BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.2683.p (1077 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp1198 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia s... 1228 0.0 PA2527 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas ... 1217 0.0 YPO2848 [V] COG0841 Cation/multidrug efflux pump Ype Yersinia pe... 1204 0.0 ZyegN [V] COG0841 Cation/multidrug efflux pump EcZ Escherichia c... 1164 0.0 ECs2883 [V] COG0841 Cation/multidrug efflux pump Ecs Escherichia... 1164 0.0 >RSp1198 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia solanacearum Length = 1041 Score = 1228 bits (3176), Expect = 0.0, Method: Compositional matrix adjust. Identities = 639/1070 (59%), Positives = 804/1070 (75%), Gaps = 45/1070 (4%) Query: 1 MNPSSLFIRRPVATLLLMIAVVLSGMFAYRTLSISALPQVDYPTIQVTTLYPGAGPEVMT 60 MNPS +FI RPVAT LLM+A++LSG+ AYR L +SALP+VDYPTIQVTTLYPGA P+VMT Sbjct: 1 MNPSRIFILRPVATTLLMVAILLSGLVAYRMLPLSALPEVDYPTIQVTTLYPGASPDVMT 60 Query: 61 TAVTAPLERQLGQMAGLAQMYSTSAGGASVITLKFNLALSLDVAEQEVQAAINAANALLP 120 +++TAPLERQ GQM GL QM S S+GGASVITL+F+L+LSLD+AEQEVQAAINAA LLP Sbjct: 61 SSITAPLERQFGQMPGLKQMTSASSGGASVITLQFDLSLSLDIAEQEVQAAINAAGNLLP 120 Query: 121 SGLPNPPTYKKVNPADTAVLTLAATSESLPLTQVQDLVNTRIALKLSQVSGVGLVTLAGG 180 + LP PP Y KVNPAD +LTLA TS +LPL +++D+V+TR+A KLSQ+ G+GLV+++GG Sbjct: 121 TDLPMPPIYSKVNPADAPILTLAITSRTLPLPKLEDIVDTRVAQKLSQLPGIGLVSISGG 180 Query: 181 QQLAIRVRANPTALAAHGLTLENLYNVINNGNVNGSKGGFDGPAHSVTIDANDQLRSAEE 240 Q+ A+R++AN ALAA GL+++++ I N NVNG+KG FDGP + TIDANDQLRSA E Sbjct: 181 QRPAVRIQANTQALAALGLSIDDIRTAIGNANVNGAKGSFDGPMRASTIDANDQLRSAAE 240 Query: 241 YGNLVVAYQNGQALFLRDVASIDQAPENIYQAAWAGNKPAIVINIQRQPGANVVQVVDSI 300 YG ++VAY+NG + L DVA I EN AAWA PAI++N+QRQPGANV+ VV+ Sbjct: 241 YGTMIVAYKNGAPIRLTDVAQIIDGAENSKLAAWANTTPAIILNVQRQPGANVIDVVNRA 300 Query: 301 KALLPSLQQSLPGAVKLEILSDRTQTIRASISDVQFELMLSIALVVMVSFLFLRTVSATL 360 KALLP L+ +LP + + +L+DRT TIRAS++DVQFEL+L++ALVVMV FLFLR + AT+ Sbjct: 301 KALLPQLKDTLPANIDVAVLTDRTTTIRASVADVQFELLLAVALVVMVIFLFLRNIPATI 360 Query: 361 IPSVAVPLSLVGTFGVMYLAGFSLNNLTLMALTIATGFVIDDAIVVVENIQRHLENGDSP 420 IP+VAVPLSLVGTFGVMYLAGFS+NNLTLMALTIATGFV+DDAIV++ENI R++E+GD P Sbjct: 361 IPAVAVPLSLVGTFGVMYLAGFSVNNLTLMALTIATGFVVDDAIVMIENIARYIEDGDPP 420 Query: 421 MEAAFKGSREIGFTIISLTFSLIAVLIPLLFMGDVVGRLFREFSITLAVSILVSMLVSLT 480 MEAA KG+R+IGFTIISLTFSLIAVLIPLLFM DVVGRLFREF+ITLAVSIL+S +VSLT Sbjct: 421 MEAALKGARQIGFTIISLTFSLIAVLIPLLFMSDVVGRLFREFAITLAVSILISAVVSLT 480 Query: 481 LTPMLCAYLLRHIPPEQEGRFARWSAGRFDRLLQAYERSLGWVLGHQRLTLLVAAASLVL 540 LTPM+CA LLRHIP ++ RF + FD ++ Y R L WVL QR TLLVA +L L Sbjct: 481 LTPMMCARLLRHIPEPEQTRFYHAAGQFFDNVIAQYGRMLQWVLDRQRTTLLVAIGTLAL 540 Query: 541 TALLYMAVPKGFFPTQDTGQLLGVTTAPQNVSFAEMSRRQQALAAVIQQDPAVKSISSVV 600 T LLY+ VPKGFFP QDTG + G++ A Q++SF M+ RQQ LA VI +DPAV+S+SS + Sbjct: 541 TGLLYVYVPKGFFPVQDTGVIQGISDATQSISFPAMAERQQKLAEVILKDPAVESLSSFI 600 Query: 601 GVDGANNTSLSNGRLQIELKSFDERSDRAPVIIERLRAAAAQVPGIQLYLTASQDLSVDD 660 GVDG NT+L++GR+ I LK D R A II+RL+ A+V GI L++ QDL+++D Sbjct: 601 GVDG-TNTTLNSGRMLINLKPKDARDADATEIIQRLQPELAKVGGISLFMQPVQDLTIED 659 Query: 661 QVTPSQYQLTLSTPTQSDLEAWAPRLVAALAKHPELRDITSNLQNSSPVAYVDMNRMALA 720 +V+ +QYQ T+ P ++L W PRLV L + ELRD+ S+LQ++ AYV ++R A Sbjct: 660 RVSRTQYQFTVEDPDPNNLSKWVPRLVERLQQTGELRDVASDLQDNGLRAYVQIDRDKAA 719 Query: 721 RYGLTATDVDTALYNAYGQRLVSTIFTQANQYRVVLEVAPQFRQDVSAFDQLYLANANST 780 YG+T VD+ALY+AYGQRL+STIFTQ+NQYRVVLE APQ ++ + L +A+ Sbjct: 720 VYGVTTAAVDSALYSAYGQRLISTIFTQSNQYRVVLEAAPQLQKGPQSLYDLRVASTGGQ 779 Query: 781 SSSSSSTSSSSSSSSSSSSSSSSSASSTSSSTSTSSSTTLTPMVPLRNVARIQERVGYQS 840 VPL A + E+ G Sbjct: 780 Q------------------------------------------VPLGAFATVVEQPGSLV 797 Query: 841 RSRLNQTPAVTLSFNLGKGYSLEQARAAVSEAVQEIGLPDTISLRYQGAAQAFASATSNT 900 + Q P+ T+SFNL +G SL A A++ A Q IGLP ++ +QGAA AF S+ SN Sbjct: 798 VNHQGQFPSATISFNLARGASLGAAVDAINAAEQAIGLPASMQTSFQGAALAFQSSLSNE 857 Query: 901 LWLILAAVITMYIVLGVLYESFIHPVTVLSTLPSAAIGALLALLLTGSDFSLIALIGVIL 960 LWLILAA+ITMYIVLGVLYES IHPVT+LSTLPSA +GALL+LL++G D +IA+IG+IL Sbjct: 858 LWLILAAIITMYIVLGVLYESTIHPVTILSTLPSAGVGALLSLLVSGKDMGIIAIIGIIL 917 Query: 961 LIGIVKKNAIMMIDFALQAQKE-GKSAFDAIQQACVMRFRPIMMTTMAALLGAVPLMLAT 1019 LIGIVKKNAIMMIDFAL+A++E G + DAI QAC++RFRPI+MTTMAALLGA+PLML T Sbjct: 918 LIGIVKKNAIMMIDFALEAEREQGMAPRDAIYQACLLRFRPILMTTMAALLGALPLMLGT 977 Query: 1020 GSGAELRRPLGLVIVGGLLLSQLLTLFTTPVIYLFFDRASVAVKRRWAAR 1069 G G+ELR+PLG+ +VGGLL+SQ+LTLFTTPVIYL FD + R W R Sbjct: 978 GVGSELRQPLGITMVGGLLVSQVLTLFTTPVIYLAFDSLGHRL-RDWRER 1026 >PA2527 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas aeruginosa Length = 1043 Score = 1217 bits (3148), Expect = 0.0, Method: Compositional matrix adjust. Identities = 650/1069 (60%), Positives = 821/1069 (76%), Gaps = 48/1069 (4%) Query: 1 MNPSSLFIRRPVATLLLMIAVVLSGMFAYRTLSISALPQVDYPTIQVTTLYPGAGPEVMT 60 MNPS FI RPVAT LLM+A++LSG+ AYR L ISALP+VDYPTIQV TLYPGA PE+MT Sbjct: 1 MNPSRPFILRPVATTLLMVAILLSGLIAYRFLPISALPEVDYPTIQVVTLYPGASPEIMT 60 Query: 61 TAVTAPLERQLGQMAGLAQMYSTSAGGASVITLKFNLALSLDVAEQEVQAAINAANALLP 120 +++TAPLE QLGQ+ GL +M S+S+GGASVITL+F+L +LDVAEQEVQAAINAA +LLP Sbjct: 61 SSITAPLENQLGQIPGLNEMSSSSSGGASVITLQFSLQSNLDVAEQEVQAAINAAQSLLP 120 Query: 121 SGLPNPPTYKKVNPADTAVLTLAATSESLPLTQVQDLVNTRIALKLSQVSGVGLVTLAGG 180 + LPN P + KVNPAD +LTLA S+ +PL Q+QDLV+TR+A K+SQ+SGVGLV+++GG Sbjct: 121 NDLPNQPVFSKVNPADAPILTLAVMSDGMPLPQIQDLVDTRLAQKISQISGVGLVSISGG 180 Query: 181 QQLAIRVRANPTALAAHGLTLENLYNVINNGNVNGSKGGFDGPAHSVTIDANDQLRSAEE 240 Q+ A+RVRANPTALAA GL+LE+L + + + N+NG KG FDGP + T+DANDQLRSA+ Sbjct: 181 QRPAVRVRANPTALAAAGLSLEDLRSTVTSNNLNGPKGSFDGPTRASTLDANDQLRSADA 240 Query: 241 YGNLVVAYQNGQALFLRDVASIDQAPENIYQAAWAGNKPAIVINIQRQPGANVVQVVDSI 300 Y +L++AY+NG L +RDVAS++ EN+ AAWA N PA+V+NIQRQPGANV++VVD I Sbjct: 241 YRDLIIAYKNGSPLRIRDVASVEDDAENVRLAAWANNLPAVVLNIQRQPGANVIEVVDRI 300 Query: 301 KALLPSLQQSLPGAVKLEILSDRTQTIRASISDVQFELMLSIALVVMVSFLFLRTVSATL 360 KALLP LQ +LPG + +++L+DRT TIRAS+ DVQFEL L++ALVVMV+FLFLR V ATL Sbjct: 301 KALLPQLQSTLPGNLDVQVLTDRTTTIRASVKDVQFELALAVALVVMVTFLFLRNVYATL 360 Query: 361 IPSVAVPLSLVGTFGVMYLAGFSLNNLTLMALTIATGFVIDDAIVVVENIQRHLENGDSP 420 IPS AVPLSL+GTFGVMYL+GFS+NNLTLMALTIATGFV+DDAIV+VENI R+LE GDSP Sbjct: 361 IPSFAVPLSLIGTFGVMYLSGFSINNLTLMALTIATGFVVDDAIVMVENIARYLEQGDSP 420 Query: 421 MEAAFKGSREIGFTIISLTFSLIAVLIPLLFMGDVVGRLFREFSITLAVSILVSMLVSLT 480 +EAA KGS++IGFTIISLTFSLIAVLIPLLFMGDV GRLFREF+ITLAV+IL+S VSLT Sbjct: 421 LEAALKGSKQIGFTIISLTFSLIAVLIPLLFMGDVAGRLFREFAITLAVAILISGFVSLT 480 Query: 481 LTPMLCAYLLRHIPPEQEGRFARWSAGRFDRLLQAYERSLGWVLGHQRLTLLVAAASLVL 540 LTPML A LLRHI +Q+GRFAR + D L+ Y ++L VL HQ LTLLVA A+L L Sbjct: 481 LTPMLSAKLLRHIDEDQQGRFARAAGRVIDGLIAQYAKALRVVLRHQPLTLLVAIATLAL 540 Query: 541 TALLYMAVPKGFFPTQDTGQLLGVTTAPQNVSFAEMSRRQQALAAVIQQDPAVKSISSVV 600 TALLY+A+PKGFFP QDTG + GV APQ++SF MS RQ+ALA V+ +DPAV S+SS + Sbjct: 541 TALLYLAMPKGFFPVQDTGVIQGVAEAPQSISFQAMSERQRALAEVVLKDPAVASLSSYI 600 Query: 601 GVDGANNTSLSNGRLQIELKSFDERSDRAPVIIERLRAAAAQVPGIQLYLTASQDLSVDD 660 GVDG+N T L+ GRL I LK ER A +I+RL+ +PGI+LY+ QDL+++D Sbjct: 601 GVDGSNPT-LNTGRLLINLKPHSERDVTASEVIQRLQPELDHLPGIKLYMQPVQDLTIED 659 Query: 661 QVTPSQYQLTLSTPTQSDLEAWAPRLVAALAKHPELRDITSNLQNSSPVAYVDMNRMALA 720 +V +QYQ TL L W P+LVA L + P+L D+ S+ Q+ AY++++R + Sbjct: 660 RVARTQYQFTLQDADPDVLAEWVPKLVARLQELPQLADVASDWQDKGLQAYLNIDRDTAS 719 Query: 721 RYGLTATDVDTALYNAYGQRLVSTIFTQANQYRVVLEVAPQFRQDVSAFDQLYLANANST 780 R G+ +D+D+ LYNA+GQRL+STIFTQA QYRVVLEVAPQF+ A +QLY+ +++ T Sbjct: 720 RLGVKLSDIDSVLYNAFGQRLISTIFTQATQYRVVLEVAPQFQLGPQALEQLYVPSSDGT 779 Query: 781 SSSSSSTSSSSSSSSSSSSSSSSSASSTSSSTSTSSSTTLTPMVPLRNVARIQERVGYQS 840 V L ++A+++ER + Sbjct: 780 Q------------------------------------------VRLSSLAKVEERHTLLA 797 Query: 841 RSRLNQTPAVTLSFNLGKGYSLEQARAAVSEAVQEIGLPDTISLRYQGAAQAFASATSNT 900 + + Q P+ TLSFNL KGYSL +A A+ + LP ++ ++GAA AF ++ SNT Sbjct: 798 INHIAQFPSATLSFNLAKGYSLGEAVEAIRGVEASLELPLSMQGSFRGAALAFEASLSNT 857 Query: 901 LWLILAAVITMYIVLGVLYESFIHPVTVLSTLPSAAIGALLALLLTGSDFSLIALIGVIL 960 L LILA+V+TMYIVLG+LYESFIHPVT+LSTLPSA +GALLAL+L G + ++A+IG+IL Sbjct: 858 LLLILASVVTMYIVLGILYESFIHPVTILSTLPSAGVGALLALMLAGQEIGIVAIIGIIL 917 Query: 961 LIGIVKKNAIMMIDFALQAQK-EGKSAFDAIQQACVMRFRPIMMTTMAALLGAVPLMLAT 1019 LIGIVKKNAIMMIDFAL A++ EGK +AI QAC++RFRPI+MTTMAALLGA+PLMLA Sbjct: 918 LIGIVKKNAIMMIDFALDAERNEGKPPHEAIYQACLLRFRPILMTTMAALLGALPLMLAG 977 Query: 1020 GSGAELRRPLGLVIVGGLLLSQLLTLFTTPVIYLFFDRASVAVKRRWAA 1068 G+GAELR+PLG+ +VGGLLLSQ+LTLFTTPVIYL+FDR + RRWAA Sbjct: 978 GAGAELRQPLGITMVGGLLLSQVLTLFTTPVIYLYFDR----LARRWAA 1022 >YPO2848 [V] COG0841 Cation/multidrug efflux pump Ype Yersinia pestis Length = 1052 Score = 1204 bits (3115), Expect = 0.0, Method: Compositional matrix adjust. Identities = 616/1056 (58%), Positives = 796/1056 (75%), Gaps = 44/1056 (4%) Query: 3 PSSLFIRRPVATLLLMIAVVLSGMFAYRTLSISALPQVDYPTIQVTTLYPGAGPEVMTTA 62 PS LFI RPVAT L MIA++L+G+ YR L +SALP+VDYPTIQV TLYPGA P+V+T++ Sbjct: 12 PSRLFILRPVATTLFMIAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVVTSS 71 Query: 63 VTAPLERQLGQMAGLAQMYSTSAGGASVITLKFNLALSLDVAEQEVQAAINAANALLPSG 122 +TAPLERQ GQM+GL QM S S+GGASVITL+F L L LDVAEQEVQAAINAA LLPS Sbjct: 72 ITAPLERQFGQMSGLKQMASQSSGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSD 131 Query: 123 LPNPPTYKKVNPADTAVLTLAATSESLPLTQVQDLVNTRIALKLSQVSGVGLVTLAGGQQ 182 LP PP Y KVNPAD +LTLA T+ ++P+TQV+D+V TRIA K+SQV+GVGLVTL+GGQ+ Sbjct: 132 LPYPPIYNKVNPADPPILTLAVTATAIPMTQVEDMVETRIAQKISQVTGVGLVTLSGGQR 191 Query: 183 LAIRVRANPTALAAHGLTLENLYNVINNGNVNGSKGGFDGPAHSVTIDANDQLRSAEEYG 242 A+RV+ N A+AA GL E + I+N NVN +KG DGP SVT+ ANDQ++SAEEY Sbjct: 192 PAVRVKLNAPAVAALGLDSETIRTAISNANVNSAKGSLDGPTRSVTLSANDQMKSAEEYR 251 Query: 243 NLVVAYQNGQALFLRDVASIDQAPENIYQAAWAGNKPAIVINIQRQPGANVVQVVDSIKA 302 +L++AYQNG + L+DVA+I+Q EN AAWA + AIV+NIQRQPG NV+ DSI+ Sbjct: 252 DLIIAYQNGAPIRLQDVATIEQGAENNKLAAWANTQSAIVLNIQRQPGVNVIATADSIRE 311 Query: 303 LLPSLQQSLPGAVKLEILSDRTQTIRASISDVQFELMLSIALVVMVSFLFLRTVSATLIP 362 +LP L +SLP +V +++L+DRT TIRAS++DVQFEL+L+IALVVMV +LFLR +AT+IP Sbjct: 312 MLPELIKSLPKSVDVKVLTDRTSTIRASVNDVQFELLLAIALVVMVIYLFLRNAAATIIP 371 Query: 363 SVAVPLSLVGTFGVMYLAGFSLNNLTLMALTIATGFVIDDAIVVVENIQRHLENGDSPME 422 S+AVPLSLVGTF MY GFS+NNLTLMALTIATGFV+DDAIVV+ENI R++E G+ P++ Sbjct: 372 SIAVPLSLVGTFAAMYFLGFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLD 431 Query: 423 AAFKGSREIGFTIISLTFSLIAVLIPLLFMGDVVGRLFREFSITLAVSILVSMLVSLTLT 482 AA KG+ EIGFTIISLTFSLIAVLIPLLFM D+VGRLFREF++TLAV+IL+S +VSLTLT Sbjct: 432 AALKGAGEIGFTIISLTFSLIAVLIPLLFMEDIVGRLFREFAVTLAVAILISAVVSLTLT 491 Query: 483 PMLCAYLLRHIPPEQEGRFARWSAGRFDRLLQAYERSLGWVLGHQRLTLLVAAASLVLTA 542 PM+CA +L + ++ R +R S FD ++ Y +L VL H LTL VA ++LVLT Sbjct: 492 PMMCARMLSYESLRKQNRLSRASEKFFDWVIAHYAVALKKVLNHPWLTLSVAFSTLVLTV 551 Query: 543 LLYMAVPKGFFPTQDTGQLLGVTTAPQNVSFAEMSRRQQALAAVIQQDPAVKSISSVVGV 602 +LY+ +PKGFFP QD G + G APQ+VSF+ M+ RQQ +AA+I +DPAV+S++S VGV Sbjct: 552 ILYLLIPKGFFPLQDNGLIQGTLEAPQSVSFSNMAERQQQVAAIILKDPAVESLTSFVGV 611 Query: 603 DGANNTSLSNGRLQIELKSFDERSDRAPVIIERLRAAAAQVPGIQLYLTASQDLSVDDQV 662 DG N T L+NGRLQI LK ER DR P II RL+ + + VPGI+LYL QDL++D Q+ Sbjct: 612 DGTNAT-LNNGRLQINLKPLSERDDRIPQIITRLQESVSGVPGIKLYLQPVQDLTIDTQL 670 Query: 663 TPSQYQLTLSTPTQSDLEAWAPRLVAALAKHPELRDITSNLQNSSPVAYVDMNRMALARY 722 + +QYQ TL + +L W P+LV L + +D+TS+ Q+ VA+V+++R + +R Sbjct: 671 SRTQYQFTLQATSLEELSTWVPKLVNELQQKAPFQDVTSDWQDQGLVAFVNVDRDSASRL 730 Query: 723 GLTATDVDTALYNAYGQRLVSTIFTQANQYRVVLEVAPQFRQDVSAFDQLYLANANSTSS 782 G+T +D ALYNA+GQRL+STI+TQ+NQYRVVLE Q ++AF+ + L + Sbjct: 731 GITMAAIDNALYNAFGQRLISTIYTQSNQYRVVLEHDVQATPGLAAFNDIRLTGIDGKG- 789 Query: 783 SSSSTSSSSSSSSSSSSSSSSSASSTSSSTSTSSSTTLTPMVPLRNVARIQERVGYQSRS 842 VPL ++A I+ER G S + Sbjct: 790 -----------------------------------------VPLSSIATIEERFGPLSIN 808 Query: 843 RLNQTPAVTLSFNLGKGYSLEQARAAVSEAVQEIGLPDTISLRYQGAAQAFASATSNTLW 902 LNQ P+ T+SFNL +GYSL +A AAV+ A +EI LP I+ R+QG+ AF +A +TLW Sbjct: 809 HLNQFPSATVSFNLAQGYSLGEAVAAVTLAEKEIQLPADITTRFQGSTLAFQAALGSTLW 868 Query: 903 LILAAVITMYIVLGVLYESFIHPVTVLSTLPSAAIGALLALLLTGSDFSLIALIGVILLI 962 LI+AA++ MYIVLGVLYESFIHP+T+LSTLP+A +GALLAL+LTG++ +IA+IG+ILLI Sbjct: 869 LIIAAIVAMYIVLGVLYESFIHPITILSTLPTAGVGALLALMLTGNELDVIAIIGIILLI 928 Query: 963 GIVKKNAIMMIDFALQAQKE-GKSAFDAIQQACVMRFRPIMMTTMAALLGAVPLMLATGS 1021 GIVKKNAIMMIDFAL A+++ G + +DAI QAC++RFRPI+MTT+AAL GA+PLML+TG Sbjct: 929 GIVKKNAIMMIDFALAAERDQGMTPYDAIYQACLLRFRPILMTTLAALFGALPLMLSTGV 988 Query: 1022 GAELRRPLGLVIVGGLLLSQLLTLFTTPVIYLFFDR 1057 GAELR+PLG+ +VGGL++SQ+LTLFTTPVIYL FD+ Sbjct: 989 GAELRQPLGVCMVGGLIVSQVLTLFTTPVIYLLFDK 1024 >ZyegN [V] COG0841 Cation/multidrug efflux pump EcZ Escherichia coli O157:H7 EDL933 Length = 1040 Score = 1164 bits (3011), Expect = 0.0, Method: Compositional matrix adjust. Identities = 613/1066 (57%), Positives = 794/1066 (74%), Gaps = 44/1066 (4%) Query: 3 PSSLFIRRPVATLLLMIAVVLSGMFAYRTLSISALPQVDYPTIQVTTLYPGAGPEVMTTA 62 PS LFI RPVAT LLM+A++L+G+ YR L +SALP+VDYPTIQV TLYPGA P+VMT+A Sbjct: 12 PSRLFIMRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSA 71 Query: 63 VTAPLERQLGQMAGLAQMYSTSAGGASVITLKFNLALSLDVAEQEVQAAINAANALLPSG 122 VTAPLERQ GQM+GL QM S S+GGASVITL+F L L LDVAEQEVQAAINAA LLPS Sbjct: 72 VTAPLERQFGQMSGLKQMSSQSSGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSD 131 Query: 123 LPNPPTYKKVNPADTAVLTLAATSESLPLTQVQDLVNTRIALKLSQVSGVGLVTLAGGQQ 182 LPNPP Y KVNPAD ++TLA TS ++P+TQV+D+V TR+A K+SQ+SGVGLVTL+GGQ+ Sbjct: 132 LPNPPVYSKVNPADPPIMTLAVTSTAMPMTQVEDMVETRVAQKISQISGVGLVTLSGGQR 191 Query: 183 LAIRVRANPTALAAHGLTLENLYNVINNGNVNGSKGGFDGPAHSVTIDANDQLRSAEEYG 242 A+RV+ N A+AA GLT E + I NVN +KG DGP+ +VT+ ANDQ++SAEEY Sbjct: 192 PAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPSRAVTLSANDQMQSAEEYR 251 Query: 243 NLVVAYQNGQALFLRDVASIDQAPENIYQAAWAGNKPAIVINIQRQPGANVVQVVDSIKA 302 L++AYQNG + L DVA+++Q EN + AWA + AIV+N+QRQPGAN++ DSI+ Sbjct: 252 QLIIAYQNGAPIRLGDVATVEQGAENSWLGAWANKEQAIVMNVQRQPGANIISTADSIRQ 311 Query: 303 LLPSLQQSLPGAVKLEILSDRTQTIRASISDVQFELMLSIALVVMVSFLFLRTVSATLIP 362 +LP L +SLP +VK+ +LSDRT IRAS+ D QFELM++IALVVM+ +LFLR + AT+IP Sbjct: 312 MLPQLTESLPKSVKVTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIP 371 Query: 363 SVAVPLSLVGTFGVMYLAGFSLNNLTLMALTIATGFVIDDAIVVVENIQRHLENGDSPME 422 VAVPLSL+GTF VM FS+NNLTLMALTIATGFV+DDAIVV+ENI R++E G+ P+ Sbjct: 372 GVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLA 431 Query: 423 AAFKGSREIGFTIISLTFSLIAVLIPLLFMGDVVGRLFREFSITLAVSILVSMLVSLTLT 482 AA KG+ EIGFTIISLTFSLIAVLIPLLFMGD+VGRLFREF+ITLAV+IL+S +VSLTLT Sbjct: 432 AALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLT 491 Query: 483 PMLCAYLLRHIPPEQEGRFARWSAGRFDRLLQAYERSLGWVLGHQRLTLLVAAASLVLTA 542 PM+CA +L ++ RF+R S FDR++ AY R L VL H LTL VA ++L+L+ Sbjct: 492 PMMCARMLSQESLRKQNRFSRASEKMFDRIIAAYGRGLAKVLNHPWLTLSVALSTLLLSV 551 Query: 543 LLYMAVPKGFFPTQDTGQLLGVTTAPQNVSFAEMSRRQQALAAVIQQDPAVKSISSVVGV 602 LL++ +PKGFFP QD G + G APQ+ SFA M++RQ+ +A VI QDPAV+S++S VGV Sbjct: 552 LLWVFIPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGV 611 Query: 603 DGANNTSLSNGRLQIELKSFDERSDRAPVIIERLRAAAAQVPGIQLYLTASQDLSVDDQV 662 DG N SL++ RLQI LK DER DR +I RL+ A +VPG+ L+L +QDL++D QV Sbjct: 612 DG-TNPSLNSARLQINLKPLDERDDRVQKVIARLQTAVDKVPGVDLFLQPTQDLTIDTQV 670 Query: 663 TPSQYQLTLSTPTQSDLEAWAPRLVAALAKHPELRDITSNLQNSSPVAYVDMNRMALARY 722 + +QYQ TL + L W P+L+ L + P++ D++S+ Q+ VAYV+++R + +R Sbjct: 671 SRTQYQFTLQATSLDALSTWVPQLMEKLQQLPQISDVSSDWQDKGLVAYVNVDRDSASRL 730 Query: 723 GLTATDVDTALYNAYGQRLVSTIFTQANQYRVVLEVAPQFRQDVSAFDQLYLANANSTSS 782 G++ DVD ALYNA+GQRL+STI+TQANQYRVVLE + ++A D + L TSS Sbjct: 731 GISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRL-----TSS 785 Query: 783 SSSSTSSSSSSSSSSSSSSSSSASSTSSSTSTSSSTTLTPMVPLRNVARIQERVGYQSRS 842 +VPL ++A+I++R S + Sbjct: 786 DGG-------------------------------------VVPLSSIAKIEQRFAPLSIN 808 Query: 843 RLNQTPAVTLSFNLGKGYSLEQARAAVSEAVQEIGLPDTISLRYQGAAQAFASATSNTLW 902 L+Q P T+SFN+ YSL A A+ + + + LP I+ ++QG+ AF SA +T+W Sbjct: 809 HLDQFPVTTISFNVPDNYSLGDAVQAIMDTEKTLNLPVDITTQFQGSTLAFQSALGSTVW 868 Query: 903 LILAAVITMYIVLGVLYESFIHPVTVLSTLPSAAIGALLALLLTGSDFSLIALIGVILLI 962 LI+AAV+ MYIVLG+LYESFIHP+T+LSTLP+A +GALLAL++ GS+ +IA+IG+ILLI Sbjct: 869 LIVAAVVAMYIVLGILYESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLI 928 Query: 963 GIVKKNAIMMIDFALQAQKE-GKSAFDAIQQACVMRFRPIMMTTMAALLGAVPLMLATGS 1021 GIVKKNAIMMIDFAL A++E G S DAI QAC++RFRPI+MTT+AALLGA+PLML+TG Sbjct: 929 GIVKKNAIMMIDFALAAEREQGMSPRDAIYQACLLRFRPILMTTLAALLGALPLMLSTGV 988 Query: 1022 GAELRRPLGLVIVGGLLLSQLLTLFTTPVIYLFFDRASVAVKRRWA 1067 GAELRRPLG+ +VGGL++SQ+LTLFTTPVIYL FDR ++ K R+A Sbjct: 989 GAELRRPLGIGMVGGLIVSQVLTLFTTPVIYLLFDRLALWTKSRFA 1034 >ECs2883 [V] COG0841 Cation/multidrug efflux pump Ecs Escherichia coli O157:H7 Length = 1040 Score = 1164 bits (3011), Expect = 0.0, Method: Compositional matrix adjust. Identities = 613/1066 (57%), Positives = 794/1066 (74%), Gaps = 44/1066 (4%) Query: 3 PSSLFIRRPVATLLLMIAVVLSGMFAYRTLSISALPQVDYPTIQVTTLYPGAGPEVMTTA 62 PS LFI RPVAT LLM+A++L+G+ YR L +SALP+VDYPTIQV TLYPGA P+VMT+A Sbjct: 12 PSRLFIMRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSA 71 Query: 63 VTAPLERQLGQMAGLAQMYSTSAGGASVITLKFNLALSLDVAEQEVQAAINAANALLPSG 122 VTAPLERQ GQM+GL QM S S+GGASVITL+F L L LDVAEQEVQAAINAA LLPS Sbjct: 72 VTAPLERQFGQMSGLKQMSSQSSGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSD 131 Query: 123 LPNPPTYKKVNPADTAVLTLAATSESLPLTQVQDLVNTRIALKLSQVSGVGLVTLAGGQQ 182 LPNPP Y KVNPAD ++TLA TS ++P+TQV+D+V TR+A K+SQ+SGVGLVTL+GGQ+ Sbjct: 132 LPNPPVYSKVNPADPPIMTLAVTSTAMPMTQVEDMVETRVAQKISQISGVGLVTLSGGQR 191 Query: 183 LAIRVRANPTALAAHGLTLENLYNVINNGNVNGSKGGFDGPAHSVTIDANDQLRSAEEYG 242 A+RV+ N A+AA GLT E + I NVN +KG DGP+ +VT+ ANDQ++SAEEY Sbjct: 192 PAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPSRAVTLSANDQMQSAEEYR 251 Query: 243 NLVVAYQNGQALFLRDVASIDQAPENIYQAAWAGNKPAIVINIQRQPGANVVQVVDSIKA 302 L++AYQNG + L DVA+++Q EN + AWA + AIV+N+QRQPGAN++ DSI+ Sbjct: 252 QLIIAYQNGAPIRLGDVATVEQGAENSWLGAWANKEQAIVMNVQRQPGANIISTADSIRQ 311 Query: 303 LLPSLQQSLPGAVKLEILSDRTQTIRASISDVQFELMLSIALVVMVSFLFLRTVSATLIP 362 +LP L +SLP +VK+ +LSDRT IRAS+ D QFELM++IALVVM+ +LFLR + AT+IP Sbjct: 312 MLPQLTESLPKSVKVTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIP 371 Query: 363 SVAVPLSLVGTFGVMYLAGFSLNNLTLMALTIATGFVIDDAIVVVENIQRHLENGDSPME 422 VAVPLSL+GTF VM FS+NNLTLMALTIATGFV+DDAIVV+ENI R++E G+ P+ Sbjct: 372 GVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLA 431 Query: 423 AAFKGSREIGFTIISLTFSLIAVLIPLLFMGDVVGRLFREFSITLAVSILVSMLVSLTLT 482 AA KG+ EIGFTIISLTFSLIAVLIPLLFMGD+VGRLFREF+ITLAV+IL+S +VSLTLT Sbjct: 432 AALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLT 491 Query: 483 PMLCAYLLRHIPPEQEGRFARWSAGRFDRLLQAYERSLGWVLGHQRLTLLVAAASLVLTA 542 PM+CA +L ++ RF+R S FDR++ AY R L VL H LTL VA ++L+L+ Sbjct: 492 PMMCARMLSQESLRKQNRFSRASEKMFDRIIAAYGRGLAKVLNHPWLTLSVALSTLLLSV 551 Query: 543 LLYMAVPKGFFPTQDTGQLLGVTTAPQNVSFAEMSRRQQALAAVIQQDPAVKSISSVVGV 602 LL++ +PKGFFP QD G + G APQ+ SFA M++RQ+ +A VI QDPAV+S++S VGV Sbjct: 552 LLWVFIPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGV 611 Query: 603 DGANNTSLSNGRLQIELKSFDERSDRAPVIIERLRAAAAQVPGIQLYLTASQDLSVDDQV 662 DG N SL++ RLQI LK DER DR +I RL+ A +VPG+ L+L +QDL++D QV Sbjct: 612 DG-TNPSLNSARLQINLKPLDERDDRVQKVIARLQTAVDKVPGVDLFLQPTQDLTIDTQV 670 Query: 663 TPSQYQLTLSTPTQSDLEAWAPRLVAALAKHPELRDITSNLQNSSPVAYVDMNRMALARY 722 + +QYQ TL + L W P+L+ L + P++ D++S+ Q+ VAYV+++R + +R Sbjct: 671 SRTQYQFTLQATSLDALSTWVPQLMEKLQQLPQISDVSSDWQDKGLVAYVNVDRDSASRL 730 Query: 723 GLTATDVDTALYNAYGQRLVSTIFTQANQYRVVLEVAPQFRQDVSAFDQLYLANANSTSS 782 G++ DVD ALYNA+GQRL+STI+TQANQYRVVLE + ++A D + L TSS Sbjct: 731 GISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRL-----TSS 785 Query: 783 SSSSTSSSSSSSSSSSSSSSSSASSTSSSTSTSSSTTLTPMVPLRNVARIQERVGYQSRS 842 +VPL ++A+I++R S + Sbjct: 786 DGG-------------------------------------VVPLSSIAKIEQRFAPLSIN 808 Query: 843 RLNQTPAVTLSFNLGKGYSLEQARAAVSEAVQEIGLPDTISLRYQGAAQAFASATSNTLW 902 L+Q P T+SFN+ YSL A A+ + + + LP I+ ++QG+ AF SA +T+W Sbjct: 809 HLDQFPVTTISFNVPDNYSLGDAVQAIMDTEKTLNLPVDITTQFQGSTLAFQSALGSTVW 868 Query: 903 LILAAVITMYIVLGVLYESFIHPVTVLSTLPSAAIGALLALLLTGSDFSLIALIGVILLI 962 LI+AAV+ MYIVLG+LYESFIHP+T+LSTLP+A +GALLAL++ GS+ +IA+IG+ILLI Sbjct: 869 LIVAAVVAMYIVLGILYESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLI 928 Query: 963 GIVKKNAIMMIDFALQAQKE-GKSAFDAIQQACVMRFRPIMMTTMAALLGAVPLMLATGS 1021 GIVKKNAIMMIDFAL A++E G S DAI QAC++RFRPI+MTT+AALLGA+PLML+TG Sbjct: 929 GIVKKNAIMMIDFALAAEREQGMSPRDAIYQACLLRFRPILMTTLAALLGALPLMLSTGV 988 Query: 1022 GAELRRPLGLVIVGGLLLSQLLTLFTTPVIYLFFDRASVAVKRRWA 1067 GAELRRPLG+ +VGGL++SQ+LTLFTTPVIYL FDR ++ K R+A Sbjct: 989 GAELRRPLGIGMVGGLIVSQVLTLFTTPVIYLLFDRLALWTKSRFA 1034