BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.2466.p (555 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1542 [R] COG0446 Uncharacterized NAD(FAD)-dependent dehydroge... 453 e-127 PA2345 [R] COG0446 Uncharacterized NAD(FAD)-dependent dehydrogen... 451 e-126 slr0876 [R] COG0446 Uncharacterized NAD(FAD)-dependent dehydroge... 404 e-112 SA0084 [R] COG0446 Uncharacterized NAD(FAD)-dependent dehydrogen... 367 e-101 PM1477 [R] COG0446 Uncharacterized NAD(FAD)-dependent dehydrogen... 284 3e-76 >RSc1542 [R] COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases Rso Ralstonia solanacearum Length = 421 Score = 453 bits (1166), Expect = e-127, Method: Compositional matrix adjust. Identities = 223/387 (57%), Positives = 271/387 (70%), Gaps = 3/387 (0%) Query: 167 SLLARRPGLDIAIIDPADVHYYQPGWTLVGGGVFQPAQTARVMGSLIPRGVRWIKSAVAG 226 SL RRP LDIAII+P+D HYYQP WTLVGGG F +T R +LIP GVR I+++ Sbjct: 34 SLRRRRPQLDIAIIEPSDAHYYQPAWTLVGGGAFDAGRTVRQTDALIPAGVRRIRASATH 93 Query: 227 FEPDRHAVLLEGCRVVKYQQLVVCPGLKLNWDGIEGLTDTLGRNGVSSNYRYDLAPYTWE 286 + + H V L+ R V+Y QL+V PGL+L W+ I+GL LG++GV+SNYR+DLAPYTW Sbjct: 94 IDTETHRVSLDDGRSVRYSQLIVSPGLRLAWERIDGLEAALGQHGVTSNYRFDLAPYTWS 153 Query: 287 LVQRFKGGNALFTQPPMPIKCAGAPQKAMYLSCDAWRRAGVLGQARVQFHAAGAVLFGVP 346 LV+ + G ALFTQP MPIKCAGAPQKAMYL+CD WRR GVL + V+F+ G LFGV Sbjct: 154 LVRSLRSGRALFTQPAMPIKCAGAPQKAMYLACDHWRRTGVLDRIDVEFNLTGTTLFGVE 213 Query: 347 DYVPALMEYVQAYGIALNFGQTLTAIDGSRKIATFSVTSPEGQPGKIEVPFDMIHVVPPQ 406 +VPALM YV+ Y L FG TL A+DG A F + +G+ + FD++H VPPQ Sbjct: 214 AFVPALMRYVEHYRAGLAFGSTLVAVDGPAHTAWFEHKNADGETVRAAKRFDLLHAVPPQ 273 Query: 407 SAPDFIRSSPLADAAGWIEVDQSTLQHKRFGNIFGLGDAANSPNAKTAAAARKQAPVVAH 466 AP FI S L DAAGW EVD +TLQH R ++F LGDA ++PNAKTAAA RKQA VVA Sbjct: 274 VAPAFIAQSGLGDAAGWCEVDPATLQHVRHADVFSLGDACSTPNAKTAAAVRKQAVVVAE 333 Query: 467 NVLYNLGRQTTQARYDGYGSCPLTVERGKIVLAEFNYGGKLAPSFPGWMLEGTRPSRLAW 526 N+L + RQ RYDGYG CPLTVERGK+VLAEF YGGKL P+FP L T + AW Sbjct: 334 NLLAHRDRQPLPTRYDGYGGCPLTVERGKVVLAEFGYGGKLLPTFP---LAPTVARQSAW 390 Query: 527 LLKERILPPLYWEGMLKGHEWLAQPEM 553 LK +LP LYW G+LKG EWLA+P + Sbjct: 391 WLKTTVLPWLYWNGLLKGREWLARPSL 417 >PA2345 [R] COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases Pae Pseudomonas aeruginosa Length = 411 Score = 451 bits (1160), Expect = e-126, Method: Compositional matrix adjust. Identities = 230/385 (59%), Positives = 272/385 (70%), Gaps = 3/385 (0%) Query: 167 SLLARRPGLDIAIIDPADVHYYQPGWTLVGGGVFQPAQTARVMGSLIPRGVRWIKSAVAG 226 SLL R PGL I++I+PAD HYYQPGWTLVGGG + TAR M L+P GV W+++ V Sbjct: 28 SLLKRSPGLRISLIEPADTHYYQPGWTLVGGGAYAQGDTARPMAGLVPPGVEWLRTRVER 87 Query: 227 FEPDRHAVLLEGCRVVKYQQLVVCPGLKLNWDGIEGLTDTLGRNGVSSNYRYDLAPYTWE 286 +P+ +LLEG ++Y+ L+VCPGL+L W+ IEGL +TLGRNGV+SNYRYDLAPYTWE Sbjct: 88 VDPEARRLLLEGGDSLEYRNLIVCPGLRLAWERIEGLEETLGRNGVTSNYRYDLAPYTWE 147 Query: 287 LVQRFKGGNALFTQPPMPIKCAGAPQKAMYLSCDAWRRAGVLGQARVQFHAAGAVLFGVP 346 LV+ +GG ALFTQP MPIKCAGAPQKAMYLSCD W R GVL V+F AGA LFGV Sbjct: 148 LVRGLRGGKALFTQPAMPIKCAGAPQKAMYLSCDHWLREGVLQDIEVEFDLAGAALFGVA 207 Query: 347 DYVPALMEYVQAYGIALNFGQTLTAIDGSRKIATFSVTSPEGQPGKIEVPFDMIHVVPPQ 406 D+VP LMEYV+ Y L F L +DG+ + A F V +G E FD++HVVPPQ Sbjct: 208 DFVPPLMEYVRKYSAELAFNSNLVKVDGAARKAWFEVKDADGNTNLAEKDFDLLHVVPPQ 267 Query: 407 SAPDFIRSSPLADAAGWIEVDQSTLQHKRFGNIFGLGDAANSPNAKTAAAARKQAPVVAH 466 P F+ +S L DAAGW EVD +TLQH R G IF LGD + NAKTAAAARKQ VVA Sbjct: 268 LPPTFVAASGLGDAAGWCEVDPATLQHVRHGEIFALGDVCGTANAKTAAAARKQIVVVAE 327 Query: 467 NVLYNLGRQTTQARYDGYGSCPLTVERGKIVLAEFNYGGKLAPSFPGWMLEGTRPSRLAW 526 N+L + RYDGYG CPLTVERG++VLAEF Y GKL P+FP LE T SR AW Sbjct: 328 NLLGLRSGRGLPLRYDGYGGCPLTVERGRVVLAEFGYAGKLLPTFP---LEPTAASRFAW 384 Query: 527 LLKERILPPLYWEGMLKGHEWLAQP 551 LLK +LP +YW MLKG EWLA+P Sbjct: 385 LLKRHVLPWVYWNAMLKGREWLARP 409 >slr0876 [R] COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases Syn Synechocystis Length = 409 Score = 404 bits (1039), Expect = e-112, Method: Compositional matrix adjust. Identities = 198/402 (49%), Positives = 270/402 (67%), Gaps = 12/402 (2%) Query: 149 SHQVVIIGGGAAGISVASSLLARRPGLDIAIIDPADVHYYQPGWTLVGGGVFQPAQTARV 208 +HQ++++GGGAAGI+VA+ LL ++P LD+AI++P D HYYQP WTLVGGG F T + Sbjct: 5 NHQIIVVGGGAAGITVAAQLLKQKPKLDLAIVEPCDKHYYQPAWTLVGGGAFAMEDTIKP 64 Query: 209 MGSLIPRGVRWIKSAVAGFEPDRHAVLLEGCRVVKYQQLVVCPGLKLNWDGIEGLTDTLG 268 IP G +WIK++VA F+P+ + + L+ R + Y+ LVVCPG+++NW I L ++LG Sbjct: 65 EQDCIPSGAKWIKASVASFDPENNCLTLQDGRSLSYEYLVVCPGIQINWHLIPRLQESLG 124 Query: 269 RNGVSSNYRYDLAPYTWELVQRFKGGNALFTQPPMPIKCAGAPQKAMYLSCDAWRRAGVL 328 +NGV+SNY APYTWEL+Q FKGGNALFT P PIKCAGAPQK MYL+ + +R+ GV Sbjct: 125 KNGVTSNYDRRYAPYTWELLQNFKGGNALFTFPATPIKCAGAPQKIMYLADETFRKNGVR 184 Query: 329 GQARVQFHAAGAVLFGVPDYVPALMEYVQAYGIALNFGQTLTAIDGSRKIATFSVTSPEG 388 + + + A +FG+P Y +L + I + + L AI+ + K ATF+V Sbjct: 185 EKTNITYGVAVGKIFGIPGYCESLEKVAAKKNIDVRYHHNLKAINPNAKEATFTVN---- 240 Query: 389 QPGKIEV--PFDMIHVVPPQSAPDFIRSSPL-ADAAGWIEVDQSTLQHKRFGNIFGLGDA 445 GK EV P+D+IHV PP SAPDFI++SPL A+A GW++VD+ TLQH R+ N+F LGDA Sbjct: 241 --GKTEVTLPYDIIHVTPPMSAPDFIKNSPLAAEAGGWVDVDKFTLQHNRYDNVFSLGDA 298 Query: 446 ANSPNAKTAAAARKQAPVVAHNVLYNLGRQTTQARYDGYGSCPLTVERGKIVLAEFNYGG 505 ++ P ++TAAA RKQAPVVA N+L L + A Y GY CPL GK ++AEF+YGG Sbjct: 299 SSLPTSRTAAAVRKQAPVVATNLLGLLNSKKPSAEYGGYTCCPLVTGYGKTIMAEFDYGG 358 Query: 506 KLAPSFPGWMLEGTRPSRLAWLLKERILPPLYWEGMLKGHEW 547 + SFP + T+ WL+K +LP LYW MLKG + Sbjct: 359 QPKSSFP---FDPTQERWSMWLVKRYVLPWLYWNRMLKGESF 397 >SA0084 [R] COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases Sau Staphylococcus aureus N315 Length = 397 Score = 367 bits (941), Expect = e-101, Method: Compositional matrix adjust. Identities = 176/400 (44%), Positives = 241/400 (60%), Gaps = 8/400 (2%) Query: 147 DSSHQVVIIGGGAAGISVASSLLARRPGLD--IAIIDPADVHYYQPGWTLVGGGVFQPAQ 204 + +Q+VIIGGG AG++VAS LL + L IAIIDPAD HYYQP WTLVG GV Sbjct: 2 NKHYQIVIIGGGTAGVTVASRLLRKNQNLKEKIAIIDPADHHYYQPLWTLVGAGVSSLKS 61 Query: 205 TARVMGSLIPRGVRWIKSAVAGFEPDRHAVLLEGCRVVKYQQLVVCPGLKLNWDGIEGLT 264 + + M S+IP G WIK AV+ F+P+ ++V+L VV Y LVV PGL++NW I+GL Sbjct: 62 SRKDMESVIPEGANWIKQAVSSFQPENNSVILGDNTVVYYDFLVVAPGLQINWSSIKGLK 121 Query: 265 DTLGRNGVSSNYRYDLAPYTWELVQRFKGGNALFTQPPMPIKCAGAPQKAMYLSCDAWRR 324 + +G+NGV SNY D TW + FK GNA+FT P PIKC GAP K MYL+ D +R+ Sbjct: 122 ENIGKNGVCSNYSPDYVNETWNQISNFKQGNAIFTHPNTPIKCGGAPMKIMYLAEDYFRK 181 Query: 325 AGVLGQARVQFHAAGAVLFGVPDYVPALMEYVQAYGIALNFGQTLTAIDGSRKIATFSVT 384 + A V + LF V Y L V+ I +N+ L IDG +K+ATF Sbjct: 182 HKIRSNANVIYATPKDALFDVGKYNKELERIVEERNITVNYNYNLVEIDGDKKVATFEHI 241 Query: 385 SPEGQPGKIEVPFDMIHVVPPQSAPDFIRSSPLADAAGWIEVDQSTLQHKRFGNIFGLGD 444 + + +DM+HV PP D ++ S L+D+ GW++V+ +TLQHK + N+F LGD Sbjct: 242 KAYDRK---TISYDMLHVTPPMGPLDVVKESTLSDSEGWVDVNPTTLQHKSYSNVFALGD 298 Query: 445 AANSPNAKTAAAARKQAPVVAHNVLYNLGRQTTQARYDGYGSCPLTVERGKIVLAEFNYG 504 A+N P +KT AA RKQAP+VA+N+L + Q YDGY SCP+ +++LAEF+Y Sbjct: 299 ASNVPTSKTGAAIRKQAPIVANNLLQVMNNQMLTHHYDGYTSCPIVTGYNRLILAEFDYN 358 Query: 505 GKLAPSFPGWMLEGTRPSRLAWLLKERILPPLYWEGMLKG 544 + P + R ++ K+ +LP +YW GMLKG Sbjct: 359 KNTKETMP---FNQAKERRSMYIFKKDLLPKMYWYGMLKG 395 >PM1477 [R] COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases Pmu Pasteurella multocida Length = 449 Score = 284 bits (727), Expect = 3e-76, Method: Compositional matrix adjust. Identities = 165/408 (40%), Positives = 234/408 (57%), Gaps = 18/408 (4%) Query: 148 SSHQVVIIGGGAAGISVASSLLAR-RPGLDIAIIDPADVHYYQPGWTLVGGGVFQPAQTA 206 SS ++VI G GAAG+++AS L AR P I +ID HYYQPG+TLV G+ Sbjct: 47 SSAKIVIAGAGAAGLTIASQLAARLEPSAQIILIDSRIAHYYQPGFTLVAAGIKPKHYVV 106 Query: 207 RVMGSLIPRGVRWIKSAVAGFEPDRHAVLLEGCRVVKYQQLVVCPGLKLNWDGIEGL-TD 265 +P V+WIK+AV F+PD + + + Y L V GLKL++D IEG+ + Sbjct: 107 SQTEEYLPDNVKWIKAAVNEFDPDSNRLTTSTGEHITYDYLFVATGLKLDYDAIEGMDVN 166 Query: 266 TLGRNGVSSNYRY-DLAPYTWELVQRF--KGGNALFTQPPMPIKCAGAPQKAMYLSCDAW 322 +G+NG+ S Y D A TW+L+ +F KGG+A+F +P +KCAGAP K ++ D Sbjct: 167 LIGQNGLGSIYHSPDSAYKTWQLLDQFANKGGDAVFLRPATEMKCAGAPLKYTFIVRDYL 226 Query: 323 RRAGVLGQARVQFHAAGAVLFGVPDYVPALMEYVQAYGIALNFGQTLTAIDGSRKIATFS 382 R L ++R+ ++A LF VP + I +N+ ++LTAID S++IATF+ Sbjct: 227 LRRHTLDKSRLFYNAHNKTLFSVPIVDAKVKMLFAEKNIQVNYDRSLTAIDLSKRIATFN 286 Query: 383 VTSPEGQPGKIEVPFDMIHVVPPQSAPDFIRSSPLA------DAAGWIEVDQSTLQHKRF 436 SPEG +EVP+D I+VVPP APD +R S LA GW+EV++ TL+H+R+ Sbjct: 287 --SPEGV---VEVPYDFINVVPPMRAPDAVRQSALAWQEGKWANDGWVEVEKHTLRHRRY 341 Query: 437 GNIFGLGDAANSPNAKTAAAARKQAPVVAHNVLYNLGRQTTQARYDGYGSCPLTVERGKI 496 N+F +GD A P KTAA+ + Q PV ++L L + Y+GY SCPL + GK Sbjct: 342 ANVFAVGDVAGVPKGKTAASVKWQVPVAVAHLLAELEGKPCDEIYNGYTSCPLITQLGKG 401 Query: 497 VLAEFNYGGKLAPSFPGWMLEGTRPSRLAWLLKERILPPLYWEGMLKG 544 +L EF+Y L PSFPG ++ W +K L P Y GML+G Sbjct: 402 MLVEFDYNNHLTPSFPG-VIAPLEELWATWAIKTLGLKPTYL-GMLRG 447