BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.2762.p (424 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp1177 [GEPR] COG0477 Permeases of the major facilitator superf... 422 e-118 CAP0049 [GEPR] COG0477 Permeases of the major facilitator superf... 409 e-114 PA4622 [GEPR] COG0477 Permeases of the major facilitator superfa... 403 e-112 SMc03237 [GEPR] COG0477 Permeases of the major facilitator super... 333 6e-91 mlr4214 [GEPR] COG0477 Permeases of the major facilitator superf... 328 1e-89 >RSp1177 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 424 Score = 422 bits (1086), Expect = e-118, Method: Compositional matrix adjust. Identities = 247/394 (62%), Positives = 300/394 (76%), Gaps = 5/394 (1%) Query: 26 FKLFWCASVASTIALQMQIVAVGWQVYQLTHSAFDLGIVGLVQFIPSLILVFVVGHVADR 85 F+LFW A +++T A QM VAVGWQ+Y LT SA+ LG+VGL QF+PS++LV GH+ADR Sbjct: 27 FRLFWLARLSTTFAYQMFGVAVGWQIYDLTRSAYVLGLVGLAQFLPSVVLVLASGHIADR 86 Query: 86 FDRRNVARISALVEASAAATLALGSLGGWLNREMIFVIVAVIGAGRAFSKPTMSALLPSL 145 +DRR V RI +EA AA LA +L G + + IFV V VIGA RAF PT+ ALLPSL Sbjct: 87 YDRRRVVRICQAIEALVAAMLAAATLTGHASIQPIFVFVVVIGAMRAFETPTLQALLPSL 146 Query: 146 MSPRALPGAVAGSASATQFAIIIGPALGGFLYVAGPAVVYASSCALFALCSLLLWLIRRP 205 + P ALP AVA S+SA Q II+GPA+GGFLYVAG VVYA++ LF L +L+ +R Sbjct: 147 VPPAALPRAVALSSSAGQTGIILGPAVGGFLYVAGAPVVYATAAGLFVLAHVLVACVR-- 204 Query: 206 PQADLAGATKPTGASLSSVFAGLAFIRSKPAIFGAISLDMFAVLLGGATALLPVYANDIL 265 A ++P SL S+FAG+AFI+ +P + GAISLD+FAVLLGGATALLP+YA DIL Sbjct: 205 -TGRAAPVSRPV--SLESLFAGIAFIKGRPVVLGAISLDLFAVLLGGATALLPIYARDIL 261 Query: 266 HTGAVGLGLLRSAPAAGALAVALLLARRPLAGRVGRTMFIAVGVFGLATIVFGLSRSFPL 325 TGA GLGLLRSAPA GALA+A+ LA RPL VGR MF AV +FGLAT+VFG+SR PL Sbjct: 262 GTGAWGLGLLRSAPAIGALAMAIFLAHRPLERHVGRVMFAAVALFGLATMVFGVSRWLPL 321 Query: 326 SLAALAVLGAADMISVVVRSSFVQLETPDAMRGRVSAVNSVFIGTSNQLGEFESGLTAAW 385 S+ AL VLGA DM+SVV+R+S VQL+TPDAMRGRVSAVNSVF+G SNQLGEFESG+ A Sbjct: 322 SMLALVVLGAGDMVSVVIRTSLVQLDTPDAMRGRVSAVNSVFVGASNQLGEFESGMVAGM 381 Query: 386 FGAVPAVLIGGIGTLLIVLLWIRLFPALYQVDRL 419 G VP+V++GG+GTLL+V LW+RLFPAL DRL Sbjct: 382 LGPVPSVVLGGLGTLLVVALWMRLFPALTHRDRL 415 >CAP0049 [GEPR] COG0477 Permeases of the major facilitator superfamily Cac Clostridium acetobutylicum Length = 408 Score = 409 bits (1052), Expect = e-114, Method: Compositional matrix adjust. Identities = 206/394 (52%), Positives = 276/394 (70%), Gaps = 5/394 (1%) Query: 31 CASVASTIALQMQIVAVGWQVYQLTHSAFDLGIVGLVQFIPSLILVFVVGHVADRFDRRN 90 A V+S A QM VA+GWQ+Y LTHSAF LG++GLVQF+P L+L VGH++DR+DRR Sbjct: 20 TARVSSNFAYQMLTVAIGWQMYSLTHSAFYLGLIGLVQFLPMLVLSLFVGHISDRYDRRK 79 Query: 91 VARISALVEASAAATLALGSLGGWLNREMIFVIVAVIGAGRAFSKPTMSALLPSLMSPRA 150 + IS LV+ A LA G+ GW+ +E ++V I +F P M ALLP+++ + Sbjct: 80 IVSISQLVQGICIALLAFGNYNGWITKESFLIMVFFIALAHSFEGPPMQALLPNIVERKI 139 Query: 151 LPGAVAGSASATQFAIIIGPALGGFLYVAGPAVVYASSCALFALCSLLLWLIRRPPQADL 210 P A A +SA+QFA+I+GP G LY G +++Y+ + L L S+L+ I + Sbjct: 140 FPKASALVSSASQFAVIVGPGFAGILYSFGASLIYSITAGLLILASVLIIQIHVNKEER- 198 Query: 211 AGATKPTGASLSSVFAGLAFIRSKPAIFGAISLDMFAVLLGGATALLPVYANDILHTGAV 270 KP +L S FAG+ FI+S+P I GAISLD+FAVL GGATALLP+YA+ IL G+ Sbjct: 199 ----KPDPVNLKSFFAGITFIKSRPIILGAISLDLFAVLFGGATALLPIYASSILKIGSF 254 Query: 271 GLGLLRSAPAAGALAVALLLARRPLAGRVGRTMFIAVGVFGLATIVFGLSRSFPLSLAAL 330 GLG+LRSAPA GAL ++ LL R+PL VG+ MF AV FGL+TI+F +S+S +S AL Sbjct: 255 GLGVLRSAPAVGALLMSALLTRKPLKRNVGKIMFTAVVCFGLSTIIFAISKSVIVSFLAL 314 Query: 331 AVLGAADMISVVVRSSFVQLETPDAMRGRVSAVNSVFIGTSNQLGEFESGLTAAWFGAVP 390 VLGA+D+ISVV+RS+ VQLETPD MRGRVS+VN +FIGTSNQLGEFESG+TA+ G VP Sbjct: 315 FVLGASDVISVVIRSTLVQLETPDNMRGRVSSVNMIFIGTSNQLGEFESGITASLLGTVP 374 Query: 391 AVLIGGIGTLLIVLLWIRLFPALYQVDRLAARRS 424 A L+GG+GT+L+VL+W +LF +L+ VD ++ Sbjct: 375 AALLGGVGTILVVLIWRKLFSSLFTVDSFEGSKN 408 >PA4622 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 403 Score = 403 bits (1036), Expect = e-112, Method: Compositional matrix adjust. Identities = 231/408 (56%), Positives = 281/408 (68%), Gaps = 9/408 (2%) Query: 14 SEQQLPLRHHTPFKLFWCASVASTIALQMQIVAVGWQVYQLTHSAFDLGIVGLVQFIPSL 73 S Q L H PF FW A V + QM VA+GW +Y+LT + DLG+VGLV+F+P + Sbjct: 2 SSQPSSLLRHRPFLAFWLARVCTASGFQMLTVAIGWHIYELTGNVLDLGLVGLVEFLPRV 61 Query: 74 ILVFVVGHVADRFDRRNVARISALVEASAAATLALGSLGGWLNREMIFVIVAVIGAGRAF 133 + + GHVADR+DRR +A + +A A L LG+ G + R MIFV+ +G RAF Sbjct: 62 LFMLHTGHVADRYDRRRIAALCQAGQALVAVALVLGAASGEITRNMIFVLAFALGTARAF 121 Query: 134 SKPTMSALLPSLMSPRALPGAVAGSASATQFAIIIGPALGGFLYVAGPAVVYASSCALFA 193 PT ALLP+L+ P AVA SASA Q A I PALGG LY G + VY + L+ Sbjct: 122 EMPTTQALLPNLVPAGLFPRAVAASASAMQAATIAAPALGGLLYAFGASWVYVPTATLYV 181 Query: 194 L-CSLLLWL-IRRPPQADLAGATKPTGASLSSVFAGLAFIRSKPAIFGAISLDMFAVLLG 251 L C L L L +R P A+L S+ AG+ FIRS+P IFGAISLD+FAVLLG Sbjct: 182 LACVLTLSLPVRNQPLTQ-------GKATLDSLLAGIRFIRSRPDIFGAISLDLFAVLLG 234 Query: 252 GATALLPVYANDILHTGAVGLGLLRSAPAAGALAVALLLARRPLAGRVGRTMFIAVGVFG 311 GATALLPV+A DIL TG GLGLLRSAPA GALA++ LA + VGR MF++VG+FG Sbjct: 235 GATALLPVFAKDILLTGPWGLGLLRSAPAVGALAMSFWLAHFSIERNVGRIMFLSVGIFG 294 Query: 312 LATIVFGLSRSFPLSLAALAVLGAADMISVVVRSSFVQLETPDAMRGRVSAVNSVFIGTS 371 LATI FGLS+SF LSL L VLGAADM+S+V+R +FVQLETPD MRGRVSAVN +FIG S Sbjct: 295 LATIAFGLSKSFWLSLGVLVVLGAADMVSMVIRGAFVQLETPDEMRGRVSAVNGLFIGAS 354 Query: 372 NQLGEFESGLTAAWFGAVPAVLIGGIGTLLIVLLWIRLFPALYQVDRL 419 NQLGEFESGLTA WFG VPAV++GGIGTL++ W++LFP+L Q DRL Sbjct: 355 NQLGEFESGLTAHWFGTVPAVVLGGIGTLVVTGAWMKLFPSLAQRDRL 402 >SMc03237 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 415 Score = 333 bits (853), Expect = 6e-91, Method: Compositional matrix adjust. Identities = 183/398 (45%), Positives = 262/398 (65%), Gaps = 5/398 (1%) Query: 22 HHTPFKLFWCASVASTIALQMQIVAVGWQVYQLTHSAFDLGIVGLVQFIPSLILVFVVGH 81 H ++ ++ + + + A+Q+ VAVGWQ+Y LT F LG++GL QF+PSL+L+ V G Sbjct: 14 RHVGYRRYFFSRLLAYFAVQIMSVAVGWQIYDLTRDPFSLGLIGLFQFLPSLVLILVTGS 73 Query: 82 VADRFDRRNVARISALVEASAAATLALGSLGGWLNREMIFVIVAVIGAGRAFSKPTMSAL 141 VADR++RR + I LV A L L ++ G + ++ I+ V G RAF P +L Sbjct: 74 VADRYNRRAIMGICMLVSTLCGAALLLLTVTGLFSPWPVYAILVVFGIERAFLGPASQSL 133 Query: 142 LPSLMSPRALPGAVAGSASATQFAIIIGPALGGFLYVAGPAVVYASSCALFALCSLLLWL 201 P+L+ LP A+A ++++ Q A+I+GP GG LY GP V YA S FA +L+++ Sbjct: 134 APNLVPAEDLPNAIAWNSTSWQTAMIVGPVAGGLLYGFGPTVPYAVSLGFFAAGALMVFA 193 Query: 202 IRRPPQADLAGATKPTGASLSSVFAGLAFIRSKPAIFGAISLDMFAVLLGGATALLPVYA 261 + +P A + P+ A+ ++ AG +I+++ + GAISLD+FAVLLGGA AL+PV+A Sbjct: 194 VPKP-----ARRSPPSAANWQTITAGFRYIKAEKIVLGAISLDLFAVLLGGAVALMPVFA 248 Query: 262 NDILHTGAVGLGLLRSAPAAGALAVALLLARRPLAGRVGRTMFIAVGVFGLATIVFGLSR 321 D+L G GLGLLR+AP GA+ +A+ LA P+ R G MF+ V +FGLAT+VFGLS Sbjct: 249 RDVLTLGPWGLGLLRAAPGVGAVGMAVWLAAHPIRNRAGLYMFVGVALFGLATVVFGLSA 308 Query: 322 SFPLSLAALAVLGAADMISVVVRSSFVQLETPDAMRGRVSAVNSVFIGTSNQLGEFESGL 381 + +S+AAL V+GA+DMISV VR + L TPD +RGRV+AVN VF+G SN+LGEF +G+ Sbjct: 309 TPWISIAALVVMGASDMISVYVREILITLWTPDELRGRVNAVNMVFVGASNELGEFRAGM 368 Query: 382 TAAWFGAVPAVLIGGIGTLLIVLLWIRLFPALYQVDRL 419 A+ FG V AV+ GG GTLL+ LLW FP L ++D L Sbjct: 369 MASGFGTVFAVVFGGAGTLLVSLLWALGFPQLRRIDTL 406 >mlr4214 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 412 Score = 328 bits (842), Expect = 1e-89, Method: Compositional matrix adjust. Identities = 193/416 (46%), Positives = 254/416 (61%), Gaps = 5/416 (1%) Query: 8 TAPDEASEQQLPLRHHTPFKLFWCASVASTIALQMQIVAVGWQVYQLTHSAFDLGIVGLV 67 T+ + EQ+ H F +W A +T A + VAVGWQ+Y LT FDLGIVG+V Sbjct: 2 TSLQTSPEQRYAAFRHKAFLSYWTARFLTTFATMVVSVAVGWQMYDLTRDPFDLGIVGIV 61 Query: 68 QFIPSLILVFVVGHVADRFDRRNVARISALVEASAAATLALGSLGGWLNREMIFVIVAVI 127 QF+PSL+LV V G VADRF RR + ++ +VEA A L +L IF ++A+ Sbjct: 62 QFLPSLLLVLVTGAVADRFGRRLIMALAVVVEAICALALLALTLRSISGPLPIFCVLAMF 121 Query: 128 GAGRAFSKPTMSALLPSLMSPRALPGAVAGSASATQFAIIIGPALGGFLYVAGPAVVYAS 187 G RAF P ++L +L+ P A+A ++SA Q A I+GP GG LY P V Y + Sbjct: 122 GVARAFFGPASASLFANLVPPEDFANAIAWNSSAWQTATIVGPVAGGLLYGVSPEVAYGT 181 Query: 188 SCALFALCSLLLWLIRRPPQADLAGATKPTGASLSSVFAGLAFIRSKPAIFGAISLDMFA 247 + L LL++ I +P Q KPT L ++F G ++I S+ + GAISLD+FA Sbjct: 182 AAVLMLASGLLIFTIPKPAQRT--ETEKPT---LQNLFGGFSYIWSEKIVLGAISLDLFA 236 Query: 248 VLLGGATALLPVYANDILHTGAVGLGLLRSAPAAGALAVALLLARRPLAGRVGRTMFIAV 307 VLL GA+ALLPVYA DIL G GLGLLRSAP+ GA+ VA+ LA P+ G M A Sbjct: 237 VLLSGASALLPVYARDILQLGPWGLGLLRSAPSIGAICVAVWLAGHPMRNHAGMIMLAAA 296 Query: 308 GVFGLATIVFGLSRSFPLSLAALAVLGAADMISVVVRSSFVQLETPDAMRGRVSAVNSVF 367 FG T++FGLS LS+AAL LGA DM SV +R + +QL TPD +RGRV+AVN VF Sbjct: 297 ASFGAFTVLFGLSTITWLSIAALVFLGATDMFSVYIRETLIQLWTPDEVRGRVNAVNQVF 356 Query: 368 IGTSNQLGEFESGLTAAWFGAVPAVLIGGIGTLLIVLLWIRLFPALYQVDRLAARR 423 +G SN++GEF +G AA G VPAV+IGG+G + + LW+ LFP L +V L R Sbjct: 357 VGASNEVGEFRAGTMAALIGTVPAVVIGGVGAIAVAGLWMVLFPQLRKVRHLNGRN 412