BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.2434.p (283 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGl2891 [V] COG2367 Beta-lactamase class A Atu Agrobacterium tum... 317 3e-86 SMc02026 Non COG 313 3e-85 all4822_2 [V] COG2367 Beta-lactamase class A Nos Nostoc sp. PCC ... 66 7e-11 DR0433 [V] COG2367 Beta-lactamase class A Dra Deinococcus radiod... 64 4e-10 FN1584 [V] COG2367 Beta-lactamase class A Fnu Fusobacterium nucl... 62 1e-09 >AGl2891 [V] COG2367 Beta-lactamase class A Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 288 Score = 317 bits (811), Expect = 3e-86, Method: Compositional matrix adjust. Identities = 150/273 (54%), Positives = 194/273 (71%) Query: 7 RLNAICDEQPYVTAWYFKNLVTGEEADRDGHVAFPSGSTRKTSILMAVLRAINQGRLDLN 66 +LNAICD QP+VT + +NL+TGEE R + PSGSTRKTSI+MAVL+A ++GR+DL+ Sbjct: 14 QLNAICDVQPFVTRFMVRNLLTGEEIGRGENEETPSGSTRKTSIMMAVLKAASEGRIDLD 73 Query: 67 APILYEERLRKGVVSGTFKFLTPGFTISLRDALVQMIIVSDNVCTAMVMERISLDEVNEF 126 P+ YE+RL + V SG F+++TPG ISLRDA+ M+++SDNVCT MV+ER++L+EV+ + Sbjct: 74 QPVTYEKRLAEEVASGMFRYMTPGIVISLRDAIAGMMVLSDNVCTKMVLERLTLEEVDGY 133 Query: 127 CHSIGMRNTLHRNSVPRPDMPTDHKLDEVTTISACDQGLLYDLILKGSTDPEVAQRLGCT 186 C S+GM NT HR +P + DH L VTT SA DQ LL IL + PE +LGC+ Sbjct: 134 CKSLGMANTHHRFLIPPLALAADHPLKTVTTTSAADQVLLLQTILDAQSSPEAQAKLGCS 193 Query: 187 PQQCAFAIEVLSWQKLRTKMASLLPSDTKVAHKGGTGKRGRMDGGIVFRNDQPLFILTGY 246 PQ C +A++ L Q LR + S LP + VA K G GKRGRMD GIV+RN P FI+T Y Sbjct: 194 PQLCEWAMQTLKNQILRYGIRSRLPFEAMVASKSGRGKRGRMDAGIVYRNGAPSFIITTY 253 Query: 247 TDQVPWEMPDGLPGYVSAFNTLGRLARACWDGI 279 TD+VP MPDG PGY A T+GRLA+ACWDG Sbjct: 254 TDEVPQVMPDGTPGYTIALETIGRLAQACWDGF 286 >SMc02026 Non COG Length = 278 Score = 313 bits (802), Expect = 3e-85, Method: Compositional matrix adjust. Identities = 147/273 (53%), Positives = 188/273 (68%) Query: 7 RLNAICDEQPYVTAWYFKNLVTGEEADRDGHVAFPSGSTRKTSILMAVLRAINQGRLDLN 66 RL ICD QP+VT + +NL TGE +R PS STRKTSI+MA L+A+++GRL L+ Sbjct: 4 RLAHICDAQPFVTRFVVRNLKTGETIERGADEETPSASTRKTSIMMAALKAVHEGRLALD 63 Query: 67 APILYEERLRKGVVSGTFKFLTPGFTISLRDALVQMIIVSDNVCTAMVMERISLDEVNEF 126 PI YE R + V SG F++LTPG ISLRDA+ M+++SDNVCT MV ER++L+EV+ + Sbjct: 64 EPITYEARFAEEVASGMFRYLTPGIVISLRDAITGMMVLSDNVCTKMVFERLTLEEVDSY 123 Query: 127 CHSIGMRNTLHRNSVPRPDMPTDHKLDEVTTISACDQGLLYDLILKGSTDPEVAQRLGCT 186 C SIGM T HR +P +P DH L VTT +A DQ L IL T PEV +LG + Sbjct: 124 CKSIGMHGTHHRFLIPPLALPPDHSLTSVTTTTARDQAFLLQTILDAQTSPEVIAKLGTS 183 Query: 187 PQQCAFAIEVLSWQKLRTKMASLLPSDTKVAHKGGTGKRGRMDGGIVFRNDQPLFILTGY 246 P+ CA+A++ L Q LR + S LP T VAHKGGTGKRGRM+ GIV+R+ P +I++ Y Sbjct: 184 PELCAYALQTLKNQILRYAIPSRLPFGTVVAHKGGTGKRGRMNAGIVYRDGAPFYIISAY 243 Query: 247 TDQVPWEMPDGLPGYVSAFNTLGRLARACWDGI 279 TD+VP MPDG PGY A T+GRL+RACWDG Sbjct: 244 TDEVPQVMPDGTPGYTMALETIGRLSRACWDGF 276 >all4822_2 [V] COG2367 Beta-lactamase class A Nos Nostoc sp. PCC 7120 Length = 314 Score = 66.2 bits (160), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 58/221 (26%), Positives = 98/221 (44%), Gaps = 35/221 (15%) Query: 22 YFKNLVTGEEADRDGHVAFPSGSTRKTSILMAVLRAINQGRLDLNAPILYEERLRKGVVS 81 +F ++ TGE D +G F + ST K IL+A+ I+ GR++ N ++ L G S Sbjct: 73 FFLDMETGEYLDINGEKTFAAASTIKFPILIALFEEIDAGRINPNETLVMRRDLMTG-GS 131 Query: 82 GTFKFLTPGFTISLRDALVQMIIVSDNVCTAMVMERI-SLDEVNEFCHSIGMRNTLHRNS 140 GT ++ G L + +M+I+SDN T M+++R+ + +N+ + G++NT+ RN Sbjct: 132 GTMQYRKAGSRFKLMETASKMMIISDNTATNMIIDRLGGKNRLNQKFRTWGLQNTVIRN- 190 Query: 141 VPRPDMPTDHKLDEVTTISACDQGLLYDLILKGSTDPEVAQRLGC--------TPQQCAF 192 LL D T P+ RL + + Sbjct: 191 ------------------------LLGDFKGTNKTSPKDLVRLAALISNNKLLSATSNSR 226 Query: 193 AIEVLSWQKLRTKMASLLPSDTKVAHKGGTGKRGRMDGGIV 233 ++++S K R+ + L +AHK GT R D GI+ Sbjct: 227 VMDIMSRCKNRSLLPVGLGKGAVIAHKTGTLGRVLGDAGII 267 >DR0433 [V] COG2367 Beta-lactamase class A Dra Deinococcus radiodurans Length = 277 Score = 63.9 bits (154), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 60/226 (26%), Positives = 99/226 (43%), Gaps = 22/226 (9%) Query: 40 FPSGSTRKTSILMAVLRAINQGRLDL--NAPILYEERLRKGVVSGTFKFLTPGFTISLRD 97 FP+ ST K +L+ L +G LDL + E+R+ +G L G ++ +D Sbjct: 39 FPAASTIKVPLLLFALEQAGRGDLDLIERVTLRAEDRVPG---AGVLHELGLGLALTWQD 95 Query: 98 ALVQMIIVSDNVCTAMVMERISLDEVNEFCHSIGMRNT--LHRNSVPRPDMPTDHKLDEV 155 L MI+VSDN T +++ER+ D N + + G+ +T + +P + E Sbjct: 96 VLTLMIVVSDNTATNLLIERLGQDHFNLWLTARGLNSTRLIGPLQLPPERQNEAQRRGER 155 Query: 156 TTISACDQGLLYDLILKGSTDPEVAQRLGCTPQQCAFAIEVLSWQKLRTKMASLLPSDT- 214 +A DQ L +L+G G TPQ A+++LS Q LR + +P+ Sbjct: 156 NRTTARDQVALLLSLLRGD---------GLTPQMQHLALDILSRQHLRDLIGRGVPAGPD 206 Query: 215 -----KVAHKGGTGKRGRMDGGIVFRNDQPLFILTGYTDQVPWEMP 255 +VA K G + D G+++ + L + P E P Sbjct: 207 GEPLYRVASKSGELRGVHHDVGLLWAPRPLVVALLSQGGEDPREHP 252 >FN1584 [V] COG2367 Beta-lactamase class A Fnu Fusobacterium nucleatum Length = 264 Score = 62.0 bits (149), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 57/243 (23%), Positives = 108/243 (44%), Gaps = 23/243 (9%) Query: 35 DGHVAFPSGSTRKTSILMAVLRAINQGRLDLNAPILYEERLRKGVVSGTFKFLTPGFTIS 94 +G+ S S K IL +++ +++ + L+ I ++ G G K L G + Sbjct: 38 NGNEKVLSASMIKLLILAELMKKVSENKFSLSDTITITNFMKTGG-DGVLKELNAGHHFT 96 Query: 95 LRDALVQMIIVSDNVCTAMVMERISLDEVNEFCHSIGMRNTLHRNSVPRPDMPTDHKLDE 154 L++ MIIVSDN T ++++ + ++ +N +G+R T + + + + D Sbjct: 97 LKELATLMIIVSDNQATNILIDFLGMENINFLGKELGLRETFLERRMMDAE-ASKNGYDN 155 Query: 155 VTTISACDQGLLYDLILKGSTDPEVAQRLGCTPQQCAFAIEVLSWQKLRTKMASLLPSDT 214 T SA D LL LI Q + +++L Q+ ++ LP D Sbjct: 156 YT--SADDISLLLKLI---------YQEKLINKETSQLMLDILLRQQQGERLQRYLPPDI 204 Query: 215 KVAHKGGTGKRGRMDGGIVFRNDQPLFILTGYTDQVPWEMPDGLPGYVSAFNTLGRLARA 274 K+AHK G DGGI++ ++ ++IL T G+ + T+G++++ Sbjct: 205 KIAHKCGDLDNLENDGGIIWLGNK-IYILVVLT--------SGMSN-LQCRQTIGKISKF 254 Query: 275 CWD 277 +D Sbjct: 255 VYD 257