BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.2917.p (296 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1223 [O] COG0330 Membrane protease subunits, stomatin/prohibi... 363 e-100 PA4941 [O] COG0330 Membrane protease subunits, stomatin/prohibit... 230 3e-60 PM0118 [O] COG0330 Membrane protease subunits, stomatin/prohibit... 207 3e-53 HI0150 [O] COG0330 Membrane protease subunits, stomatin/prohibit... 207 3e-53 YPO0376 [O] COG0330 Membrane protease subunits, stomatin/prohibi... 199 8e-51 >RSc1223 [O] COG0330 Membrane protease subunits, stomatin/prohibitin homologs Rso Ralstonia solanacearum Length = 304 Score = 363 bits (931), Expect = e-100, Method: Compositional matrix adjust. Identities = 171/295 (57%), Positives = 227/295 (76%), Gaps = 1/295 (0%) Query: 1 MGRLVTSVIVAVVAIWLASSTIFVVDQRSSAIVFALGEVKQVITEPGLHFKLPPPFQNVM 60 M RL+++++ V+A+ + SS +FVVDQR A+VFA GE+KQVI EPGLHFKLPPP QNV+ Sbjct: 1 MNRLISALVALVIALAVLSSVVFVVDQRQYAVVFAFGEIKQVIKEPGLHFKLPPPLQNVI 60 Query: 61 YLDKRIQTLDTPDADRFITAEKMNVLVDAYVKWRIVDPRLYFVSFGADERRTQDRLSQIV 120 ++DKR+ T+D ADRFITAEK N+LVD +VKWR+ DPRL++VSF D R QD ++Q + Sbjct: 61 FMDKRLMTIDVAGADRFITAEKKNLLVDWFVKWRVSDPRLFYVSFKGDNRLAQDSMTQKI 120 Query: 121 KAALNDEITKRTVREVISSQRNSVMDAIQARVANEAKQIGVEIIDVRLRRVDYVDQINNS 180 + DE +RTV +V+S+ R +VM +I V + +GV+IIDVRL+RVD + + S Sbjct: 121 NSIARDEFARRTVSDVVSTDREAVMQSILKGVQEYGRSVGVDIIDVRLKRVDLLASVTES 180 Query: 181 VFERMKSERVRVANELRSTGAAESEKIRADADRQRVVILAEAYRESEKIRGAGDAKASQI 240 V+ RM++ER RVANELRSTGAAE EKIRADADRQR V+LA+AYRE++KI+G GDA+A+ I Sbjct: 181 VYRRMEAERKRVANELRSTGAAEGEKIRADADRQREVVLADAYREAQKIKGEGDARAADI 240 Query: 241 YAQAFGQNPDFYKFYRSLEAYRASFKSRHDVMVVDPSSEFFKYFKGI-GGATSAA 294 YA AFG++P F F+RS+EAYRASF+ R DVMV+ P S+FFK+ +G GG S A Sbjct: 241 YADAFGRDPQFAAFWRSMEAYRASFRDRKDVMVLQPGSDFFKFMRGPNGGGQSVA 295 >PA4941 [O] COG0330 Membrane protease subunits, stomatin/prohibitin homologs Pae Pseudomonas aeruginosa Length = 289 Score = 230 bits (586), Expect = 3e-60, Method: Compositional matrix adjust. Identities = 134/281 (47%), Positives = 193/281 (68%), Gaps = 3/281 (1%) Query: 5 VTSVIVAVVAIWLASSTIFVVDQRSSAIVFALGEVKQVITEPGLHFKLPPPFQNVMYLDK 64 + ++IV VVA + ++++VV Q A++ G V + +PGLHFK+P Q V D Sbjct: 6 LIALIVGVVAAIVLWNSVYVVQQTERAVMLRFGRVVESDVKPGLHFKIPYVNQ-VRKFDA 64 Query: 65 RIQTLDTPDADRFITAEKMNVLVDAYVKWRIVDPRLYFVSFGADERRTQDRLSQIVKAAL 124 R+ TLD P RF+T EK V+VDAY KWR+ D ++ + ++ +RLS+ ++A L Sbjct: 65 RLLTLDAP-TQRFLTLEKKAVMVDAYAKWRVADAERFYTATSGLKQIADERLSRRLEAGL 123 Query: 125 NDEITKRTVREVISSQRNSVMDAIQARVANEA-KQIGVEIIDVRLRRVDYVDQINNSVFE 183 D+ KRT+ EV+S +R+++M I A + A K++G+E+IDVR++ +D ++N SVFE Sbjct: 124 RDQFGKRTLHEVVSGERDALMGDITASLNRMAQKELGIEVIDVRVKAIDLPKEVNRSVFE 183 Query: 184 RMKSERVRVANELRSTGAAESEKIRADADRQRVVILAEAYRESEKIRGAGDAKASQIYAQ 243 RM +ER R A E R+ G +E IRADADRQR VI+AEAYRESE+ RG GD+KA+ IYA+ Sbjct: 184 RMSTEREREAREHRAKGRELAEGIRADADRQRRVIVAEAYRESEETRGDGDSKAAAIYAK 243 Query: 244 AFGQNPDFYKFYRSLEAYRASFKSRHDVMVVDPSSEFFKYF 284 A+ Q+P+FY FYRSL+AYR SF + DV+V+DPSSEFF+Y Sbjct: 244 AYNQDPEFYSFYRSLKAYRESFAEKRDVLVLDPSSEFFRYL 284 >PM0118 [O] COG0330 Membrane protease subunits, stomatin/prohibitin homologs Pmu Pasteurella multocida Length = 295 Score = 207 bits (527), Expect = 3e-53, Method: Compositional matrix adjust. Identities = 110/295 (37%), Positives = 187/295 (63%), Gaps = 14/295 (4%) Query: 1 MGRLVTSVIVAVVAIWLASSTIFVVDQRSSAIVFALGEV------KQVITEPGLHFKLPP 54 M + +T VIV + AI S+I +V + + I+ +V K V+ PGLHFK+P Sbjct: 1 MRKFLTPVIVVIAAILY--SSIVIVSEGTRGIMLRFSKVHRDADNKVVVYNPGLHFKIPF 58 Query: 55 PFQNVMYLDKRIQTLDTPDADRFITAEKMNVLVDAYVKWRIVD-PRLYFVSFGADERRTQ 113 ++ LD RI+TLD ADRF+T EK ++LVD+YVKWRI D R Y + G D + Sbjct: 59 -IDSIKILDARIRTLDG-QADRFVTVEKKDLLVDSYVKWRISDFGRFYTATGGGDYAQAS 116 Query: 114 DRLSQIVKAALNDEITKRTVREVISSQRNSVMDAIQARV---ANEAKQIGVEIIDVRLRR 170 + L + V L E RT+++++S R +M+ + + + ++G+E++DVR+++ Sbjct: 117 NLLRRKVNDRLRSETGSRTIKDIVSGTRGELMEGARKALNTGPDSTAELGIEVVDVRVKQ 176 Query: 171 VDYVDQINNSVFERMKSERVRVANELRSTGAAESEKIRADADRQRVVILAEAYRESEKIR 230 ++ D++++S+++RM++ER VA E RS G ++ I+AD DR+ +ILA A R ++++R Sbjct: 177 INLPDEVSSSIYQRMRAERDAVAREHRSQGREKAAFIQADVDRKVTLILANANRTAQELR 236 Query: 231 GAGDAKASQIYAQAFGQNPDFYKFYRSLEAYRASFKSRHDVMVVDPSSEFFKYFK 285 G+GDA A+++++ AF Q P FY F RSL+AY +SF + ++M++ P S+FF++ + Sbjct: 237 GSGDATAAKVFSDAFSQEPQFYSFLRSLKAYESSFANSDNMMILKPDSDFFRFMQ 291 >HI0150 [O] COG0330 Membrane protease subunits, stomatin/prohibitin homologs Hin Haemophilus influenzae Length = 295 Score = 207 bits (526), Expect = 3e-53, Method: Compositional matrix adjust. Identities = 111/295 (37%), Positives = 188/295 (63%), Gaps = 14/295 (4%) Query: 1 MGRLVTSVIVAVVAIWLASSTIFVVDQRSSAIVFALGEV------KQVITEPGLHFKLPP 54 M R + VI + A+ S+I VV + + I+ +V K V+ EPGLHFK+P Sbjct: 1 MRRFLLPVIFVIAAV--VYSSIVVVTEGTRGIMLRFNKVQRDADNKVVVYEPGLHFKVPL 58 Query: 55 PFQNVMYLDKRIQTLDTPDADRFITAEKMNVLVDAYVKWRIVD-PRLYFVSFGADERRTQ 113 ++ LD RI+TLD A RF+T EK ++LVD+YVKW+I D R Y + G D + Sbjct: 59 -IDSIKVLDARIRTLDGS-ATRFVTVEKKDLLVDSYVKWKISDFGRFYTSTGGGDYAQAA 116 Query: 114 DRLSQIVKAALNDEITKRTVREVISSQRNSVMDAIQARVA---NEAKQIGVEIIDVRLRR 170 + LS+ V L EI RT+++++S R +M+ + ++ + ++G+E+IDVR+++ Sbjct: 117 NLLSRKVNDRLRSEIGSRTIKDIVSGTRGELMEGAKKALSSGQDSTAELGIEVIDVRVKQ 176 Query: 171 VDYVDQINNSVFERMKSERVRVANELRSTGAAESEKIRADADRQRVVILAEAYRESEKIR 230 ++ D++++S+++RM++ER VA E RS G ++ I+AD DR+ +ILA A + ++++R Sbjct: 177 INLPDEVSSSIYQRMRAERDAVAREHRSQGKEKAAFIQADVDRKVTLILANANKTAQELR 236 Query: 231 GAGDAKASQIYAQAFGQNPDFYKFYRSLEAYRASFKSRHDVMVVDPSSEFFKYFK 285 G+GDA A+++Y+ AF Q P F+ F RSL+AY ASF + ++M++ P S+FF++ + Sbjct: 237 GSGDAAAAKLYSDAFAQEPQFFTFVRSLKAYEASFANSDNIMILKPDSDFFRFMQ 291 >YPO0376 [O] COG0330 Membrane protease subunits, stomatin/prohibitin homologs Ype Yersinia pestis Length = 334 Score = 199 bits (505), Expect = 8e-51, Method: Compositional matrix adjust. Identities = 124/322 (38%), Positives = 187/322 (58%), Gaps = 47/322 (14%) Query: 8 VIVAVVAIWLASSTIFVVDQRSSAIVFALGEV------KQVITEPGLHFKLPPPFQNVMY 61 +IV VV I L +S +FVV++ IV G+V K ++ PGLHFK+ P + V Sbjct: 7 LIVVVVLIALFAS-LFVVEEGQRGIVLRFGKVLRDSDNKPLVYAPGLHFKI-PFIETVKR 64 Query: 62 LDKRIQTLDTPDADRFITAEKMNVLVDAYVKWRIVD-PRLYFVSFGADERRTQDRLSQIV 120 LD RIQT+D ADRF+T EK +++VD+Y+KWRI D R Y + G D + + L + Sbjct: 65 LDARIQTMDN-QADRFVTNEKKDLIVDSYLKWRISDFSRYYLATGGGDVSQAEVLLKRKF 123 Query: 121 KAALNDEITKRTVREVISSQR----NSVMDAIQ-ARVANEA------------------- 156 L EI + VR++++ R + V DA+ V +EA Sbjct: 124 SDRLRSEIGRLNVRDIVTDSRGRLTSDVRDALNTGSVGDEAATTEADDAIASAAARVEQE 183 Query: 157 ---KQ----------IGVEIIDVRLRRVDYVDQINNSVFERMKSERVRVANELRSTGAAE 203 KQ +G+E++DVR+++++ ++++++F+RM++ER VA RS G E Sbjct: 184 TRGKQPAVNPNSMAALGIEVVDVRIKQINLPAEVSDAIFQRMRAEREAVARRHRSQGQEE 243 Query: 204 SEKIRADADRQRVVILAEAYRESEKIRGAGDAKASQIYAQAFGQNPDFYKFYRSLEAYRA 263 +EK+RA AD + LAEA R++ RG GDA+A++++A+AF Q+PDFY F RSL AY Sbjct: 244 AEKLRATADYEVTRTLAEAERQARITRGGGDAEAARLFAEAFSQDPDFYAFIRSLRAYEN 303 Query: 264 SFKSRHDVMVVDPSSEFFKYFK 285 SF S +DVMV+ P S+FF+Y K Sbjct: 304 SFSSGNDVMVLSPDSDFFRYMK 325