BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0001.2818.p         (535 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

mrr [V] COG1715 Restriction endonuclease Eco Escherichia coli K12      61   7e-09
STM4527 Non COG                                                        60   1e-08
alr7132 [V] COG1715 Restriction endonuclease Nos Nostoc sp. PCC ...    57   1e-07
RSc3416_1 Non COG                                                      52   2e-06
Rv2528c [V] COG1715 Restriction endonuclease Mtu Mycobacterium t...    52   3e-06

>mrr [V] COG1715 Restriction endonuclease Eco Escherichia coli K12
          Length = 304

 Score = 60.8 bits (146), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 38/131 (29%), Positives = 73/131 (55%), Gaps = 6/131 (4%)

Query: 409 NLLDLTPGEFEILVSNLFGKMGL---ETKLTRSSRDGGVDAVAYDTRPILG-GKVVIQAK 464
           NLL ++P  FE++V ++  ++G       L R    G        +   LG  KV +QAK
Sbjct: 162 NLLQVSPSRFEVIVLDVLHRLGYGGHRDDLQRVGGTGDGGIDGVISLDKLGLEKVYVQAK 221

Query: 465 RYKDTVGVSAVRDLFGTMMNEGANKGILVCTSGYGTDAYNFCKD-KPIELIDGGGLLYLL 523
           R+++TVG   ++  +G +  + A +G+ + TSG+ + A +F +  + + L+DG  L++L+
Sbjct: 222 RWQNTVGRPELQAFYGALAGQKAKRGVFITTSGFTSQARDFAQSVEGMVLVDGERLVHLM 281

Query: 524 REH-AGIEARI 533
            E+  G+ +R+
Sbjct: 282 IENEVGVSSRL 292


>STM4527 Non COG
          Length = 304

 Score = 60.1 bits (144), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 39/131 (29%), Positives = 71/131 (54%), Gaps = 6/131 (4%)

Query: 409 NLLDLTPGEFEILVSNLFGKMGL---ETKLTRSSRDGGVDAVAYDTRPILG-GKVVIQAK 464
           NLL ++P  FE++V ++  ++G       L R    G        +   LG  KV +QAK
Sbjct: 162 NLLQVSPARFEVIVLDVLHRLGYGGHRGDLQRVGGTGDGGIDGIISLDKLGLEKVYVQAK 221

Query: 465 RYKDTVGVSAVRDLFGTMMNEGANKGILVCTSGYGTDAYNFC-KDKPIELIDGGGLLYLL 523
           R+K TVG + VR  +G +  +   +G+ + TSG+   A ++  K + + L+DG  L++L+
Sbjct: 222 RWKGTVGSAEVRGFYGALPEQKVKRGVFITTSGFTAHARDYANKVEGLVLVDGDRLVHLM 281

Query: 524 REH-AGIEARI 533
            ++  G+ +R+
Sbjct: 282 IDNDIGVSSRL 292


>alr7132 [V] COG1715 Restriction endonuclease Nos Nostoc sp. PCC 7120
          Length = 305

 Score = 57.0 bits (136), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 42/122 (34%), Positives = 63/122 (51%), Gaps = 11/122 (9%)

Query: 414 TPGEFEILVSNLFGKMGL------ETKLTRSSRDGGVDAVAYDTRPILGGKVV-IQAKRY 466
           +P  FE LV +L  KMG         K    S DGG+D +  + R  LG  V+ IQAKR+
Sbjct: 163 SPAFFEKLVVDLLVKMGYGGTRKDAGKTVGRSGDGGIDGIINEDR--LGLDVIYIQAKRW 220

Query: 467 KDTVGVSAVRDLFGTMMNEGANKGILVCTSGYGTDAYNFCK--DKPIELIDGGGLLYLLR 524
           +++VG   ++   G +    A KG+ + TS +  +A ++    D  I LIDG  L  L+ 
Sbjct: 221 ENSVGRPEIQKFAGALQGFRAKKGVFITTSTFTNEAKDYVSRIDSKIVLIDGEMLTQLMI 280

Query: 525 EH 526
           E+
Sbjct: 281 EN 282


>RSc3416_1 Non COG
          Length = 243

 Score = 52.4 bits (124), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 36/111 (32%), Positives = 56/111 (50%), Gaps = 7/111 (6%)

Query: 417 EFEILVSNLFGKMGLETKLTRSSRDGGVDAVAYDTRPILGGKV-VIQAKRYKD-TVGVSA 474
           E E LV  +F         T    DGG D   +      GG++ ++Q K+++   V + A
Sbjct: 114 ELERLVGQVFRMHCYTVTETGDGADGGADLQLHK-----GGELYLVQCKQWQAYKVSIDA 168

Query: 475 VRDLFGTMMNEGANKGILVCTSGYGTDAYNFCKDKPIELIDGGGLLYLLRE 525
           VR+L G M+ +GA  G +V +  +  DA  F K K I L+DG  L  L+++
Sbjct: 169 VRELHGLMVAQGAAGGFVVTSGVFTADARAFAKGKHIALVDGVTLTTLIKQ 219


>Rv2528c [V] COG1715 Restriction endonuclease Mtu Mycobacterium tuberculosis
           H37Rv
          Length = 306

 Score = 52.0 bits (123), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 40/130 (30%), Positives = 64/130 (49%), Gaps = 10/130 (7%)

Query: 411 LDLTPGEFEILVSNLFGKMGL----ETKLTRSSRDGGVDAVAYDTRPILGGKVVIQAKRY 466
           L L+P  FE LV  L   MG       + T +S D G+D +     P+   ++ +QAKRY
Sbjct: 161 LTLSPTGFEDLVIRLLEAMGYGRAGAVERTSASGDAGIDGI-ISQDPLGLDRIYVQAKRY 219

Query: 467 --KDTVGVSAVRDLFGTMMNEGANKGILVCTSGYGTDAYNFCK--DKPIELIDGGGLLYL 522
               T+G   + +  G ++ +  ++G+ + TS +   A    +  +  IELIDG  L  L
Sbjct: 220 AVDQTIGRPKIHEFAGALLGKQGDRGVYITTSSFSRGAREEAERINARIELIDGARLAEL 279

Query: 523 L-REHAGIEA 531
           L R   G++A
Sbjct: 280 LVRYRVGVQA 289