BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.2375.p (251 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH0419 [K] COG2188 Transcriptional regulators Bha Bacillus halod... 110 3e-24 BS_yvoA [K] COG2188 Transcriptional regulators Bsu Bacillus subt... 107 4e-23 BMEII0116 [K] COG2188 Transcriptional regulators Bme Brucella me... 105 1e-22 BMEII0383 [K] COG2188 Transcriptional regulators Bme Brucella me... 103 5e-22 PA2299 [K] COG2188 Transcriptional regulators Pae Pseudomonas ae... 101 1e-21 >BH0419 [K] COG2188 Transcriptional regulators Bha Bacillus halodurans Length = 240 Score = 110 bits (276), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 63/208 (30%), Positives = 105/208 (50%), Gaps = 2/208 (0%) Query: 12 LPRYRWLADIIRDTIDRGLFTDNQALPPERELAEHYEVSRDTVRKALRYMEERGIIYSDH 71 LP Y + + I+ I+ G+ L ERE AE+Y+VSR TVR+A+ + +G IY Sbjct: 8 LPIYYQIEEQIKQQIESGVLKPGDMLKSEREYAEYYDVSRMTVRQAINNLVNQGYIYKKK 67 Query: 72 GRGTFVSPAIVRGTTRFIDSFSQDTGNRGGVPGQRIISIENVGASMAIATLLNIESGTPL 131 G GT+V + + SF++D RG P R++ E + A+ IA LN++ TP+ Sbjct: 68 GSGTYVQEKKIEQALNGLTSFTEDMRKRGMEPSSRLLKFELIPATAKIAKELNLKENTPV 127 Query: 132 VRVRRVRLIDDAPVGVHDAHLVLPRGSRLTRSQIERSGSLYKLLTAQYGFDPAEAVENLC 191 ++R+R D P+ + L L I + SLY+ + + A+A++ + Sbjct: 128 TEIKRIRYGDGVPIAIERNLLPANLVKGLNEEIINQ--SLYQYIEEELNLRIADALQVIE 185 Query: 192 AGAADADDAQWLDVPVAAPLLICERITL 219 A A +A L++ +P+L+ ER T Sbjct: 186 ASTASKTEADLLEIQKGSPILLIERKTF 213 >BS_yvoA [K] COG2188 Transcriptional regulators Bsu Bacillus subtilis Length = 243 Score = 107 bits (266), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 60/210 (28%), Positives = 107/210 (50%), Gaps = 2/210 (0%) Query: 9 EAQLPRYRWLADIIRDTIDRGLFTDNQALPPERELAEHYEVSRDTVRKALRYMEERGIIY 68 ++ +P Y + + ++ I G + LP ERE AE + +SR TVR+AL + G++Y Sbjct: 6 QSPIPIYYQIMEQLKTQIKNGELQPDMPLPSEREYAEQFGISRMTVRQALSNLVNEGLLY 65 Query: 69 SDHGRGTFVSPAIVRGTTRFIDSFSQDTGNRGGVPGQRIISIENVGASMAIATLLNIESG 128 GRGTFVS + + + SF++D +RG PG R+I + + ++ +A +L Sbjct: 66 RLKGRGTFVSKPKMEQALQGLTSFTEDMKSRGMTPGSRLIDYQLIDSTEELAAILGCGHP 125 Query: 129 TPLVRVRRVRLIDDAPVGVHDAHLVLPRGSRLTRSQIERSGSLYKLLTAQYGFDPAEAVE 188 + + ++ RVRL +D P+ + +H+ L S + S+Y + + A + Sbjct: 126 SSIHKITRVRLANDIPMAIESSHIPFELAGELNESHFQ--SSIYDHIERYNSIPISRAKQ 183 Query: 189 NLCAGAADADDAQWLDVPVAAPLLICERIT 218 L AA ++A L + AP+L+ +R T Sbjct: 184 ELEPSAATTEEANILGIQKGAPVLLIKRTT 213 >BMEII0116 [K] COG2188 Transcriptional regulators Bme Brucella melitensis Length = 244 Score = 105 bits (261), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 70/236 (29%), Positives = 114/236 (48%), Gaps = 2/236 (0%) Query: 13 PRYRWLADIIRDTIDRGLFTDNQALPPERELAEHYEVSRDTVRKALRYMEERGIIYSDHG 72 P Y + + I +G+F LPPE L E + VSR TVRKA+ + RG++ G Sbjct: 9 PLYAKVEAALAAEIAKGIFPRGSRLPPEDSLIERFGVSRTTVRKAIENLVMRGLVEIRRG 68 Query: 73 RGTFVSPAIVRGTTRFIDSFSQDTGNRGGVPGQRIISIENVGASMAIATLLNIESGTPLV 132 +GTFV+ +R + F +D G P ++ +V A +A L + GT + Sbjct: 69 KGTFVAEPKIRQELTELSGFVEDMVALGRKPTANLLDKRSVPACEEVAEHLGVAVGTQVY 128 Query: 133 RVRRVRLIDDAPVGVHDAHLVLPRGSRLTRSQIERSGSLYKLLTAQYGFDPAEAVENLCA 192 R+ RVRL D + + +L L G ++ + +E ++ LL +YG EA L A Sbjct: 129 RIERVRLADGVAMSFDETYLPLDIGEKIASNDLEVE-PIFSLLENKYGMPLVEADYQLEA 187 Query: 193 GAADADDAQWLDVPVAAPLLICERITLSDRRQPIEYCLMKYVSSY-RYRTRIARHS 247 AD AQ L + +P+ + ER T +P++Y + Y ++ TR++R + Sbjct: 188 VTADDHVAQALGIAPGSPIFLIERTTYCKGSEPVDYEKLYYRGDLIKFCTRLSRRT 243 >BMEII0383 [K] COG2188 Transcriptional regulators Bme Brucella melitensis Length = 255 Score = 103 bits (256), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 79/223 (35%), Positives = 115/223 (51%), Gaps = 7/223 (3%) Query: 13 PRYRWLADIIRDTIDRGLFTDNQALPPERELAEHYEVSRDTVRKALRYMEERGIIYSDHG 72 P YR LA I+ + I+ G LPPER+LAE + R TVRKA + + +G + S G Sbjct: 23 PLYRSLARILGELIEEGQLAPAVGLPPERDLAEQLGIGRITVRKAYKELLTQGFVESRRG 82 Query: 73 RGTFVSPAIVRGTTRF--IDSFSQDTGNRGGVPGQRIISIENVGASMAIATLLNIESGTP 130 GTFV+ VR + + SFSQD +RG PG R+++ S A L I Sbjct: 83 SGTFVAERPVRISQHLWRLTSFSQDMISRGKEPGARVVTNRIDKPSPDEAFRLGIGVDAS 142 Query: 131 LVRVRRVRLIDDAPVGVHDAHLVLPRGSRLTRSQIERSGSLYKLLTAQYGFDPAEAVENL 190 +VR+ R+RL D P+ A V+PR L + +++ + SLY+ L A+ G P A++ L Sbjct: 143 VVRLDRLRLADGVPMAFERA--VVPR-HYLDQDRVDET-SLYEAL-ARRGHKPVRALQRL 197 Query: 191 CAGAADADDAQWLDVPVAAPLLICERITLSDRRQPIEYCLMKY 233 A D A L V AP L+ ER++ + + +EY Y Sbjct: 198 TAVTLDPGTAHLLGVHHGAPALLIERVSHLEDDRIVEYTRSHY 240 >PA2299 [K] COG2188 Transcriptional regulators Pae Pseudomonas aeruginosa Length = 249 Score = 101 bits (252), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 72/248 (29%), Positives = 124/248 (50%), Gaps = 4/248 (1%) Query: 1 MKKDLPQSEAQLPRYRWLADIIRDTIDRGLFTDNQALPPERELAEHYEVSRDTVRKALRY 60 M K LP S +P Y L +++R I G++ +P E EL + ++VSR TVR+AL Sbjct: 1 MGKLLPLSP--VPLYSQLKELLRGRILDGVYPPLSRMPSENELGKAFDVSRITVRQALGD 58 Query: 61 MEERGIIYSDHGRGTFVSPAIVRGTTRFIDSFSQDTGNRGGVPGQRIISIENVGASMAIA 120 +++ G+I+ HG+GTFV+ + + G R+ + V A +A Sbjct: 59 LQKEGLIFKIHGKGTFVARPKAFQNVSTLQGLGESMTQMGYEVINRLHGLRYVPAGARVA 118 Query: 121 TLLNIESGTPLVRVRRVRLIDDAPVGVHDAHLVLPRGSRLTRSQIERSGSLYKLLTAQYG 180 L +E G+P+ ++RVRL++ PV + +L G RL ++ + + ++ +L G Sbjct: 119 ERLRVEEGSPVCEIKRVRLVNREPVSLEVTYLPQALGERLEKADLV-TRDIFLILENDCG 177 Query: 181 FDPAEAVENLCAGAADADDAQWLDVPVAAPLLICERITLSDRRQPIEYCLMKYVS-SYRY 239 A + A ADAD + L V AP++ ER+T + P+++ + Y +++Y Sbjct: 178 IPLGHADLAIDAVLADADLTRALAVEEGAPIMRIERLTHAADGAPLDFEYLYYRGDAFQY 237 Query: 240 RTRIARHS 247 R RI R Sbjct: 238 RLRIDRQK 245