BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.2650.p (365 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value purR [K] COG1609 Transcriptional regulators Eco Escherichia coli... 159 7e-39 ZpurR [K] COG1609 Transcriptional regulators EcZ Escherichia col... 159 7e-39 ECs2367 [K] COG1609 Transcriptional regulators Ecs Escherichia c... 159 7e-39 STM1430 [K] COG1609 Transcriptional regulators Sty Salmonella ty... 155 1e-37 PA1949 [K] COG1609 Transcriptional regulators Pae Pseudomonas ae... 154 3e-37 >purR [K] COG1609 Transcriptional regulators Eco Escherichia coli K12 Length = 341 Score = 159 bits (403), Expect = 7e-39, Method: Compositional matrix adjust. Identities = 102/330 (30%), Positives = 170/330 (51%), Gaps = 27/330 (8%) Query: 5 TIKDVAKAAGVSFQTVSLVLNHPEKVAPKTRELVQSAIDALNFIPNVAARSLRNISTKTL 64 TIKDVAK A VS TVS V+N VA +TR V +AI L++ P+ ARSL+ TK++ Sbjct: 3 TIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSI 62 Query: 65 ACVMFNGSSYDERSERTQDTHYHNVVQTLTRAADRAGYTLLQRNLMREDEASLVYVRDLF 124 + + ++ ++ +++ + + + GYTL+ N E Y+ + Sbjct: 63 GLL----------ATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYL-SMM 111 Query: 125 LAGRIDGMIAMVNRAGNPVVAELHRLGY-PCVV--YGMADP-VCHHVVQSDRQAGLAVVE 180 R+DG++ M + P++A L + P VV +G A V+ + + G Sbjct: 112 AQKRVDGLLVMCSEYPEPLLAMLEEYRHIPMVVMDWGEAKADFTDAVIDNAFEGGYMAGR 171 Query: 181 HLYRTGCRKIALVTGPQKDHLPGKSREDGVPTSSEARYFGYLDGLEKCGLTPHPEWIVTG 240 +L G R+I ++ GP + + + R G++ +E+ + WIV G Sbjct: 172 YLIERGHREIGVIPGPLERN------------TGAGRLAGFMKAMEEAMIKVPESWIVQG 219 Query: 241 DWSLESGYRAAAQLCHQAERPDAIFLGNDRMALGALKALYDLGVKVPHEISVVGFDNMRY 300 D+ ESGYRA Q+ Q RP A+F G D MA+GAL A ++G++VP ++S++G+DN+R Sbjct: 220 DFEPESGYRAMQQILSQPHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDNVRN 279 Query: 301 DDFSIPSLTSVDAPMLDMCEFAVRLLLEHI 330 + P+LT++ P + E A +LL+ I Sbjct: 280 ARYFTPALTTIHQPKDSLGETAFNMLLDRI 309 >ZpurR [K] COG1609 Transcriptional regulators EcZ Escherichia coli O157:H7 EDL933 Length = 341 Score = 159 bits (403), Expect = 7e-39, Method: Compositional matrix adjust. Identities = 102/330 (30%), Positives = 170/330 (51%), Gaps = 27/330 (8%) Query: 5 TIKDVAKAAGVSFQTVSLVLNHPEKVAPKTRELVQSAIDALNFIPNVAARSLRNISTKTL 64 TIKDVAK A VS TVS V+N VA +TR V +AI L++ P+ ARSL+ TK++ Sbjct: 3 TIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSI 62 Query: 65 ACVMFNGSSYDERSERTQDTHYHNVVQTLTRAADRAGYTLLQRNLMREDEASLVYVRDLF 124 + + ++ ++ +++ + + + GYTL+ N E Y+ + Sbjct: 63 GLL----------ATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYL-SMM 111 Query: 125 LAGRIDGMIAMVNRAGNPVVAELHRLGY-PCVV--YGMADP-VCHHVVQSDRQAGLAVVE 180 R+DG++ M + P++A L + P VV +G A V+ + + G Sbjct: 112 AQKRVDGLLVMCSEYPEPLLAMLEEYRHIPMVVMDWGEAKADFTDAVIDNAFEGGYMAGR 171 Query: 181 HLYRTGCRKIALVTGPQKDHLPGKSREDGVPTSSEARYFGYLDGLEKCGLTPHPEWIVTG 240 +L G R+I ++ GP + + + R G++ +E+ + WIV G Sbjct: 172 YLIERGHREIGVIPGPLERN------------TGAGRLAGFMKAMEEAMIKVPESWIVQG 219 Query: 241 DWSLESGYRAAAQLCHQAERPDAIFLGNDRMALGALKALYDLGVKVPHEISVVGFDNMRY 300 D+ ESGYRA Q+ Q RP A+F G D MA+GAL A ++G++VP ++S++G+DN+R Sbjct: 220 DFEPESGYRAMQQILSQPHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDNVRN 279 Query: 301 DDFSIPSLTSVDAPMLDMCEFAVRLLLEHI 330 + P+LT++ P + E A +LL+ I Sbjct: 280 ARYFTPALTTIHQPKDSLGETAFNMLLDRI 309 >ECs2367 [K] COG1609 Transcriptional regulators Ecs Escherichia coli O157:H7 Length = 341 Score = 159 bits (403), Expect = 7e-39, Method: Compositional matrix adjust. Identities = 102/330 (30%), Positives = 170/330 (51%), Gaps = 27/330 (8%) Query: 5 TIKDVAKAAGVSFQTVSLVLNHPEKVAPKTRELVQSAIDALNFIPNVAARSLRNISTKTL 64 TIKDVAK A VS TVS V+N VA +TR V +AI L++ P+ ARSL+ TK++ Sbjct: 3 TIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSI 62 Query: 65 ACVMFNGSSYDERSERTQDTHYHNVVQTLTRAADRAGYTLLQRNLMREDEASLVYVRDLF 124 + + ++ ++ +++ + + + GYTL+ N E Y+ + Sbjct: 63 GLL----------ATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYL-SMM 111 Query: 125 LAGRIDGMIAMVNRAGNPVVAELHRLGY-PCVV--YGMADP-VCHHVVQSDRQAGLAVVE 180 R+DG++ M + P++A L + P VV +G A V+ + + G Sbjct: 112 AQKRVDGLLVMCSEYPEPLLAMLEEYRHIPMVVMDWGEAKADFTDAVIDNAFEGGYMAGR 171 Query: 181 HLYRTGCRKIALVTGPQKDHLPGKSREDGVPTSSEARYFGYLDGLEKCGLTPHPEWIVTG 240 +L G R+I ++ GP + + + R G++ +E+ + WIV G Sbjct: 172 YLIERGHREIGVIPGPLERN------------TGAGRLAGFMKAMEEAMIKVPESWIVQG 219 Query: 241 DWSLESGYRAAAQLCHQAERPDAIFLGNDRMALGALKALYDLGVKVPHEISVVGFDNMRY 300 D+ ESGYRA Q+ Q RP A+F G D MA+GAL A ++G++VP ++S++G+DN+R Sbjct: 220 DFEPESGYRAMQQILSQPHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDNVRN 279 Query: 301 DDFSIPSLTSVDAPMLDMCEFAVRLLLEHI 330 + P+LT++ P + E A +LL+ I Sbjct: 280 ARYFTPALTTIHQPKDSLGETAFNMLLDRI 309 >STM1430 [K] COG1609 Transcriptional regulators Sty Salmonella typhimurium LT2 Length = 341 Score = 155 bits (393), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 103/330 (31%), Positives = 168/330 (50%), Gaps = 27/330 (8%) Query: 5 TIKDVAKAAGVSFQTVSLVLNHPEKVAPKTRELVQSAIDALNFIPNVAARSLRNISTKTL 64 TIKDVAK A VS TVS V+N VA +TR V +AI L++ P+ ARSL+ TK++ Sbjct: 3 TIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSI 62 Query: 65 ACVMFNGSSYDERSERTQDTHYHNVVQTLTRAADRAGYTLLQRNLMREDEASLVYVRDLF 124 + + ++ ++ +++ + + + GYTL+ N E Y+ + Sbjct: 63 GLL----------ATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYL-SMM 111 Query: 125 LAGRIDGMIAMVNRAGNPVVAELHRLGY-PCVV--YGMADP-VCHHVVQSDRQAGLAVVE 180 R+DG++ M + P+++ L + P VV +G A V+ + G Sbjct: 112 AQKRVDGLLVMCSEYPEPLLSMLEEYRHIPMVVMDWGEAKADFTDTVIDNAFAGGYMAGR 171 Query: 181 HLYRTGCRKIALVTGPQKDHLPGKSREDGVPTSSEARYFGYLDGLEKCGLTPHPEWIVTG 240 +L G R I ++ GP + R G R G++ +E+ + WIV G Sbjct: 172 YLVERGHRDIGVIPGPLE-------RNTGA-----GRLAGFMKAMEEALINVPDNWIVQG 219 Query: 241 DWSLESGYRAAAQLCHQAERPDAIFLGNDRMALGALKALYDLGVKVPHEISVVGFDNMRY 300 D+ ESGY A Q+ Q+ RP A+F G D MA+GAL A ++G++VP ++SV+G+DN+R Sbjct: 220 DFEPESGYHAMQQILSQSHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSVIGYDNVRN 279 Query: 301 DDFSIPSLTSVDAPMLDMCEFAVRLLLEHI 330 + P+LT++ P + E A +LL+ I Sbjct: 280 ARYFTPALTTIHQPKDSLGETAFNMLLDRI 309 >PA1949 [K] COG1609 Transcriptional regulators Pae Pseudomonas aeruginosa Length = 337 Score = 154 bits (389), Expect = 3e-37, Method: Compositional matrix adjust. Identities = 113/363 (31%), Positives = 184/363 (50%), Gaps = 37/363 (10%) Query: 5 TIKDVAKAAGVSFQTVSLVLNHPEKVAPKTRELVQSAIDALNFIPNVAARSLRNISTKTL 64 T+KDVA AGVSF TVS V+N V+ R+ V+ AI L+++P+ ARSL+ +T + Sbjct: 3 TMKDVAAMAGVSFTTVSHVVNRTRPVSDAVRKKVEDAIAQLHYVPSAVARSLKVRTTSII 62 Query: 65 ACVMFNGSSYDERSERTQDTHYHNVVQTLTRAADRAGYTLLQRNLMREDEASLVYVRDLF 124 ++ N + + ++ + + + +R GY ++ N + Y+R + Sbjct: 63 GLLVPNST----------NPYFAELSRGIEDCCERNGYCVILCNSDDNPQKQANYLR-VL 111 Query: 125 LAGRIDGMIAMVNRAGNPVVAE-LHRLGYPCVVYGM-ADPVCHHVVQSDRQAGLAV-VEH 181 RIDG++ + + G+ +A+ L + P V+ + V VQ D + G + H Sbjct: 112 QEKRIDGLV-LASAGGDGALAKGLANMRTPTVIVDREVEGVEADRVQIDHEMGAYLATRH 170 Query: 182 LYRTGCRKIALVTGPQKDHLPGKSREDGVPTSSEARYFGYLDGLEKCGLTPHPEWIVTGD 241 L G R IA + GP + S R GY + K GL P+W++ + Sbjct: 171 LLELGHRDIACIGGPLSTKV------------STLRVEGYRRAMAKAGLEVRPQWLLESE 218 Query: 242 WSLESGYRAA-AQLCHQAERPDAIFLGNDRMALGALKALYDLGVKVPHEISVVGFDNMRY 300 +S GY AA L + ERP AI GND + +G L+A +L ++VPHE+SV+GFD++ Sbjct: 219 FSSPGGYHAALGLLGGEGERPTAIVAGNDMIGIGVLRAAAELNIRVPHELSVIGFDDIEL 278 Query: 301 DDFSIPSLTSVDAPMLDMCEFAVRLLLEHIGQRGQRKTDGGEPATLVQKVFSTHLVIRDS 360 F P+LT+V + + E A +LLL+ I +R EP + ++V + LV+R+S Sbjct: 279 SRFVFPALTTVGQSIRLLGEIAAQLLLQRIAER-------EEP--MQRRVVAPALVLRES 329 Query: 361 TRP 363 T P Sbjct: 330 TAP 332