BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.2499.p (245 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA3174 [K] COG1414 Transcriptional regulator Pae Pseudomonas aer... 198 1e-50 VCA0029 [K] COG1414 Transcriptional regulator Vch Vibrio cholerae 153 3e-37 TM0065 [K] COG1414 Transcriptional regulator Tma Thermotoga mari... 75 2e-13 BH2137 [K] COG1414 Transcriptional regulator Bha Bacillus halodu... 75 2e-13 SMb20682 [K] COG1414 Transcriptional regulator Sme Sinorhizobium... 75 2e-13 >PA3174 [K] COG1414 Transcriptional regulator Pae Pseudomonas aeruginosa Length = 242 Score = 198 bits (503), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 101/237 (42%), Positives = 157/237 (66%), Gaps = 3/237 (1%) Query: 10 VDRVLHVLAGVARAGKPVSAKQIAAMVQQPVSTVYRHLASLKKWGLLQEHMNSGTFEPGP 69 DR+L +L + +A + +SAK+++ + QP+S+ YRHL +L +WGL +E G + PGP Sbjct: 7 TDRLLQILIALGQAPEALSAKELSLTLGQPLSSTYRHLKTLLRWGLAEEQAGQGRYLPGP 66 Query: 70 TGVQLAWGFDQNSNLIGQSREEIISLVQRSGESVGLLVPINGQMVCIAMEESDQPLRCSF 129 +QLA FD+ ++LIG ++ E+ L S ESV L+V N Q +C+ + +S QPLRC + Sbjct: 67 ACLQLAKKFDREASLIGLAKPELKRLADLSQESVALMVASNQQAICLELFDSPQPLRCCY 126 Query: 130 VKGRAHPLLKGASAKSLLAFMPRKLQQKL-VADQLGDKPEEVAALEAQLDEIRRRGYSIS 188 KG A PLL GASAK+LLA + + +++L +A +L E + LE +L IR +GY++S Sbjct: 127 QKGLAQPLLHGASAKALLAHLEDERREELYLAQELS--AERIDKLEQELRLIREQGYAVS 184 Query: 189 ESEVDLGVWGVSVPIMTSNGRLEGTITLMAPALRVGNREQELVRMTVESAQRICNRF 245 + E+D GVWG+SVP++ S RL G ++LMAPALR +R + L + T+++A R+ R Sbjct: 185 QGEIDEGVWGISVPLLDSRQRLHGALSLMAPALRAQSRSECLRQWTLDAAARLSARL 241 >VCA0029 [K] COG1414 Transcriptional regulator Vch Vibrio cholerae Length = 244 Score = 153 bits (387), Expect = 3e-37, Method: Compositional matrix adjust. Identities = 81/229 (35%), Positives = 145/229 (63%), Gaps = 3/229 (1%) Query: 11 DRVLHVLAGVARAGKPVSAKQIAAMVQQPVSTVYRHLASLKKWGLLQEHMNSGTFEPGPT 70 ++ L +L VA +PVSAK ++ +Q P+S++YRHL LK+W L++E + T GP Sbjct: 13 EKSLQLLMQVAVNPEPVSAKGLSEQLQVPLSSLYRHLKLLKEWNLIEESPHDKTLIIGPA 72 Query: 71 GVQLAWGFDQNSNLIGQSREEIISLVQRSGESVGLLVPINGQMVCIAMEESDQPLRCSFV 130 + L ++ + + + + L +++GE +VP+ + +C++ ES Q LRCSFV Sbjct: 73 ALLLMRSYETSQHNLDAVEAVLSRLQKQTGEMAAYMVPVGYRALCVSQRESMQALRCSFV 132 Query: 131 KGRAHPLLKGASAKSLLAFMPRKLQQKLVADQLGDKPEEVAALEAQLDEIRRRGYSISES 190 +G++ PLL+GAS+K +LA+MP +K++ G+ P + +++ ++IRR GY++S S Sbjct: 133 QGQSQPLLRGASSKVMLAYMPAARCEKIL-RYFGEDP-TLDKWQSEFEKIRRHGYAVSTS 190 Query: 191 EVDLGVWGVSVPIMTSNGRLEGTITLMAPALRVGNREQELVRMTVESAQ 239 E+D GV G+S P+M + +L G I++MAPA RV + +Q ++ +++A+ Sbjct: 191 EIDPGVSGISAPVMKGS-KLIGAISVMAPAHRVESNKQRIILHVLQAAR 238 >TM0065 [K] COG1414 Transcriptional regulator Tma Thermotoga maritima Length = 246 Score = 74.7 bits (182), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 53/202 (26%), Positives = 100/202 (49%), Gaps = 6/202 (2%) Query: 12 RVLHVLAGVARAGKPVSAKQIAAMVQQPVSTVYRHLASLKKWGLLQEHMNSGTFEPGPTG 71 + +L + + VS +IA VS Y+++ L++ G + + + PG Sbjct: 6 KAFEILDFIVKNPGDVSVSEIAEKFNMSVSNAYKYMVVLEEKGFVLRKKDK-RYVPGYKL 64 Query: 72 VQLAWGFDQNSNLIGQSREEIISLVQRSGESVGLLVPINGQMVCIAMEESDQPLRCSFVK 131 ++ + N+ + + ++ +++R+GE+V L++ + V I E +Q + Sbjct: 65 IEYGSFVLRRFNIRDIAHDHLVDIMKRTGETVHLILKDGFEGVYIDKVEGEQSIPMVSRL 124 Query: 132 GRAHPLLKGASAKSLLAFMPRK-LQQKLVADQLGDK-PEEVA---ALEAQLDEIRRRGYS 186 G L AS KS+LAF+P K L++ L +L K P + L+ +L++IR+RGY+ Sbjct: 125 GMKVDLYSTASGKSILAFVPEKELKEYLKIVELKPKTPNTITNPRVLKRELEKIRKRGYA 184 Query: 187 ISESEVDLGVWGVSVPIMTSNG 208 + E ++G+ V VPI NG Sbjct: 185 VDNEENEIGIMCVGVPIFDHNG 206 >BH2137 [K] COG1414 Transcriptional regulator Bha Bacillus halodurans Length = 251 Score = 74.7 bits (182), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 56/243 (23%), Positives = 116/243 (47%), Gaps = 8/243 (3%) Query: 10 VDRVLHVLAGVARAGKPVSAKQIAAMVQQPVSTVYRHLASLKKWGLLQEHMNSGTFEPGP 69 VDR L +++ V+ + + +AA + S+ Y+ LA+L + G +++ + + G Sbjct: 5 VDRALTIISLVSEHKQGLGVTDVAAKLSLTKSSAYKLLATLVEHGFIEQDEETKKYRLGY 64 Query: 70 TGVQLAWGFDQNSNLIGQSREEIISLVQRSGESVGLLVPINGQMVCIAMEESDQPLRCSF 129 ++L+ ++ ++ Q+R + L + E V L++ G+MV I E + LR Sbjct: 65 RYLELSATLLESIDIRRQARPFLEQLEATTNEVVHLVLYDQGEMVYIDKLEGTKTLRTHS 124 Query: 130 VKGRAHPLLKGASAKSLLAFMPRKLQQKLVADQLGDKPE------EVAALEAQLDEIRRR 183 GR P+ + K ++A++P K+Q L+ ++ G P + +L++IR Sbjct: 125 KIGRRAPIHCTSVGKVIMAYLPEKVQISLI-ERYGLPPHTERTITDKETFMKELEKIRLE 183 Query: 184 GYSISESEVDLGVWGVSVPIMTSNGRLEGTITLMAPALRVGN-REQELVRMTVESAQRIC 242 GY E + G+ ++ PI G + +++ P++R+ R EL + + ++I Sbjct: 184 GYGYEMEENEPGITCIAAPIFDYQGAITAAVSISGPSIRLSKERLHELRPLIIAIGKKIS 243 Query: 243 NRF 245 R Sbjct: 244 QRL 246 >SMb20682 [K] COG1414 Transcriptional regulator Sme Sinorhizobium meliloti Length = 273 Score = 74.7 bits (182), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 58/228 (25%), Positives = 107/228 (46%), Gaps = 6/228 (2%) Query: 3 SPQTSTIVDRVLHVLAGVARAGKPVSAKQIAAMVQQPVSTVYRHLASLKKWGLLQEHMNS 62 +P + ++DR L +LA +A G + ++ STV+R L SL + ++ + Sbjct: 18 APASVQVLDRSLSLLAIIAE-GDGSTLTALSERSGMAPSTVHRLLTSLAQHEMVANDAEA 76 Query: 63 GTFEPGPTGVQLAWGFDQNSNLIGQSREEIISLVQRSGESVGLLVPINGQMVCIAMEESD 122 GT+ G ++ F + L SR + L+ SGE+ + + +G +V I+ ES Sbjct: 77 GTWTVGVKAFEIGNAFLRFRKLGTISRPFLKRLMDESGETANIGIEEDGDVVFISQVESH 136 Query: 123 QPLRCSFVKGRAHPLLKGASAKSLLAF-----MPRKLQQKLVADQLGDKPEEVAALEAQL 177 P+R F GR P+ K++L+ + + L + +A G + L + Sbjct: 137 APMRAFFRPGRRGPIHASGIGKAILSTWSDTEIAKTLSGRTLACFTGRTLATLPDLIRNV 196 Query: 178 DEIRRRGYSISESEVDLGVWGVSVPIMTSNGRLEGTITLMAPALRVGN 225 EIR RG+S+ + E LG+ ++ P+ G G I++ P +R+ + Sbjct: 197 QEIRFRGWSVDDEEHTLGMRCIAAPLFNEYGEAIGGISISGPTVRIDD 244