BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.2193.p (347 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2467 [PT] COG3712 Fe2+-dicitrate sensor, membrane component Pa... 206 8e-53 PA1911 [PT] COG3712 Fe2+-dicitrate sensor, membrane component Pa... 173 6e-43 PA3900 [PT] COG3712 Fe2+-dicitrate sensor, membrane component Pa... 169 9e-42 PA0471 [PT] COG3712 Fe2+-dicitrate sensor, membrane component Pa... 150 3e-36 fecR [PT] COG3712 Fe2+-dicitrate sensor, membrane component Eco ... 142 1e-33 >PA2467 [PT] COG3712 Fe2+-dicitrate sensor, membrane component Pae Pseudomonas aeruginosa Length = 328 Score = 206 bits (523), Expect = 8e-53, Method: Compositional matrix adjust. Identities = 142/334 (42%), Positives = 196/334 (58%), Gaps = 21/334 (6%) Query: 15 DPVLDQAIAWLVKLRADAGRTAPDAVLQARIDAWRLADARHEAVWSELMAAEAQFQ-RLV 73 + V+ QAI WLV+LR+ D LQ AWR HE W ++ A + Q R Sbjct: 10 EAVVRQAIHWLVRLRSQPA----DDRLQRACAAWRAEHGEHERAWQQVSALNEELQGRFK 65 Query: 74 ALPVPPEQWQQPLSELTRTRTRRQARRRWLGGVTLGLGGLALGALAARQAGLWEGLDGQR 133 ALP L + R Q RR+ L ++L + G A+ A R + W+ L Sbjct: 66 ALPGGV-----AYGTLDSSAQRLQ-RRQALKLLSLLVAGGAV-AWVGRDSLPWQRLSAD- 117 Query: 134 YATATGQHRRLALGDGTQLTLDTDTSVQLRFDGRQRLLVLQQGDIFIDTGKDALAAQHRP 193 Y+TATG+ R + L DGT+L L+TD++V +R+D QRL++L +G+IF+ +G D + HRP Sbjct: 118 YSTATGERRSIELVDGTRLQLNTDSAVDVRYDAGQRLILLARGEIFLASGADTQSPTHRP 177 Query: 194 FLVQTAQARLQALGTRFDVRQQQGSTRLTVLEGRV---ATGQEPRT--VIEPGETVDIDA 248 V+TAQ +ALGTRF+VR Q +T L+V EG V A G P V E G++ I A Sbjct: 178 LRVRTAQGLFEALGTRFNVRLQDAATCLSVSEGSVRIDAFGARPLQAPVAEAGQSYRIAA 237 Query: 249 QGHLRRQAAGSAAMDPTAWLEGSLVARQMRLAEVLAEIARYRHGWLQCDAAVAQLRVSGV 308 G R + MD AW +G +V R MRLA+ LAE+ARYR+G+L C A VA LR+SGV Sbjct: 238 DGVRRLE---RPQMDAVAWADGLIVTRDMRLADFLAEVARYRNGYLGCAAEVADLRLSGV 294 Query: 309 FQLQDSDAALESLAQALPVAIERRTRFWVRVVPA 342 ++L D+D L+ LA+ LPV ++R TR+WVRVV A Sbjct: 295 YRLDDTDKLLQVLARTLPVRLQRHTRWWVRVVAA 328 >PA1911 [PT] COG3712 Fe2+-dicitrate sensor, membrane component Pae Pseudomonas aeruginosa Length = 316 Score = 173 bits (438), Expect = 6e-43, Method: Compositional matrix adjust. Identities = 135/329 (41%), Positives = 177/329 (53%), Gaps = 26/329 (7%) Query: 16 PVLDQAIAWLVKLRADAGRTAPDAVLQARIDAWRLADARHEAVWSELMAAEAQFQRLVAL 75 P+LD+A WLV+L+ D+G T D QA WR +H W AE Q L L Sbjct: 12 PILDEAAEWLVRLQ-DSGCT--DDTRQA-CAQWRQRSPQHAHAWER---AERLLQCLGRL 64 Query: 76 PVPPEQWQQPLSELTRTRTRRQARRRWLGGVTLGLGGLALGALAARQAGLWEGLDGQRYA 135 P L+ T R R RRR + + L LGG +LG + L + L QR Sbjct: 65 P-------PALALPTLGRERGLDRRRAIKHLALVLGGASLGLATWQAEPLRDWLADQR-- 115 Query: 136 TATGQHRRLALGDGTQLTLDTDTSVQLRFDGRQRLLVLQQGDIFIDTGKDALAAQHRPFL 195 T G+ RRL L DG+ LTL+TD++V L FD QRL+ L +G+IF+D+ D RPF Sbjct: 116 TGVGEQRRLTLPDGSLLTLNTDSAVDLAFDASQRLVRLLRGEIFVDSRADP-----RPFR 170 Query: 196 VQTAQARLQALGTRFDVRQQQGSTRLTVLEGRVATG--QEPRTVIEPGETVDIDAQGHLR 253 V TA+ARL A RF+VRQ+ +TR+ VL GRV +E GE+V + A G R Sbjct: 171 VATAEARLHAGAARFNVRQEMAATRVAVLAGRVELSPLHGRGRWLESGESVRLGADGEAR 230 Query: 254 RQAAGSAAMDPTAWLEGSLVARQMRLAEVLAEIARYRHGWLQCDAAVAQLRVSGVFQLQD 313 R A P AW G L+A +M LAEVLAE+ARYR G L+CD +A+L VSG + L D Sbjct: 231 RLAFDGL---PDAWTRGMLMADRMPLAEVLAELARYRRGVLRCDPQLARLAVSGAYPLLD 287 Query: 314 SDAALESLAQALPVAIERRTRFWVRVVPA 342 L L P+ + T +W+ +VPA Sbjct: 288 LRRTLGMLQATYPLKVRGVTDYWISLVPA 316 >PA3900 [PT] COG3712 Fe2+-dicitrate sensor, membrane component Pae Pseudomonas aeruginosa Length = 317 Score = 169 bits (428), Expect = 9e-42, Method: Compositional matrix adjust. Identities = 133/340 (39%), Positives = 174/340 (51%), Gaps = 36/340 (10%) Query: 10 PAAAADP--VLDQAIAWLVKLRADAGRTAPDAVLQARIDAWRLADARHEAVWSELMAAEA 67 PAA P V +QA+ WLV+L+ A D L+ WR A HE W + EA Sbjct: 4 PAAPKVPPQVAEQAVRWLVELQGGAD----DERLRQAWQRWRQAAPEHEQAWRHI---EA 56 Query: 68 QFQRLVALPVPPEQWQQPLSELTRTRTRRQARRRWLGGVTLGL--GGLALGALAARQAGL 125 QRL + PL+ RRR L + L L GG A G + Sbjct: 57 VNQRLAGI-------GTPLALAAINAPHSPQRRRALKTLLLVLAAGGSAWGLRESGSLQR 109 Query: 126 WEGLDGQRYATATGQHRRLALGDGTQLTLDTDTSVQLRFDGRQRLLVLQQGDIFIDTGKD 185 W YAT G+ RRLAL DG++L L++DT+V +RFD +R L+L +G+I + TG D Sbjct: 110 WSA----DYATGVGERRRLALADGSRLELNSDTAVDVRFDAGERRLLLLRGEIQLSTGHD 165 Query: 186 ALAAQHRPFLVQTAQARLQALGTRFDVRQQQGSTRLTVLEGRVATGQEPRT----VIEPG 241 RP V +A+ RL+ +GTRFDVRQ G TR+ V EG V E R ++ G Sbjct: 166 P-----RPLHVYSAEGRLRPVGTRFDVRQFAGRTRVAVHEGAVQV--ENRAGQGLLLPSG 218 Query: 242 ETVDIDAQGHLRRQAAGSAAMDPTAWLEGSLVARQMRLAEVLAEIARYRHGWLQCDAAVA 301 +D D + R A + AW +G LVA MRL E LAE+ARYR G L CD + Sbjct: 219 RQLDFDRE---RLGAPQPLPVGSGAWTDGMLVAAGMRLDEFLAEVARYRPGRLGCDPRIG 275 Query: 302 QLRVSGVFQLQDSDAALESLAQALPVAIERRTRFWVRVVP 341 LR+SG + L DS+ L +L LPV + R TR+WV V P Sbjct: 276 GLRISGSYPLDDSERILATLPAVLPVEVRRVTRYWVGVHP 315 >PA0471 [PT] COG3712 Fe2+-dicitrate sensor, membrane component Pae Pseudomonas aeruginosa Length = 323 Score = 150 bits (380), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 120/329 (36%), Positives = 170/329 (51%), Gaps = 24/329 (7%) Query: 17 VLDQAIAWLVKLRADAGRTAPDAVLQARIDAWRLADARHEAVWSELMAAEAQFQRLVALP 76 VLD+AIAW +L D+G PD W A HE W +L + R P Sbjct: 14 VLDEAIAW--QLLLDSGEAHPDD--HRAFHRWYAAHPEHERAWEQLGGLDRHLARAANGP 69 Query: 77 VPPEQWQQPLSELTRTRTRRQARRRWLGGVTLGLG-GLALGALAARQAGLWEGLDGQRYA 135 + L R + R R LGG LGL L +G A + L Y Sbjct: 70 A--------RNALLSGNARFKRRLRRLGGSALGLVLALGVGLGVANRYVPVRYLLADAY- 120 Query: 136 TATGQHRRLALGDGTQLTLDTDTSVQLRFDGRQRLLVLQQGDIFIDTGKDALAAQHRPFL 195 +ATG+ R L L D T + L++ +++ +RFDG +R +VL G+I ++T RPF+ Sbjct: 121 SATGEQRELTLPDATHVRLNSRSAIDVRFDGERRQVVLLAGEILVETAH----GDPRPFV 176 Query: 196 VQTAQARLQALGTRFDVRQQQGSTRLTVLEGRVATGQEPRT---VIEPGETVDIDAQGHL 252 V +A ++ALGTRF VR+++ TRLTVL+ VA E + VI+ G+ V I QG Sbjct: 177 VSSADGDMRALGTRFLVRREEPGTRLTVLQSAVAARAETLSEERVIKEGQQVLILPQG-- 234 Query: 253 RRQAAGSAAMDPTAWLEGSLVARQMRLAEVLAEIARYRHGWLQCDAAVAQLRVSGVFQLQ 312 QA+ +A AW +G LV RLA+++AE+ RY LQ D ++A LRV+G F L+ Sbjct: 235 -LQASEAAPALAGAWAQGMLVVENARLADLVAELGRYSPALLQVDPSIADLRVTGSFPLK 293 Query: 313 DSDAALESLAQALPVAIERRTRFWVRVVP 341 D+ AL++L +LPV R +W VVP Sbjct: 294 DTRLALQALEPSLPVRSVRHNAWWFEVVP 322 >fecR [PT] COG3712 Fe2+-dicitrate sensor, membrane component Eco Escherichia coli K12 Length = 317 Score = 142 bits (358), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 90/225 (40%), Positives = 125/225 (55%), Gaps = 14/225 (6%) Query: 125 LWEGLDGQ----RYATATGQHRRLALGDGTQLTLDTDTSVQLRFDGRQRLLVLQQGDIFI 180 LW+ G+ Y TA G R L DG+ LTL+T ++ +RFD QR + L G+I I Sbjct: 98 LWQSETGEGLRADYRTAKGTVSRQQLEDGSLLTLNTQSAADVRFDAHQRTVRLWYGEIAI 157 Query: 181 DTGKDALAAQHRPFLVQTAQARLQALGTRFDVRQQQGSTRLTV----LEGRVATGQEPRT 236 T KDAL RPF V T Q +L ALGT F VRQQ T+L V +E +A+ + Sbjct: 158 TTAKDAL---QRPFRVLTRQGQLTALGTEFTVRQQDNFTQLDVQQHAVEVLLASAPAQKR 214 Query: 237 VIEPGETVDIDAQGHLRRQAAGSAAMDPTAWLEGSLVARQMRLAEVLAEIARYRHGWLQC 296 ++ GE++ A A + T+W + L L EV+A + RYR+G L+C Sbjct: 215 IVNAGESLQFSASEF---GAVKPLDDESTSWTKDILSFSDKPLGEVIATLTRYRNGVLRC 271 Query: 297 DAAVAQLRVSGVFQLQDSDAALESLAQALPVAIERRTRFWVRVVP 341 D AVA LR+SG F L+++DA L +AQ LPV I+ TR+W+ + P Sbjct: 272 DPAVAGLRLSGTFPLKNTDAILNVIAQTLPVKIQSITRYWINISP 316