BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.2310.p (423 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2091 [GEPR] COG0477 Permeases of the major facilitator superfa... 128 2e-29 PA2589 [GEPR] COG0477 Permeases of the major facilitator superfa... 107 4e-23 BH2694 [GEPR] COG0477 Permeases of the major facilitator superfa... 94 7e-19 BS_ybfB [GEPR] COG0477 Permeases of the major facilitator superf... 88 4e-17 AGl3235 [GEPR] COG0477 Permeases of the major facilitator superf... 82 2e-15 >PA2091 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 427 Score = 128 bits (322), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 123/387 (31%), Positives = 190/387 (49%), Gaps = 12/387 (3%) Query: 25 VVLASMVALMFGPSTVAVLSLGLFIRPLEADFGWSRTQIALASSIVSYTVMLISPIQGYL 84 V+LAS+V ++FGP+ + + S LFI P+ AD W R Q AL +++ V L SP++G+L Sbjct: 29 VLLASVVGVIFGPTGLVISSFSLFIEPIAADLDWDRGQSALPVTLLGLAVALSSPLKGWL 88 Query: 85 TDRFGARAVIVPCIPLFCVAVGLMYFMPPVPWIYYAAWIALPVIGIGIFPLSYLRVVSSW 144 DR+GARA+++P + + + W Y + L ++ G P Y R++ W Sbjct: 89 VDRWGARALVLPLTAALALCLASLALARS-GWQLYLLFALLGLLTPGNIP--YARILGGW 145 Query: 145 FDKRLGLAIGIANAGIGIGGAVIPLLIGAVIAHQGWRAGFV--GLSALVALTLPLAYAFI 202 F++R G A GI G G+GG + L A I GWRA F+ GL + L F Sbjct: 146 FERRRGAAYGILGLGFGVGGPLALYLGSACIDAFGWRATFLVYGLLEGLLALPLLYALF- 204 Query: 203 REKPGTEPKKGRV--QTVPGVDFKTALRSREFKLLIGIFLLLGVIN-TALIVHQMPMLMD 259 RE+PG P+ R +PG A RS +F L++G L+LGV T ++VH +P+L + Sbjct: 205 RERPGDLPQARRTPADALPGATPGQAWRSADFWLIVGN-LILGVFAVTGVMVHGVPLLQE 263 Query: 260 AGVTPQRAAMVQATFGIFVIAGRLLTGLLIDYISAVLVMCFLVLGGTIACSLYAYGVTGN 319 G++ + A V A + +I + G L+D + L + L G Sbjct: 264 RGLSREVATDVLAALWVGMIVSQPALGYLLDRYDTPRIALPFALLAALGLLLLLLGGPPA 323 Query: 320 VVFLCAALLGMVLGAEFDVLSYLLKRYFGMRAFGKLYGVIFS-VFQFGAGAGAALLPLMR 378 +++ L+G+ G E Y + RYFG+R F +YG I F G+ LL Sbjct: 324 LLWGAVFLIGLGAGGETGTTQYFVSRYFGLRHFSVIYGSIQPFTFAIAISLGSWLLGYFY 383 Query: 379 QASGSYRSGLTTFAIATLTCALLLIVL 405 +GSY +G T + A L+V+ Sbjct: 384 DRAGSY-AGSTLVLLGAFGVAAGLLVM 409 >PA2589 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 404 Score = 107 bits (268), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 100/345 (28%), Positives = 173/345 (50%), Gaps = 18/345 (5%) Query: 25 VVLASMVALMFGPSTVAVLSLGLFIRPLEADFGWSRTQIALASSIVSYTVMLISPIQGYL 84 V+LAS+VA+M GP+ + + + LFI P+ A++ W R +++L ++ V + SP++G+L Sbjct: 13 VLLASVVAIMLGPTGILLNTFSLFIAPMSAEYAWDRAEVSLLVTLFGLAVAITSPLKGWL 72 Query: 85 TDRFGARAVIVP-----CIPLFCVAVGLMYFMPPVPWIYYAAWIALPVIGIGIFPLSYLR 139 DR+GAR ++ +PL +A W YA ++ + ++ G P Y R Sbjct: 73 IDRWGARRTMLGLTAALSLPLLGLAA------VNAVWQLYALFLLIGLLAPGNLP--YGR 124 Query: 140 VVSSWFDKRLGLAIGIANAGIGIGGAVIPLLIGAVIAHQGWRAGFV--GLSALVALTLPL 197 ++ WF +RLG+A G+ G G+GG + L+ + GWR F+ G+ L L Sbjct: 125 ILGLWFRQRLGVAYGLLGLGFGVGGPLGLLVGHQSLEAWGWRGAFLVYGVLELGLALPLL 184 Query: 198 AYAFIREKPGTEPKKGRV---QTVPGVDFKTALRSREFKLLIGIFLLLGVINTALIVHQM 254 A+ F P G + G A RS F L++G +L + + ++ H + Sbjct: 185 AWLFREPAPDAGVAAGTAVAETALSGSTAPQAWRSASFWLVLGNQVLAVFVMSGIMTHGV 244 Query: 255 PMLMDAGVTPQRAAMVQATFGIFVIAGRLLTGLLIDYISAVLVMCFLVLGGTIACSLYAY 314 PML++ G++ A + + ++ + L G L+D ++ V L + + + Sbjct: 245 PMLVERGLSRGEAGTALSALWVGMMLSQPLMGWLLDRVATPRVALPFALAAVLGMAWFLV 304 Query: 315 GVTGNVVFLCAALLGMVLGAEFDVLSYLLKRYFGMRAFGKLYGVI 359 G T + ++L L+G+ G E YLL RYFG+R+FG +YG I Sbjct: 305 GDTPSGLWLAVFLVGLGGGGESGTTKYLLMRYFGLRSFGVIYGSI 349 >BH2694 [GEPR] COG0477 Permeases of the major facilitator superfamily Bha Bacillus halodurans Length = 418 Score = 93.6 bits (231), Expect = 7e-19, Method: Compositional matrix adjust. Identities = 107/386 (27%), Positives = 176/386 (45%), Gaps = 23/386 (5%) Query: 20 YRGWVVVLASMVALMFGPSTVAVLSLGLFIRPLEADFGWSRTQIALASSIVSYTVMLIS- 78 + GW++V + L F LS G F++P E +F R I+L S++ S+ V IS Sbjct: 6 HYGWIIVAVTF--LTFLAVQGVRLSFGAFVQPWETEFSMDRGSISLISTL-SFIVYGISQ 62 Query: 79 PIQGYLTDRFGARAVIVPCIPLFCVAVGLMYFMPPVPWIYYAAWIALPVIGIGIFP-LSY 137 P+ G L DR GAR I+ C L ++ M PW + + + IG+G ++ Sbjct: 63 PLIGKLVDRLGAR-FILSCSTLLVGVSFVLTTMATQPWHLFILYGVVVSIGVGGASNVAA 121 Query: 138 LRVVSSWFDKRLGLAIGIANAGIGIGGAVIPLLIGAVIAHQ--GWRAGFVGLSALVA-LT 194 V+++WF+K+ GLA GI AG G G + L+ G+++ Q W+A V L +A + Sbjct: 122 TVVITNWFNKKRGLAFGIIEAGFGAGQMI--LVPGSLMLIQWLDWKATVVILGFFLAVIV 179 Query: 195 LPLAYAFIREKPGT---EP-----KKGRVQTVPG-VDFK--TALRSREFKLLIGIFLLLG 243 P+ +R P EP ++ T P F + R R F L+ F + G Sbjct: 180 FPIVLLLLRNHPSEKQVEPIGGVREEEETNTSPNSATFSNWSVFRMRPFWFLVLPFAICG 239 Query: 244 VINTALI-VHQMPMLMDAGVTPQRAAMVQATFGIFVIAGRLLTGLLIDYISAVLVMCFLV 302 T L+ H +P+ D G + + + F I G LL+G++ D S+ + L Sbjct: 240 FTTTGLMDTHLIPLSHDHGFSTSVTSAAVSLLAGFNIVGILLSGVIADRWSSRKFLFLLY 299 Query: 303 LGGTIACSLYAYGVTGNVVFLCAALLGMVLGAEFDVLSYLLKRYFGMRAFGKLYGVIFSV 362 + ++ + + ++ A L G+V A L +YF + G + G +F Sbjct: 300 VARALSLVILVHSHDPLLLLGFAILFGLVDFATVAPTQLLATQYFKRYSIGLMIGWLFLS 359 Query: 363 FQFGAGAGAALLPLMRQASGSYRSGL 388 Q G+ GA + L+ + +GSY L Sbjct: 360 HQVGSALGAYVPGLLYEQTGSYTVSL 385 >BS_ybfB [GEPR] COG0477 Permeases of the major facilitator superfamily Bsu Bacillus subtilis Length = 416 Score = 87.8 bits (216), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 106/358 (29%), Positives = 159/358 (44%), Gaps = 20/358 (5%) Query: 43 LSLGLFIRPLEADFGWSRTQIALASSIVSYTVMLIS-PIQGYLTDRFGARAVIVPCIPLF 101 LS G F+ P E F R+ I+L S+ VS+ V IS P+ G L D++GARAV+ L Sbjct: 26 LSFGAFVEPWERQFSIDRSTISLIST-VSFIVYGISQPVIGRLVDKWGARAVLAWSALLT 84 Query: 102 CVAVGLMYFMPPVPW---IYYAAWIALPVIGIGIFPLSYLRVVSSWFDKRLGLAIGIANA 158 V++ L Y + PW + Y ++L V G S L V +WF K+ GLA GI A Sbjct: 85 GVSIFLTYLVTS-PWQLFLLYGLGVSLGVGGASNVAASVL--VVNWFSKKRGLAFGIMEA 141 Query: 159 GIGIGGAVIPLLIGAVIAHQGWRAGFVGLSALVALT-LPLAYAFIREKP---GTEPKKGR 214 G G G ++ +I W+ V L L+ + P A +R P TEP G Sbjct: 142 GFGAGQMLLVPGSLMLIHWFSWKLTVVVLGLLLIVIVFPAALLMLRNNPSEKNTEPIGGL 201 Query: 215 VQTVPGVDFKTA-------LRSREFKLLIGIFLLLGVINTALI-VHQMPMLMDAGVTPQR 266 + KT R R+F LI FL+ G L+ H +P D G + Sbjct: 202 AASEKETAPKTTALSVAGMFRMRQFWFLIFPFLICGFTTVGLMDTHLIPFSHDHGFSTTV 261 Query: 267 AAMVQATFGIFVIAGRLLTGLLIDYISAVLVMCFLVLGGTIACSLYAYGVTGNVVFLCAA 326 + + F IAG LL+G++ D S+ ++C L ++ + Y ++ A Sbjct: 262 TSAAVSLLAGFNIAGILLSGIVADRWSSRKILCILYAVRALSIVILIYSHEPYLLLAFAI 321 Query: 327 LLGMVLGAEFDVLSYLLKRYFGMRAFGKLYGVIFSVFQFGAGAGAALLPLMRQASGSY 384 L G+V A L +YF + G + G + Q G+ GA + ++ +G Y Sbjct: 322 LFGLVDFATVAPTQMLATQYFQNYSIGLMIGWLSLAHQIGSALGAYVPGVIYTVTGEY 379 >AGl3235 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 433 Score = 82.4 bits (202), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 82/309 (26%), Positives = 129/309 (41%), Gaps = 24/309 (7%) Query: 1 MNTLPGGVPAPVVGEDSWRYRGWVVVLASMVALMFGPSTVAVLSLGLFIRPLEADFGWSR 60 MN L + + + G + + GWVV + + + ++ + A+ S G+ I+PL +FGW Sbjct: 1 MNMLSTRLASWMAGRN--LHYGWVVAVTTFLTML--ATAGAMGSAGVMIQPLHQEFGWDI 56 Query: 61 TQIALASSIVSYTVMLISPIQGYLTDRFGARAVIVPCIPLFCVAVGLMYFMPPVPWIYYA 120 I+ A ++ L+ P + FG R V+ + L + +FM V W Sbjct: 57 ADISSAMAVRLVLFGLLGPFAAAFMNHFGIRQVVSTALALIMGGIVASFFMTQV-WQLLL 115 Query: 121 AWIALPVIGIGIFPLSY-LRVVSSWFDKRLGLAIGIANAGIGIGGAVIPLLIGAVIAHQG 179 W + +G G+ L V S WF KR GL IG+ A G V L+ A+ G Sbjct: 116 LWGVVIGVGTGMTALVLGATVASRWFSKRRGLVIGLMTASNATGQLVFLPLLAALTEAYG 175 Query: 180 WRAGFVGLSALVALTLPLAYAFIREKPG------------TEPKKGRVQTV-----PGVD 222 WR A++A + L +R+ P ++P K + P V Sbjct: 176 WRTALTLSVAVIAAAMILVLLLMRDHPSDVGLPAYGETAVSKPPKQDHNLLATLASPLVT 235 Query: 223 FKTALRSREFKLLIGIFLLLGVINTALI-VHQMPMLMDAGVTPQRAAMVQATFGIFVIAG 281 K+ + F +L G F + G+ LI H + + D G+ AA A GIF G Sbjct: 236 LKSVSGNPVFWVLFGTFFVCGLSTNGLIQTHWISICGDFGMAAVTAAGTLAVIGIFDFFG 295 Query: 282 RLLTGLLID 290 + G L D Sbjct: 296 TIFAGWLSD 304