BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.2682.p (1043 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp1199 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia s... 1123 0.0 YPO2849 [V] COG0841 Cation/multidrug efflux pump Ype Yersinia pe... 1112 0.0 yegO [V] COG0841 Cation/multidrug efflux pump Eco Escherichia co... 1104 0.0 ECs2884 [V] COG0841 Cation/multidrug efflux pump Ecs Escherichia... 1103 0.0 ZyegO [V] COG0841 Cation/multidrug efflux pump EcZ Escherichia c... 1097 0.0 >RSp1199 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia solanacearum Length = 1033 Score = 1124 bits (2906), Expect = 0.0, Method: Compositional matrix adjust. Identities = 577/1019 (56%), Positives = 740/1019 (72%), Gaps = 9/1019 (0%) Query: 1 MNLSRPFILRPVATLLLSLALTLLGALAYRMLPVAPLPQVDFPTIMVTASLAGASPETMA 60 MNLS FI RPVAT LL++ + L G A+ +LPV+PLPQVDFPTI V ASL GASPETMA Sbjct: 1 MNLSATFIARPVATALLTIGVALAGIAAFNLLPVSPLPQVDFPTISVNASLPGASPETMA 60 Query: 61 ATIAAPLERAMGQIAGITEMTSSSSQGSTNVIVQFDLERDIDGAARDVQAAINAARSLLP 120 AT+A PLER++G+IAGITEMTS S+ GST V +QFDL RDIDGAARDVQAAINA+RSLLP Sbjct: 61 ATVATPLERSLGRIAGITEMTSQSALGSTRVTLQFDLSRDIDGAARDVQAAINASRSLLP 120 Query: 121 SSLKTLPTYRKANPADAPILLLALTSKTVDKGKLYDLASSKLQQTIAQVQGVGQVSLMGS 180 S L + PTYRK NPADAPI++L LTS T +G+LYD AS+ L Q ++Q+ GVGQV++ G+ Sbjct: 121 SGLPSNPTYRKVNPADAPIMILGLTSDTKSRGELYDAASTILAQKLSQITGVGQVNIGGA 180 Query: 181 ALPAVRIELQPQQLSHYGISLDTVRQVVANATTNLPKGELQGEGLHWWVDANGQLTKASD 240 +LPAVR+EL P L+ YGIS +TVR V+ N PKG L+ W + AN Q A + Sbjct: 181 SLPAVRVELNPTALNKYGISTETVRTVITATNANKPKGMLEAGNRVWTLYANDQARHAEE 240 Query: 241 YTNLVVSYQNGAAVKLSDVARVYDSVQDQYVAGYFNDSPSVMMGITRSSGANMLATIDAI 300 Y L+++Y+NGA V+LSDVA V DSVQD G N PSV++ I R GAN++ T+D I Sbjct: 241 YKPLIIAYRNGAPVRLSDVAEVTDSVQDIRNYGSANGKPSVLLIINRQPGANIIDTVDRI 300 Query: 301 KAQLPIMQKMLPKEVQLSLAMDRSPSIRGSLRETELTLLISTLLVIAVVFLFLRNARAVL 360 A LP ++ +P ++ L + MDR+P+IR SLR+ E TL++S LVI VV+LFLRN RA L Sbjct: 301 NAILPYLRNTIPAQINLDVMMDRTPTIRASLRDVERTLMLSIGLVIMVVYLFLRNLRATL 360 Query: 361 IPAVALPISLIGTCAAMYLLGYSLDTLSLMALIIATGFVVDDAIVVLENISRHLEEGAPP 420 IP+VA+P+SLIGT MYL GYSLD LSLMAL +ATGFVVDDAIVVLEN+SRH+E G P Sbjct: 361 IPSVAVPVSLIGTFGVMYLCGYSLDNLSLMALTVATGFVVDDAIVVLENVSRHIENGMRP 420 Query: 421 LKAALDGSKEVGFTVLSMTASLIAVFLPILLMGSIVGRLFREFAVTLSVSLVLSMIVSLT 480 ++AAL G++EVGFTV+SM+ SLIAVF+P+L+MG IVGRLFREFAVTLSV++++S+ +SLT Sbjct: 421 MQAALKGAREVGFTVVSMSFSLIAVFIPLLMMGGIVGRLFREFAVTLSVAILVSLAISLT 480 Query: 481 LTPMLCSRLLRAHKHDASGAPVQPNVFYRAIERVLNAVSDGYASSLEWVMRHKRLTLLSL 540 TPM+C+RLL+ + +P F+R E N + DGY SL W +RH LTLL L Sbjct: 481 TTPMMCARLLKPASEE------EPGWFHRKTEGFFNLLLDGYRHSLAWALRHSWLTLLIL 534 Query: 541 VLTVALNLFLFTAVQKGFFPDQDTGMLMGQMRADQAASFQSVHPQLLAFSRLIQSDPDVA 600 + TV LN +L+ V KGFFP QD G LMG ++ADQA SFQ++ +L+ F ++Q DP V Sbjct: 535 LATVCLNGYLYVVVPKGFFPQQDVGRLMGFIQADQAISFQAMRTKLVDFIHIVQQDPAVE 594 Query: 601 SVMASTGGGAFGSRNTANFFVSLKDSSQRKSTATEIANRLTRKASGVPGASLFLMAGQDL 660 +V+ TGG N+ F+ LK ++RK +A ++ NRL K + PGA+LFL A QD+ Sbjct: 595 NVVGFTGGSQI---NSGQMFIQLKPLAERKLSADQVINRLRGKLAREPGANLFLQAVQDI 651 Query: 661 RMGGRSANATYQYSLQSDSLDTLREWSPKVYAVLRKLPELTSVDTDAQSGGQAVKLVIDR 720 R+GGR +NA YQY+LQ+D+L+ LR W PK+ L ++ L V+TDAQ GQ LV DR Sbjct: 652 RIGGRPSNAQYQYTLQADNLEELRAWEPKIRQALTQIKSLVDVNTDAQDKGQQTALVFDR 711 Query: 721 IAARRLGLEMTNIDDFLNNAFSQRQVATQYQALNQYYTILGLAPQYTQDPEVLKQLFVLN 780 A LG+ +ID+ LNNAF QRQV+T Y LNQY ++ APQY Q+PE L+ ++++ Sbjct: 712 DKAMALGITPKDIDNALNNAFGQRQVSTIYNPLNQYRVVMEAAPQYWQNPEGLRDIYLIT 771 Query: 781 SAGNAVPLSAFARLQSASAPLAVAHQNQSATTTIAFNLADGVSLQQAKAAIDAAVISLGL 840 ++G VPLS F+ + PLAV HQ Q A +T++FNLA G SL A I A+ +G+ Sbjct: 772 ASGAQVPLSTFSHYGPTNTPLAVNHQGQFAASTLSFNLAPGASLSAATQQIQDAMNRIGV 831 Query: 841 PGSIHGGMQGTAQAFVAMASAMPWLILAALLAVYIVLGMLYESWIHPITILSTLPSAGVG 900 P ++HG QGTA+AF S+ P LIL AL+ +YIVLG+LYES++HPITILSTLPSAGVG Sbjct: 832 PTTVHGSFQGTARAFQDSLSSQPVLILFALITIYIVLGVLYESYVHPITILSTLPSAGVG 891 Query: 901 ALLLLLATHTQFTVIALIGVLLLIGIVKKNAILMVDFALHVERQHDWAAERAILEACRMR 960 ALL L+ T T F+VIALIGV+LLIGIVKKNAI+M+DFAL ER + AI AC +R Sbjct: 892 ALLALIVTDTDFSVIALIGVILLIGIVKKNAIMMIDFALEAERSQGMSPADAIFHACVLR 951 Query: 961 LRPILMTTMAAFFGALPMVLQTGGDAALRRPLGLTICGGLALSQLLTLYTTPVVYVYMD 1019 RPILMTTMAA GALP+ L G A LR+PLG++I GGL +SQ+LTLYTTPVVY+ +D Sbjct: 952 FRPILMTTMAALLGALPLALGHGDGAELRQPLGISIVGGLLVSQILTLYTTPVVYLALD 1010 >YPO2849 [V] COG0841 Cation/multidrug efflux pump Ype Yersinia pestis Length = 1024 Score = 1112 bits (2877), Expect = 0.0, Method: Compositional matrix adjust. Identities = 563/1015 (55%), Positives = 746/1015 (73%), Gaps = 10/1015 (0%) Query: 7 FILRPVATLLLSLALTLLGALAYRMLPVAPLPQVDFPTIMVTASLAGASPETMAATIAAP 66 FI RPVAT LL+LA+TL G + + +LPV+PLPQVD+P IMV+AS+ GA PETMA+++A P Sbjct: 7 FIQRPVATTLLTLAITLSGIIGFSLLPVSPLPQVDYPVIMVSASMPGADPETMASSVATP 66 Query: 67 LERAMGQIAGITEMTSSSSQGSTNVIVQFDLERDIDGAARDVQAAINAARSLLPSSLKTL 126 LERA+G+IAG+ EMTS+SS GST +I+QFDL RDI+GAARDVQAA+NAA+SLLPS + + Sbjct: 67 LERALGRIAGVNEMTSTSSLGSTRIILQFDLNRDINGAARDVQAALNAAQSLLPSGMPSR 126 Query: 127 PTYRKANPADAPILLLALTSKTVDKGKLYDLASSKLQQTIAQVQGVGQVSLMGSALPAVR 186 PTYRK NP+DAPI+++ LTS T +G+LYD AS+KL Q IAQ +GV V++ GS+LPAVR Sbjct: 127 PTYRKMNPSDAPIMIMTLTSDTFSQGQLYDYASTKLAQKIAQTEGVSDVTVGGSSLPAVR 186 Query: 187 IELQPQQLSHYGISLDTVRQVVANATTNLPKGELQGEGLHWWVDANGQLTKASDYTNLVV 246 +EL P L + G+SLD VRQ ++ A P+G + HW V AN ++ A Y L+V Sbjct: 187 VELNPSALFNQGVSLDAVRQAISAANVRRPQGSVDAAETHWQVQANDEIKTAEGYRPLIV 246 Query: 247 SYQNGAAVKLSDVARVYDSVQDQYVAGYFNDSPSVMMGITRSSGANMLATIDAIKAQLPI 306 Y NG+ V+L DVA V DSVQD AG P+V++ I+R GAN++AT+D I+A+LP Sbjct: 247 HYNNGSPVRLQDVANVIDSVQDVRNAGMSAGQPAVLLVISREPGANIIATVDRIRAELPA 306 Query: 307 MQKMLPKEVQLSLAMDRSPSIRGSLRETELTLLISTLLVIAVVFLFLRNARAVLIPAVAL 366 ++ +P +QL++A DRSP+IR SL E E +L+I+ LVI VVF+FLR+ RA LIPAVA+ Sbjct: 307 LRASIPASIQLNIAQDRSPTIRASLDEVERSLVIAVALVILVVFIFLRSGRATLIPAVAV 366 Query: 367 PISLIGTCAAMYLLGYSLDTLSLMALIIATGFVVDDAIVVLENISRHLEEGAPPLKAALD 426 P+SLIGT AAMYL G+SL+ LSLMAL IATGFVVDDAIVVLENISRHLE G P AAL Sbjct: 367 PVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENISRHLEAGVKPKVAALR 426 Query: 427 GSKEVGFTVLSMTASLIAVFLPILLMGSIVGRLFREFAVTLSVSLVLSMIVSLTLTPMLC 486 G +EVGFTVLSM+ SL+AVF+P+LLM + GRLFREFAVTLSV++ +S+++SLTLTPM+C Sbjct: 427 GVREVGFTVLSMSISLVAVFIPLLLMAGLPGRLFREFAVTLSVAIGISLVISLTLTPMMC 486 Query: 487 SRLLRAHKHDASGAPVQPNVFYRAIERVLNAVSDGYASSLEWVMRHKRLTLLSLVLTVAL 546 + LLR+H P R +VL A+ GY SL W + H R ++ L+ T+AL Sbjct: 487 AWLLRSH-------PKGQQQRIRGFGKVLLAIQQGYGRSLNWALSHTRWVMVVLLSTIAL 539 Query: 547 NLFLFTAVQKGFFPDQDTGMLMGQMRADQAASFQSVHPQLLAFSRLIQSDPDVASVMAST 606 N++L+ ++ K FFP+QDTG +MG ++ADQ+ SFQS+ +L F +++ +DP V SV T Sbjct: 540 NVWLYISIPKTFFPEQDTGRMMGFIQADQSISFQSMQQKLKDFMQIVGADPAVDSVTGFT 599 Query: 607 GGGAFGSRNTANFFVSLKDSSQRKSTATEIANRLTRKASGVPGASLFLMAGQDLRMGGRS 666 GG N+ + F+SLK S+R+ TA ++ RL K + PGA+LFL + QD+R+GGR Sbjct: 600 GG---SRTNSGSMFISLKPLSERQETAQQVITRLRGKLAKEPGANLFLSSVQDIRVGGRH 656 Query: 667 ANATYQYSLQSDSLDTLREWSPKVYAVLRKLPELTSVDTDAQSGGQAVKLVIDRIAARRL 726 +NA YQ++L +D L LREW PKV A L KLP+L V++D Q G + L DR RL Sbjct: 657 SNAAYQFTLLADDLAALREWEPKVRAALAKLPQLADVNSDQQDKGAEMALTYDRETMARL 716 Query: 727 GLEMTNIDDFLNNAFSQRQVATQYQALNQYYTILGLAPQYTQDPEVLKQLFVLNSAGNAV 786 G++++ + LNNAF QRQ++T YQ LNQY ++ +AP+YTQD L ++FV+NS G ++ Sbjct: 717 GIDVSEANALLNNAFGQRQISTIYQPLNQYKVVMEVAPEYTQDVSSLDKMFVINSNGQSI 776 Query: 787 PLSAFARLQSASAPLAVAHQNQSATTTIAFNLADGVSLQQAKAAIDAAVISLGLPGSIHG 846 PLS FA+ Q A+APLAV HQ SA +TI+FNL DG SL +A AA++ A+ LG+P ++ G Sbjct: 777 PLSYFAKWQPANAPLAVNHQGLSAASTISFNLPDGGSLSEATAAVERAMTELGVPSTVRG 836 Query: 847 GMQGTAQAFVAMASAMPWLILAALLAVYIVLGMLYESWIHPITILSTLPSAGVGALLLLL 906 GTAQ F + WLI+AA+ VYIVLG+LYES++HP+TILSTLPSAGVGALL L Sbjct: 837 AFAGTAQVFQETLKSQLWLIMAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALE 896 Query: 907 ATHTQFTVIALIGVLLLIGIVKKNAILMVDFALHVERQHDWAAERAILEACRMRLRPILM 966 F++IALIG++LLIGIVKKNAI+MVDFAL +R + +A AI +A +R RPI+M Sbjct: 897 LFDAPFSLIALIGIMLLIGIVKKNAIMMVDFALDAQRNGNISAREAIFQASLLRFRPIIM 956 Query: 967 TTMAAFFGALPMVLQTGGDAALRRPLGLTICGGLALSQLLTLYTTPVVYVYMDRM 1021 TT+AA FGALP+VL +G A LR+PLG+TI GGL +SQLLTLYTTPV+Y+Y DR+ Sbjct: 957 TTLAALFGALPLVLSSGDGAELRQPLGITIVGGLVVSQLLTLYTTPVIYLYFDRL 1011 >yegO [V] COG0841 Cation/multidrug efflux pump Eco Escherichia coli K12 Length = 1025 Score = 1104 bits (2856), Expect = 0.0, Method: Compositional matrix adjust. Identities = 576/1033 (55%), Positives = 762/1033 (73%), Gaps = 17/1033 (1%) Query: 7 FILRPVATLLLSLALTLLGALAYRMLPVAPLPQVDFPTIMVTASLAGASPETMAATIAAP 66 FI RPVAT+LLS+A+TL G L +RMLPVAPLPQVDFP I+V+ASL GASPETMA+++A P Sbjct: 7 FIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIIVSASLPGASPETMASSVATP 66 Query: 67 LERAMGQIAGITEMTSSSSQGSTNVIVQFDLERDIDGAARDVQAAINAARSLLPSSLKTL 126 LER++G+IAG++EMTSSSS GST +I+QFD +RDI+GAARDVQAAINAA+SLLPS + + Sbjct: 67 LERSLGRIAGVSEMTSSSSLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSR 126 Query: 127 PTYRKANPADAPILLLALTSKTVDKGKLYDLASSKLQQTIAQVQGVGQVSLMGSALPAVR 186 PTYRKANP+DAPI++L LTS T +G+LYD AS++L TI+Q+ GVG V + GS+LPAVR Sbjct: 127 PTYRKANPSDAPIMILTLTSDTYSQGELYDFASTQLAPTISQIDGVGDVDVGGSSLPAVR 186 Query: 187 IELQPQQLSHYGISLDTVRQVVANATTNLPKGELQGEGLHWWVDANGQLTKASDYTNLVV 246 + L PQ L + G+SLD VR V+NA P+G L+ W + N +L A++Y L++ Sbjct: 187 VGLNPQALFNQGVSLDDVRTAVSNANVRKPQGALEDGTHRWQIQTNDELKTAAEYQPLII 246 Query: 247 SYQNGAAVKLSDVARVYDSVQDQYVAGYFNDSPSVMMGITRSSGANMLATIDAIKAQLPI 306 Y NG AV+L DVA V DSVQD AG N P++++ I + AN++ T+D+I+A+LP Sbjct: 247 HYNNGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDSIRAKLPE 306 Query: 307 MQKMLPKEVQLSLAMDRSPSIRGSLRETELTLLISTLLVIAVVFLFLRNARAVLIPAVAL 366 +Q+ +P + L +A DRSP+IR SL E E TL+IS LVI VVFLFLR+ RA +IPAV++ Sbjct: 307 LQETIPAAIDLQIAQDRSPTIRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVSV 366 Query: 367 PISLIGTCAAMYLLGYSLDTLSLMALIIATGFVVDDAIVVLENISRHLEEGAPPLKAALD 426 P+SLIGT AAMYL G+SL+ LSLMAL IATGFVVDDAIVVLENI+RHLE G PL+AAL Sbjct: 367 PVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENIARHLEAGMKPLQAALQ 426 Query: 427 GSKEVGFTVLSMTASLIAVFLPILLMGSIVGRLFREFAVTLSVSLVLSMIVSLTLTPMLC 486 G++EVGFTVLSM+ SL+AVFLP+LLMG + GRL REFAVTLSV++ +S++VSLTLTPM+C Sbjct: 427 GTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLLVSLTLTPMMC 486 Query: 487 SRLLRAHKHDASGAPVQPNVFYRAIERVLNAVSDGYASSLEWVMRHKRLTLLSLVLTVAL 546 +L+A K P + R R+L A+ GY SL+WV+ H RL + L+ T+AL Sbjct: 487 GWMLKASK------PREQKRL-RGFGRMLVALQQGYGKSLKWVLNHTRLVGVVLLGTIAL 539 Query: 547 NLFLFTAVQKGFFPDQDTGMLMGQMRADQAASFQSVHPQLLAFSRLIQSDPDVASVMAST 606 N++L+ ++ K FFP+QDTG+LMG ++ADQ+ SFQ++ +L F ++I+ DP V +V T Sbjct: 540 NIWLYISIPKTFFPEQDTGVLMGGIQADQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFT 599 Query: 607 GGGAFGSR-NTANFFVSLKDSSQRKSTATEIANRLTRKASGVPGASLFLMAGQDLRMGGR 665 G GSR N+ F++LK +R TA +I +RL K + PGA+LFLMA QD+R+GGR Sbjct: 600 G----GSRVNSGMMFITLKPRDERSETAQQIIDRLRVKLAKEPGANLFLMAVQDIRVGGR 655 Query: 666 SANATYQYSLQSDSLDTLREWSPKVYAVLRKLPELTSVDTDAQSGGQAVKLVIDRIAARR 725 +NA+YQY+L SD L LREW PK+ L LPEL V++D Q G + LV DR R Sbjct: 656 QSNASYQYTLLSDDLAALREWEPKIRKKLATLPELADVNSDQQDNGAEMNLVYDRDTMAR 715 Query: 726 LGLEMTNIDDFLNNAFSQRQVATQYQALNQYYTILGLAPQYTQDPEVLKQLFVLNSAGNA 785 LG+++ + LNNAF QRQ++T YQ +NQY ++ + P+YTQD L+++FV+N+ G A Sbjct: 716 LGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQDISALEKMFVINNEGKA 775 Query: 786 VPLSAFARLQSASAPLAVAHQNQSATTTIAFNLADGVSLQQAKAAIDAAVISLGLPGSIH 845 +PLS FA+ Q A+APL+V HQ SA +TI+FNL G SL A AAID A+ LG+P ++ Sbjct: 776 IPLSYFAKWQPANAPLSVNHQGLSAASTISFNLPTGKSLSDASAAIDRAMTQLGVPSTVR 835 Query: 846 GGMQGTAQAFVAMASAMPWLILAALLAVYIVLGMLYESWIHPITILSTLPSAGVGALLLL 905 G GTAQ F ++ LI+AA+ VYIVLG+LYES++HP+TILSTLPSAGVGALL L Sbjct: 836 GSFAGTAQVFQETMNSQVILIIAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLAL 895 Query: 906 LATHTQFTVIALIGVLLLIGIVKKNAILMVDFALHVERQHDWAAERAILEACRMRLRPIL 965 + F++IALIG++LLIGIVKKNAI+MVDFAL +R + + AI +AC +R RPI+ Sbjct: 896 ELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRHGNLTPQEAIFQACLLRFRPIM 955 Query: 966 MTTMAAFFGALPMVLQTGGDAALRRPLGLTICGGLALSQLLTLYTTPVVYVYMDRMGSAA 1025 MTT+AA FGALP+VL G + LR+PLG+TI GGL +SQLLTLYTTPVVY++ DR+ Sbjct: 956 MTTLAALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRL---- 1011 Query: 1026 KRLWRRRRPRPSV 1038 RL R+P+ +V Sbjct: 1012 -RLRFSRKPKQTV 1023 >ECs2884 [V] COG0841 Cation/multidrug efflux pump Ecs Escherichia coli O157:H7 Length = 1025 Score = 1103 bits (2854), Expect = 0.0, Method: Compositional matrix adjust. Identities = 576/1033 (55%), Positives = 761/1033 (73%), Gaps = 17/1033 (1%) Query: 7 FILRPVATLLLSLALTLLGALAYRMLPVAPLPQVDFPTIMVTASLAGASPETMAATIAAP 66 FI RPVAT+LLS+A+TL G L +RMLPVAPLPQVDFP IMV+ASL GASPETMA+++A P Sbjct: 7 FIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIMVSASLPGASPETMASSVATP 66 Query: 67 LERAMGQIAGITEMTSSSSQGSTNVIVQFDLERDIDGAARDVQAAINAARSLLPSSLKTL 126 LER++G+IAG++EMTSSSS GST +I+QFD +RDI+GAARDVQAAINAA+SLLPS + + Sbjct: 67 LERSLGRIAGVSEMTSSSSLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSR 126 Query: 127 PTYRKANPADAPILLLALTSKTVDKGKLYDLASSKLQQTIAQVQGVGQVSLMGSALPAVR 186 PTYRKANP+DAPI++L LTS T +G+LYD AS++L TI+Q+ GVG V + GS+LPAVR Sbjct: 127 PTYRKANPSDAPIMILTLTSDTYSQGELYDFASTQLAPTISQIDGVGDVDVGGSSLPAVR 186 Query: 187 IELQPQQLSHYGISLDTVRQVVANATTNLPKGELQGEGLHWWVDANGQLTKASDYTNLVV 246 + L PQ L + G+SLD VR ++NA P+G L+ W + N +L A++Y L++ Sbjct: 187 VGLNPQALFNQGVSLDDVRTAISNANVRKPQGALEDGTHRWQIQTNDELKTAAEYQPLII 246 Query: 247 SYQNGAAVKLSDVARVYDSVQDQYVAGYFNDSPSVMMGITRSSGANMLATIDAIKAQLPI 306 Y NG AV+L DVA V DSVQD AG N P++++ I + AN++ T+D+I+A+LP Sbjct: 247 HYNNGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDSIRAKLPE 306 Query: 307 MQKMLPKEVQLSLAMDRSPSIRGSLRETELTLLISTLLVIAVVFLFLRNARAVLIPAVAL 366 +Q+ +P + L +A DRSP+IR SL E E TL+IS LVI VVFLFLR+ RA +IPAVA+ Sbjct: 307 LQETIPAAIDLQIAQDRSPTIRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVAV 366 Query: 367 PISLIGTCAAMYLLGYSLDTLSLMALIIATGFVVDDAIVVLENISRHLEEGAPPLKAALD 426 P+SLIGT AAMYL G+SL+ LSLMAL IATGFVVDDAIVVLENI+RHLE G PL+AAL Sbjct: 367 PVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENIARHLEAGMKPLQAALQ 426 Query: 427 GSKEVGFTVLSMTASLIAVFLPILLMGSIVGRLFREFAVTLSVSLVLSMIVSLTLTPMLC 486 G++EVGFTVLSM+ SL+AVFLP+LLMG + GRL REFAVTLSV++ +S++VSLTLTPM+C Sbjct: 427 GTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLLVSLTLTPMMC 486 Query: 487 SRLLRAHKHDASGAPVQPNVFYRAIERVLNAVSDGYASSLEWVMRHKRLTLLSLVLTVAL 546 +L+A K P + R R+L A+ GY SL+WV+ H RL + L+ T+AL Sbjct: 487 GWMLKASK------PREQKRL-RGFGRMLVALQQGYGKSLKWVLNHTRLVGMVLLGTIAL 539 Query: 547 NLFLFTAVQKGFFPDQDTGMLMGQMRADQAASFQSVHPQLLAFSRLIQSDPDVASVMAST 606 N++L+ ++ K FFP+QDTG+LMG ++ADQ+ SFQ++ +L F ++I+ DP V +V T Sbjct: 540 NIWLYISIPKTFFPEQDTGVLMGGIQADQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFT 599 Query: 607 GGGAFGSR-NTANFFVSLKDSSQRKSTATEIANRLTRKASGVPGASLFLMAGQDLRMGGR 665 G GSR N+ F++LK +R TA +I +RL K + PGA+LFLMA QD+R+GGR Sbjct: 600 G----GSRVNSGMMFITLKPRDERSETAQQIIDRLRVKLAKEPGANLFLMAVQDIRVGGR 655 Query: 666 SANATYQYSLQSDSLDTLREWSPKVYAVLRKLPELTSVDTDAQSGGQAVKLVIDRIAARR 725 +NA+YQY+L SD L LREW PK+ L LPEL V++D Q G + LV DR R Sbjct: 656 QSNASYQYTLLSDDLAALREWEPKIRKKLATLPELADVNSDQQDNGAEMNLVYDRDTMAR 715 Query: 726 LGLEMTNIDDFLNNAFSQRQVATQYQALNQYYTILGLAPQYTQDPEVLKQLFVLNSAGNA 785 LG+++ + LNNAF QRQ++T YQ +NQY ++ + P+YTQD L+++FV+N+ G A Sbjct: 716 LGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQDISALEKMFVINNEGKA 775 Query: 786 VPLSAFARLQSASAPLAVAHQNQSATTTIAFNLADGVSLQQAKAAIDAAVISLGLPGSIH 845 +PLS FA+ Q A+APL+V HQ SA +TI+FNL G SL A AAID A+ LG+P ++ Sbjct: 776 IPLSYFAKWQPANAPLSVNHQGLSAASTISFNLPTGKSLSDASAAIDRAMTQLGVPSTVR 835 Query: 846 GGMQGTAQAFVAMASAMPWLILAALLAVYIVLGMLYESWIHPITILSTLPSAGVGALLLL 905 G GTAQ F ++ LI+AA+ VYIVLG+LYES++HP+TILSTLPSAGVGALL L Sbjct: 836 GSFAGTAQVFQETMNSQVILIIAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLAL 895 Query: 906 LATHTQFTVIALIGVLLLIGIVKKNAILMVDFALHVERQHDWAAERAILEACRMRLRPIL 965 + F++IALIG++LLIGIVKKNAI+MVDFAL +R + + AI +AC +R RPI+ Sbjct: 896 ELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRHGNLTPQEAIFQACLLRFRPIM 955 Query: 966 MTTMAAFFGALPMVLQTGGDAALRRPLGLTICGGLALSQLLTLYTTPVVYVYMDRMGSAA 1025 MTT+AA FGALP+VL G + LR+PLG+TI GGL +SQLLTLYTTPVVY++ DR+ Sbjct: 956 MTTLAALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRL---- 1011 Query: 1026 KRLWRRRRPRPSV 1038 RL R+ + +V Sbjct: 1012 -RLRFSRKSKQTV 1023 >ZyegO [V] COG0841 Cation/multidrug efflux pump EcZ Escherichia coli O157:H7 EDL933 Length = 1025 Score = 1097 bits (2837), Expect = 0.0, Method: Compositional matrix adjust. Identities = 574/1033 (55%), Positives = 758/1033 (73%), Gaps = 17/1033 (1%) Query: 7 FILRPVATLLLSLALTLLGALAYRMLPVAPLPQVDFPTIMVTASLAGASPETMAATIAAP 66 FI RPVAT+LLS+A+TL G L +RMLPVAPLPQVDFP IMV+ASL GASPETMA+++A P Sbjct: 7 FIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIMVSASLPGASPETMASSVATP 66 Query: 67 LERAMGQIAGITEMTSSSSQGSTNVIVQFDLERDIDGAARDVQAAINAARSLLPSSLKTL 126 LER++G+IAG++EMTSSSS GST +I+QFD RDI+ AARDV AAINAA+SLLPS + + Sbjct: 67 LERSLGRIAGVSEMTSSSSLGSTRIILQFDFXRDINXAARDVXAAINAAQSLLPSGMPSR 126 Query: 127 PTYRKANPADAPILLLALTSKTVDKGKLYDLASSKLQQTIAQVQGVGQVSLMGSALPAVR 186 PTYRKANP+DAPI++L LTS T +G+LYD AS++L TI+Q+ GVG V + GS+LPAVR Sbjct: 127 PTYRKANPSDAPIMILTLTSDTYSQGELYDFASTQLAPTISQIDGVGDVDVGGSSLPAVR 186 Query: 187 IELQPQQLSHYGISLDTVRQVVANATTNLPKGELQGEGLHWWVDANGQLTKASDYTNLVV 246 + L PQ L + G+SLD VR ++NA P+G L+ W + N +L A++Y L++ Sbjct: 187 VGLNPQALFNQGVSLDDVRTAISNANVRKPQGALEDGTHRWQIQTNDELKTAAEYQPLII 246 Query: 247 SYQNGAAVKLSDVARVYDSVQDQYVAGYFNDSPSVMMGITRSSGANMLATIDAIKAQLPI 306 Y NG AV+L DVA V DSVQD AG N P++++ I + AN++ T+D+I+A+LP Sbjct: 247 HYNNGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDSIRAKLPE 306 Query: 307 MQKMLPKEVQLSLAMDRSPSIRGSLRETELTLLISTLLVIAVVFLFLRNARAVLIPAVAL 366 +Q+ +P + L +A DRSP+IR SL E E TL+IS LVI VVFLFLR+ RA +IPAVA+ Sbjct: 307 LQETIPAAIDLQIAQDRSPTIRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVAV 366 Query: 367 PISLIGTCAAMYLLGYSLDTLSLMALIIATGFVVDDAIVVLENISRHLEEGAPPLKAALD 426 P+SLIGT AAMYL G+SL+ LSLMAL IATGFVVDDAIVVLENI+RHLE G PL+AAL Sbjct: 367 PVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENIARHLEAGMKPLQAALQ 426 Query: 427 GSKEVGFTVLSMTASLIAVFLPILLMGSIVGRLFREFAVTLSVSLVLSMIVSLTLTPMLC 486 G++EVGFTVLSM+ SL+AVFLP+LLMG + GRL REFAVTLSV++ +S++VSLTLTPM+C Sbjct: 427 GTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLLVSLTLTPMMC 486 Query: 487 SRLLRAHKHDASGAPVQPNVFYRAIERVLNAVSDGYASSLEWVMRHKRLTLLSLVLTVAL 546 +L+A K P + R R+L A+ GY SL+WV+ H RL + L+ T+AL Sbjct: 487 GWMLKASK------PREQKRL-RGFGRMLVALQQGYGKSLKWVLNHTRLVGMVLLGTIAL 539 Query: 547 NLFLFTAVQKGFFPDQDTGMLMGQMRADQAASFQSVHPQLLAFSRLIQSDPDVASVMAST 606 N++L+ ++ K FFP+QDTG+LMG ++ADQ+ SFQ++ +L F ++I+ DP V +V T Sbjct: 540 NIWLYISIPKTFFPEQDTGVLMGGIQADQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFT 599 Query: 607 GGGAFGSR-NTANFFVSLKDSSQRKSTATEIANRLTRKASGVPGASLFLMAGQDLRMGGR 665 G GSR N+ F++LK +R TA +I +RL K + PGA+LFLMA QD+R+GGR Sbjct: 600 G----GSRVNSGMMFITLKPRDERSETAQQIIDRLRVKLAKEPGANLFLMAVQDIRVGGR 655 Query: 666 SANATYQYSLQSDSLDTLREWSPKVYAVLRKLPELTSVDTDAQSGGQAVKLVIDRIAARR 725 +NA+YQY+L SD L LREW PK+ L LPEL V++D Q G + LV DR R Sbjct: 656 QSNASYQYTLLSDDLAALREWEPKIRKKLATLPELADVNSDQQDNGAEMNLVYDRDTMAR 715 Query: 726 LGLEMTNIDDFLNNAFSQRQVATQYQALNQYYTILGLAPQYTQDPEVLKQLFVLNSAGNA 785 LG+++ + LNNAF QRQ++T YQ +NQY ++ + P+YTQD L+++FV+N+ G A Sbjct: 716 LGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQDISALEKMFVINNEGKA 775 Query: 786 VPLSAFARLQSASAPLAVAHQNQSATTTIAFNLADGVSLQQAKAAIDAAVISLGLPGSIH 845 +PLS FA+ Q A+APL+V HQ SA +TI+FNL G SL A AAID A+ LG+P ++ Sbjct: 776 IPLSYFAKWQPANAPLSVNHQGLSAASTISFNLPTGKSLSDASAAIDRAMTQLGVPSTVR 835 Query: 846 GGMQGTAQAFVAMASAMPWLILAALLAVYIVLGMLYESWIHPITILSTLPSAGVGALLLL 905 G GTAQ F ++ LI+AA+ VYIVLG+LYES++HP+TILSTLPSAGVGALL L Sbjct: 836 GSFAGTAQVFQETMNSQVILIIAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLAL 895 Query: 906 LATHTQFTVIALIGVLLLIGIVKKNAILMVDFALHVERQHDWAAERAILEACRMRLRPIL 965 + F++IALIG++LLIGIVKKNAI+MVDFAL +R + + AI +AC +R RPI+ Sbjct: 896 ELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRHGNLTPQEAIFQACLLRFRPIM 955 Query: 966 MTTMAAFFGALPMVLQTGGDAALRRPLGLTICGGLALSQLLTLYTTPVVYVYMDRMGSAA 1025 MTT+AA FGALP+VL G + LR+PLG+TI GGL +SQLLTLYTTPVVY++ DR+ Sbjct: 956 MTTLAALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRL---- 1011 Query: 1026 KRLWRRRRPRPSV 1038 RL R+ + +V Sbjct: 1012 -RLRFSRKSKQTV 1023