BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.2546.p (428 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc3059 [GEPR] COG0477 Permeases of the major facilitator superf... 622 e-178 RSc3060 [GEPR] COG0477 Permeases of the major facilitator superf... 602 e-172 STM0689 [GEPR] COG0477 Permeases of the major facilitator superf... 578 e-165 PA5476 [GEPR] COG0477 Permeases of the major facilitator superfa... 558 e-159 PA4343 [GEPR] COG0477 Permeases of the major facilitator superfa... 276 5e-74 >RSc3059 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 431 Score = 622 bits (1603), Expect = e-178, Method: Compositional matrix adjust. Identities = 297/427 (69%), Positives = 357/427 (83%), Gaps = 1/427 (0%) Query: 1 MTTSTSSQSKFSTVLRVTSGNFMEMFDFFLFGFYATHISKAFFPSDNDFASLMLTFMTFG 60 M T ++SK ++ RV SGNF+EM+DF ++G+YA I+ FFP+DN+F SLML+ +TFG Sbjct: 1 MHTHNPNESKARSIFRVVSGNFLEMYDFMVYGYYAKAIADTFFPADNEFLSLMLSLVTFG 60 Query: 61 AGFLMRPLGAIILGAYVDRVGRRQGLIVTLALMALGTMLIAFVPSYASIGALAPMLVLIG 120 GFLMRPLGA+ILGAY+DR GRR GLI+TL LMA GT+LIA VP YA+IG AP+LVLIG Sbjct: 61 VGFLMRPLGALILGAYIDRHGRRAGLILTLGLMACGTLLIALVPGYATIGLAAPLLVLIG 120 Query: 121 RLLQGFSAGVELGGVSVYLAEMATPGNKGFYVSWQSASQQVAIIVAAAIGYALSTTLTPA 180 RLLQGFSAGVELGGVSVYLAE++TPG KGF+VSWQSASQQVA++ AA +G LS L+P Sbjct: 121 RLLQGFSAGVELGGVSVYLAEISTPGRKGFFVSWQSASQQVAVMFAALLGVLLSFQLSPK 180 Query: 181 QVGDWGWRIPFFIGCLIVPVLFVIRRSLQETEEFMRRKHRPSTGQIFRSMIENWKLVIAG 240 ++G+WGWR+PF +GCLIVP LF+IRRSLQETEEF +RKHRP+ G+IFRSM ENW+LV AG Sbjct: 181 EMGEWGWRVPFLVGCLIVPFLFLIRRSLQETEEFKQRKHRPALGEIFRSMGENWRLVGAG 240 Query: 241 MMLVSMTTVSFYLITVYTPTFGKNVLKLSTEASLIVTLCVGLSNFIWLPIMGALSDRIGR 300 +LV MTTVSFYLIT YTPTFGK+VL LS SLIVTLCVG SNF WLP+MG++SDRIGR Sbjct: 241 TLLVVMTTVSFYLITAYTPTFGKSVLHLSNLDSLIVTLCVGASNFFWLPVMGSVSDRIGR 300 Query: 301 RPILVVFTVLTILTAYPAVNWLVHDATFAKMLMVELWLSFLYASYNGAMVVALTEVMPAD 360 RP+L+ FT LT+LTAYPA+ WL+ + +F ++L VELWLSFLY SYNGAMVV LTE+MP Sbjct: 301 RPLLITFTALTLLTAYPAMQWLIAEPSFGRLLAVELWLSFLYGSYNGAMVVTLTEIMPPA 360 Query: 361 VRTAGFSLAYSLATAVFGGFTPAIATGLIQATGDKAAPGIWMSTAAVCGLIATLILYRNK 420 VRT GFSLAYSLATA+FGGFTPAIAT LI ATG+KA PG+W+S AA+CGL+ATLI+ + Sbjct: 361 VRTTGFSLAYSLATAIFGGFTPAIATWLIHATGNKAMPGLWLSFAAICGLVATLIVVK-P 419 Query: 421 AARQAVT 427 A R T Sbjct: 420 AGRHVHT 426 >RSc3060 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 433 Score = 602 bits (1551), Expect = e-172, Method: Compositional matrix adjust. Identities = 287/420 (68%), Positives = 344/420 (81%) Query: 1 MTTSTSSQSKFSTVLRVTSGNFMEMFDFFLFGFYATHISKAFFPSDNDFASLMLTFMTFG 60 M T ++SK + RV SGNF+EMFDF ++G+YAT I+ FFP+ N F SLML+ MTFG Sbjct: 1 MHTHNPNESKARAIFRVVSGNFLEMFDFMVYGYYATAIAATFFPAGNAFLSLMLSLMTFG 60 Query: 61 AGFLMRPLGAIILGAYVDRVGRRQGLIVTLALMALGTMLIAFVPSYASIGALAPMLVLIG 120 AGFLMRPLGAI+LGAY+DR GRR GLI+TL LMA GTMLIA VP Y +IG AP+LVLIG Sbjct: 61 AGFLMRPLGAIVLGAYIDRHGRRAGLILTLVLMACGTMLIALVPGYGTIGLAAPLLVLIG 120 Query: 121 RLLQGFSAGVELGGVSVYLAEMATPGNKGFYVSWQSASQQVAIIVAAAIGYALSTTLTPA 180 RLLQGFSAG E GGVSVYL+E+ATPG KGFYVSWQS SQQVA++ AA +G LS L+P Sbjct: 121 RLLQGFSAGGEPGGVSVYLSEIATPGRKGFYVSWQSGSQQVAVMFAALLGVLLSFKLSPK 180 Query: 181 QVGDWGWRIPFFIGCLIVPVLFVIRRSLQETEEFMRRKHRPSTGQIFRSMIENWKLVIAG 240 ++G+WGWR+PF IGCLIVP LF IRRSL+ETEEF +RKHRP+ G++ RSM ENW+L AG Sbjct: 181 EMGEWGWRVPFLIGCLIVPFLFFIRRSLRETEEFEQRKHRPTMGELLRSMGENWRLAGAG 240 Query: 241 MMLVSMTTVSFYLITVYTPTFGKNVLKLSTEASLIVTLCVGLSNFIWLPIMGALSDRIGR 300 +L MTTVSFYLIT YTPTFG+NVL +S SLIVTLCVG SN IWLP+MG+LSDRIGR Sbjct: 241 TLLAVMTTVSFYLITAYTPTFGRNVLHMSDFDSLIVTLCVGASNLIWLPVMGSLSDRIGR 300 Query: 301 RPILVVFTVLTILTAYPAVNWLVHDATFAKMLMVELWLSFLYASYNGAMVVALTEVMPAD 360 R L+VF+ LT+LTAYPA+ WL+ + +F ++L VELWLSFLY YNGAM+V LTE+MP Sbjct: 301 RTPLIVFSALTLLTAYPAMTWLIAEPSFGRLLAVELWLSFLYGGYNGAMIVTLTEIMPPQ 360 Query: 361 VRTAGFSLAYSLATAVFGGFTPAIATGLIQATGDKAAPGIWMSTAAVCGLIATLILYRNK 420 +RT GFSLAYSLATA+FGGFTPAIATGLI ATG+KA PG+W+S AA+CGL+ATL + + + Sbjct: 361 LRTTGFSLAYSLATAIFGGFTPAIATGLIHATGNKAMPGLWLSFAAICGLVATLTVVKPQ 420 >STM0689 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 434 Score = 578 bits (1491), Expect = e-165, Method: Compositional matrix adjust. Identities = 271/416 (65%), Positives = 342/416 (82%) Query: 2 TTSTSSQSKFSTVLRVTSGNFMEMFDFFLFGFYATHISKAFFPSDNDFASLMLTFMTFGA 61 T +TS F +LRVTSGNF+E FDFFLFGFYAT+I++ FFP++++FASLMLTF FG+ Sbjct: 5 TPATSRAGTFGAILRVTSGNFLEQFDFFLFGFYATYIARTFFPAESEFASLMLTFAVFGS 64 Query: 62 GFLMRPLGAIILGAYVDRVGRRQGLIVTLALMALGTMLIAFVPSYASIGALAPMLVLIGR 121 GFLMRP+GAI+LGAY+DR+GRR+GL+VTLA+M GT+LIA VP Y +IG AP LVL+GR Sbjct: 65 GFLMRPVGAIVLGAYIDRIGRRKGLMVTLAIMGCGTLLIALVPGYQTIGLAAPALVLLGR 124 Query: 122 LLQGFSAGVELGGVSVYLAEMATPGNKGFYVSWQSASQQVAIIVAAAIGYALSTTLTPAQ 181 LLQGFSAGVELGGVSVYL+E+ATPGNKGFY SWQSASQQVAI+VAA IGY+L+ TL Sbjct: 125 LLQGFSAGVELGGVSVYLSEIATPGNKGFYTSWQSASQQVAIVVAALIGYSLNITLGHDA 184 Query: 182 VGDWGWRIPFFIGCLIVPVLFVIRRSLQETEEFMRRKHRPSTGQIFRSMIENWKLVIAGM 241 + +WGWRIPFFIGC+I+P++FV+RRSLQETE F++RKHRP T +IF ++ +NW+++ AG Sbjct: 185 ISEWGWRIPFFIGCMIIPLIFVLRRSLQETEAFLQRKHRPDTREIFATIAKNWRIITAGT 244 Query: 242 MLVSMTTVSFYLITVYTPTFGKNVLKLSTEASLIVTLCVGLSNFIWLPIMGALSDRIGRR 301 +LV+MTT +FY ITVYTPT+G+ VL LS SLIVT+ VG+SNFIWLPI GA+SDRIGRR Sbjct: 245 LLVAMTTTTFYFITVYTPTYGRTVLNLSARDSLIVTMLVGVSNFIWLPIGGAISDRIGRR 304 Query: 302 PILVVFTVLTILTAYPAVNWLVHDATFAKMLMVELWLSFLYASYNGAMVVALTEVMPADV 361 +L+ T+L ++T +P + WL F +M +V LW SF + YNGAMV ALTEVMP V Sbjct: 305 AVLMGITLLALITTWPVMQWLTAAPDFTRMTLVLLWFSFFFGMYNGAMVAALTEVMPVYV 364 Query: 362 RTAGFSLAYSLATAVFGGFTPAIATGLIQATGDKAAPGIWMSTAAVCGLIATLILY 417 RT GFSLA+SLATA+FGG TPAI+T L++ TGDK++PG W+ AA+CGL AT +L+ Sbjct: 365 RTVGFSLAFSLATAIFGGLTPAISTALVKLTGDKSSPGWWLMCAALCGLAATAMLF 420 >PA5476 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 429 Score = 558 bits (1438), Expect = e-159, Method: Compositional matrix adjust. Identities = 288/420 (68%), Positives = 349/420 (83%) Query: 6 SSQSKFSTVLRVTSGNFMEMFDFFLFGFYATHISKAFFPSDNDFASLMLTFMTFGAGFLM 65 S++SK + RV SGNF+EM+DF ++GFYAT I+K FFP DN FASLML+ TFGAGFLM Sbjct: 3 SNKSKGVAIFRVVSGNFLEMYDFMVYGFYATAIAKTFFPGDNPFASLMLSLATFGAGFLM 62 Query: 66 RPLGAIILGAYVDRVGRRQGLIVTLALMALGTMLIAFVPSYASIGALAPMLVLIGRLLQG 125 RPLGA+ LGAY+DR GRRQGLI+TL LMA+GT+LIAFVP YA++G AP+LVL GRLLQG Sbjct: 63 RPLGAVFLGAYIDRHGRRQGLIITLGLMAMGTLLIAFVPGYATLGVAAPLLVLFGRLLQG 122 Query: 126 FSAGVELGGVSVYLAEMATPGNKGFYVSWQSASQQVAIIVAAAIGYALSTTLTPAQVGDW 185 FSAGVELGGVSVYL+E+ATPG KGF+VSWQSASQQVA++ A +G L+ L+P +G+W Sbjct: 123 FSAGVELGGVSVYLSEIATPGRKGFFVSWQSASQQVAVVFAGLLGVLLNQWLSPQDMGEW 182 Query: 186 GWRIPFFIGCLIVPVLFVIRRSLQETEEFMRRKHRPSTGQIFRSMIENWKLVIAGMMLVS 245 GWR+PFFIGCLIVP LFVIRRSL+ET EF R HRPS Q+ RS+ +N+ +V+AG +V Sbjct: 183 GWRVPFFIGCLIVPALFVIRRSLEETPEFEARTHRPSLSQVLRSIGQNFGVVLAGTAMVV 242 Query: 246 MTTVSFYLITVYTPTFGKNVLKLSTEASLIVTLCVGLSNFIWLPIMGALSDRIGRRPILV 305 MTTVSFYLIT YTPTFGKN L+LS SL+VT+C+GLSNFIWLP+MGA SDRIGR+P+L+ Sbjct: 243 MTTVSFYLITAYTPTFGKNELQLSDLDSLLVTMCIGLSNFIWLPVMGAFSDRIGRKPLLL 302 Query: 306 VFTVLTILTAYPAVNWLVHDATFAKMLMVELWLSFLYASYNGAMVVALTEVMPADVRTAG 365 + L +LTAYPA++WLV + +FA +L VELWLSFLY+SYNGAMVVALTEVMPADVRT G Sbjct: 303 GASALALLTAYPALSWLVREPSFAGLLGVELWLSFLYSSYNGAMVVALTEVMPADVRTTG 362 Query: 366 FSLAYSLATAVFGGFTPAIATGLIQATGDKAAPGIWMSTAAVCGLIATLILYRNKAARQA 425 FSLAYSLATA FGGFTPA+ T LI ++AAPGIW+S AA+ GL+ATL+L+R + A Sbjct: 363 FSLAYSLATATFGGFTPAVCTWLIHTLDNRAAPGIWLSGAALLGLLATLVLFRRRGKEIA 422 >PA4343 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 439 Score = 276 bits (707), Expect = 5e-74, Method: Compositional matrix adjust. Identities = 157/418 (37%), Positives = 235/418 (56%), Gaps = 3/418 (0%) Query: 1 MTTSTSSQSKFSTVLRVTSGNFMEMFDFFLFGFYATHISKAFFPSDNDFASLMLTFMTFG 60 M S S+ V GN +E +DF ++GF ++ I++ FFPS +++ SL++ TFG Sbjct: 1 MHACPSGTSRTRQVAAAVIGNALEWYDFIVYGFLSSLIARLFFPSGDEYTSLLMALATFG 60 Query: 61 AGFLMRPLGAIILGAYVDRVGRRQGLIVTLALMALGTMLIAFVPSYASIGALAPMLVLIG 120 GF MRP+G ++LG Y DR GR+ + + + LM L +IAF P+YA+IG AP+L++I Sbjct: 61 VGFFMRPVGGVLLGLYADRRGRKAAMQLIILLMTLSIAMIAFAPTYAAIGVGAPLLIVIA 120 Query: 121 RLLQGFSAGVELGGVSVYLAEMATPGNKGFYVSWQSASQQVAIIVAAAIGYALSTTLTPA 180 R+LQGF+ G E + +L E A P +G Y SWQ Q +A+ A +G ++ L Sbjct: 121 RMLQGFATGGEYASATAFLVESAPPHRRGLYGSWQLFGQCLAVFAGAGMGALVTHCLDAE 180 Query: 181 QVGDWGWRIPFFIGCLIVPVLFVIRRSLQETEEFMRRKHRPSTGQIFRSMIENWKL-VIA 239 + WGWR+PF G LI PV IRR + ETE F+ P Q ++ ++ V+ Sbjct: 181 ALESWGWRVPFLFGLLIGPVGLWIRRYMGETEAFLEAIREPGERQGLLGVLREYRRSVLV 240 Query: 240 GMMLVSMTTVSFYLITVYTPTFGKNVLKLSTEASLIVTL-CVGLSNFIWLPIMGALSDRI 298 M L + TVSFY++ V PTF L L + +V + V L + +P+ G LSDR+ Sbjct: 241 SMGLTVVGTVSFYVVLVNMPTFAHKQLGLPLDEVFMVQMAAVALMTLV-IPLAGGLSDRV 299 Query: 299 GRRPILVVFTVLTILTAYPAVNWLVHDATFAKMLMVELWLSFLYASYNGAMVVALTEVMP 358 GRRP+L+V T+ +L YP W+ + ++L+++L L + G A+ E P Sbjct: 300 GRRPVLLVATLAFMLMVYPLFAWVAAAPSLGRLLLMQLLLCTAIGGFFGPAPTAVAEQFP 359 Query: 359 ADVRTAGFSLAYSLATAVFGGFTPAIATGLIQATGDKAAPGIWMSTAAVCGLIATLIL 416 VR+ G ++AY+LA +FGGF P I T L + G AP ++ AA GL+ATL L Sbjct: 360 VRVRSTGLAVAYNLAVMLFGGFAPFIVTWLTEVGGSPVAPAFYVLGAAFLGLLATLYL 417