BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0001.2204.p         (564 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

RSc1804_1 [QR] COG0500 SAM-dependent methyltransferases Rso Rals...   312   2e-84
RSc1804_2 [Q] COG3208 Predicted thioesterase involved in non-rib...   231   3e-60
CAC1022 [Q] COG3208 Predicted thioesterase involved in non-ribos...   131   5e-30
alr2045 [Q] COG3208 Predicted thioesterase involved in non-ribos...   127   8e-29
PA2425 [Q] COG3208 Predicted thioesterase involved in non-riboso...   114   4e-25

>RSc1804_1 [QR] COG0500 SAM-dependent methyltransferases Rso Ralstonia
           solanacearum
          Length = 337

 Score =  312 bits (799), Expect = 2e-84,   Method: Compositional matrix adjust.
 Identities = 160/317 (50%), Positives = 202/317 (63%), Gaps = 3/317 (0%)

Query: 8   RNRLAYQGLATLLEHAGLADHAHYLNWGYHSDCPDRDQACHRIADHEPNHSQARLVLEII 67
           RNR AY GLA +LE AGLA+HA YLNWGY       D A   +   E    QARLVLE++
Sbjct: 19  RNRSAYAGLADVLERAGLAEHALYLNWGYRPVDGQPDWAARELPPGELGRMQARLVLEVL 78

Query: 68  GKTPLDGKRIMDIGCGRGGALALLQRFYAPTQLIGIDISPSNIAYCRQQHQGRRLRFQLG 127
           G TPLDG+R++D+GCGRGGALAL+ R +AP  L G DIS +NIAYCR++H   RLRFQ+ 
Sbjct: 79  GDTPLDGRRVLDVGCGRGGALALMGRLHAPAALAGADISAANIAYCRKRHTHPRLRFQIA 138

Query: 128 DACRLPHPDNSVDVVLNMESSGAYSDLPAFFEQVQRILAPQGYFCFSDVIDQESLPLLQE 187
           DACRLP+PD+S+DVV N+ESSGAY D+ AFF  V RIL   G FC +DV D +S+  ++ 
Sbjct: 139 DACRLPYPDSSMDVVFNLESSGAYPDIGAFFHHVHRILRVGGRFCLADVFDADSVAWVRA 198

Query: 188 ALSLCGLELQQHRSVRQEVLASRRRASPHLWRRLQQVLAELDNPSLHAELQQYLANPDSP 247
           AL   G  L++ RS+  +V A+R RASP +WRRL   L  LD P L  EL++YLA P S 
Sbjct: 199 ALEQAGFTLERERSIPAQVRAARERASPGIWRRLDTALTALDAPGLRRELERYLAAPSSG 258

Query: 248 LFAALEEGRADYIIQHWRKSTRRAQPIGPALQEALRQRGQRLE---QVQQPRQTQPPTPR 304
           LF ALE+GR DY + HWRK+   A  I   +   L  R  RL+   Q + P    P +P 
Sbjct: 259 LFQALEDGRVDYRLFHWRKTCPAAGRIDADVIARLATRSARLDAALQDRAPSAAAPQSPA 318

Query: 305 PATPAERGGSWLPLSHP 321
           P        +W P + P
Sbjct: 319 PGPANASASAWFPFTAP 335


>RSc1804_2 [Q] COG3208 Predicted thioesterase involved in non-ribosomal
           peptide biosynthesis Rso Ralstonia solanacearum
          Length = 229

 Score =  231 bits (589), Expect = 3e-60,   Method: Compositional matrix adjust.
 Identities = 115/219 (52%), Positives = 147/219 (67%), Gaps = 4/219 (1%)

Query: 331 QLFALPYAGGGASIYRDWT----SASAHWSLHPLQLPGHENRLAEAAHVDMDKLVQQLAA 386
            +FALPYAGGGAS+YR WT      +A W L P+QLPG E+R  E    DM  L  +LA 
Sbjct: 5   NVFALPYAGGGASVYRAWTLPRRPGAAPWQLCPVQLPGRESRFGEPLIDDMATLADRLAD 64

Query: 387 VLQPYAQQPWALLGCSLGGKIAFELARHFSAQGTPPQHLIVLACPAPSVPVRQALSHLPP 446
            + PYA +PWALLGCSLG KIAFE+AR F+ QG PP  L ++ACPAP +P+ + +S    
Sbjct: 65  AIGPYAHRPWALLGCSLGCKIAFEVARRFARQGRPPALLFLMACPAPGLPLGRRISTRAE 124

Query: 447 AQFAHAVAQLGGTPTDILQHTDMMQTVMPALRSDSQLAEHYCCASDCSIDAPITLFYAED 506
           A FA  V  LGGTP ++L   +MM+T+MP LR+DS LAEHY  A D +++ PI +  A D
Sbjct: 125 ADFAREVCHLGGTPPEVLADAEMMRTLMPILRNDSALAEHYVAAEDATVNVPIVMVAAGD 184

Query: 507 DHLVTPEQALQWRNHTRGRFSAQAVAGGHFFLRQQRPQL 545
           DHLVT E+A +W+ H    F  + V GGHFFLRQ+R +L
Sbjct: 185 DHLVTVEEARRWQRHAGAGFDWRLVDGGHFFLRQRRREL 223


>CAC1022 [Q] COG3208 Predicted thioesterase involved in non-ribosomal
           peptide biosynthesis Cac Clostridium acetobutylicum
          Length = 253

 Score =  131 bits (329), Expect = 5e-30,   Method: Compositional matrix adjust.
 Identities = 72/227 (31%), Positives = 117/227 (51%), Gaps = 3/227 (1%)

Query: 331 QLFALPYAGGGASIYRDWTSASA-HWSLHPLQLPGHENRLAEAAHVDMDKLVQQLAAVLQ 389
           +LF LP+AGGGA  YR W         L  +QLPG ENR+ +    D++ L+ +L   + 
Sbjct: 23  RLFCLPFAGGGALAYRSWCRYMPPEIELCAVQLPGRENRIKDEKFYDINLLIDELVLQIL 82

Query: 390 PYAQQPWALLGCSLGGKIAFELARHF-SAQGTPPQHLIVLACPAPSV-PVRQALSHLPPA 447
           PY  +P+AL G S+GG I+FELAR     +G  P+ L      AP +    + +SHLP  
Sbjct: 83  PYLDKPFALYGHSMGGLISFELARRIRKVKGLTPKILFFSGSKAPQLYDHTKDISHLPDE 142

Query: 448 QFAHAVAQLGGTPTDILQHTDMMQTVMPALRSDSQLAEHYCCASDCSIDAPITLFYAEDD 507
            F  A+    G P    Q  ++++  +P LR+D  + E Y   ++  ++ PI+    E+D
Sbjct: 143 LFLKAIKSFNGMPDMFWQDRELIEFKLPTLRADFSVLEGYNYYNEEPLECPISALCGEND 202

Query: 508 HLVTPEQALQWRNHTRGRFSAQAVAGGHFFLRQQRPQLLACIDQLLS 554
            +++ +        T+ +F  +   G HFF+   R ++L  I + L+
Sbjct: 203 KIISKKDMEALALQTKNQFKLRMFDGDHFFINTCRSKVLKSIIEDLN 249


>alr2045 [Q] COG3208 Predicted thioesterase involved in non-ribosomal
           peptide biosynthesis Nos Nostoc sp. PCC 7120
          Length = 253

 Score =  127 bits (319), Expect = 8e-29,   Method: Compositional matrix adjust.
 Identities = 71/227 (31%), Positives = 120/227 (52%), Gaps = 3/227 (1%)

Query: 331 QLFALPYAGGGASIYRDWTS-ASAHWSLHPLQLPGHENRLAEAAHVDMDKLVQQLAAVLQ 389
           +LF  PYAGG + I+R W++   A   +  ++LPG   ++  A    M+ LV  +A+ + 
Sbjct: 24  RLFCFPYAGGSSFIFRTWSNYLPASVEVCAIELPGRGRQMQLAPFHKMEPLVDAIASAIY 83

Query: 390 PYAQQPWALLGCSLGGKIAFELARHFSAQ-GTPPQHLIVLACPAPSVP-VRQALSHLPPA 447
           PY  +P+A LG S+GG ++FE+AR    Q    P HL +     P +P +   + +LP  
Sbjct: 84  PYLDKPFAFLGHSMGGLVSFEVARFLHKQYDIHPVHLFISGRRPPHIPDLHPPIHNLPEP 143

Query: 448 QFAHAVAQLGGTPTDILQHTDMMQTVMPALRSDSQLAEHYCCASDCSIDAPITLFYAEDD 507
            F   +  L GTP+ +L++ ++MQ  +P LR+D  + E Y    +  ++ P+T+F    D
Sbjct: 144 AFIEELRHLNGTPSTVLENAELMQLFLPILRADFAVLETYIYTPELPLECPLTVFGGLQD 203

Query: 508 HLVTPEQALQWRNHTRGRFSAQAVAGGHFFLRQQRPQLLACIDQLLS 554
             V+ ++   WR  T+  F+     G HFFL   +  +L  + + LS
Sbjct: 204 SEVSCDELQAWREQTKADFNLHIFPGDHFFLHSAQSLVLEQLAKYLS 250


>PA2425 [Q] COG3208 Predicted thioesterase involved in non-ribosomal
           peptide biosynthesis Pae Pseudomonas aeruginosa
          Length = 254

 Score =  114 bits (286), Expect = 4e-25,   Method: Compositional matrix adjust.
 Identities = 78/227 (34%), Positives = 112/227 (49%), Gaps = 10/227 (4%)

Query: 330 CQLFALPYAGGGASIYRDWTSASAHW-SLHPLQLPGHENRLAEAAHVDMDKLVQQLAAVL 388
            QLF LPY+G  A ++R W  +   W  L PL+LPG   R  EA H D   LV QLA  L
Sbjct: 7   LQLFCLPYSGASARLFRRWQPSLPGWIRLLPLELPGRGLRFGEALHTDAASLVAQLAGEL 66

Query: 389 QPY--AQQPWALLGCSLGGKIAFELARHFSAQGTPPQHLIVLACPAPSVPVRQALSHL-- 444
           Q    +  P+A  G SLGG +AFELA     +G      + L+  +P  P    +S    
Sbjct: 67  QGTLDSASPYAFFGHSLGGLLAFELAHAMRRRGLEGPLALFLSGVSP--PAENDVSGYRR 124

Query: 445 --PPAQFAHAVAQLGGTPTDILQHTDMMQTVMPALRSDSQLAEHYCCASDCSIDAPITLF 502
               A+   A+    GTP  +L    +MQ ++P +R+D  +   Y   +   +DA + LF
Sbjct: 125 AKADAELVAALRDYRGTPEAVLNDPSLMQMLLPVVRADFLVTGSYRYQAHGPLDAALHLF 184

Query: 503 YAEDDHLVTPEQALQWRNHTRGRFSAQAVAGGHFFLRQQRPQLLACI 549
              +D L + E  L W +   G F+   + G HFF+R+Q+ QLL  +
Sbjct: 185 GGREDSLRSAE-LLGWLHEAGGDFTLDLLDGQHFFIREQQGQLLRLL 230