BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.2855.p (447 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0291 [M] COG0845 Membrane-fusion protein Rso Ralstonia solana... 472 e-133 XF2398 [M] COG0845 Membrane-fusion protein Xfa Xylella fastidios... 308 2e-83 NMB1738 [M] COG0845 Membrane-fusion protein Nme Neisseria mening... 273 5e-73 NMA1996 [M] COG0845 Membrane-fusion protein NmA Neisseria mening... 235 2e-61 VC1447 [M] COG0845 Membrane-fusion protein Vch Vibrio cholerae 202 1e-51 >RSp0291 [M] COG0845 Membrane-fusion protein Rso Ralstonia solanacearum Length = 447 Score = 472 bits (1214), Expect = e-133, Method: Compositional matrix adjust. Identities = 243/447 (54%), Positives = 325/447 (72%) Query: 1 MSLHHRSQAWMALLLRYRRRFLQAWRDRHLQPEGFFNQQEAEFLPAALSLQEAPDSPSLR 60 MSL HR +AW L RYR F W+ R F EAEFLPAALSLQ P SP+ R Sbjct: 1 MSLRHRWEAWSELWQRYRDVFRHYWKQRDALSLPRFEVHEAEFLPAALSLQAQPVSPAGR 60 Query: 61 WTARLLVAMVLLALAWSLIGQIDIVVSANGKVIPSARTKTIASVEVASVRAILVREGQFV 120 W AR+L+ ++++ L WS++G++DI+V+A GK+IPS RTKTIA+VEVA+VR + V EGQ V Sbjct: 61 WVARILMLLIVVLLLWSILGKVDIIVNATGKIIPSERTKTIAAVEVATVRKLHVEEGQIV 120 Query: 121 QAGQVLLELDASSSDAERDKAADAVAQARLQAARAAAMMQAVQQLRAPELQDVADVSLAQ 180 +AG VL+ELDA +SD+ERDKA ARLQAAR+ A++ A+ Q P L + + + Sbjct: 121 KAGDVLIELDARASDSERDKAVGNEQLARLQAARSRALIGALDQGGTPHLPPLEGIPPER 180 Query: 181 WESVRRQLQGQYQDFRARLDRFDDEIVRYTKALRLASQRATDYQELMADHTVSRHAWLEK 240 + L Q++D+ A+L+R D EI RY +AL LA+QRA DY +L DH VS+HA+LEK Sbjct: 181 LHEAEQHLADQWRDYTAKLNRLDGEIRRYAEALPLATQRARDYADLAKDHDVSQHAYLEK 240 Query: 241 EQARVDLQGQLTDARNQRAALLAQTQKEAHDSRLEAEKIIEAAQKDQRRAQERSKLLHLR 300 EQAR+D++GQL DAR+Q+AAL A+T++ A DS +A+K++ + +D RRA S+ L L Sbjct: 241 EQARIDIEGQLRDARDQKAALTAETRRVAQDSLTDAKKVLGESSEDARRASVHSEQLRLV 300 Query: 301 APVSGTVQQLNVHTIGGVVPAAQPLMQIVPEDGEIEVEAWLDNKDVGFVEVGQEVEVKVD 360 APVSGTVQQL VHT+G VP AQPLMQIVPE +EVEA+L+NKDVGFV+ GQ+ +VK+D Sbjct: 301 APVSGTVQQLTVHTVGTAVPVAQPLMQIVPEQSVVEVEAFLENKDVGFVQEGQDAQVKID 360 Query: 361 AFDYTKYGTVAGRVVQVSRDAIQDEKKGLVYSTRILLSRHTLGVDGRLLPLTAGLAVNVG 420 F+YTKYGT+ RV VSRDAI+DEKKGL+YS + L + ++ VDGR + L+ G++ V Sbjct: 361 TFEYTKYGTIPARVTHVSRDAIEDEKKGLIYSVMVTLDKTSIDVDGRKIKLSPGMSTTVE 420 Query: 421 IRTGSRRVIEYALSPLLRHQKEALHER 447 I+TG+RRVIEY LSPL++H +E+L ER Sbjct: 421 IKTGTRRVIEYVLSPLIQHARESLRER 447 >XF2398 [M] COG0845 Membrane-fusion protein Xfa Xylella fastidiosa 9a5c Length = 473 Score = 308 bits (788), Expect = 2e-83, Method: Compositional matrix adjust. Identities = 184/474 (38%), Positives = 275/474 (58%), Gaps = 30/474 (6%) Query: 3 LHHRSQAWMALLLRYRRRFLQAWRDR-HLQPEGFFNQQEAEFLPAALSLQEAPDSPSLRW 61 + H Q W L RY F AW R L+P E FLPA L L E P SP+ RW Sbjct: 1 MKHMLQGWRDFLSRYLHVFRAAWSIRAQLEPP-HRTADERTFLPAHLELTETPVSPTARW 59 Query: 62 TARLLVAMVLLALAWSLIGQIDIVVSANGKVIPSARTKTIASVEVASVRAILVREGQFVQ 121 + R+++A ++AL W+ G+I+IV A GK++ +RTK + +E A VR IL+R+G+ V+ Sbjct: 60 SMRIIIACFIVALLWACFGKIEIVAVAPGKIVVDSRTKVLQPLETAVVRRILIRDGEKVK 119 Query: 122 AGQVLLELDASSSDAERDKAADAVAQARLQAARAAAMMQAVQQLRAPELQDVADV----- 176 A Q L+ELDA++++AE +A DA+ A L A R A+ A+++ + P+L A + Sbjct: 120 AHQALIELDATATNAEYTQAEDALLNATLTALRLRALSTALERGQTPQLTHSATIPADRI 179 Query: 177 ------SLAQWESV---RRQLQGQYQDFRARLDRFDDEIVRYTKALRLASQRATDYQELM 227 +L+Q+ + R LQ RA L D I T++ R++ R+ DY L+ Sbjct: 180 AAEQALTLSQFNAFQAKRHNLQATIAQRRAELRTAQDTIEPLTESARISKMRSADYAILL 239 Query: 228 ADHTVSRHAWLEKEQARVDLQGQLTDARNQ----RAALLAQTQ----------KEAHDSR 273 D V RH +L +EQ R+ + L RN+ R+AL A + ++ D Sbjct: 240 KDQYVGRHDYLLREQERITAERDLATQRNRIQEIRSALSAAQEELSVLQADFRQQTLDDL 299 Query: 274 LEAEKIIEAAQKDQRRAQERSKLLHLRAPVSGTVQQLNVHTIGGVVPAAQPLMQIVPEDG 333 +A++ I +A++R++L+ LR+PV G VQQL +HT+GGVV AQ L+ +VP Sbjct: 300 RKADEQIGQLTPQLAKAKQRNRLMTLRSPVEGIVQQLAIHTVGGVVTPAQQLLAVVPVQE 359 Query: 334 EIEVEAWLDNKDVGFVEVGQEVEVKVDAFDYTKYGTVAGRVVQVSRDAIQDEKKGLVYST 393 +EVEA + NKD+GF+ Q V VK+++F YT+YG + G+VV +S DA QDEK GLV+ Sbjct: 360 TLEVEATVLNKDIGFLRPEQRVTVKIESFPYTRYGYLTGKVVSISHDAAQDEKLGLVFPV 419 Query: 394 RILLSRHTLGVDGRLLPLTAGLAVNVGIRTGSRRVIEYALSPLLRHQKEALHER 447 RI L TL +DG + ++AG+A++ I+TG R VI+Y LSPL ++ EAL ER Sbjct: 420 RIRLDNTTLTIDGTQIRMSAGMALSAEIKTGKRTVIDYLLSPLKQYTDEALRER 473 >NMB1738 [M] COG0845 Membrane-fusion protein Nme Neisseria meningitidis MC58 Length = 475 Score = 273 bits (699), Expect = 5e-73, Method: Compositional matrix adjust. Identities = 169/476 (35%), Positives = 268/476 (56%), Gaps = 40/476 (8%) Query: 10 WMALLLRYRRRFLQAWRD-----RHLQPEGFFNQQEAEFLPAALSLQEAPDSPSLRWTAR 64 + + L + R++ WR+ L+P +++A FLPA L L + P S + +W AR Sbjct: 2 FFSALKSFLSRYITVWRNVWAVRDQLKPPKRTAEEQA-FLPAHLELTDTPVSAAPKWAAR 60 Query: 65 LLVAMVLLALAWSLIGQIDIVVSANGKVIPSARTKTIASVEVASVRAILVREGQFVQAGQ 124 ++A LLAL WS G+IDIV +A+GK + R+KTI +E A V+A+ VR+GQ V+ G+ Sbjct: 61 FIMAFALLALLWSWFGKIDIVAAASGKTVSGGRSKTIQPLETAVVKAVHVRDGQHVKQGE 120 Query: 125 VLLELDASSSDAERDKAADAVAQARLQAARAAAMMQAVQ----------QLRAPELQDVA 174 L EL+A +D++ ++ A+ A+L R A++ A++ Q R+ L D A Sbjct: 121 TLAELEAVGTDSDVVQSEQALQAAQLSKLRYEAVLAALESRTVPHIDMAQARSLGLSD-A 179 Query: 175 DVSLAQ---------WESVRRQLQGQYQDFRARLDRFDDEIVRYTKALRLASQRATDYQE 225 DV AQ W + QLQ + +A L + + + Q+ DY+ Sbjct: 180 DVQSAQVLAQHQYQAWAAQDAQLQSALRGHQAELQSAKAQEQKLVSVGAIEQQKTADYRR 239 Query: 226 LMADHTVSRHAWLEKEQARVDLQGQLTDARNQR---AALLAQTQ-----------KEAHD 271 L AD+ +S HA+LE++ V L R Q A +AQ + ++ D Sbjct: 240 LRADNFISEHAFLEQQSKSVSNWNDLESTRGQMRQIQAAIAQAEQNRVLNTQNLKRDTLD 299 Query: 272 SRLEAEKIIEAAQKDQRRAQERSKLLHLRAPVSGTVQQLNVHTIGGVVPAAQPLMQIVPE 331 + +A + I+ + +A++R +L+ +++P GTVQ+L +T+GGVV AAQ +M I P+ Sbjct: 300 ALRQANEQIDQYRGQTDKAKQRQQLMTIQSPADGTVQELATYTVGGVVQAAQKMMVIAPD 359 Query: 332 DGEIEVEAWLDNKDVGFVEVGQEVEVKVDAFDYTKYGTVAGRVVQVSRDAIQDEKKGLVY 391 D +++VE + NKD+GFVE GQ+ VK+++F YT+YG + G+V VS DA+ E+ GLVY Sbjct: 360 DDKMDVEVLVLNKDIGFVEQGQDAVVKIESFPYTRYGYLTGKVKSVSHDAVSHEQLGLVY 419 Query: 392 STRILLSRHTLGVDGRLLPLTAGLAVNVGIRTGSRRVIEYALSPLLRHQKEALHER 447 + + L +HTL +DG+ + LTAG+ V I+TG RRV++Y LSPL E+ ER Sbjct: 420 TAVVSLDKHTLNIDGKAVNLTAGMNVTAEIKTGKRRVLDYLLSPLQTKLDESFRER 475 >NMA1996 [M] COG0845 Membrane-fusion protein NmA Neisseria meningitidis Z2491 Length = 454 Score = 235 bits (599), Expect = 2e-61, Method: Compositional matrix adjust. Identities = 148/436 (33%), Positives = 242/436 (55%), Gaps = 40/436 (9%) Query: 10 WMALLLRYRRRFLQAWRD-----RHLQPEGFFNQQEAEFLPAALSLQEAPDSPSLRWTAR 64 + + L + R++ WR+ L+P +++A FLPA L L + P S + +W AR Sbjct: 2 FFSALKSFLSRYITVWRNVWAVRDQLEPPKRTAEEQA-FLPAHLELTDTPVSAAPKWAAR 60 Query: 65 LLVAMVLLALAWSLIGQIDIVVSANGKVIPSARTKTIASVEVASVRAILVREGQFVQAGQ 124 ++A LLAL WS G+IDIV +A+GK + R+KTI +E V+A+ VR+GQ V+ G+ Sbjct: 61 FIMAFALLALLWSWFGKIDIVAAASGKTVSGGRSKTIQPLETVVVKAVHVRDGQHVKQGE 120 Query: 125 VLLELDASSSDAERDKAADAVAQARLQAARAAAMMQAVQ----------QLRAPELQDVA 174 L EL+A +D++ ++ A+ A+L R A++ A++ Q R+ L D A Sbjct: 121 TLAELEAVGTDSDVVQSEQALQAAQLSKLRYEAVLAALESRTVPHIDMAQARSLGLSD-A 179 Query: 175 DVSLAQ---------WESVRRQLQGQYQDFRARLDRFDDEIVRYTKALRLASQRATDYQE 225 DV AQ W + QLQ + +A L + + + Q+ DY+ Sbjct: 180 DVQSAQVLAQHQYQAWAAQDAQLQSALRGHQAELQSAKAQEQKLVSVGAIEQQKTADYRR 239 Query: 226 LMADHTVSRHAWLEKEQARVDLQGQLTDARNQR---AALLAQTQ-----------KEAHD 271 L AD+ +S HA+LE++ V L R Q A +AQ + ++ D Sbjct: 240 LRADNFISEHAFLEQQSKSVSNWNDLESTRGQMRQIQAAIAQAEQNRVLNTQNLKRDTLD 299 Query: 272 SRLEAEKIIEAAQKDQRRAQERSKLLHLRAPVSGTVQQLNVHTIGGVVPAAQPLMQIVPE 331 + +A + I+ + +A++R +L+ +++P GTVQ+L +T+GGVV AAQ +M + P+ Sbjct: 300 ALRQANEQIDQYRGQTDKAKQRQQLMTIQSPADGTVQELATYTVGGVVQAAQKMMVVAPD 359 Query: 332 DGEIEVEAWLDNKDVGFVEVGQEVEVKVDAFDYTKYGTVAGRVVQVSRDAIQDEKKGLVY 391 D +++VE + NKD+GFVE GQ+ VK+++F YT+YG + G+V VS DA+ E+ GLVY Sbjct: 360 DDKMDVEVLVLNKDIGFVEQGQDAVVKIESFPYTRYGYLTGKVKSVSHDAVSHEQLGLVY 419 Query: 392 STRILLSRHTLGVDGR 407 + + L +HTL +DG+ Sbjct: 420 TAVVSLDKHTLNIDGK 435 >VC1447 [M] COG0845 Membrane-fusion protein Vch Vibrio cholerae Length = 467 Score = 202 bits (514), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 150/452 (33%), Positives = 232/452 (51%), Gaps = 45/452 (9%) Query: 35 FFNQQEA--------EFLPAALSLQEAPDSPSLRWTARLLVAMVLLALAWSLIGQIDIVV 86 FF Q+ EFLPA L+L + P SP R TA L VL AL W+ G++D+ Sbjct: 22 FFGQKSPHQPTEHHYEFLPAHLALAQRPPSPFARVTALTLSLGVLAALLWAYWGKLDVQA 81 Query: 87 SANGKVIPSARTKTIASVEVASVRAILVREGQFVQAGQVLLELDASSSDAERDKAADAVA 146 +A G+++ S R++ I S E + + +I VR+GQ V+ G LL LD + + + V+ Sbjct: 82 TATGRLVVSGRSQVIQSYEQSRLLSIHVRDGQRVEKGAPLLTLDTLGVNQDITR---LVS 138 Query: 147 QARLQAA---RAAAMMQAVQQLRAPELQDVADVSLAQWESVRRQLQGQYQDFRARLDRFD 203 QA Q R ++ P + Q + + +F + L Sbjct: 139 QAEFQTNELIRYRTLLNDQLLTHDPMF---TALPAEQQALIHENYLSEKNEFDSTLASIT 195 Query: 204 DE--IVRYTKALRLA------------SQRATDYQELMADHTVSRHAWLEKEQARVDLQG 249 E + R ++A R + SQR ++L + +LE+E+ ++ Q Sbjct: 196 AEMKVNRTSQAARQSDIHALLQLTENISQRLAARKKLNQVKVIGHVEYLEQEKELLEAQR 255 Query: 250 QLTDARNQRAAL--------------LAQTQKEAHDSRLEAEKIIEAAQKDQRRAQERSK 295 Q+ R + L AQ Q+E + R +A + + ++ + +ER + Sbjct: 256 QVAQQRAELEVLKSQYESLEERLTGFKAQKQREWLEKRRQARLQLASLNQELSKVREREQ 315 Query: 296 LLHLRAPVSGTVQQLNVHTIGGVVPAAQPLMQIVPEDGEIEVEAWLDNKDVGFVEVGQEV 355 L +R+PV GTVQQL+V+T+G V+ AQ LM IVPE+ + E + NKDVGFV GQ V Sbjct: 316 LEIIRSPVDGTVQQLSVYTLGAVLQPAQNLMIIVPENRVQQAEVQILNKDVGFVYPGQSV 375 Query: 356 EVKVDAFDYTKYGTVAGRVVQVSRDAIQDEKKGLVYSTRILLSRHTLGVDGRLLPLTAGL 415 VKVDAF YT+YGT+ ++ +SRD+ DE+ GLV+ +I L + + +DG+ + LT G+ Sbjct: 376 TVKVDAFPYTRYGTIDAELLSISRDSTTDEQLGLVFPAQIQLKTNHIMIDGQTVELTPGM 435 Query: 416 AVNVGIRTGSRRVIEYALSPLLRHQKEALHER 447 +V I+T RRVI+Y LSP+ +Q EAL ER Sbjct: 436 SVVAEIKTDKRRVIDYLLSPIQEYQAEALRER 467