BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.2230.p (490 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2413 [E] COG0160 4-aminobutyrate aminotransferase and related ... 608 e-174 all0396 [E] COG0160 4-aminobutyrate aminotransferase and related... 521 e-147 SMa2400 [E] COG0160 4-aminobutyrate aminotransferase and related... 513 e-145 BH2624 [E] COG0160 4-aminobutyrate aminotransferase and related ... 498 e-140 HI0949 [E] COG0160 4-aminobutyrate aminotransferase and related ... 459 e-129 >PA2413 [E] COG0160 4-aminobutyrate aminotransferase and related aminotransferases Pae Pseudomonas aeruginosa Length = 469 Score = 608 bits (1569), Expect = e-174, Method: Compositional matrix adjust. Identities = 296/436 (67%), Positives = 353/436 (80%), Gaps = 1/436 (0%) Query: 27 YDLGTHPLLQRQARQESNARSYPRRLPLVLKRGAGIYVEDIEGRVFIDCLAGAGTLALGH 86 Y+ PLL+RQ+RQESNARSYPRR+PL LK+ G+ VED+EGR FIDCLAGAGTLALGH Sbjct: 24 YEFSQSPLLERQSRQESNARSYPRRIPLALKKARGLLVEDVEGRTFIDCLAGAGTLALGH 83 Query: 87 NHPAVIEAIVALLHDGAALHTLDLTTPVKDRFMQDLLEILPPELSRQARVQFCGPTGADA 146 NHP VIEAI +L D LHTLDLTTPVKD+F+QDL +LPP L+ +A++QFCGPTG DA Sbjct: 84 NHPVVIEAIRQVLADELPLHTLDLTTPVKDQFVQDLFGLLPPALAAEAKIQFCGPTGTDA 143 Query: 147 IEAALKLVKSATGGGTVLAFQGAYHGMTQGALQLMGSLAPKAPLNGILS-GVQFLPYPYD 205 +EAALKLV++ATG T+L+FQG YHGM+QGAL LMG+L PK PL +LS GVQFLPYPYD Sbjct: 144 VEAALKLVRTATGRSTILSFQGGYHGMSQGALGLMGNLGPKKPLGAVLSTGVQFLPYPYD 203 Query: 206 YRCPLGLGGDAGVRAGLHYIAATLNDPEGGVPKPAGVVVEAIQGEGGVIAAPPAWLAGLR 265 YRCP GLGG+AGV+A LHY+ LNDPEGGV PA V+VE +QGEGGV+ A WL GLR Sbjct: 204 YRCPFGLGGEAGVKANLHYLENLLNDPEGGVQLPAAVIVEVVQGEGGVVPADLDWLRGLR 263 Query: 266 QLTQSAEVPLILDEVQSGFGRSGKMFAFEHAGITPDVVVLSKAIGGGLPLSVVVYKEQLD 325 ++T+ A V LI+DE+QSGF R+G+MFAFEHAGI PDVVVLSKAIGG LPL+VVVY+E LD Sbjct: 264 RITEQAGVALIVDEIQSGFARTGRMFAFEHAGIVPDVVVLSKAIGGSLPLAVVVYREWLD 323 Query: 326 QWKPGAHAGTFRGNQLAMAAGSATMRVLRSEDLAGQARTKGQRLETALLALRQLHPHIGE 385 +W+PGAHAGTFRGNQ+AMAAGSA MR L+ DLA A G+RL L L++ +P +G+ Sbjct: 324 KWQPGAHAGTFRGNQMAMAAGSAVMRYLKEHDLAAHAAAMGERLAEHLRILQRDYPQLGD 383 Query: 386 VRGRGLMLGVEIIDPQAPADVLGNPAAAPALARALQHECLRRGLILELGGRHGCVVRFLP 445 +RGRGLMLGVEI+DPQ AD LG+P ALA +Q ECLRRGLILELGGRHG VVRFLP Sbjct: 384 IRGRGLMLGVEIVDPQGEADALGHPPTDGALASRVQRECLRRGLILELGGRHGSVVRFLP 443 Query: 446 PLVIGEDELERVIDIF 461 PL+IG ++++ V F Sbjct: 444 PLIIGAEQIDEVARRF 459 >all0396 [E] COG0160 4-aminobutyrate aminotransferase and related aminotransferases Nos Nostoc sp. PCC 7120 Length = 493 Score = 521 bits (1343), Expect = e-147, Method: Compositional matrix adjust. Identities = 248/434 (57%), Positives = 324/434 (74%) Query: 35 LQRQARQESNARSYPRRLPLVLKRGAGIYVEDIEGRVFIDCLAGAGTLALGHNHPAVIEA 94 L+RQ +ESNARSYPRR+ + + GIY++D +G V+IDCLAGAGTLALGHNHP IEA Sbjct: 48 LERQQARESNARSYPRRIRIAISEAQGIYLKDADGNVYIDCLAGAGTLALGHNHPVAIEA 107 Query: 95 IVALLHDGAALHTLDLTTPVKDRFMQDLLEILPPELSRQARVQFCGPTGADAIEAALKLV 154 + +L G LHTLDLTTPVKD+F++++ LP E ++ A++QFCGP+GADA+EAA+KLV Sbjct: 108 MRRVLDTGLPLHTLDLTTPVKDQFVEEIFASLPAEFAQNAKIQFCGPSGADAVEAAIKLV 167 Query: 155 KSATGGGTVLAFQGAYHGMTQGALQLMGSLAPKAPLNGILSGVQFLPYPYDYRCPLGLGG 214 K+ATG +VL+F G YHGMT GAL L G+L PK + G++ V FLPYPY YRCP GLGG Sbjct: 168 KTATGHRSVLSFHGGYHGMTHGALSLTGNLNPKQAVTGLMPDVHFLPYPYHYRCPFGLGG 227 Query: 215 DAGVRAGLHYIAATLNDPEGGVPKPAGVVVEAIQGEGGVIAAPPAWLAGLRQLTQSAEVP 274 +AG YI + L+DPE G+ PA +++E +QGEGGVI AP WL +R++T+ +P Sbjct: 228 EAGQITSSRYIESILDDPESGIVTPAAMILEVVQGEGGVIPAPDDWLREMRRITRDRHIP 287 Query: 275 LILDEVQSGFGRSGKMFAFEHAGITPDVVVLSKAIGGGLPLSVVVYKEQLDQWKPGAHAG 334 LI+DE+Q+G GR+GK++AFEH+GI PDV++LSKAIGG LPLSVV+Y + LD+W PGAHAG Sbjct: 288 LIVDEIQTGLGRTGKLYAFEHSGIVPDVLLLSKAIGGSLPLSVVLYNKALDKWSPGAHAG 347 Query: 335 TFRGNQLAMAAGSATMRVLRSEDLAGQARTKGQRLETALLALRQLHPHIGEVRGRGLMLG 394 TFRGNQ+AMAAG+AT++ + L A G RL L ++ IGEVRGRGLM+G Sbjct: 348 TFRGNQMAMAAGTATLQYILENSLTEHAAAMGDRLLKHLHQIQGETYCIGEVRGRGLMVG 407 Query: 395 VEIIDPQAPADVLGNPAAAPALARALQHECLRRGLILELGGRHGCVVRFLPPLVIGEDEL 454 VEII+PQA AD G P LA +Q ECLRRGLI+ELGGR G VVRFLPPL++ ++ Sbjct: 408 VEIINPQASADRRGKYPVHPQLASCIQAECLRRGLIVELGGRFGSVVRFLPPLIVTPAQI 467 Query: 455 ERVIDIFAQALRVA 468 + + +IF+ A++ A Sbjct: 468 DSISEIFSSAVQAA 481 >SMa2400 [E] COG0160 4-aminobutyrate aminotransferase and related aminotransferases Sme Sinorhizobium meliloti Length = 470 Score = 513 bits (1320), Expect = e-145, Method: Compositional matrix adjust. Identities = 248/431 (57%), Positives = 312/431 (72%) Query: 35 LQRQARQESNARSYPRRLPLVLKRGAGIYVEDIEGRVFIDCLAGAGTLALGHNHPAVIEA 94 L RQ R+ESNARSYPRR P+ LK +G V D++GR ++DCLAGAGTLALGHNHP VIE Sbjct: 32 LDRQERRESNARSYPRRFPVALKSASGCIVTDVDGRSYLDCLAGAGTLALGHNHPEVIET 91 Query: 95 IVALLHDGAALHTLDLTTPVKDRFMQDLLEILPPELSRQARVQFCGPTGADAIEAALKLV 154 + +L G LHTLDLTTPVKDRF+ D+ LP L +A++QFC P+G DA+EAA+KL Sbjct: 92 LQQVLGSGLPLHTLDLTTPVKDRFVSDIFGTLPAGLRDEAKIQFCSPSGTDAVEAAIKLA 151 Query: 155 KSATGGGTVLAFQGAYHGMTQGALQLMGSLAPKAPLNGILSGVQFLPYPYDYRCPLGLGG 214 K+ATG +++F+GAYHGM+QG+L LMGSL PKA + ++ G F PYPY YRCP G GG Sbjct: 152 KTATGRTDLVSFRGAYHGMSQGSLSLMGSLGPKASVGQLVPGAHFFPYPYAYRCPFGRGG 211 Query: 215 DAGVRAGLHYIAATLNDPEGGVPKPAGVVVEAIQGEGGVIAAPPAWLAGLRQLTQSAEVP 274 + Y L DPEGG+ +PA V++EA+QGEGGVI AP WL +R++T+ +P Sbjct: 212 NETATLAAEYFERALRDPEGGINRPAAVILEAVQGEGGVIPAPVEWLRAVRRVTRDLGIP 271 Query: 275 LILDEVQSGFGRSGKMFAFEHAGITPDVVVLSKAIGGGLPLSVVVYKEQLDQWKPGAHAG 334 LI+DEVQSG GR+G +AF+ AGI PDVVVLSKAIGGGLPL+VV+Y+E LD WKPGAHAG Sbjct: 272 LIVDEVQSGVGRTGSFYAFQKAGIIPDVVVLSKAIGGGLPLAVVIYREDLDLWKPGAHAG 331 Query: 335 TFRGNQLAMAAGSATMRVLRSEDLAGQARTKGQRLETALLALRQLHPHIGEVRGRGLMLG 394 TFRGNQLAMAAGS T+ ++ E L +A G+RL L + P+IGEVRG GLMLG Sbjct: 332 TFRGNQLAMAAGSKTLEIIERERLVERAAIAGRRLRANLERIAAQTPYIGEVRGEGLMLG 391 Query: 395 VEIIDPQAPADVLGNPAAAPALARALQHECLRRGLILELGGRHGCVVRFLPPLVIGEDEL 454 VE++DP+ D LG+P +AR +QHE R G+ILE GGR G V+R LPPLVI + E+ Sbjct: 392 VEVVDPEGLPDALGHPPHGQEIARMIQHEMFRAGIILETGGRFGSVLRLLPPLVISDAEI 451 Query: 455 ERVIDIFAQAL 465 ++V A A Sbjct: 452 DQVSGALAAAF 462 >BH2624 [E] COG0160 4-aminobutyrate aminotransferase and related aminotransferases Bha Bacillus halodurans Length = 454 Score = 498 bits (1282), Expect = e-140, Method: Compositional matrix adjust. Identities = 235/431 (54%), Positives = 313/431 (72%), Gaps = 1/431 (0%) Query: 34 LLQRQARQESNARSYPRRLPLVLKRGAGIYVEDIEGRVFIDCLAGAGTLALGHNHPAVIE 93 L +Q ++ES+ARSYPRRLPL +++ GI V D+ G+ FIDCLAGAGTLALGHNHP + + Sbjct: 14 FLSQQEKRESSARSYPRRLPLAIQKAEGICVTDMNGKQFIDCLAGAGTLALGHNHPVIRQ 73 Query: 94 AIVALLHDGAALHTLDLTTPVKDRFMQDLLEILPPELSRQARVQFCGPTGADAIEAALKL 153 AI +L LH+LDLTTPVK+ F+ ++ LP +++A++ FCGPTGADA+EAA+KL Sbjct: 74 AIEGVLASYVPLHSLDLTTPVKEAFVDEVFASLPESFAKKAKIHFCGPTGADAVEAAVKL 133 Query: 154 VKSATGGGTVLAFQGAYHGMTQGALQLMGSLAPKAPLNGILSGVQFLPYPYDYRCPLGLG 213 VK+ATG +L+FQG YHG T GAL L G+ PK ++ ++ FLPYPY+YRCP G+G Sbjct: 134 VKTATGNRAMLSFQGGYHGSTHGALSLTGTTDPKKRIHALIPDTHFLPYPYEYRCPFGIG 193 Query: 214 GDAGVRAGLHYIAATLNDPEGGVPKPAGVVVEAIQGEGGVIAAPPAWLAGLRQLTQSAEV 273 D G R Y+ + L+DPE G+ KPAG++VE +QGEGG I AP WL LR++T + Sbjct: 194 KD-GHRVNSTYLESLLDDPESGLVKPAGIIVEVVQGEGGSIPAPVEWLKELRRMTSERNI 252 Query: 274 PLILDEVQSGFGRSGKMFAFEHAGITPDVVVLSKAIGGGLPLSVVVYKEQLDQWKPGAHA 333 PLI+DEVQ+G GR+GKMFAFEHAGI PDV+VLSKAIGG LPLSVV+Y +LDQW+PGAH Sbjct: 253 PLIIDEVQTGIGRTGKMFAFEHAGIEPDVLVLSKAIGGSLPLSVVLYDRKLDQWEPGAHI 312 Query: 334 GTFRGNQLAMAAGSATMRVLRSEDLAGQARTKGQRLETALLALRQLHPHIGEVRGRGLML 393 GTFRGNQ+AMA G AT++ ++ + GQ ++ L +++ IG+VRGRGLM+ Sbjct: 313 GTFRGNQMAMATGRATLQYIKENQVPKHVHELGQYVKDQLSSIQSSMRSIGDVRGRGLMI 372 Query: 394 GVEIIDPQAPADVLGNPAAAPALARALQHECLRRGLILELGGRHGCVVRFLPPLVIGEDE 453 GVEIIDP+ + +G+ A LA+A+Q C RGLILE+GGR V+RFLPPL+I ++ Sbjct: 373 GVEIIDPRKQPNAIGSYPAYGELAKAIQRHCFERGLILEVGGRFSSVIRFLPPLIITREQ 432 Query: 454 LERVIDIFAQA 464 L+ V++ F A Sbjct: 433 LDDVLERFYDA 443 >HI0949 [E] COG0160 4-aminobutyrate aminotransferase and related aminotransferases Hin Haemophilus influenzae Length = 454 Score = 459 bits (1182), Expect = e-129, Method: Compositional matrix adjust. Identities = 222/439 (50%), Positives = 302/439 (68%), Gaps = 3/439 (0%) Query: 34 LLQRQARQESNARSYPRRLPLVLKRGAGIYVEDIEGRVFIDCLAGAGTLALGHNHPAVIE 93 L RQ ESN RSYPR+LP + G +V D+EG ++D LAGAGTLALGHNHP +++ Sbjct: 17 FLDRQDVMESNVRSYPRKLPFAYAKAQGCWVTDVEGNEYLDFLAGAGTLALGHNHPILMQ 76 Query: 94 AIVALLHDGAALHTLDLTTPVKDRFMQDLLEILPPELSRQARVQFCGPTGADAIEAALKL 153 AI +L G LHTLDLTTP+KD F ++LL P + + +QF GP+GADA EAA+KL Sbjct: 77 AIKDVLDSGLPLHTLDLTTPLKDAFSEELLSFFPKD---KYILQFTGPSGADANEAAIKL 133 Query: 154 VKSATGGGTVLAFQGAYHGMTQGALQLMGSLAPKAPLNGILSGVQFLPYPYDYRCPLGLG 213 K+ TG G ++AF G +HGMTQGAL L G+L K + ++ GVQF+PYP++YRCP G+G Sbjct: 134 AKTYTGRGNIIAFSGGFHGMTQGALALTGNLGAKNAVENLMPGVQFMPYPHEYRCPFGIG 193 Query: 214 GDAGVRAGLHYIAATLNDPEGGVPKPAGVVVEAIQGEGGVIAAPPAWLAGLRQLTQSAEV 273 G+AG +A Y + D E GV KPA V++EAIQGEGGV++AP ++L +R++TQ + Sbjct: 194 GEAGAKAVEQYFENFIEDVESGVVKPAAVILEAIQGEGGVVSAPISFLQKVREVTQKHGI 253 Query: 274 PLILDEVQSGFGRSGKMFAFEHAGITPDVVVLSKAIGGGLPLSVVVYKEQLDQWKPGAHA 333 +I+DEVQ+GF RSG+MFAFEHAGI PD++V+SKA+GG LPL+V+ +++ D W+P H Sbjct: 254 LMIVDEVQAGFCRSGRMFAFEHAGIEPDIIVMSKAVGGSLPLAVLAIRKEFDAWQPAGHT 313 Query: 334 GTFRGNQLAMAAGSATMRVLRSEDLAGQARTKGQRLETALLALRQLHPHIGEVRGRGLML 393 GTFRGNQLAMA G A+++++R E+LA A+ +G+ L AL L + +P IG VRGRGLM+ Sbjct: 314 GTFRGNQLAMATGYASLKIMRDENLAQNAQERGEYLTNALRELSKEYPCIGNVRGRGLMM 373 Query: 394 GVEIIDPQAPADVLGNPAAAPALARALQHECLRRGLILELGGRHGCVVRFLPPLVIGEDE 453 G++I+D + D G LA A+Q C + L+LE GGR G VVR L + I + E Sbjct: 374 GIDIVDERQSKDATGAYPRDCELAAAIQKACFKNKLLLERGGRGGNVVRVLCAVNINQSE 433 Query: 454 LERVIDIFAQALRVACAAV 472 E I F Q++ A V Sbjct: 434 CEEFIKRFKQSVVDALKVV 452