherichia coli K12 Length = 236 Score = 151 bits (382), Expect = 9e-37, Method: Compositional matrix adjust. Identities = 93/218 (42%), Positives = 124/218 (56%), Gaps = 13/218 (5%) Query: 1 MGGQIPKQYMMLAGQPMLQHALQTFATHARIAHTFVVVSAEDGWIDTLMTPALQARVSIL 60 M + PKQY+ + Q +L+H++ H R+ + +S D L A +++++ Sbjct: 21 MQTECPKQYLSIGNQTILEHSVHALLAHPRVKRVVIAISPGDSRFAQLPL-ANHPQITVV 79 Query: 61 RVGGPTRQDSVFNGLNAMRAEAGDADWVLVHDAARPGLDAALIDRLLDALEGDEVGGLLA 120 GG R DSV GL A AGDA WVLVHDAARP L + RLL E GG+LA Sbjct: 80 D-GGDERADSVLAGLKA----AGDAQWVLVHDAARPCLHQDDLARLLALSETSRTGGILA 134 Query: 121 LPMVDTLKRSDAQCPARS--LETVPRAGLWAAQTPQMFPYTLLQRALHQAQQQGRLGEIT 178 P+ DT+KR++ P ++ TV R GLW A TPQ FP LL L +A +G IT Sbjct: 135 APVRDTMKRAE---PGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEG--ATIT 189 Query: 179 DDASAIEMLGLRPRLVEGSPRNLKVTLAQDAALAEFFL 216 D+ASA+E G P+LVEG N+KVT +D ALAEF+L Sbjct: 190 DEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYL 227 >ZygbP [I] COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase EcZ Escherichia coli O157:H7 EDL933 Length = 236 Score = 150 bits (380), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 93/218 (42%), Positives = 124/218 (56%), Gaps = 13/218 (5%) Query: 1 MGGQIPKQYMMLAGQPMLQHALQTFATHARIAHTFVVVSAEDGWIDTLMTPALQARVSIL 60 M + PKQY+ + Q +L+H++ H R+ + +S D L A +++++ Sbjct: 21 MQTECPKQYLSIGNQTILEHSVYALLAHPRVKRVVIAISPGDSRFAQLPL-ANHPQITVV 79 Query: 61 RVGGPTRQDSVFNGLNAMRAEAGDADWVLVHDAARPGLDAALIDRLLDALEGDEVGGLLA 120 GG R DSV GL A AGDA WVLVHDAARP L + RLL E GG+LA Sbjct: 80 D-GGDERADSVLAGLKA----AGDAQWVLVHDAARPCLHQDDLARLLALSETSRTGGILA 134 Query: 121 LPMVDTLKRSDAQCPARS--LETVPRAGLWAAQTPQMFPYTLLQRALHQAQQQGRLGEIT 178 P+ DT+KR++ P ++ TV R GLW A TPQ FP LL L +A +G IT Sbjct: 135 APVRDTMKRAE---PGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEG--AAIT 189 Query: 179 DDASAIEMLGLRPRLVEGSPRNLKVTLAQDAALAEFFL 216 D+ASA+E G P+LVEG N+KVT +D ALAEF+L Sbjct: 190 DEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYL 227 >ECs3601 [I] COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase Ecs Escherichia coli O157:H7 Length = 236 Score = 150 bits (380), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 93/218 (42%), Positives = 124/218 (56%), Gaps = 13/218 (5%) Query: 1 MGGQIPKQYMMLAGQPMLQHALQTFATHARIAHTFVVVSAEDGWIDTLMTPALQARVSIL 60 M + PKQY+ + Q +L+H++ H R+ + +S D L A +++++ Sbjct: 21 MQTECPKQYLSIGNQTILEHSVYALLAHPRVKRVVIAISPGDSRFAQLPL-ANHPQITVV 79 Query: 61 RVGGPTRQDSVFNGLNAMRAEAGDADWVLVHDAARPGLDAALIDRLLDALEGDEVGGLLA 120 GG R DSV GL A AGDA WVLVHDAARP L + RLL E GG+LA Sbjct: 80 D-GGDERADSVLAGLKA----AGDAQWVLVHDAARPCLHQDDLARLLALSETSRTGGILA 134 Query: 121 LPMVDTLKRSDAQCPARS--LETVPRAGLWAAQTPQMFPYTLLQRALHQAQQQGRLGEIT 178 P+ DT+KR++ P ++ TV R GLW A TPQ FP LL L +A +G IT Sbjct: 135 APVRDTMKRAE---PGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEG--AAIT 189 Query: 179 DDASAIEMLGLRPRLVEGSPRNLKVTLAQDAALAEFFL 216 D+ASA+E G P+LVEG N+KVT +D ALAEF+L Sbjct: 190 DEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYL 227