BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.2802.p (281 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BMEII1074 [G] COG2301 Citrate lyase beta subunit Bme Brucella me... 219 8e-57 PA0883 [G] COG2301 Citrate lyase beta subunit Pae Pseudomonas ae... 168 2e-41 VNG0627G [G] COG2301 Citrate lyase beta subunit Hbs Halobacteriu... 144 3e-34 DR2206 [G] COG2301 Citrate lyase beta subunit Dra Deinococcus ra... 129 9e-30 Rv3075c [G] COG2301 Citrate lyase beta subunit Mtu Mycobacterium... 127 3e-29 >BMEII1074 [G] COG2301 Citrate lyase beta subunit Bme Brucella melitensis Length = 274 Score = 219 bits (557), Expect = 8e-57, Method: Compositional matrix adjust. Identities = 131/260 (50%), Positives = 161/260 (61%), Gaps = 12/260 (4%) Query: 14 LFVPANRPERYAKALQSGADAVIVDLEDAVAPSQKEAARAMLAHWLQEQAAQPRIWVRIN 73 LFVPA+RP+R++KA SG D VI+DLEDAVAP K+AARA L + + VRIN Sbjct: 11 LFVPADRPDRFSKAAASGTDCVILDLEDAVAPKAKDAARAALDTSFTDLP----VMVRIN 66 Query: 74 AADTVWHQQDLLTFSAPSLAGIVLPKAEDAATVASVAAHLGAGCRLIALIESAAGLAAMR 133 T WH+ D+ + +AG++LPKAE A + + A L LIAL+E+A GLA R Sbjct: 67 PHGTPWHEADMAAVARLDVAGVILPKAETAERIEAAARMLD--LPLIALVETARGLANAR 124 Query: 134 QIAAVPGVQRLAFGSIDAQLDLRMQCGPQEEELMPLRVEMVMASRLAGIAPPIDGVTTDF 193 IAA GV RLAFGSID DL C E L+P RVE+VMASRLAGIA PIDGVT F Sbjct: 125 SIAAASGVVRLAFGSIDFCADL--ACAHMREILLPARVELVMASRLAGIAAPIDGVTPGF 182 Query: 194 NDDALLARMVQQARRLGFGAKLCIHPRQVDGVRHGFMPSEQELAWAEEVMAAVRASDGGA 253 ND + + AR LG KLCIHPRQ+ V F S+QE+ WA V+ AS GA Sbjct: 183 NDPVMCHQDAAHARALGMMGKLCIHPRQISEVLRAFAWSDQEIDWARRVL----ASGEGA 238 Query: 254 ISFKGKMIDKPVILQAEQFL 273 IS G M+D+PV ++A L Sbjct: 239 ISIDGMMVDEPVRIRARTIL 258 >PA0883 [G] COG2301 Citrate lyase beta subunit Pae Pseudomonas aeruginosa Length = 275 Score = 168 bits (425), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 125/272 (45%), Positives = 161/272 (59%), Gaps = 7/272 (2%) Query: 9 IASSYLFVPANRPERYAKALQSGADAVIVDLEDAVAPSQKEAARAMLAHWLQEQAAQPRI 68 I S LFVPA RPER KAL SGAD VIVDLEDAV K ARA L +L + + R+ Sbjct: 5 IVRSALFVPATRPERIPKALASGADRVIVDLEDAVEEGLKVEARANLRRFLVD-TPEARV 63 Query: 69 WVRINAADTVWHQQDL-LTFSAPSLAGIVLPKAEDAATVASVAAHLGAGCRLIALIESAA 127 VRINAA+ H DL L + G++LPK E AA V A + +G + ++ESA Sbjct: 64 LVRINAAEHPGHADDLALCRDHAGVIGLLLPKVESAAQVRHAA--VASGKPVWPIVESAR 121 Query: 128 GLAAMRQIAAVPGVQRLAFGSIDAQLDLRMQCGPQ--EEELMPLRVEMVMASRLAGIAPP 185 GLAA+ +IAA GV+RL+FGS+D LDL + G E+ L R +++ +RLAG+APP Sbjct: 122 GLAALGEIAAAAGVERLSFGSLDLALDLDLNSGSNAAEQILGHARYALLLQTRLAGLAPP 181 Query: 186 IDGVTTDFNDDALLARMVQQARRLGFGAKLCIHPRQVDGVRHGFMPSEQELAWAEEVMAA 245 +DGV + A L V+ AR +GFG LCIHP QV+ + MPS EL WA V A Sbjct: 182 LDGVYPAIQNRAGLVEAVRFARDMGFGGLLCIHPSQVEPIHQTLMPSPAELEWARRV-AE 240 Query: 246 VRASDGGAISFKGKMIDKPVILQAEQFLRVAG 277 AS G G+M+D PV+ +A + L AG Sbjct: 241 AGASGAGVFVVDGEMVDAPVLGRARRLLERAG 272 >VNG0627G [G] COG2301 Citrate lyase beta subunit Hbs Halobacterium sp. NRC-1 Length = 303 Score = 144 bits (362), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 98/268 (36%), Positives = 139/268 (51%), Gaps = 6/268 (2%) Query: 12 SYLFVPANRPERYAKALQSGADAVIVDLEDAVAPSQKEAARAMLAHWLQEQAAQP--RIW 69 S LF P ++P KA +GAD V+ DLEDAVAP++K AR ++ L P + Sbjct: 30 SVLFSPGDQPSLMRKAPTTGADVVVFDLEDAVAPARKGDARRAVSDLLTAADFDPDCEVC 89 Query: 70 VRINAADTVWHQQDLLTFSAPSLAGIVLPK---AEDAATVASVAAHLGAGCRLIALIESA 126 VR+N + S +V+PK A+D ATV S+ A A ++AL+ESA Sbjct: 90 VRVNPVGSGAGDDVDAVLSGGGFDSVVVPKVTDADDVATVDSLLAEHDATSPVLALVESA 149 Query: 127 AGLAAMRQIAAVPGVQRLAFGSIDAQLDLRMQCGPQEEELMPLRVEMVMASRLAGIAPPI 186 AG+ +IAA L FG+ D D+ + E++ R +V+A+ AG+ I Sbjct: 150 AGVLNAHEIAAAGPTDALVFGAEDLSADIGATRTDEGTEVLYARERVVLAASAAGV-DAI 208 Query: 187 DGVTTDFNDDALLARMVQQARRLGFGAKLCIHPRQVDGVRHGFMPSEQELAWAEEVMAAV 246 D V T D + +A + A LGF KL IHP QVD + + P+E + AWA V+ A Sbjct: 209 DTVHTAIEDPSAVAADARFAADLGFDGKLAIHPAQVDPINDAYTPTEADTAWATRVLDAA 268 Query: 247 RASDGGAISFKGKMIDKPVILQAEQFLR 274 SD G G+MID P+I QAE+ +R Sbjct: 269 ADSDAGVFRVDGEMIDAPLIAQAERIMR 296 >DR2206 [G] COG2301 Citrate lyase beta subunit Dra Deinococcus radiodurans Length = 274 Score = 129 bits (323), Expect = 9e-30, Method: Compositional matrix adjust. Identities = 103/283 (36%), Positives = 142/283 (50%), Gaps = 15/283 (5%) Query: 1 MSTKPDWAIASSYLFVPANRPERYAKALQSGADAVIVDLEDAVAPSQKEAARAMLAHWLQ 60 MS KP S L+VP ++P KA GADAVI+DLEDAVAP K AARA + L Sbjct: 1 MSAKP----LRSLLYVPGDKPRAIEKARTLGADAVILDLEDAVAPEHKGAARANVQAALA 56 Query: 61 EQAAQPRIWVRINAADTVWHQQDLLTFSAPSLAGIVLPKAEDAATVASVAAHLGAGCRLI 120 E P + VR+N T W D + G+VLPK E+ +V + HL L Sbjct: 57 ESWPCP-VLVRVNGLGTEWEHADREMALLAGVDGLVLPKVEEGRSVTEL--HL--RVPLW 111 Query: 121 ALIESAAGLAAMRQIAAVPGVQRLAFGSIDAQLDLRMQCGPQEEELMPLRVEMVMASRLA 180 A+IE+ G+ IAA PGV L G+ D LR Q P+ L+ +V+A+R A Sbjct: 112 AMIETPRGVLNAPAIAAAPGVAGLLVGANDLARALRTQPQPERLPLLHALSAVVLAARAA 171 Query: 181 GIAPPIDGVTTDFNDDALLARMVQQARRLGFGAKLCIHPRQVDGVRHGFMPSEQELAWAE 240 G PID V D D A R +Q R LGF K IHP QV F S+++ A Sbjct: 172 GKL-PIDAVYNDVRDPAGFVRECEQGRTLGFAGKTVIHPDQVAAANSAFGVSDEQAQAAR 230 Query: 241 EVMA---AVRASDGGAISFKGKMIDKPVILQAEQFLRV--AGR 278 +++A A R +++G ++++ + +A + L + AGR Sbjct: 231 DLLAAWDAARQEGKSVATWRGALVEQMHVDEAHEQLALWEAGR 273 >Rv3075c [G] COG2301 Citrate lyase beta subunit Mtu Mycobacterium tuberculosis H37Rv Length = 307 Score = 127 bits (319), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 95/274 (34%), Positives = 128/274 (46%), Gaps = 11/274 (4%) Query: 3 TKPDWAIASSYLFVPANRPERYAKALQSGADAVIVDLEDAVAPSQKEAARAMLAHWLQEQ 62 ++ D +A S+L V +R+ A S AD V++D+EDAVAP K AAR W + Sbjct: 19 SRIDPVLARSWLLVNGAHGDRFESAAHSRADIVVLDIEDAVAPKDKHAARDNAVRWFGDG 78 Query: 63 AAQPRIWVRINAADTVWHQQDLLTFSAPSLAGIVLPKAEDAATVASVAAHLGAGCRLIAL 122 A WVRIN T W DL + + G++L E V A L ++AL Sbjct: 79 NAD---WVRINGFGTPWWADDLAMLADSPVGGVMLAMVESVDHVTETAKRL-PNVPIVAL 134 Query: 123 IESAAGLAAMRQIAAVPGVQRLAFGSIDAQLDLRMQCGPQEEELMPLRVEMVMASRLAGI 182 +E+A GL + +IAA G RLAFG D + D G L R +A+R AG+ Sbjct: 135 VETARGLERINEIAAAKGTFRLAFGIGDFRRDTGF--GEDPATLAYARSRFTIAARAAGL 192 Query: 183 APPIDGVTTDFNDDALLARMVQQARRLGFGAKLCIHPRQVDGVRHGFMPSEQELAWAEEV 242 IDG T N L+ A G K+C+ P Q V G PS+ E+ WA+E Sbjct: 193 PSAIDGPTIGSNALKLIEATAVSA-EFGMTGKICLSPDQCPVVNEGLSPSQDEIVWAKEF 251 Query: 243 MAAVRASDGGAISFKGKMIDKPVILQAEQFLRVA 276 A A DGG I D P I +A + L +A Sbjct: 252 FAEF-ARDGGEIR---NGSDLPRIARATKILDLA 281