BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.2177.p (413 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGc4834 [GEPR] COG0477 Permeases of the major facilitator superf... 124 5e-28 Cgl2686 [GEPR] COG0477 Permeases of the major facilitator superf... 123 6e-28 VC1634 [GEPR] COG0477 Permeases of the major facilitator superfa... 123 6e-28 YPO1267 [GEPR] COG0477 Permeases of the major facilitator superf... 122 2e-27 SA2145 [GEPR] COG0477 Permeases of the major facilitator superfa... 122 2e-27 >AGc4834 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 398 Score = 124 bits (310), Expect = 5e-28, Method: Compositional matrix adjust. Identities = 95/333 (28%), Positives = 162/333 (48%), Gaps = 17/333 (5%) Query: 28 LAIDLYVPALPKMAIDYGTSAQAIQISVTAYLIAYAFGQLVFGPLADAYGRKRVLMLGLG 87 +++ +Y PA+P++ + T+ AI++S++ Y +A QL+ GP +DA+GR+R ++ L Sbjct: 25 ISMAIYTPAMPELTRVFATNESAIKLSLSLYFAGFALAQLLAGPASDAFGRRRASLVFLS 84 Query: 88 LFTLGCVLSLAAPNLETFVAARVLQGFGIAATNLLAKAIITDSFSGQTLIHAYTYMATAW 147 +F G +L++ AP +E + AR++QG G + +A+AI+ D F+G + Sbjct: 85 VFLGGGLLAIFAPTIEVLLLARLIQGIGASVGMTVARAIVRDQFTGAEASSIMNLIGIML 144 Query: 148 GLAPIVAPVIGAHLQEAFGWRSCLVFLLVYSLG----MWVILWRYRETLAQPVHLHPGTL 203 + P + P IG AFGW+S VF L+ LG V+++ T+ + P L Sbjct: 145 AVGPALGPTIGGLSLAAFGWKS--VFFLMAGLGAAAIFSVVIFLRETTVPDKSLIRPRRL 202 Query: 204 FKNARLVLASPVFQSCFLAQGLCYSILLVFNIVGPFMVQNTLQQPPTFFGYLALAIGMM- 262 +L P F L G L + F++ NT+ PT FG IGM+ Sbjct: 203 LSAYGNLLTEPRFLLAALVLGGSIGALYAQATMLTFILINTVGMTPTAFG-----IGMLM 257 Query: 263 ----YFLGGISNRLHHPRLPTAEQRLRIGARVMTLAAFVMLALALGLGLRVWTLIVPVLV 318 YF G I+ R PRL + + +G ++L + ++++ PV V Sbjct: 258 QTGAYFFGSIALRYIAPRLGD-RRSVMLGLCFSGTGGLLILLSVFLIPPSFFSIMGPVAV 316 Query: 319 MAFCAGAMYPTLMAKGNSIFPHIAGLTSAILGF 351 + P+++ + FPHIAG SA++GF Sbjct: 317 ATVGIALLTPSMVTAALAPFPHIAGSASAMMGF 349 >Cgl2686 [GEPR] COG0477 Permeases of the major facilitator superfamily Cgl Corynebacterium glutamicum Length = 398 Score = 123 bits (309), Expect = 6e-28, Method: Compositional matrix adjust. Identities = 109/352 (30%), Positives = 172/352 (48%), Gaps = 17/352 (4%) Query: 31 DLYVPALPKMAIDYGTSAQAIQISVTAYLIAYAFGQLVFGPLADAYGRKRVLMLGLGLFT 90 D+Y+PA+P +A D GT+A +Q+++++++ A GQL+ GPL+D GRK +L+ G Sbjct: 27 DMYLPAMPGIAEDLGTTAPMVQLTLSSFMAGMAIGQLIIGPLSDQLGRKGLLVAGAVAAL 86 Query: 91 LGCVLSLAAPNLETFVAARVLQGFGIAATNLLAKAIITDSFSGQTLIHAYTYMATAWGLA 150 + V+ AP++ V AR++QG G A ++A+AI+ D GQ HA+ + G+A Sbjct: 87 VASVVCALAPSISVLVIARLVQGLGGGACVVIARAIVPDLERGQKAAHAFALLMIIQGIA 146 Query: 151 PIVAPVIGAHLQEAFGWRSCL-VFLLVYSLGMWVILWRYRETLAQPVHLHP----GTLFK 205 P+VAP+IG L FGWR LV + V L + +E+ +PV G + Sbjct: 147 PVVAPLIGGVLVGPFGWRGIFWALALVNFAQLLVALLQIKES--KPVEERTAAGLGGMLS 204 Query: 206 NARLVLASPVFQSCFLAQGLCYSILLVFNIVGPFMVQNTLQQPPTFFGYLALAIGMMYFL 265 N VL +P F + GL + + + PF++QN + P + + + Sbjct: 205 NYVFVLKNPQFLAYVFTLGLSFGAMFSYISASPFVLQNQMGIPVLLYSIIFGVNAFGLIV 264 Query: 266 GGISNRLHHPRLPTAEQRLRIGARVMTLAAFVMLALALGLGLRVWTLIVPVLVMAFCAGA 325 GG+ NR RL RI V LA+F +L L + + I L++ F + Sbjct: 265 GGMVNR----RLLQRIHPHRIMQTV--LASFTVLCALLLIEVLFINWIPLFLLLLFLIVS 318 Query: 326 MYPTLMAK----GNSIFPHIAGLTSAILGFALLLVSSAMMGLAGFVSIHSLT 373 P +MA G + AG SAILGF + + + L G S +LT Sbjct: 319 HIPMVMANATALGTEVVRSRAGSGSAILGFVQFTMGALVSSLVGLGSDKALT 370 >VC1634 [GEPR] COG0477 Permeases of the major facilitator superfamily Vch Vibrio cholerae Length = 401 Score = 123 bits (309), Expect = 6e-28, Method: Compositional matrix adjust. Identities = 83/255 (32%), Positives = 137/255 (53%), Gaps = 7/255 (2%) Query: 6 KHPPNHPRFLLFLICAFASAGQLAIDLYVPALPKMAIDYGTSAQAIQISVTAYLIAYAFG 65 + P L ++ A + LAID+Y+PA+P +A D+G +A A+QI++TAY +A G Sbjct: 9 QQTPQMSLLLYIVLGALGALTPLAIDMYLPAMPTIARDFGVNAGAVQITLTAYTAGFAIG 68 Query: 66 QLVFGPLADAYGRKRVLMLGLGLFTLGCVLSLAAPNLETFVAARVLQGFGIAATNLLAKA 125 QL+ GPLAD++GR+ V++ G+ LF + ++S +E R QGF AA ++ +A Sbjct: 69 QLLHGPLADSFGRRPVMLCGIFLFGIAAMVSATTNGIEALTYIRAAQGFAGAAAAVVIQA 128 Query: 126 IITDSFSGQTLIHAYTYMATAWGLAPIVAPVIGAHLQEAFGWRSCL-VFLLVYSLGMWVI 184 ++ D F + A +++ LAP+VAP+IG HL FGWRS V L +L + ++ Sbjct: 129 VVRDMFDREDFARAMSFVTLVVTLAPLVAPMIGGHLAIWFGWRSIFWVLALFAALVIAMV 188 Query: 185 LWRYRETLA----QPVHLHPGTLFKNARLVLASPVFQSCFLAQGLCYSILLVFNIVGPFM 240 +W+ ETL+ QP+ + +N + +PV + ++ + F G F+ Sbjct: 189 MWKIPETLSPENRQPLRFR--STMRNYFDLCKNPVAMGLIFSGAFSFAGMFAFLTAGAFV 246 Query: 241 VQNTLQQPPTFFGYL 255 + P FGYL Sbjct: 247 YIDIYGVSPDGFGYL 261 >YPO1267 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 399 Score = 122 bits (306), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 100/368 (27%), Positives = 180/368 (48%), Gaps = 23/368 (6%) Query: 28 LAIDLYVPALPKMAIDYGTSAQAIQISVTAYLIAYAFGQLVFGPLADAYGRKRVLMLGLG 87 LAID+Y+P++P +A ++G + +Q++++AY++ +A GQ+ +GP+AD+ GRK V+ G Sbjct: 24 LAIDMYLPSMPIIAQEFGVESGRVQMTLSAYVLGFAIGQMFYGPMADSIGRKPVIFWGTL 83 Query: 88 LFTLGCVLSLAAPNLETFVAARVLQGFGIAATNLLAKAIITDSFSGQTLIHAYTYMATAW 147 +F L + ++E + R L G AA +++ A++ D F+ +++ Sbjct: 84 IFALAGMACALVQSVEQLINMRFLHGLSAAAASVVINALMRDMFTKDEFSRMMSFVVLVM 143 Query: 148 GLAPIVAPVIGAHLQEAFGWRSCLVFLLVYSL-GMWVILWRYRETL----AQPVHLHP-- 200 +AP++AP+IG L F W + + +L G ++ +ETL Q HL Sbjct: 144 TIAPLLAPIIGGALLVWFSWHAIFWTMAGAALVGAVLVALFIQETLPPERRQKFHLRTTI 203 Query: 201 ---GTLFKNARLVLASPVFQSCFLAQGLCYSILLVFNIVGPFMVQNTLQQPPTFFG-YLA 256 G+LF++ R++ S LA G ++ + F GPF+ + P FG Y A Sbjct: 204 GNFGSLFRHKRVL-------SYMLASGFSFAGMFSFLSAGPFVYIDLNGVSPQNFGYYFA 256 Query: 257 LAIGMMYFLGGISNRLHHPRLPTAEQRLRIGARVMTLAAFVMLALALGLGLRVWTLIVPV 316 L I ++ + I++R + R A + R G V + ++ + + GL W L++ V Sbjct: 257 LNIVFLFLMTFINSR--NVRRFGALKMFRFGLIVQFVMGIWLVVVCVA-GLGFWALVLGV 313 Query: 317 LVMAFCAGAMYPTLMAKGNSIFPHIAGLTSAILGFALLLVSSAMMGLAGFVSIHSLTPL- 375 C + MA FPH+AG S++ G + + + L S S P+ Sbjct: 314 AAYVGCIAMITSNAMAVILDDFPHMAGTASSLAGTLRFGIGAVVGTLLSMASSRSAWPMV 373 Query: 376 -AVFFCIV 382 ++ FCI+ Sbjct: 374 SSMAFCII 381 >SA2145 [GEPR] COG0477 Permeases of the major facilitator superfamily Sau Staphylococcus aureus N315 Length = 402 Score = 122 bits (305), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 77/265 (29%), Positives = 135/265 (50%), Gaps = 5/265 (1%) Query: 1 MSTLAKHPPNHPRFLLFLICAFASAGQLAIDLYVPALPKMAIDYGTSAQAIQISVTAYLI 60 M+ L P F++ L + + G L+ID+++P LP + D+ T+ Q++++ ++I Sbjct: 1 MNDLTHFNKRSPIFIIIL-GSLTAIGALSIDMFLPGLPDIRHDFQTTTSNAQLTLSMFMI 59 Query: 61 AYAFGQLVFGPLADAYGRKRVLMLGLGLFTLGCVLSLAAPNLETFVAARVLQGFGIAATN 120 AFG L GP++D+ GR++ L++ + +FTL + + N+ VA R LQG A Sbjct: 60 GLAFGNLFAGPISDSTGRRKPLIIAMIIFTLASLGIVFVHNIWLMVALRFLQGVTGGAAA 119 Query: 121 LLAKAIITDSFSGQTLIHAYTYMATAWGLAPIVAPVIGAHLQEAFGWRSCLVFLLVYSLG 180 ++++AI +D +SG L + G+AP+VAP IG + WR V L ++ Sbjct: 120 VISRAIASDMYSGNELTKFMALLMLVNGIAPVVAPTIGGIILNYSVWRMVFVILTIFGFV 179 Query: 181 MWV-ILWRYRETLAQPVHLHPG---TLFKNARLVLASPVFQSCFLAQGLCYSILLVFNIV 236 M + L + E+L T+FKN +++L +P F L QG+ + IL + Sbjct: 180 MVIGSLLKVPESLTVTNRESSSGLKTMFKNFKILLKTPRFVLPMLIQGMTFVILFTYISA 239 Query: 237 GPFMVQNTLQQPPTFFGYLALAIGM 261 PF++Q F ++ IG+ Sbjct: 240 SPFIIQKIYGMTAIQFSWMFAGIGI 264