BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.2293.p (325 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value aq_091m [KT] COG3829 Transcriptional regulator containing PAS, A... 257 3e-68 PA4726 [T] COG2204 Response regulator containing CheY-like recei... 246 4e-65 RSc0332 [T] COG2204 Response regulator containing CheY-like rece... 239 7e-63 atoC [T] COG2204 Response regulator containing CheY-like receive... 238 1e-62 CAC3088_2 [KT] COG3829 Transcriptional regulator containing PAS,... 236 4e-62 >aq_091m [KT] COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Aae Aquifex aeolicus Length = 530 Score = 257 bits (656), Expect = 3e-68, Method: Compositional matrix adjust. Identities = 131/312 (41%), Positives = 192/312 (61%), Gaps = 11/312 (3%) Query: 6 RLHMIGSSPQMERVDAQLRKMASVEATVLIEGETGTGKELAARAIHYLGPRRDKPFIPIN 65 +L ++ SP+ +V +++ ++ + VLI GETGTGK L AR IHYL PRRDKPF+ IN Sbjct: 228 KLKIVTKSPKFLKVLEKVKTISEMNVNVLITGETGTGKSLLARYIHYLSPRRDKPFVKIN 287 Query: 66 CGALPEQLIESELFGHERGAFTDAKSAAPGLVADADGGTLFLDEVDALNYKAQTAILRFL 125 CGA+PE L+E+ LFG+ +GAFT A ++ PG V A+GGTLFLDE+ L Q +L + Sbjct: 288 CGAIPENLLEAXLFGYNKGAFTGAIASKPGKVEMANGGTLFLDEIGELPLHLQVKLLGLI 347 Query: 126 QDHTYRRVGSGVTRKANVRIVAATNNRLNALVETGRFRRDLMYRLNVLSINLPPLRERGN 185 QD + R+G RKA+VRI+AATN L LVE G+FR DL YRLNV+++ LPPLRER Sbjct: 348 QDKEFERIGDLKPRKADVRIIAATNKNLKKLVEEGKFREDLYYRLNVVNVELPPLRERKE 407 Query: 186 DAVEMAQAFLSRFAHQYRMPDRRLHASALDFIAQYDWPGNIRELENMMHREFLMSDTTDI 245 D + FL +F+ + + + A+ + +YD+PGN+RELEN + ++S T+ I Sbjct: 408 DIPHLVSYFLEKFSKIHGKKVKGVSPEAMKLLLEYDYPGNVRELENAIEHAVVVSSTSLI 467 Query: 246 YLGTQRPVQGSAD--EDVVQFKPMKEKMIHDFERRYVRDVLTRVDGNLTRAAKLAGQERS 303 G D E++ +K+K + E +++ L R GN + AAKL G R+ Sbjct: 468 ---------GPDDLPEEIRIGSKVKKKFRENEELEKIKEALERAGGNKSLAAKLLGIHRT 518 Query: 304 AFGKLARKHGLS 315 + +++GL+ Sbjct: 519 TLWRKLKEYGLA 530 >PA4726 [T] COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Pae Pseudomonas aeruginosa Length = 478 Score = 246 bits (629), Expect = 4e-65, Method: Compositional matrix adjust. Identities = 124/239 (51%), Positives = 168/239 (70%), Gaps = 2/239 (0%) Query: 9 MIGSSPQMERVDAQLRKMASVEATVLIEGETGTGKELAARAIHYLGPRRDKPFIPINCGA 68 +IGS M+ + +++RK+A ++TVLI+GE+GTGKEL ARA+H L R P I +NC A Sbjct: 149 IIGSCAPMQELYSKIRKVAPTDSTVLIQGESGTGKELVARALHNLSKRAKAPLISVNCAA 208 Query: 69 LPEQLIESELFGHERGAFTDAKSAAPGLVADADGGTLFLDEVDALNYKAQTAILRFLQDH 128 +PE LIESELFGHE+GAFT A + GLV ADGGTLFLDE+ L +AQ +LR LQ+ Sbjct: 209 IPETLIESELFGHEKGAFTGASAGRAGLVEAADGGTLFLDEIGELPLEAQARLLRVLQEG 268 Query: 129 TYRRVGSGVTRKANVRIVAATNNRLNALVETGRFRRDLMYRLNVLSINLPPLRERGNDAV 188 RRVGS ++K +VR++AAT+ L L +TG+FR DL YRL+V+S+ LP LRERGND + Sbjct: 269 EIRRVGSVQSQKVDVRLIAATHRDLKTLAKTGQFREDLYYRLHVISLKLPALRERGNDVM 328 Query: 189 EMAQAFLSRFAHQY-RMPDRRLHASALDFIAQYDWPGNIRELENMMHREFLMSDTTDIY 246 E+A+AFL+R + R P H A I Y WPGN+RELEN + R ++S++ +I+ Sbjct: 329 EIARAFLARQCTRMGRAPLSFAH-DAEQAIRHYPWPGNVRELENAIERAVILSESQEIH 386 >RSc0332 [T] COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Rso Ralstonia solanacearum Length = 438 Score = 239 bits (609), Expect = 7e-63, Method: Compositional matrix adjust. Identities = 134/307 (43%), Positives = 185/307 (60%), Gaps = 14/307 (4%) Query: 9 MIGSSPQMERVDAQLRKMASVEATVLIEGETGTGKELAARAIHYLGPRRDKPFIPINCGA 68 +IG S M V A + +A+ +A VLI GETGTGKEL AR++H L PR DKPFI +NCGA Sbjct: 145 IIGRSQAMASVRALIDNVAATDAPVLINGETGTGKELVARSLHTLSPRHDKPFIALNCGA 204 Query: 69 LPEQLIESELFGHERGAFTDAKSAAPGLVADADGGTLFLDEVDALNYKAQTAILRFLQDH 128 +PEQ+ ESE+FGHE GAFT A G + A GGTLFLDE++++ Q +LR LQ+ Sbjct: 205 VPEQIFESEMFGHEAGAFTGAGKRRIGKIEHASGGTLFLDEIESMPLALQVKLLRVLQEG 264 Query: 129 TYRRVGSGVTRKANVRIVAATNNRLNALVETGRFRRDLMYRLNVLSINLPPLRERGNDAV 188 R+GS + + +VRIVAA + AL+E G FRRDL YRLNV++I+LPPLRER D + Sbjct: 265 MLERLGSNASVRIDVRIVAAAKGDMEALIEAGGFRRDLYYRLNVVAIDLPPLRERREDII 324 Query: 189 EMAQAFLSRFAHQYRMPDRRLHASALDFIAQYDWPGNIRELENMMHREFLMSDTTDIYLG 248 + + FL A +Y+ P L + Q +WPGN+REL N R + LG Sbjct: 325 PLFEHFLLEAAVRYQRPLPMLSERQRHELMQSNWPGNVRELRNAADR---------LVLG 375 Query: 249 TQR-PVQGSADEDVVQFKPMKEKMIHDFERRYVRDVLTRVDGNLTRAAKLAGQERSAFGK 307 R PV A ED + P+KE+ + +ER + + L R G++ +AA + R+ Sbjct: 376 VGRTPVVSDAAEDGM---PLKER-VERYERTVIAETLARTGGSVHQAADILQVGRATLYD 431 Query: 308 LARKHGL 314 +++GL Sbjct: 432 KIKRYGL 438 >atoC [T] COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Eco Escherichia coli K12 Length = 461 Score = 238 bits (607), Expect = 1e-62, Method: Compositional matrix adjust. Identities = 128/319 (40%), Positives = 191/319 (59%), Gaps = 12/319 (3%) Query: 8 HMIGSSPQMERVDAQLRKMASVEATVLIEGETGTGKELAARAIHYLGPRRDKPFIPINCG 67 H++ +SP M + K+A +A+VLI GE+GTGKEL ARAIHY R PFI +NC Sbjct: 144 HILTNSPAMMDICKDTAKIALSQASVLISGESGTGKELIARAIHYNSRRAKGPFIKVNCA 203 Query: 68 ALPEQLIESELFGHERGAFTDAKSAAPGLVADADGGTLFLDEVDALNYKAQTAILRFLQD 127 ALPE L+ESELFGHE+GAFT A++ GL A+ GTL LDE+ + Q +LR LQ+ Sbjct: 204 ALPESLLESELFGHEKGAFTGAQTLRQGLFERANEGTLLLDEIGEMPLVLQAKLLRILQE 263 Query: 128 HTYRRVGSGVTRKANVRIVAATNNRLNALVETGRFRRDLMYRLNVLSINLPPLRERGNDA 187 + R+G T K ++RI+AATN L A+V+ G FR DL YRLNV+ + LPPLR+R D Sbjct: 264 REFERIGGHQTIKVDIRIIAATNRDLQAMVKEGTFREDLFYRLNVIHLILPPLRDRREDI 323 Query: 188 VEMAQAFLSRFAHQYRMPDRRLHASALDFIAQYDWPGNIRELENMMHREFLMSD-----T 242 +A FL +F+ + + + A+ + + WPGNIREL N++ R +M+ + Sbjct: 324 SLLANHFLQKFSSENQRDIIDIDPMAMSLLTAWSWPGNIRELSNVIERAVVMNSGPIIFS 383 Query: 243 TDIYLGTQRPVQGSADEDVVQFKPMKEKMIHD----FERRYVRDVLTRVDGNLTRAAKLA 298 D+ ++PV + + V+ P+ E+ + + E+R + +VL + +GN TR A + Sbjct: 384 EDLPPQIRQPVCNAGE---VKTAPVGERNLKEEIKRVEKRIIMEVLEQQEGNRTRTALML 440 Query: 299 GQERSAFGKLARKHGLSPS 317 G R A +++G+ P+ Sbjct: 441 GISRRALMYKLQEYGIDPA 459 >CAC3088_2 [KT] COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Cac Clostridium acetobutylicum Length = 557 Score = 236 bits (603), Expect = 4e-62, Method: Compositional matrix adjust. Identities = 115/240 (47%), Positives = 155/240 (64%) Query: 8 HMIGSSPQMERVDAQLRKMASVEATVLIEGETGTGKELAARAIHYLGPRRDKPFIPINCG 67 ++IG+S + V K A +TVLI GE+GTGKEL A+AIH PR+DKPF+ +NC Sbjct: 246 NIIGNSSSLRDVLITADKAADSTSTVLIRGESGTGKELIAKAIHNGSPRKDKPFVRVNCA 305 Query: 68 ALPEQLIESELFGHERGAFTDAKSAAPGLVADADGGTLFLDEVDALNYKAQTAILRFLQD 127 A+PE LIESELFG+E+GAFT A + PG A A+ GT+FLDE+ + Q +LR LQ+ Sbjct: 306 AIPENLIESELFGYEKGAFTGAVKSKPGKFAIANTGTIFLDEIGDIPKSMQVKLLRVLQE 365 Query: 128 HTYRRVGSGVTRKANVRIVAATNNRLNALVETGRFRRDLMYRLNVLSINLPPLRERGNDA 187 + VG T+K +VRI+AATN L +++TG FR DL YRLNVLSI LPPLR+R D Sbjct: 366 REFESVGGIETQKVDVRIIAATNRNLEEMLKTGEFREDLYYRLNVLSIFLPPLRKRKEDI 425 Query: 188 VEMAQAFLSRFAHQYRMPDRRLHASALDFIAQYDWPGNIRELENMMHREFLMSDTTDIYL 247 + + F++ + + P +++ S L Y+WPGNIRELEN++ R M D I L Sbjct: 426 NLLVEHFINNISKKLNKPVKKIEESCLSCFMNYNWPGNIRELENIIERSINMCDDGVIML 485