BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.2901.p (274 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value VCA0034 [T] COG1639 Predicted signal transduction protein Vch Vi... 152 6e-37 TM0854 [T] COG1639 Predicted signal transduction protein Tma The... 95 2e-19 PA0356 [T] COG1639 Predicted signal transduction protein Pae Pse... 74 4e-13 TP0073 Non COG 69 2e-11 PA5346_2 [T] COG1639 Predicted signal transduction protein Pae P... 67 3e-11 >VCA0034 [T] COG1639 Predicted signal transduction protein Vch Vibrio cholerae Length = 290 Score = 152 bits (385), Expect = 6e-37, Method: Compositional matrix adjust. Identities = 78/224 (34%), Positives = 134/224 (59%), Gaps = 6/224 (2%) Query: 1 MNL--EALFQQQTALPSIPKVVQEVIESFNNESVSIEEIAKKLAADQVLSAKILRLANSS 58 MN+ + + LP + KV+QE+++ N V +++KK+ DQ+L+A++LR+ANS+ Sbjct: 13 MNMVKNTMLNRLNELPRLSKVLQELLDMANQPDVDFHQLSKKITLDQILTARLLRMANSA 72 Query: 59 YYHVSRTVGTVEDAVLMLGFMTVRTLVVSTGMAGSFKKLPGVDLKLFWRYSLDTAIVAKW 118 Y+ + + TV DA++ +G +VRTLVV++ ++ +F K+ +DL +W + +TA++A Sbjct: 73 YFGGNGHIATVNDAIIRVGIESVRTLVVASVLSSTFPKIETLDLNDYWTNTFETALIASK 132 Query: 119 LAKQAKLNSDFAFTVGLMHAIGQLVMHAGMP-EQALQVDKVAGPLDARRLDVERKSFGYD 177 +A+Q L+ FT G++H IG+L++H MP E +L K+A +D L + + G Sbjct: 133 IAEQVGLDKSETFTTGVLHNIGELMIHTLMPTEASLIQQKIAQGMDP--LSAQEEVLGIS 190 Query: 178 FADVGAELARRWRFPDEFGQVIKAFPQPLEGQFDP-FAAIVHLA 220 +GA LA+ W+FP E IK F +P E + P A +H A Sbjct: 191 APRIGAMLAKEWKFPSEMVDAIKHFDEPREAEISPKLAVAIHFA 234 >TM0854 [T] COG1639 Predicted signal transduction protein Tma Thermotoga maritima Length = 285 Score = 94.7 bits (234), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 66/203 (32%), Positives = 104/203 (51%), Gaps = 9/203 (4%) Query: 13 LPSIPKVVQEVIESFNNESVSIEEIAKKLAADQVLSAKILRLANSSYYHVSRTVGTVEDA 72 LPS VVQ +I + S E+A L D LSA++L+LANS+YY V R + T+ +A Sbjct: 16 LPSPNVVVQRIIAVCSKPDASSTEVANTLMMDASLSARVLKLANSAYYGVPRKITTLSEA 75 Query: 73 VLMLGFMTVRTLVVSTGMAGS-FKK-LPGVDLKLFWRYSLDTAIVAKWLAKQAKLN-SDF 129 V++LGF TVR L +S FK G+D + W + + +AI ++ +A+ + Sbjct: 76 VMILGFKTVRNLALSVFTYDMVFKNSSSGIDREKLWEHFIASAIASETVAETMGYPLKEE 135 Query: 130 AFTVGLMHAIGQLVMHAGMPEQALQVDKVAGPLDARRLDVERKSFGYDFADVGAELARRW 189 F GL+H +G++V + K+A +D+E + ++VGA+L R+W Sbjct: 136 IFIAGLLHDLGKVVYDLLFSDILETEAKIAQKTKKNLIDIEEELGIPPHSEVGAKLLRKW 195 Query: 190 RFPD------EFGQVIKAFPQPL 206 FPD EF ++ P L Sbjct: 196 NFPDLLVLSAEFHHNVEGNPNEL 218 >PA0356 [T] COG1639 Predicted signal transduction protein Pae Pseudomonas aeruginosa Length = 274 Score = 73.9 bits (180), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 50/169 (29%), Positives = 83/169 (49%), Gaps = 3/169 (1%) Query: 34 IEEIAKKLAADQVLSAKILRLANSSYYHVSRTVGTVEDAVLMLGFMTVRTLVVSTGMAGS 93 ++ IA+ ++ D LS +L+L NS ++ ++ + +++ AV +LG +V L+ + + G Sbjct: 22 LKNIARLISQDPGLSGALLKLVNSPFFGLANRITSIQRAVNLLGSRSVINLINAQSIKGE 81 Query: 94 FKKLPGVDLKLFWRYSLDTAIVAKWLAKQAKLNS-DFAFTVGLMHAIGQLVMHAGMPE-Q 151 V L FW + D A+ LAK+ S D A+ +GL H G +M P Sbjct: 82 MSDDTIVTLNRFWDTAQDVAMSCLSLAKRIGYESVDEAYALGLFHNCGIPLMLKRFPHYM 141 Query: 152 ALQVDKVAGPLDARR-LDVERKSFGYDFADVGAELARRWRFPDEFGQVI 199 A+ + A D RR +D E + + A VG AR WR P+ + I Sbjct: 142 AVLEEAYAAASDERRVVDTENRVLNTNHAVVGYYTARSWRLPEHVCEAI 190 >TP0073 Non COG Length = 513 Score = 68.6 bits (166), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 53/220 (24%), Positives = 100/220 (45%), Gaps = 11/220 (5%) Query: 13 LPSIPKVVQEVIESFNNESVSIEEIAKKLAADQVLSAKILRLANSSYYHVSRTVGTVEDA 72 +P +P + E+ + N V + +I ++ D L +L+L NS+ + +++ + +A Sbjct: 254 IPQLPSKLLEIQRAIENPDVQLSDIVALISQDVALVTDLLKLVNSARFGMNKRCLDISEA 313 Query: 73 VLMLGFMTVRTLVVSTGMAGSFKKLPGVDLKLFWRYSLDTAIVAKWLAKQAKLNSDFA-- 130 V +G ++ L+ S G AG + + K W + T A LAK + A Sbjct: 314 VKRVGLRGLQNLLYSVG-AGRVLQSTDDERKQLWNQAYRTGYFALGLAKATGDQALIADS 372 Query: 131 FTVGLMHAIGQLVMHAGMPEQALQVDKVAGP--LDARRLDVERKSFGYDFADVGAELARR 188 + GL+H +G++V + PE +++ ++ + LD G+ A++GA LA+R Sbjct: 373 YICGLLHNLGEVVFTSAYPEMLIKLTEIQAERNIPPHVLDTIMSDVGH--AEIGAALAQR 430 Query: 189 WRFPDEFGQVIK---AFPQPLEGQFDPFAAIVHLAAWRAR 225 W P+ I+ P E ++ P + V A R Sbjct: 431 WNLPEPVINTIRFHHNLPHAPE-EYKPLISTVAFANMTIR 469 >PA5346_2 [T] COG1639 Predicted signal transduction protein Pae Pseudomonas aeruginosa Length = 293 Score = 67.4 bits (163), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 60/251 (23%), Positives = 109/251 (43%), Gaps = 10/251 (3%) Query: 7 FQQQTALPSIPKVVQEVIESFNNESVSIEEIAKKLAADQVLSAKILRLANSSYYHVSRTV 66 +Q +P +P+ Q++I+ + + S+++I + D L+A+++ A S YY + Sbjct: 13 LEQTIEIPPLPQTAQKIIKLRVDPNASVDDITGLVETDPALAAQVVSWAASPYYAAPGKI 72 Query: 67 GTVEDAVL-MLGFMTVRTLV--VSTGMAGSFKKLPGVDLKLFWRYSLDTAIVAKWLA--- 120 +VEDA++ +LGF V L ++ G + S K +W+ ++ TA V + L Sbjct: 73 RSVEDAIVRVLGFDLVINLALGLALGKSLSLPKDQPQQATPYWQQAIYTAAVIEGLTRAM 132 Query: 121 -KQAKLNSDFAFTVGLMHAIGQLVM-HAGMPEQALQVDKVAGPLDARRLDVERKSFGYDF 178 ++ + S ++ GL+H G LV+ H P +L + +E+ G Sbjct: 133 PRELRPESGLSYLGGLLHNFGYLVLAHVFPPHFSLICRHLEVNPHLGHAYIEQHLLGITR 192 Query: 179 ADVGAELARRWRFPDEFGQVIKAFPQPLEGQFDPFAAIVHLAAWRARAQENQYSEDEMES 238 +GA L R W PD+ ++ P P A +L R N D + Sbjct: 193 EQIGAWLMRVWDMPDDLYCALRFQQDP--SYTGPNAVYANLICLTNRLLRNSGIGDGTQQ 250 Query: 239 TFPVDVAAKLG 249 P + +LG Sbjct: 251 AIPAALYERLG 261