BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.2550.p (468 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA4024 [E] COG4303 Ethanolamine ammonia-lyase, large subunit Pae... 700 0.0 RSc3127 Non COG 668 0.0 lin1139 [E] COG4303 Ethanolamine ammonia-lyase, large subunit Li... 479 e-135 FN0079 [E] COG4303 Ethanolamine ammonia-lyase, large subunit Fnu... 475 e-134 STM2458 [E] COG4303 Ethanolamine ammonia-lyase, large subunit St... 466 e-131 >PA4024 [E] COG4303 Ethanolamine ammonia-lyase, large subunit Pae Pseudomonas aeruginosa Length = 464 Score = 700 bits (1807), Expect = 0.0, Method: Compositional matrix adjust. Identities = 336/463 (72%), Positives = 386/463 (83%), Gaps = 2/463 (0%) Query: 5 RFRHSVGSASYVFRNLKELMAKASPARSGDLLAGVAAASAEERAIAQMALAELPLKIFLE 64 RF HSVG +Y F +LK++MAKASPARSGD LAGVAA++ ER AQMALA++PLK FL+ Sbjct: 3 RFTHSVGGETYRFDSLKDVMAKASPARSGDFLAGVAASNDGERVAAQMALADIPLKHFLD 62 Query: 65 EPLIPYEDDEVTRLIIDSHDRAAFAPIAHLTVGDLRNWLLKDDTDSTVLAAVAPGITPEM 124 E LIPYEDDEVTRLIID+H R AFAP++HLTVG R+WLL D D L A+APG+TPEM Sbjct: 63 EALIPYEDDEVTRLIIDTHQRDAFAPVSHLTVGGFRDWLLGDAADEASLRALAPGLTPEM 122 Query: 125 AAAVSKIMRNQDLILVGKKCRVVTAFRNTIGLPGRLSTRLQPNHPTDDASGIAASILDGL 184 AAAVSKIMR QDL+LV +K RVVT FRNT+GL GRLSTRLQPNHPTDD +GIAASILDGL Sbjct: 123 AAAVSKIMRVQDLVLVAQKIRVVTRFRNTLGLRGRLSTRLQPNHPTDDPAGIAASILDGL 182 Query: 185 MYGNGDAVIGINPATDNVPQVVKLVGMMADVIARYEIPTQSCVLTHVTNTIAAIERGAPV 244 ++GNGDA++GINPATD++ + L+ M+ +I RYEIPTQ+CVLTHVT++I AI RG P+ Sbjct: 183 LFGNGDAMLGINPATDSMASICALLEMLDAIIQRYEIPTQACVLTHVTSSIEAINRGVPL 242 Query: 245 DLVFQSIAGTEAANRGFGIDLAILGEAREAALSLQRGTVGENVMYFETGQGSALSANAHH 304 DLVFQSIAGTEAAN FGI L IL E EA LS +RGT+G N+MYFETGQGSALSANAHH Sbjct: 243 DLVFQSIAGTEAANASFGISLKILQEGYEAGLSQKRGTLGNNLMYFETGQGSALSANAHH 302 Query: 305 GIDQQTCEARAYAVARAFKPLLVNTVVGFIGPEYLYDGKQIIRAGLEDHFCAKLLGLPMG 364 G+DQQTCE RAYAVAR FKP LVNTVVGFIGPEYLY+GKQIIRAGLEDHFC KLLG+PMG Sbjct: 303 GVDQQTCETRAYAVARHFKPFLVNTVVGFIGPEYLYNGKQIIRAGLEDHFCGKLLGVPMG 362 Query: 365 CDVCYTNHAEADQNDMDVLLTLLGVAGCTFVMGIPGSDDIMLNYQTTSFHDALYARRVLG 424 CD+CYTNHAEADQ+DMD+LLTLLGVAG F+MGIPGSDD+MLNYQTTSFHDALYAR+ LG Sbjct: 363 CDICYTNHAEADQDDMDMLLTLLGVAGINFIMGIPGSDDVMLNYQTTSFHDALYARQTLG 422 Query: 425 SRPAPEFEAWLHRMQIFNPGGDETTFRLHADMAPGFRDTLLRL 467 +PAPEFE WL RM IF + R ++ P FR L +L Sbjct: 423 LKPAPEFEDWLQRMGIFTQA--DGRIRFGDELPPAFRQALAQL 463 >RSc3127 Non COG Length = 464 Score = 668 bits (1723), Expect = 0.0, Method: Compositional matrix adjust. Identities = 334/440 (75%), Positives = 382/440 (86%) Query: 5 RFRHSVGSASYVFRNLKELMAKASPARSGDLLAGVAAASAEERAIAQMALAELPLKIFLE 64 RF H++G +Y F NL++++AKASPARSGD LAG+AAASA ER AQMALAE+PL+ FL+ Sbjct: 3 RFSHTLGHETYRFDNLRDVLAKASPARSGDALAGIAAASAAERVAAQMALAEIPLRHFLD 62 Query: 65 EPLIPYEDDEVTRLIIDSHDRAAFAPIAHLTVGDLRNWLLKDDTDSTVLAAVAPGITPEM 124 E +IPYE DEVTRLI+D+HD AAFAP++HLTVGD R+WLL D D LAA+APG+TPEM Sbjct: 63 EAVIPYEADEVTRLIVDTHDAAAFAPVSHLTVGDFRDWLLGDAADEAALAALAPGLTPEM 122 Query: 125 AAAVSKIMRNQDLILVGKKCRVVTAFRNTIGLPGRLSTRLQPNHPTDDASGIAASILDGL 184 AAAVSK+MR QDLILV +K RVVT FRNTIGL GR++TRLQPNHPTDD +GIAAS+LDGL Sbjct: 123 AAAVSKLMRVQDLILVAQKTRVVTRFRNTIGLRGRMATRLQPNHPTDDPAGIAASLLDGL 182 Query: 185 MYGNGDAVIGINPATDNVPQVVKLVGMMADVIARYEIPTQSCVLTHVTNTIAAIERGAPV 244 MYG+GDAVIG+NP +D+ + L+GM+ VI RY+IPTQ+CVLTHVT T+ AI RG PV Sbjct: 183 MYGSGDAVIGVNPVSDSTAAICDLLGMLDAVIRRYDIPTQACVLTHVTTTLEAIRRGMPV 242 Query: 245 DLVFQSIAGTEAANRGFGIDLAILGEAREAALSLQRGTVGENVMYFETGQGSALSANAHH 304 DLVFQSIAGTEAAN FG+ LA+L EAR+AAL LQRGTVG+NVMYFETGQGSALSANAHH Sbjct: 243 DLVFQSIAGTEAANASFGVSLALLHEARDAALGLQRGTVGDNVMYFETGQGSALSANAHH 302 Query: 305 GIDQQTCEARAYAVARAFKPLLVNTVVGFIGPEYLYDGKQIIRAGLEDHFCAKLLGLPMG 364 G+DQQTCEARAYAVAR F+PLLVNTVVGFIGPEYLYDGKQI+RAGLEDHFC KLLG+PMG Sbjct: 303 GVDQQTCEARAYAVARRFRPLLVNTVVGFIGPEYLYDGKQILRAGLEDHFCGKLLGVPMG 362 Query: 365 CDVCYTNHAEADQNDMDVLLTLLGVAGCTFVMGIPGSDDIMLNYQTTSFHDALYARRVLG 424 CD+CYTNHAEADQ+DMD LLTLLG AG ++MGIPGSDD+MLNYQTTSFHDALY RRVLG Sbjct: 363 CDICYTNHAEADQDDMDTLLTLLGAAGVNYIMGIPGSDDVMLNYQTTSFHDALYVRRVLG 422 Query: 425 SRPAPEFEAWLHRMQIFNPG 444 RPAPEFE WL RM I G Sbjct: 423 LRPAPEFEDWLARMGICTAG 442 >lin1139 [E] COG4303 Ethanolamine ammonia-lyase, large subunit Lin Listeria innocua Length = 454 Score = 479 bits (1234), Expect = e-135, Method: Compositional matrix adjust. Identities = 230/426 (53%), Positives = 295/426 (69%), Gaps = 3/426 (0%) Query: 14 SYVFRNLKELMAKASPARSGDLLAGVAAASAEERAIAQMALAELPLKIFLEEPLIPYEDD 73 +Y F+++ +++AKA+ +SGD LAGVAA SAEER A++ L+++ L P++PYE D Sbjct: 11 TYQFKSITDVLAKANEEKSGDRLAGVAAESAEERVAAKVVLSKMTLGDLRNNPVVPYETD 70 Query: 74 EVTRLIIDSHDRAAFAPIAHLTVGDLRNWLLKDDTDSTVLAAVAPGITPEMAAAVSKIMR 133 EVTR+I D + I + TV +LR W+L T + VA G+T E+ AAV+K+M Sbjct: 71 EVTRIIQDQVNERIHDSIKNWTVEELREWILDHKTTDADIKRVARGLTSEIIAAVTKLMS 130 Query: 134 NQDLILVGKKCRVVTAFRNTIGLPGRLSTRLQPNHPTDDASGIAASILDGLMYGNGDAVI 193 N DLI KK RV+ TIGLPG S RLQPNHPTDD GI AS+++GL YG GDAVI Sbjct: 131 NLDLIYGAKKIRVIAHANTTIGLPGTFSARLQPNHPTDDPDGILASLMEGLTYGIGDAVI 190 Query: 194 GINPATDNVPQVVKLVGMMADVIARYEIPTQSCVLTHVTNTIAAIERGAPVDLVFQSIAG 253 G+NP D+ VV+L+ + +++++PTQ+CVL HV + A+ RGAP LVFQSIAG Sbjct: 191 GLNPVDDSTDSVVRLLNKFEEFRSKWDVPTQTCVLAHVKTQMEAMRRGAPTGLVFQSIAG 250 Query: 254 TEAANRGFGIDLAILGEAREAALSLQRG-TVGENVMYFETGQGSALSANAHHGIDQQTCE 312 +E N FG D A + EAR+ L+LQ G G NVMYFETGQGS LS++AH G+DQ T E Sbjct: 251 SEKGNTAFGFDGATIEEARQ--LALQSGAATGPNVMYFETGQGSELSSDAHFGVDQVTME 308 Query: 313 ARAYAVARAFKPLLVNTVVGFIGPEYLYDGKQIIRAGLEDHFCAKLLGLPMGCDVCYTNH 372 AR Y A+ F P LVNTVVGFIGPEYLYD KQ+IRAGLEDHF KL G+ MGCDVCYTNH Sbjct: 309 ARCYGFAKKFDPFLVNTVVGFIGPEYLYDSKQVIRAGLEDHFMGKLTGISMGCDVCYTNH 368 Query: 373 AEADQNDMDVLLTLLGVAGCTFVMGIPGSDDIMLNYQTTSFHDALYARRVLGSRPAPEFE 432 +ADQND++ L LL AGC F+MGIP DD+MLNYQTT +H+ R + G +P EF+ Sbjct: 369 MKADQNDVENLSVLLTAAGCNFIMGIPHGDDVMLNYQTTGYHETATLRELFGLKPIKEFD 428 Query: 433 AWLHRM 438 W+ +M Sbjct: 429 QWMEKM 434 >FN0079 [E] COG4303 Ethanolamine ammonia-lyase, large subunit Fnu Fusobacterium nucleatum Length = 455 Score = 475 bits (1223), Expect = e-134, Method: Compositional matrix adjust. Identities = 233/435 (53%), Positives = 298/435 (68%), Gaps = 3/435 (0%) Query: 15 YVFRNLKELMAKASPARSGDLLAGVAAASAEERAIAQMALAELPLKIFLEEPLIPYEDDE 74 Y F +LKE+MAKA+ +SGD LAG+AA+S++ER A++ L+++ LK E P +PYE+DE Sbjct: 12 YNFSSLKEVMAKANEKKSGDTLAGIAASSSKERVAAKVVLSKITLKDLKENPAVPYEEDE 71 Query: 75 VTRLIIDSHDRAAFAPIAHLTVGDLRNWLLKDDTDSTVLAAVAPGITPEMAAAVSKIMRN 134 VTR+IID + + I TV DLR WLL ++ + + + G+T EM AAV+K+M N Sbjct: 72 VTRIIIDDLNLQIYDEIKDWTVSDLREWLLSEEATPSKINWIRRGLTSEMIAAVAKLMSN 131 Query: 135 QDLILVGKKCRVVTAFRNTIGLPGRLSTRLQPNHPTDDASGIAASILDGLMYGNGDAVIG 194 DLI+ KK V TIG L+ RLQPNH TDD GI S L+GL YG GDAVIG Sbjct: 132 MDLIVAAKKIEVRAHCNTTIGGYDTLAVRLQPNHTTDDPDGIMISTLEGLSYGIGDAVIG 191 Query: 195 INPATDNVPQVVKLVGMMADVIARYEIPTQSCVLTHVTNTIAAIERGAPVDLVFQSIAGT 254 +NP D+V V+ ++ + Y+IPTQ+CVL HVT + AI+RGA VD++FQSIAG+ Sbjct: 192 LNPVDDSVDSVMAVMERFHKIKTEYQIPTQTCVLAHVTTQMEAIKRGAKVDMIFQSIAGS 251 Query: 255 EAANRGFGIDLAILGEAREAALSLQRGT-VGENVMYFETGQGSALSANAHHGIDQQTCEA 313 E N FGI A++ EAR+ L L+ GT G N+MYFETGQGS LS++AH+G DQ T EA Sbjct: 252 EKGNEAFGITGAMIEEARQ--LGLKYGTAAGPNIMYFETGQGSELSSDAHNGADQVTMEA 309 Query: 314 RAYAVARAFKPLLVNTVVGFIGPEYLYDGKQIIRAGLEDHFCAKLLGLPMGCDVCYTNHA 373 R Y A+ F+P LVNTVVGFIGPEYLYD KQ+IRAGLEDHF KL GLPMG DVCYTNH Sbjct: 310 RCYGFAKRFQPFLVNTVVGFIGPEYLYDSKQVIRAGLEDHFMGKLHGLPMGVDVCYTNHM 369 Query: 374 EADQNDMDVLLTLLGVAGCTFVMGIPGSDDIMLNYQTTSFHDALYARRVLGSRPAPEFEA 433 +A+Q+D+++L TLL AGC + MG+P DDIMLNYQTT FHD R + G +P EF+ Sbjct: 370 KAEQSDVEILATLLTAAGCNYFMGVPAGDDIMLNYQTTGFHDNQSLRELFGKQPIKEFKE 429 Query: 434 WLHRMQIFNPGGDET 448 WL + G T Sbjct: 430 WLVKYGFMTEDGKLT 444 >STM2458 [E] COG4303 Ethanolamine ammonia-lyase, large subunit Sty Salmonella typhimurium LT2 Length = 453 Score = 466 bits (1199), Expect = e-131, Method: Compositional matrix adjust. Identities = 230/430 (53%), Positives = 294/430 (68%), Gaps = 1/430 (0%) Query: 15 YVFRNLKELMAKASPARSGDLLAGVAAASAEERAIAQMALAELPLKIFLEEPLIPYEDDE 74 Y F+++KE++AKA+ RSGD+LAGVAAAS++ER A+ L+E+ + P+I YE+D Sbjct: 12 YQFKDVKEVLAKANELRSGDVLAGVAAASSQERVAAKQVLSEMTVADIRNNPVIAYEEDC 71 Query: 75 VTRLIIDSHDRAAFAPIAHLTVGDLRNWLLKDDTDSTVLAAVAPGITPEMAAAVSKIMRN 134 VTRLI D + A+ I + ++ +LR ++L D+T +A G+T E+ AAV+KI N Sbjct: 72 VTRLIQDDVNETAYNRIKNWSISELREYVLSDETSVDDIAFTRKGLTSEVVAAVAKICSN 131 Query: 135 QDLILVGKKCRVVTAFRNTIGLPGRLSTRLQPNHPTDDASGIAASILDGLMYGNGDAVIG 194 DLI GKK V+ TIG+PG S RLQPN DD IAA I +GL +G GDAVIG Sbjct: 132 ADLIYGGKKMPVIKKANTTIGIPGTFSCRLQPNDTRDDVQSIAAQIYEGLSFGAGDAVIG 191 Query: 195 INPATDNVPQVVKLVGMMADVIARYEIPTQSCVLTHVTNTIAAIERGAPVDLVFQSIAGT 254 +NP TD+V + +++ + VI ++ IPTQ CVL HVT I AI RGAP L+FQSI G+ Sbjct: 192 VNPVTDDVENLTRVLDTVYGVIDKFNIPTQGCVLAHVTTQIEAIRRGAPGGLIFQSICGS 251 Query: 255 EAANRGFGIDLAILGEAREAALSLQRGTVGENVMYFETGQGSALSANAHHGIDQQTCEAR 314 E + FG++LA+L EAR R GEN +YFETGQGSALSA A+ G DQ T EAR Sbjct: 252 EKGLKEFGVELAMLDEARAVGAEFNR-IAGENCLYFETGQGSALSAGANFGADQVTMEAR 310 Query: 315 AYAVARAFKPLLVNTVVGFIGPEYLYDGKQIIRAGLEDHFCAKLLGLPMGCDVCYTNHAE 374 Y +AR + P LVNTVVGFIGPEYLY+ +QIIRAGLEDHF KL G+ MGCD CYTNHA+ Sbjct: 311 NYGLARHYDPFLVNTVVGFIGPEYLYNDRQIIRAGLEDHFMGKLSGISMGCDCCYTNHAD 370 Query: 375 ADQNDMDVLLTLLGVAGCTFVMGIPGSDDIMLNYQTTSFHDALYARRVLGSRPAPEFEAW 434 ADQN + L+ LL AGC ++MG+P DDIMLNYQTT+FHD R++L RP+PEFE W Sbjct: 371 ADQNLNENLMILLATAGCNYIMGMPLGDDIMLNYQTTAFHDTATVRQLLNLRPSPEFERW 430 Query: 435 LHRMQIFNPG 444 L M I G Sbjct: 431 LETMGIMANG 440