BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.2308.p (628 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ML0842 [E] COG0520 Selenocysteine lyase Mle Mycobacterium leprae 566 e-161 BMEI1039 [E] COG0520 Selenocysteine lyase Bme Brucella melitensis 414 e-115 mlr0021 [E] COG0520 Selenocysteine lyase Mlo Mesorhizobium loti 410 e-114 STM1373 [E] COG0520 Selenocysteine lyase Sty Salmonella typhimur... 403 e-112 csdB [E] COG0520 Selenocysteine lyase Eco Escherichia coli K12 400 e-111 >ML0842 [E] COG0520 Selenocysteine lyase Mle Mycobacterium leprae Length = 411 Score = 567 bits (1460), Expect = e-161, Method: Compositional matrix adjust. Identities = 267/400 (66%), Positives = 322/400 (80%) Query: 223 FDVHAVRRDFSILQERVNGRPLVWFDNAATTHKPQAVIDRISEFYRRENSNIHRAAHELA 282 FD+ AVR DF ILQE VNG+PL+WFDNAATT KPQ VIDR+S FY ENSNIHRAAHELA Sbjct: 5 FDIQAVRADFPILQETVNGKPLIWFDNAATTQKPQVVIDRLSYFYAHENSNIHRAAHELA 64 Query: 283 ARATDAYEGARERVRAFLNAPDVNEVIFVRGTTEAINLVAKSWGGKHVGAGDEIIVSHLE 342 ARATDAYE ARE R F+ A E+IFVRGTTEAINLVA +WGGKH+ GDE++++HLE Sbjct: 65 ARATDAYEEARETARRFIGAAKAQEIIFVRGTTEAINLVAYAWGGKHLQPGDEVVITHLE 124 Query: 343 HHANIVPWQQLAAEKGAKLRVIPVDDSGQVLLDEYAKLLNERTRIVAVTQVSNALGTVTP 402 HHANIVPWQ L+++ GA L+V PVDD+G +L+ E+ LL RT++VA TQVSNALGTVT Sbjct: 125 HHANIVPWQLLSSQTGAILKVAPVDDAGNLLMSEFEDLLGPRTKLVAATQVSNALGTVTQ 184 Query: 403 TKQIVELARLAGARTLVDGAQSVSHMRTDVQALGADFFVFSGHKVFGPTGIGALWGRREV 462 ++IVEL GAR L+DGAQS+ H+ +V LGADFFVFSGHK++GPTGIG L+G +V Sbjct: 185 GEKIVELGHRYGARVLIDGAQSIPHLPINVSELGADFFVFSGHKIYGPTGIGVLYGCEDV 244 Query: 463 LEDMPPWQGGGNMIADVTFEKTIFQPLPNTFEAGTGNIADAVGLGAAIDYVNRIGIDNIA 522 L +MPPWQGGGNMI DVT E++++Q PN FEAGTGNIADAVGLG A+ YV R+G+ IA Sbjct: 245 LTEMPPWQGGGNMIVDVTLERSLYQGPPNKFEAGTGNIADAVGLGEALRYVERVGVQRIA 304 Query: 523 SYEHALLEYGMHKLGEVDGLRLIGTAAHKASVMSFVLDGYSTEEVGKALNQEGIAVRTGH 582 S+E ALL+Y +L ++ G+RL+GTA KASV+SFVL G+ EVGKALN EGIAVR GH Sbjct: 305 SHEQALLDYATPRLADIPGVRLVGTATEKASVLSFVLAGHEPLEVGKALNAEGIAVRAGH 364 Query: 583 HCAQPILRRFGVETTVRPSLAFYNTFEEIDCLLTVVRRLS 622 HCAQP+LRR G+E TVRPS AFYNT+EEID + VVRR++ Sbjct: 365 HCAQPVLRRLGLEATVRPSFAFYNTYEEIDVFINVVRRIA 404 >BMEI1039 [E] COG0520 Selenocysteine lyase Bme Brucella melitensis Length = 436 Score = 414 bits (1063), Expect = e-115, Method: Compositional matrix adjust. Identities = 198/395 (50%), Positives = 273/395 (69%) Query: 220 TAAFDVHAVRRDFSILQERVNGRPLVWFDNAATTHKPQAVIDRISEFYRRENSNIHRAAH 279 T A+DV A+RRDF IL +V+G+ LV+ DN A+ KPQ+VID ++ Y E +N+HR H Sbjct: 30 TMAYDVEAIRRDFPILSRQVHGKTLVYLDNGASAQKPQSVIDAVTHAYANEYANVHRGLH 89 Query: 280 ELAARATDAYEGARERVRAFLNAPDVNEVIFVRGTTEAINLVAKSWGGKHVGAGDEIIVS 339 L+ ATDAYE +RE VR FLNA V+E++F + TEAIN VA +G +G GDEI++S Sbjct: 90 FLSNAATDAYEKSRETVRRFLNAGSVDEIVFTKNATEAINTVAYGYGMPFIGEGDEILLS 149 Query: 340 HLEHHANIVPWQQLAAEKGAKLRVIPVDDSGQVLLDEYAKLLNERTRIVAVTQVSNALGT 399 +EHH+NIVPW + +GAKL PVDD+G ++E+ K L+ERT++VA+T +SN LGT Sbjct: 150 IMEHHSNIVPWHFIRERQGAKLVFTPVDDNGVFHIEEFEKRLSERTKLVAITHMSNTLGT 209 Query: 400 VTPTKQIVELARLAGARTLVDGAQSVSHMRTDVQALGADFFVFSGHKVFGPTGIGALWGR 459 V P K+IVELA G LVDG+Q H+ DVQ LG D++VF+GHKV+GP+GIG L+GR Sbjct: 210 VVPIKKIVELAHARGVPVLVDGSQGAVHLPVDVQDLGCDWYVFTGHKVYGPSGIGVLYGR 269 Query: 460 REVLEDMPPWQGGGNMIADVTFEKTIFQPLPNTFEAGTGNIADAVGLGAAIDYVNRIGID 519 ++LE M P+QGGG MI +VT E + P+ FEAGT I A+GLGAA++Y+ +IG Sbjct: 270 AQMLEKMRPFQGGGEMIEEVTEENVTYNHPPHRFEAGTPPIVQAIGLGAALEYMEKIGRH 329 Query: 520 NIASYEHALLEYGMHKLGEVDGLRLIGTAAHKASVMSFVLDGYSTEEVGKALNQEGIAVR 579 I ++E L +Y +LG ++ LR+ G A K +++SF L+G +V +++ G+AVR Sbjct: 330 AILAHEADLRDYAHERLGRINSLRIFGNAPDKGAIISFALEGIHAHDVSMVIDRAGVAVR 389 Query: 580 TGHHCAQPILRRFGVETTVRPSLAFYNTFEEIDCL 614 G HCAQP+L+RFGV +T R S A YNT E+D L Sbjct: 390 AGTHCAQPLLKRFGVTSTCRASFALYNTRAEVDAL 424 >mlr0021 [E] COG0520 Selenocysteine lyase Mlo Mesorhizobium loti Length = 413 Score = 410 bits (1053), Expect = e-114, Method: Compositional matrix adjust. Identities = 197/396 (49%), Positives = 268/396 (67%) Query: 219 QTAAFDVHAVRRDFSILQERVNGRPLVWFDNAATTHKPQAVIDRISEFYRRENSNIHRAA 278 +T +DV A+RRDF IL V G+PLV+ DN A+ KPQ V+D I Y +E +N+HR Sbjct: 6 ETTPYDVEAIRRDFPILSREVYGKPLVYLDNGASAQKPQVVLDTIQHAYSQEYANVHRGL 65 Query: 279 HELAARATDAYEGARERVRAFLNAPDVNEVIFVRGTTEAINLVAKSWGGKHVGAGDEIIV 338 H L+ ATDAYE ARE VR FLNAP + ++F TT AIN VA +G ++G GDEI++ Sbjct: 66 HFLSNAATDAYEKARETVRRFLNAPSTDNIVFTSNTTSAINTVAYGYGMPNIGEGDEIVL 125 Query: 339 SHLEHHANIVPWQQLAAEKGAKLRVIPVDDSGQVLLDEYAKLLNERTRIVAVTQVSNALG 398 S +EHH+NIVPW + +GAKL +PVDD G ++E+ K L RT++VA+TQ+SNALG Sbjct: 126 SIMEHHSNIVPWHFIRERQGAKLVWVPVDDLGVFHIEEFEKRLTNRTKLVAITQMSNALG 185 Query: 399 TVTPTKQIVELARLAGARTLVDGAQSVSHMRTDVQALGADFFVFSGHKVFGPTGIGALWG 458 TVTP K+IV +A G LVDG+QS HM DVQ L DFFVF+GHKV+GP+GIG L+G Sbjct: 186 TVTPIKEIVRIAHARGIPVLVDGSQSAVHMPIDVQDLDCDFFVFTGHKVYGPSGIGVLYG 245 Query: 459 RREVLEDMPPWQGGGNMIADVTFEKTIFQPLPNTFEAGTGNIADAVGLGAAIDYVNRIGI 518 ++++L M P+ GGG MI +VT + + P+ FEAGT I A+GLGAA+DY+ +IG Sbjct: 246 KKDILAGMRPFMGGGEMIEEVTEDIVTYNEPPHRFEAGTPPIVQAIGLGAALDYMEKIGR 305 Query: 519 DNIASYEHALLEYGMHKLGEVDGLRLIGTAAHKASVMSFVLDGYSTEEVGKALNQEGIAV 578 + IA++E L Y +L ++ LR+ G A K +++SF L G +V ++++G+AV Sbjct: 306 ERIAAHEEDLKTYAHERLRAINSLRIFGDAPGKGAIISFELQGIHAHDVSMVIDRQGVAV 365 Query: 579 RTGHHCAQPILRRFGVETTVRPSLAFYNTFEEIDCL 614 R G HCAQP+L+RFGV +T R S YNT E+D L Sbjct: 366 RAGTHCAQPLLKRFGVTSTCRASFGMYNTRAEVDAL 401 >STM1373 [E] COG0520 Selenocysteine lyase Sty Salmonella typhimurium LT2 Length = 406 Score = 403 bits (1036), Expect = e-112, Method: Compositional matrix adjust. Identities = 203/403 (50%), Positives = 268/403 (66%), Gaps = 5/403 (1%) Query: 223 FDVHAVRRDFSILQERVNGRPLVWFDNAATTHKPQAVIDRISEFYRRENSNIHRAAHELA 282 F V VR DF ILQ VNG PL + D+AA+ KP VID S FYR + +HR H L+ Sbjct: 3 FPVEKVRADFPILQREVNGLPLAYLDSAASAQKPNQVIDAESAFYRHGYAAVHRGIHTLS 62 Query: 283 ARATDAYEGARERVRAFLNAPDVNEVIFVRGTTEAINLVAKSWGGKHVGAGDEIIVSHLE 342 A+AT++ E R++ F+NA E++FVRGTTE INLVA SWG +++ AGD II+S +E Sbjct: 63 AQATESMENVRKQASRFINARSAEELVFVRGTTEGINLVANSWGTENIRAGDNIIISEME 122 Query: 343 HHANIVPWQQLAAEKGAKLRVIPVDDSGQVLLDEYAKLLNERTRIVAVTQVSNALGTVTP 402 HHANIVPWQ L KGA+LRVIP+ G + L+ A L ++RTR++A+T VSN LGT P Sbjct: 123 HHANIVPWQMLCERKGAELRVIPLHPDGTLRLETLAALFDDRTRLLAITHVSNVLGTENP 182 Query: 403 TKQIVELARLAGARTLVDGAQSVSHMRTDVQALGADFFVFSGHKVFGPTGIGALWGRREV 462 ++ LAR GA+ LVDGAQ+V H DVQAL DF+VFSGHK++GPTGIG L+ + + Sbjct: 183 LPDMIALARQHGAKVLVDGAQAVMHHAVDVQALDCDFYVFSGHKLYGPTGIGILYVKEAL 242 Query: 463 LEDMPPWQGGGNMIADVTFEK-TIFQPLPNTFEAGTGNIADAVGLGAAIDYVNRIGIDNI 521 L++MPPW+GGG+MI+ V+ + T + P FEAGT N +GLGAAIDYV +G+D I Sbjct: 243 LQEMPPWEGGGSMISTVSLTQGTTWAKAPWRFEAGTPNTGGIIGLGAAIDYVTSLGLDKI 302 Query: 522 ASYEHALLEYGMHKLGEVDGLRLIGTAAHKASVMSFVLDGYSTEEVGKALNQEGIAVRTG 581 YE L+ Y + +L +V + L G A + V++F L + +VG L+ GIAVRTG Sbjct: 303 GDYEQMLMRYALEQLAQVPDITLYG-PAQRLGVIAFNLGKHHAYDVGSFLDNYGIAVRTG 361 Query: 582 HHCAQPILRRFGVETTVRPSLAFYNTFEEIDCL---LTVVRRL 621 HHCA P++ +GV R SLA YNT EE+D L LT + RL Sbjct: 362 HHCAMPLMAWYGVPAMCRASLAMYNTHEEVDRLVAGLTRIHRL 404 >csdB [E] COG0520 Selenocysteine lyase Eco Escherichia coli K12 Length = 406 Score = 400 bits (1028), Expect = e-111, Method: Compositional matrix adjust. Identities = 199/400 (49%), Positives = 268/400 (67%), Gaps = 2/400 (0%) Query: 223 FDVHAVRRDFSILQERVNGRPLVWFDNAATTHKPQAVIDRISEFYRRENSNIHRAAHELA 282 F V VR DF +L VNG PL + D+AA+ KP VID +EFYR + +HR H L+ Sbjct: 3 FSVDKVRADFPVLSREVNGLPLAYLDSAASAQKPSQVIDAEAEFYRHGYAAVHRGIHTLS 62 Query: 283 ARATDAYEGARERVRAFLNAPDVNEVIFVRGTTEAINLVAKSWGGKHVGAGDEIIVSHLE 342 A+AT+ E R+R F+NA E++FVRGTTE INLVA SWG +V AGD II+S +E Sbjct: 63 AQATEKMENVRKRASLFINARSAEELVFVRGTTEGINLVANSWGNSNVRAGDNIIISQME 122 Query: 343 HHANIVPWQQLAAEKGAKLRVIPVDDSGQVLLDEYAKLLNERTRIVAVTQVSNALGTVTP 402 HHANIVPWQ L A GA+LRVIP++ G + L+ L +E+TR++A+T VSN LGT P Sbjct: 123 HHANIVPWQMLCARVGAELRVIPLNPDGTLQLETLPTLFDEKTRLLAITHVSNVLGTENP 182 Query: 403 TKQIVELARLAGARTLVDGAQSVSHMRTDVQALGADFFVFSGHKVFGPTGIGALWGRREV 462 +++ LA GA+ LVDGAQ+V H DVQAL DF+VFSGHK++GPTGIG L+ + + Sbjct: 183 LAEMITLAHQHGAKVLVDGAQAVMHHPVDVQALDCDFYVFSGHKLYGPTGIGILYVKEAL 242 Query: 463 LEDMPPWQGGGNMIADVTF-EKTIFQPLPNTFEAGTGNIADAVGLGAAIDYVNRIGIDNI 521 L++MPPW+GGG+MIA V+ E T + P FEAGT N +GLGAA++YV+ +G++NI Sbjct: 243 LQEMPPWEGGGSMIATVSLSEGTTWTKAPWRFEAGTPNTGGIIGLGAALEYVSALGLNNI 302 Query: 522 ASYEHALLEYGMHKLGEVDGLRLIGTAAHKASVMSFVLDGYSTEEVGKALNQEGIAVRTG 581 A YE L+ Y + +L V L L G ++ V++F L + +VG L+ GIAVRTG Sbjct: 303 AEYEQNLMHYALSQLESVPDLTLYG-PQNRLGVIAFNLGKHHAYDVGSFLDNYGIAVRTG 361 Query: 582 HHCAQPILRRFGVETTVRPSLAFYNTFEEIDCLLTVVRRL 621 HHCA P++ + V R SLA YNT EE+D L+T ++R+ Sbjct: 362 HHCAMPLMAYYNVPAMCRASLAMYNTHEEVDRLVTGLQRI 401