BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.2444.p (254 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH2137 [K] COG1414 Transcriptional regulator Bha Bacillus halodu... 132 1e-30 TM0065 [K] COG1414 Transcriptional regulator Tma Thermotoga mari... 122 9e-28 BH1819 [K] COG1414 Transcriptional regulator Bha Bacillus halodu... 121 1e-27 DR1156 [K] COG1414 Transcriptional regulator Dra Deinococcus rad... 115 1e-25 Z2874 [K] COG1414 Transcriptional regulator EcZ Escherichia coli... 111 2e-24 >BH2137 [K] COG1414 Transcriptional regulator Bha Bacillus halodurans Length = 251 Score = 132 bits (331), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 81/249 (32%), Positives = 131/249 (52%), Gaps = 2/249 (0%) Query: 5 VDAVSKAIELLFLVAE-EGGNGVTELAKRSGNTKARAFRLLTTLEECGLVRRQLPMATYS 63 V +V +A+ ++ LV+E + G GVT++A + TK+ A++LL TL E G + + Y Sbjct: 2 VKSVDRALTIISLVSEHKQGLGVTDVAAKLSLTKSSAYKLLATLVEHGFIEQDEETKKYR 61 Query: 64 LGYRALILGTAAQGQLSLVNVARDILEDIGNECNESVLVRVRDGMDTVCVAWWDAPHAIR 123 LGYR L L + + AR LE + NE V + + D + V + + +R Sbjct: 62 LGYRYLELSATLLESIDIRRQARPFLEQLEATTNEVVHLVLYDQGEMVYIDKLEGTKTLR 121 Query: 124 VHSQLGDRRPLSAGASGKLLLAYAPADVQAEILSGK-LEKFTPNTIVKQTDLKKELKKIL 182 HS++G R P+ + GK+++AY P VQ ++ L T TI + KEL+KI Sbjct: 122 THSKIGRRAPIHCTSVGKVIMAYLPEKVQISLIERYGLPPHTERTITDKETFMKELEKIR 181 Query: 183 AEGFSISHSEKTADMVAVAAPVRDSQGHVVASLSMTAPSSRVPKEKLDKYVKIITQAAAR 242 EG+ E + +AAP+ D QG + A++S++ PS R+ KE+L + +I + Sbjct: 182 LEGYGYEMEENEPGITCIAAPIFDYQGAITAAVSISGPSIRLSKERLHELRPLIIAIGKK 241 Query: 243 FSRLLGYVD 251 S+ LGY D Sbjct: 242 ISQRLGYQD 250 >TM0065 [K] COG1414 Transcriptional regulator Tma Thermotoga maritima Length = 246 Score = 122 bits (305), Expect = 9e-28, Method: Compositional matrix adjust. Identities = 75/247 (30%), Positives = 136/247 (55%), Gaps = 3/247 (1%) Query: 5 VDAVSKAIELL-FLVAEEGGNGVTELAKRSGNTKARAFRLLTTLEECGLVRRQLPMATYS 63 ++ + KA E+L F+V G V+E+A++ + + A++ + LEE G V R+ Y Sbjct: 1 MNTLKKAFEILDFIVKNPGDVSVSEIAEKFNMSVSNAYKYMVVLEEKGFVLRKKD-KRYV 59 Query: 64 LGYRALILGTAAQGQLSLVNVARDILEDIGNECNESVLVRVRDGMDTVCVAWWDAPHAIR 123 GY+ + G+ + ++ ++A D L DI E+V + ++DG + V + + +I Sbjct: 60 PGYKLIEYGSFVLRRFNIRDIAHDHLVDIMKRTGETVHLILKDGFEGVYIDKVEGEQSIP 119 Query: 124 VHSQLGDRRPLSAGASGKLLLAYAPADVQAEILS-GKLEKFTPNTIVKQTDLKKELKKIL 182 + S+LG + L + ASGK +LA+ P E L +L+ TPNTI LK+EL+KI Sbjct: 120 MVSRLGMKVDLYSTASGKSILAFVPEKELKEYLKIVELKPKTPNTITNPRVLKRELEKIR 179 Query: 183 AEGFSISHSEKTADMVAVAAPVRDSQGHVVASLSMTAPSSRVPKEKLDKYVKIITQAAAR 242 G+++ + E ++ V P+ D G+ VA +S++ + + +EK+++Y ++ + A Sbjct: 180 KRGYAVDNEENEIGIMCVGVPIFDHNGYPVAGVSISGVARKFTEEKIEEYSDVLKEKAEE 239 Query: 243 FSRLLGY 249 SR LGY Sbjct: 240 ISRKLGY 246 >BH1819 [K] COG1414 Transcriptional regulator Bha Bacillus halodurans Length = 252 Score = 121 bits (304), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 79/244 (32%), Positives = 128/244 (52%), Gaps = 2/244 (0%) Query: 8 VSKAIELLFLVAEEGGNGVTELAKRSGNTKARAFRLLTTLEECGLVRRQLPMATYSLGYR 67 V K++ LL L + E+ K+SG K R++ +LEE G ++++ A Y LG Sbjct: 8 VIKSMNLLNLFRTYPTLTLQEMVKQSGMPKTSVHRMINSLEEMGFLQKRHDGA-YELGVV 66 Query: 68 ALILGTAAQGQLSLVNVARDILEDIGNECNESVLVRVRDGMDTVCVAWWDAPHAIRVHSQ 127 L LG +L L VA I+E + N+ E+V + VRDG + + + D H +R+ ++ Sbjct: 67 FLELGQLVSDRLDLRQVAFPIMEALRNQVEEAVHLTVRDGDEAIYIEKLDTLHPVRLFTK 126 Query: 128 LGDRRPLSAGASGKLLLAYAPADVQAEILSG-KLEKFTPNTIVKQTDLKKELKKILAEGF 186 +G R PL AGA +++L++ P Q L +L TI + LK+ + + G Sbjct: 127 VGRRAPLYAGACQRVILSFLPEQEQTAYLERVELIPLADGTITDKLLLKERISETQQTGV 186 Query: 187 SISHSEKTADMVAVAAPVRDSQGHVVASLSMTAPSSRVPKEKLDKYVKIITQAAARFSRL 246 +ISHSE + A+AAP+ D G +VA +S+ P RV +E+L + AA S+ Sbjct: 187 AISHSELENNTTAIAAPIYDHSGTIVAGISIAGPDIRVTEERLSTLKVTLKNAAKSISKQ 246 Query: 247 LGYV 250 LG++ Sbjct: 247 LGWL 250 >DR1156 [K] COG1414 Transcriptional regulator Dra Deinococcus radiodurans Length = 267 Score = 115 bits (287), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 72/247 (29%), Positives = 135/247 (54%), Gaps = 1/247 (0%) Query: 4 TVDAVSKAIELLFLVAEEGGNGVTELAKRSGNTKARAFRLLTTLEECGLVRRQLPMATYS 63 +V + + + +L +AE +T++AK++G + + +RLL TL + G V + +S Sbjct: 19 SVRTLERGLSVLSALAELREATLTQVAKKAGLSASTTYRLLETLRQQGYVEWEERSGLFS 78 Query: 64 LGYRALILGTAAQGQLSLVNVARDILEDIGNECNESVLVRVRDGMDTVCVAWWDAPHAIR 123 +G RA +G A + SL++ A +++ + E NE+ + V G + V V +A +R Sbjct: 79 VGLRAYQVGAAFSERNSLLSAAGAVMQALVEEVNETANLAVLRGNEAVYVHQVEASQLMR 138 Query: 124 VHSQLGDRRPLSAGASGKLLLAY-APADVQAEILSGKLEKFTPNTIVKQTDLKKELKKIL 182 + + +G PL GK+L A+ PA+V+ ++ G +TP++I L +EL + Sbjct: 139 MFTHIGAAAPLHCSGVGKVLTAWLPPAEVRRKVGDGPFPAYTPHSITTLAALTRELNTVR 198 Query: 183 AEGFSISHSEKTADMVAVAAPVRDSQGHVVASLSMTAPSSRVPKEKLDKYVKIITQAAAR 242 + +++ E+ + +A PVR + G VVASLS++AP+SR PK+ + + + A+ + Sbjct: 199 GQDYALDDEERELGVRCLATPVRAASGEVVASLSVSAPTSRFPKKNIPDMLGRVQAASEQ 258 Query: 243 FSRLLGY 249 S LG+ Sbjct: 259 ISARLGW 265 >Z2874 [K] COG1414 Transcriptional regulator EcZ Escherichia coli O157:H7 EDL933 Length = 263 Score = 111 bits (277), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 74/249 (29%), Positives = 130/249 (52%), Gaps = 1/249 (0%) Query: 4 TVDAVSKAIELLFLVAEEGGNGVTELAKRSGNTKARAFRLLTTLEECGLVRRQLPMATYS 63 +V +V K +L + EE G+TEL++R +K+ +R L T++ G V ++ YS Sbjct: 12 SVSSVLKVFGILQALGEEREIGITELSQRVMMSKSTVYRFLQTMKTLGYVAQEGESEKYS 71 Query: 64 LGYRALILGTAAQGQLSLVNVARDILEDIGNECNESVLVRVRDGMDTVCVAWWDAPHAIR 123 L + LG A + L+ A + +I E++ + D V + D+ + +R Sbjct: 72 LTLKLFELGARALQNVDLIRSADIQMREISRLTKETIHLGALDEBSIVYIHKIDSMYNLR 131 Query: 124 VHSQLGDRRPLSAGASGKLLLAYAPADVQAEILSG-KLEKFTPNTIVKQTDLKKELKKIL 182 ++S++G R PL + A GK+LLA+ D +IL G + ++ T TI L L ++ Sbjct: 132 MYSRIGRRNPLYSTAIGKVLLAWRDRDEVKQILEGVEYKRSTERTITSTEALLPVLDQVR 191 Query: 183 AEGFSISHSEKTADMVAVAAPVRDSQGHVVASLSMTAPSSRVPKEKLDKYVKIITQAAAR 242 +G+ + E+ + +A PV D G V+A LS++ P+ R +E+L +YV ++ AA + Sbjct: 192 EQGYGEDNEEQEEGLRCIAVPVFDRFGVVIAGLSISFPTLRFSEERLQEYVAMLHTAARK 251 Query: 243 FSRLLGYVD 251 S +GY D Sbjct: 252 ISAQMGYHD 260