BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.2220.p (246 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2411 [Q] COG3208 Predicted thioesterase involved in non-riboso... 175 8e-44 PA2425 [Q] COG3208 Predicted thioesterase involved in non-riboso... 150 3e-36 CAC1022 [Q] COG3208 Predicted thioesterase involved in non-ribos... 123 4e-28 alr2045 [Q] COG3208 Predicted thioesterase involved in non-ribos... 121 1e-27 PA2302_4 [Q] COG3208 Predicted thioesterase involved in non-ribo... 108 1e-23 >PA2411 [Q] COG3208 Predicted thioesterase involved in non-ribosomal peptide biosynthesis Pae Pseudomonas aeruginosa Length = 254 Score = 175 bits (444), Expect = 8e-44, Method: Compositional matrix adjust. Identities = 100/236 (42%), Positives = 140/236 (59%), Gaps = 3/236 (1%) Query: 5 PLKLLALPCAGASATMYLRWRRWLPHWVELLPLELPGRGGRIGDAFIEDFEALVLHLGQR 64 P++L LP +GASA Y RWRR LP W+ + P+ELPGRG R+ + D +L L + Sbjct: 5 PVRLFCLPYSGASAMTYSRWRRKLPAWLAVRPVELPGRGARMAEPLQTDLASLAQQLARE 64 Query: 65 -HADCLQGRYVLFGHSMGALLAYGLAQHQQRLGGRVPLGLIVSGSPAPSMR-EPSR-FAD 121 H + QG Y + GHS+GALLA + + LG PLG G+ APS R E R FA+ Sbjct: 65 LHDEVRQGPYAMLGHSLGALLACEVLYALRELGCPTPLGFFACGTAAPSRRAEYDRGFAE 124 Query: 122 KRGDAALMAELRKQGGTPEEVFAHPELLRLTLDTLAADYRVCESFCYRPLPALSLPLQIL 181 + DA L+A+LR GTPEEV + EL+ LTL L AD+ +C S+ ++ P L+ P++ L Sbjct: 125 PKSDAELIADLRDLQGTPEEVLGNRELMSLTLPILRADFLLCGSYRHQRRPPLACPIRTL 184 Query: 182 AGRQDDIAAHRIEAWCKESTLAASLDWFDGGHFFIRAQERAVLATLASALARMAAG 237 GR+D + ++ AW +E+ L+ FDGGHFFI +E VLA + + AG Sbjct: 185 GGREDKASEEQLLAWAEETRSGFELELFDGGHFFIHQREAEVLAVVECQVEAWRAG 240 >PA2425 [Q] COG3208 Predicted thioesterase involved in non-ribosomal peptide biosynthesis Pae Pseudomonas aeruginosa Length = 254 Score = 150 bits (378), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 92/230 (40%), Positives = 126/230 (54%), Gaps = 10/230 (4%) Query: 4 LPLKLLALPCAGASATMYLRWRRWLPHWVELLPLELPGRGGRIGDAFIEDFEALVLHLGQ 63 + L+L LP +GASA ++ RW+ LP W+ LLPLELPGRG R G+A D +LV L Sbjct: 5 VSLQLFCLPYSGASARLFRRWQPSLPGWIRLLPLELPGRGLRFGEALHTDAASLVAQL-- 62 Query: 64 RHADCLQGR------YVLFGHSMGALLAYGLAQHQQRLGGRVPLGLIVSGSPAPSMREPS 117 A LQG Y FGHS+G LLA+ LA +R G PL L +SG P+ + S Sbjct: 63 --AGELQGTLDSASPYAFFGHSLGGLLAFELAHAMRRRGLEGPLALFLSGVSPPAENDVS 120 Query: 118 RFADKRGDAALMAELRKQGGTPEEVFAHPELLRLTLDTLAADYRVCESFCYRPLPALSLP 177 + + DA L+A LR GTPE V P L+++ L + AD+ V S+ Y+ L Sbjct: 121 GYRRAKADAELVAALRDYRGTPEAVLNDPSLMQMLLPVVRADFLVTGSYRYQAHGPLDAA 180 Query: 178 LQILAGRQDDIAAHRIEAWCKESTLAASLDWFDGGHFFIRAQERAVLATL 227 L + GR+D + + + W E+ +LD DG HFFIR Q+ +L L Sbjct: 181 LHLFGGREDSLRSAELLGWLHEAGGDFTLDLLDGQHFFIREQQGQLLRLL 230 >CAC1022 [Q] COG3208 Predicted thioesterase involved in non-ribosomal peptide biosynthesis Cac Clostridium acetobutylicum Length = 253 Score = 123 bits (308), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 72/227 (31%), Positives = 110/227 (48%), Gaps = 1/227 (0%) Query: 6 LKLLALPCAGASATMYLRWRRWLPHWVELLPLELPGRGGRIGDAFIEDFEALVLHLGQRH 65 ++L LP AG A Y W R++P +EL ++LPGR RI D D L+ L + Sbjct: 22 MRLFCLPFAGGGALAYRSWCRYMPPEIELCAVQLPGRENRIKDEKFYDINLLIDELVLQI 81 Query: 66 ADCLQGRYVLFGHSMGALLAYGLAQHQQRLGGRVPLGLIVSGSPAPSMREPSRFADKRGD 125 L + L+GHSMG L+++ LA+ +++ G P L SGS AP + + ++ D Sbjct: 82 LPYLDKPFALYGHSMGGLISFELARRIRKVKGLTPKILFFSGSKAPQLYDHTKDISHLPD 141 Query: 126 AALMAELRKQGGTPEEVFAHPELLRLTLDTLAADYRVCESFCYRPLPALSLPLQILAGRQ 185 + ++ G P+ + EL+ L TL AD+ V E + Y L P+ L G Sbjct: 142 ELFLKAIKSFNGMPDMFWQDRELIEFKLPTLRADFSVLEGYNYYNEEPLECPISALCGEN 201 Query: 186 DDIAAHR-IEAWCKESTLAASLDWFDGGHFFIRAQERAVLATLASAL 231 D I + + +EA ++ L FDG HFFI VL ++ L Sbjct: 202 DKIISKKDMEALALQTKNQFKLRMFDGDHFFINTCRSKVLKSIIEDL 248 >alr2045 [Q] COG3208 Predicted thioesterase involved in non-ribosomal peptide biosynthesis Nos Nostoc sp. PCC 7120 Length = 253 Score = 121 bits (304), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 72/228 (31%), Positives = 115/228 (50%), Gaps = 1/228 (0%) Query: 6 LKLLALPCAGASATMYLRWRRWLPHWVELLPLELPGRGGRIGDAFIEDFEALVLHLGQRH 65 L+L P AG S+ ++ W +LP VE+ +ELPGRG ++ A E LV + Sbjct: 23 LRLFCFPYAGGSSFIFRTWSNYLPASVEVCAIELPGRGRQMQLAPFHKMEPLVDAIASAI 82 Query: 66 ADCLQGRYVLFGHSMGALLAYGLAQHQQRLGGRVPLGLIVSGSPAPSMREPSRFADKRGD 125 L + GHSMG L+++ +A+ + P+ L +SG P + + + Sbjct: 83 YPYLDKPFAFLGHSMGGLVSFEVARFLHKQYDIHPVHLFISGRRPPHIPDLHPPIHNLPE 142 Query: 126 AALMAELRKQGGTPEEVFAHPELLRLTLDTLAADYRVCESFCYRPLPALSLPLQILAGRQ 185 A + ELR GTP V + EL++L L L AD+ V E++ Y P L PL + G Q Sbjct: 143 PAFIEELRHLNGTPSTVLENAELMQLFLPILRADFAVLETYIYTPELPLECPLTVFGGLQ 202 Query: 186 D-DIAAHRIEAWCKESTLAASLDWFDGGHFFIRAQERAVLATLASALA 232 D +++ ++AW +++ +L F G HFF+ + + VL LA L+ Sbjct: 203 DSEVSCDELQAWREQTKADFNLHIFPGDHFFLHSAQSLVLEQLAKYLS 250 >PA2302_4 [Q] COG3208 Predicted thioesterase involved in non-ribosomal peptide biosynthesis Pae Pseudomonas aeruginosa Length = 241 Score = 108 bits (270), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 82/236 (34%), Positives = 118/236 (50%), Gaps = 6/236 (2%) Query: 6 LKLLALPCAGASATMYLRWRRWLPHWVELLPLELPGRGGRIGDAFIEDFEALVLHLGQRH 65 L+L+ALP AG +A + W LP VELL ++ PGR R + F+ D EA++ + Sbjct: 2 LRLIALPPAGGNAGTFRGWDARLPADVELLAIQYPGRQERQDEPFVTDVEAMLCAIDDAL 61 Query: 66 ADCLQGRYVLFGHSMGALLAYGLAQHQQRLGG--RVPLGLIVSGSPAPSMREPSRFADKR 123 L + L G S+G +LAY LA + L G L +I S +P P + P RF Sbjct: 62 LPLLDRPFALIGASLGGMLAYELAARLESLHGLRARQLFVISSRAPGPDLEYP-RF-HAM 119 Query: 124 GDAALMAELRKQGGTPEEVFAHPELLRLTLDTLAADYRVCESFCYRPLPALSLPLQILAG 183 GDA L+ LR+ P EV PEL ++L TL AD R+ + YRP L++P+ + G Sbjct: 120 GDAELLRTLREYDVLPLEVLDDPELREISLATLRADSRLAADYRYRPREPLAIPITAILG 179 Query: 184 RQDD-IAAHRIEAWCKESTLAASLDWFDGGHFFIRAQERAVLATLASALARMAAGG 238 QD ++ I+ W + ++ L+ GGH + V A L LA GG Sbjct: 180 EQDPGVSRVAIDGWRRHAS-RYELETLAGGHGLVVTAAEEVCAILRQRLAPDVPGG 234