BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.2641.p (354 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1782 [R] COG0354 Predicted aminomethyltransferase related to ... 286 3e-77 PA0759 [R] COG0354 Predicted aminomethyltransferase related to G... 159 9e-39 NMA1464 [R] COG0354 Predicted aminomethyltransferase related to ... 153 6e-37 NMB1024 [R] COG0354 Predicted aminomethyltransferase related to ... 152 1e-36 STM3048 [R] COG0354 Predicted aminomethyltransferase related to ... 126 9e-29 >RSc1782 [R] COG0354 Predicted aminomethyltransferase related to GcvT Rso Ralstonia solanacearum Length = 346 Score = 286 bits (733), Expect = 3e-77, Method: Compositional matrix adjust. Identities = 163/315 (51%), Positives = 194/315 (61%), Gaps = 10/315 (3%) Query: 44 SFMAPLTGLGLIAATGEEAASFLHGQLTNDVQHLDSNAARLAGYCSPKGRLLATLLIWRD 103 S + T L IA G +AA FLH QLTN V L AR AGYCSPKGRLLATLL+WR Sbjct: 28 SVLCAPTNLARIAVEGADAAEFLHNQLTNAVTGLGLAQARPAGYCSPKGRLLATLLLWRQ 87 Query: 104 AQTIYLQLPRSLQPAIQKRLQMFIMRAKAKLADAGTEYAVLGLVGPAAANALAEWFPVTP 163 A TI LQ + + PAI KRL MF++RAKAKL E+ + + GP AA+AL V P Sbjct: 88 ADTIVLQTDKLVAPAITKRLSMFVLRAKAKLRPMD-EFIAITVAGPDAADALRAAGAVLP 146 Query: 164 A--APYDKLDNSH------GSLIRMADAAGSARYQWIAPVDTLTAAWPKLAQHLKPTASL 215 APY S G+++R+ DA ARYQW+ + AW L+ L + Sbjct: 147 ESDAPYAVAQQSATVGQQVGAVVRLPDAGNRARYQWLVHAEHFQHAWKTLSSRLALIGTE 206 Query: 216 AWRLSDIRAGVPGIVAATQEQFVPQMINFELIGGVNFKKGCYPGQEIVARSQYLGKLKRR 275 W ++AGVP I +TQEQFVPQM+N ELIGGV+F+KGCYPGQE+VARSQY G LKRR Sbjct: 207 VWDWLGLQAGVPSITLSTQEQFVPQMVNLELIGGVDFRKGCYPGQEVVARSQYRGTLKRR 266 Query: 276 TMLATIDSAAAQAGQEVFAAADPGQPCGMVVNAEALDDGRALALVEMKLAAADDTVHLGA 335 A +D A AG EVF+AADP QPCGMVVNA DG LVE+KL A D +HL Sbjct: 267 MQRAHVD-APTSAGAEVFSAADPNQPCGMVVNAAMAPDGGTDLLVELKLDALDTVIHLAT 325 Query: 336 ADGPALHFHALPYEL 350 ADGP L LPY + Sbjct: 326 ADGPVLTLQRLPYAI 340 >PA0759 [R] COG0354 Predicted aminomethyltransferase related to GcvT Pae Pseudomonas aeruginosa Length = 314 Score = 159 bits (402), Expect = 9e-39, Method: Compositional matrix adjust. Identities = 110/308 (35%), Positives = 156/308 (50%), Gaps = 7/308 (2%) Query: 44 SFMAPLTGLGLIAATGEEAASFLHGQLTNDVQHLDSNAARLAGYCSPKGRLLATLLIWRD 103 +F PL G++A G +AA FL GQLT ++ +L+ + L G C+ KGRLL++ I + Sbjct: 5 AFHTPLVHEGILAVRGPDAAKFLQGQLTCNLAYLNDETSSLGGRCNIKGRLLSSFRILPE 64 Query: 104 AQTIYLQLPRSLQPAIQKRLQMFIMRAKAKLADAGTEYAVLGLVGPAAANALAEWFPVTP 163 + L + L A L+ + + +KA LAD + +GL A+ AL TP Sbjct: 65 GDGLLLAMAGELLEAQLADLKKYAVFSKASLADESAAWLRIGL--RDASEALRALGIDTP 122 Query: 164 AAPYDKLDNSHGSLIRMADAAGSARYQWIAPVDTLTAAWPKLAQHLKPTASLAWRLSDIR 223 A HG L +A A G R + P A L +H + W L +R Sbjct: 123 AESGRI--ARHGDL--LAVALGDGRVELWVPAQRAEAVLATLREHSREAPLDDWLLGQVR 178 Query: 224 AGVPGIVAATQEQFVPQMINFELIGGVNFKKGCYPGQEIVARSQYLGKLKRRTMLATIDS 283 AG+ + AT+E F+PQMIN + +GGV+FKKGCY GQEIVAR QYLG+LKRR +D+ Sbjct: 179 AGIGQVFGATRELFIPQMINLQAVGGVSFKKGCYTGQEIVARMQYLGRLKRRLYRLALDA 238 Query: 284 AAAQA-GQEVFAAADPGQPCGMVVNAEALDDGRALALVEMKLAAADDTVHLGAADGPALH 342 A G +F+ +V+ A ++ L V A AD + LG+A+G L Sbjct: 239 DEVPAPGTGLFSPVHSTSVGEVVLAARTPENSVELLAVLQDDAVADGRISLGSAEGAPLV 298 Query: 343 FHALPYEL 350 LPY L Sbjct: 299 LLNLPYTL 306 >NMA1464 [R] COG0354 Predicted aminomethyltransferase related to GcvT NmA Neisseria meningitidis Z2491 Length = 288 Score = 153 bits (387), Expect = 6e-37, Method: Compositional matrix adjust. Identities = 108/287 (37%), Positives = 163/287 (56%), Gaps = 33/287 (11%) Query: 52 LGLIAATGEEAASFLHGQLTNDVQHLDSNAARLAGYCSPKGRLLATLLIWRDAQTIYLQL 111 G++ +GE+ +FLHGQL+ND+ +L + A A Y +PKGR++A +++ + L + Sbjct: 9 FGVVRVSGEDRQTFLHGQLSNDINNLQTGQACYATYNTPKGRVIANMIVVNRGGDLLLIM 68 Query: 112 PRSLQPAIQKRLQMFIMRAKAKLADAGTEYAVLGLVGPAAANALAEWFPVTPAAPYDKLD 171 + L A KRL+MF++RAKA + + +YAV G A+A LA P A D Sbjct: 69 AQDLLEATVKRLRMFVLRAKA-VFEILEDYAV-GAELEASAEPLAAQEPNLAFAAQQDSD 126 Query: 172 NS------HGSLIRMADAAGSARYQWIAPVDTLTAAWPKLAQHLKPTASLAWRLSDIRAG 225 HG ++R IAP +TL A AWRL +IR+G Sbjct: 127 GICSIALPHGGILR------------IAPKNTLPP--------YDAAAENAWRLHEIRSG 166 Query: 226 VPGIVAATQEQFVPQMINFELIGGVNFKKGCYPGQEIVARSQYLGKLKRRTMLATIDSAA 285 P I AAT+E V QM+N +IGGV+FKKGCYPGQEI+AR+QY G++KR + + +S A Sbjct: 167 YPWICAATKETAVAQMLNQHIIGGVHFKKGCYPGQEIIARAQYRGQVKRGLAVLSGNS-A 225 Query: 286 AQAGQEVFAAADPGQPCGMVVNA-EALDDGRALALVEMKLAAADDTV 331 A+AG + AAD G+ G+V+++ + ++ ALA+++ A + TV Sbjct: 226 AEAGSVL--AAD-GEEAGIVLDSVQDSENFTALAVIKFSAAQKELTV 269 >NMB1024 [R] COG0354 Predicted aminomethyltransferase related to GcvT Nme Neisseria meningitidis MC58 Length = 288 Score = 152 bits (383), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 107/283 (37%), Positives = 156/283 (55%), Gaps = 27/283 (9%) Query: 52 LGLIAATGEEAASFLHGQLTNDVQHLDSNAARLAGYCSPKGRLLATLLIWRDAQTIYLQL 111 G++ +GE+ +FLHGQL+ND+ HL + A A Y +PKGR++A +++ + L + Sbjct: 9 FGVVRVSGEDRQTFLHGQLSNDINHLQTGQACYATYNTPKGRVIANMIVVNRGGDLLLIM 68 Query: 112 PRSLQPAIQKRLQMFIMRAKAKLADAGTEYAVLGLVGPAAANALAEWFPVTPAAPYDKLD 171 + L A KRL+MF++RAKA + + +YAV G A+A LA P Sbjct: 69 AQDLLEATVKRLRMFVLRAKA-VFEILEDYAV-GAELEASAEPLAAQEP----------- 115 Query: 172 NSHGSLIRMADAAGSARYQWIAPVDTLTAAWPKLAQHLKP---TASLAWRLSDIRAGVPG 228 SL A+ + P + PK A L P A AWRL +IR+G P Sbjct: 116 ----SLAFTAECGSDGICSVVLPHRGILHIAPKNA--LPPYDAAAENAWRLHEIRSGYPW 169 Query: 229 IVAATQEQFVPQMINFELIGGVNFKKGCYPGQEIVARSQYLGKLKRRTMLATIDSAAAQA 288 I AAT+E V QM+N +IGGV+FKKGCYPGQEI+AR+QY G++KR + + +S A +A Sbjct: 170 ICAATKETAVAQMLNQHIIGGVHFKKGCYPGQEIIARAQYRGQVKRGLAVLSGNS-AVEA 228 Query: 289 GQEVFAAADPGQPCGMVVNAEALDDGRALALVEMKLAAADDTV 331 G AD G+ G+V+++ D AL +K +AA T+ Sbjct: 229 G--TLLTAD-GEEAGIVLDS-VQDSENFTALTVIKFSAAQKTL 267 >STM3048 [R] COG0354 Predicted aminomethyltransferase related to GcvT Sty Salmonella typhimurium LT2 Length = 326 Score = 126 bits (316), Expect = 9e-29, Method: Compositional matrix adjust. Identities = 97/326 (29%), Positives = 153/326 (46%), Gaps = 6/326 (1%) Query: 30 LGFGPDAPAPQS-LESFMAPLTGLGLIAATGEEAASFLHGQLTNDVQHLDSNAARLAGYC 88 + F P P+ + L + L L TG ++ ++ GQ+T DV + LA +C Sbjct: 4 ISFPPRHPSSSARLPLTLIALDDWALSTITGVDSEKYIQGQVTADVSQMTEQQHLLAAHC 63 Query: 89 SPKGRLLATLLIWRDAQTIYLQLPRSLQPAIQKRLQMFIMRAKAKLADAGTEYAVLGLVG 148 KG++ +TL ++R+ RS+ A L+ + + +K +A E +LG+ G Sbjct: 64 DAKGKMWSTLRLFRERDGFAWIERRSVLEAQLTELKKYAVFSKVVIA-PDDERVLLGVAG 122 Query: 149 PAAANALAEWFPVTPAAPYDKLDNSHGSLIRMADAAGSARYQWIAPVDTLTAAWPKLAQH 208 A ALA F P + + + +L+ A R+ + V T KL Sbjct: 123 FQARAALANVFSELPNSENQVVRDGASTLLWFEHPA--ERFLLVTDVATANMLTEKLHGE 180 Query: 209 LKPTASLAWRLSDIRAGVPGIVAATQEQFVPQMINFELIGGVNFKKGCYPGQEIVARSQY 268 + S W DI AG+P I AA QF+PQ N + +GG++FKKGCY GQE+VAR+++ Sbjct: 181 AELNNSQQWLALDIEAGIPVIDAANSGQFIPQATNLQALGGISFKKGCYTGQEMVARAKF 240 Query: 269 LGKLKRRT-MLATIDSAAAQAGQEV-FAAADPGQPCGMVVNAEALDDGRALALVEMKLAA 326 G KR +LA S +AG+++ + + G ++ A LDDG+ L M Sbjct: 241 RGANKRALWLLAGKASRVPEAGEDLELQMGENWRRTGAILAATQLDDGQLLVQAVMNNDL 300 Query: 327 ADDTVHLGAADGPALHFHALPYELAD 352 ++V D LH LPY L + Sbjct: 301 EAESVFRVRDDANTLHIVPLPYSLEE 326