BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.2174.p (433 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value STM0689 [GEPR] COG0477 Permeases of the major facilitator superf... 608 e-174 RSc3059 [GEPR] COG0477 Permeases of the major facilitator superf... 572 e-163 RSc3060 [GEPR] COG0477 Permeases of the major facilitator superf... 542 e-154 PA5476 [GEPR] COG0477 Permeases of the major facilitator superfa... 497 e-140 PA4343 [GEPR] COG0477 Permeases of the major facilitator superfa... 276 5e-74 >STM0689 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 434 Score = 608 bits (1569), Expect = e-174, Method: Compositional matrix adjust. Identities = 297/411 (72%), Positives = 346/411 (84%) Query: 8 RGSRAGAVLRVTSGNFLEQFDFFLFGFYATHISKVFFPASSEFASLMLTFAVFGAGFLMR 67 R GA+LRVTSGNFLEQFDFFLFGFYAT+I++ FFPA SEFASLMLTFAVFG+GFLMR Sbjct: 10 RAGTFGAILRVTSGNFLEQFDFFLFGFYATYIARTFFPAESEFASLMLTFAVFGSGFLMR 69 Query: 68 PLGAIILGAYIDEVGRRKGLIVTLSIMASGTILIACVPGYASIGLLAPLLVLAGRLLQGF 127 P+GAI+LGAYID +GRRKGL+VTL+IM GT+LIA VPGY +IGL AP LVL GRLLQGF Sbjct: 70 PVGAIVLGAYIDRIGRRKGLMVTLAIMGCGTLLIALVPGYQTIGLAAPALVLLGRLLQGF 129 Query: 128 SAGAELGGVSVYLAEMATPGRKGFYTAWQSASQQIAIVVAALMGYALNAWLDAAQIAAWG 187 SAG ELGGVSVYL+E+ATPG KGFYT+WQSASQQ+AIVVAAL+GY+LN L I+ WG Sbjct: 130 SAGVELGGVSVYLSEIATPGNKGFYTSWQSASQQVAIVVAALIGYSLNITLGHDAISEWG 189 Query: 188 WRIPFFVGCLIVPFIFLLRRSLQETEAFQARAHRPALGEVYRTMLANWKTVIAGMLLVAM 247 WRIPFF+GC+I+P IF+LRRSLQETEAF R HRP E++ T+ NW+ + AG LLVAM Sbjct: 190 WRIPFFIGCMIIPLIFVLRRSLQETEAFLQRKHRPDTREIFATIAKNWRIITAGTLLVAM 249 Query: 248 TTTTFYLITVYTPTFGRAVLKLSTQASLVVTLLVGLSNFCWLPIGGMVSDRIGRRPVLLA 307 TTTTFY ITVYTPT+GR VL LS + SL+VT+LVG+SNF WLPIGG +SDRIGRR VL+ Sbjct: 250 TTTTFYFITVYTPTYGRTVLNLSARDSLIVTMLVGVSNFIWLPIGGAISDRIGRRAVLMG 309 Query: 308 ITVLAILTAYPALSWLAAAPSVERMLLVLLWLSFFFGMYNGAMVAALTEIMPEQIRVAGF 367 IT+LA++T +P + WL AAP RM LVLLW SFFFGMYNGAMVAALTE+MP +R GF Sbjct: 310 ITLLALITTWPVMQWLTAAPDFTRMTLVLLWFSFFFGMYNGAMVAALTEVMPVYVRTVGF 369 Query: 368 SLAFSLATAVFGGFTPAISTWLIELTGDKAAPGLWLTFAALCGLLATLILY 418 SLAFSLATA+FGG TPAIST L++LTGDK++PG WL AALCGL AT +L+ Sbjct: 370 SLAFSLATAIFGGLTPAISTALVKLTGDKSSPGWWLMCAALCGLAATAMLF 420 >RSc3059 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 431 Score = 572 bits (1473), Expect = e-163, Method: Compositional matrix adjust. Identities = 281/432 (65%), Positives = 339/432 (78%), Gaps = 1/432 (0%) Query: 1 MSTHPHVRGSRAGAVLRVTSGNFLEQFDFFLFGFYATHISKVFFPASSEFASLMLTFAVF 60 M TH + S+A ++ RV SGNFLE +DF ++G+YA I+ FFPA +EF SLML+ F Sbjct: 1 MHTH-NPNESKARSIFRVVSGNFLEMYDFMVYGYYAKAIADTFFPADNEFLSLMLSLVTF 59 Query: 61 GAGFLMRPLGAIILGAYIDEVGRRKGLIVTLSIMASGTILIACVPGYASIGLLAPLLVLA 120 G GFLMRPLGA+ILGAYID GRR GLI+TL +MA GT+LIA VPGYA+IGL APLLVL Sbjct: 60 GVGFLMRPLGALILGAYIDRHGRRAGLILTLGLMACGTLLIALVPGYATIGLAAPLLVLI 119 Query: 121 GRLLQGFSAGAELGGVSVYLAEMATPGRKGFYTAWQSASQQIAIVVAALMGYALNAWLDA 180 GRLLQGFSAG ELGGVSVYLAE++TPGRKGF+ +WQSASQQ+A++ AAL+G L+ L Sbjct: 120 GRLLQGFSAGVELGGVSVYLAEISTPGRKGFFVSWQSASQQVAVMFAALLGVLLSFQLSP 179 Query: 181 AQIAAWGWRIPFFVGCLIVPFIFLLRRSLQETEAFQARAHRPALGEVYRTMLANWKTVIA 240 ++ WGWR+PF VGCLIVPF+FL+RRSLQETE F+ R HRPALGE++R+M NW+ V A Sbjct: 180 KEMGEWGWRVPFLVGCLIVPFLFLIRRSLQETEEFKQRKHRPALGEIFRSMGENWRLVGA 239 Query: 241 GMLLVAMTTTTFYLITVYTPTFGRAVLKLSTQASLVVTLLVGLSNFCWLPIGGMVSDRIG 300 G LLV MTT +FYLIT YTPTFG++VL LS SL+VTL VG SNF WLP+ G VSDRIG Sbjct: 240 GTLLVVMTTVSFYLITAYTPTFGKSVLHLSNLDSLIVTLCVGASNFFWLPVMGSVSDRIG 299 Query: 301 RRPVLLAITVLAILTAYPALSWLAAAPSVERMLLVLLWLSFFFGMYNGAMVAALTEIMPE 360 RRP+L+ T L +LTAYPA+ WL A PS R+L V LWLSF +G YNGAMV LTEIMP Sbjct: 300 RRPLLITFTALTLLTAYPAMQWLIAEPSFGRLLAVELWLSFLYGSYNGAMVVTLTEIMPP 359 Query: 361 QIRVAGFSLAFSLATAVFGGFTPAISTWLIELTGDKAAPGLWLTFAALCGLLATLILYRG 420 +R GFSLA+SLATA+FGGFTPAI+TWLI TG+KA PGLWL+FAA+CGL+ATLI+ + Sbjct: 360 AVRTTGFSLAYSLATAIFGGFTPAIATWLIHATGNKAMPGLWLSFAAICGLVATLIVVKP 419 Query: 421 QAVAMRATASRA 432 + T + A Sbjct: 420 AGRHVHTTVTTA 431 >RSc3060 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 433 Score = 542 bits (1396), Expect = e-154, Method: Compositional matrix adjust. Identities = 268/421 (63%), Positives = 325/421 (77%), Gaps = 1/421 (0%) Query: 1 MSTHPHVRGSRAGAVLRVTSGNFLEQFDFFLFGFYATHISKVFFPASSEFASLMLTFAVF 60 M TH + S+A A+ RV SGNFLE FDF ++G+YAT I+ FFPA + F SLML+ F Sbjct: 1 MHTH-NPNESKARAIFRVVSGNFLEMFDFMVYGYYATAIAATFFPAGNAFLSLMLSLMTF 59 Query: 61 GAGFLMRPLGAIILGAYIDEVGRRKGLIVTLSIMASGTILIACVPGYASIGLLAPLLVLA 120 GAGFLMRPLGAI+LGAYID GRR GLI+TL +MA GT+LIA VPGY +IGL APLLVL Sbjct: 60 GAGFLMRPLGAIVLGAYIDRHGRRAGLILTLVLMACGTMLIALVPGYGTIGLAAPLLVLI 119 Query: 121 GRLLQGFSAGAELGGVSVYLAEMATPGRKGFYTAWQSASQQIAIVVAALMGYALNAWLDA 180 GRLLQGFSAG E GGVSVYL+E+ATPGRKGFY +WQS SQQ+A++ AAL+G L+ L Sbjct: 120 GRLLQGFSAGGEPGGVSVYLSEIATPGRKGFYVSWQSGSQQVAVMFAALLGVLLSFKLSP 179 Query: 181 AQIAAWGWRIPFFVGCLIVPFIFLLRRSLQETEAFQARAHRPALGEVYRTMLANWKTVIA 240 ++ WGWR+PF +GCLIVPF+F +RRSL+ETE F+ R HRP +GE+ R+M NW+ A Sbjct: 180 KEMGEWGWRVPFLIGCLIVPFLFFIRRSLRETEEFEQRKHRPTMGELLRSMGENWRLAGA 239 Query: 241 GMLLVAMTTTTFYLITVYTPTFGRAVLKLSTQASLVVTLLVGLSNFCWLPIGGMVSDRIG 300 G LL MTT +FYLIT YTPTFGR VL +S SL+VTL VG SN WLP+ G +SDRIG Sbjct: 240 GTLLAVMTTVSFYLITAYTPTFGRNVLHMSDFDSLIVTLCVGASNLIWLPVMGSLSDRIG 299 Query: 301 RRPVLLAITVLAILTAYPALSWLAAAPSVERMLLVLLWLSFFFGMYNGAMVAALTEIMPE 360 RR L+ + L +LTAYPA++WL A PS R+L V LWLSF +G YNGAM+ LTEIMP Sbjct: 300 RRTPLIVFSALTLLTAYPAMTWLIAEPSFGRLLAVELWLSFLYGGYNGAMIVTLTEIMPP 359 Query: 361 QIRVAGFSLAFSLATAVFGGFTPAISTWLIELTGDKAAPGLWLTFAALCGLLATLILYRG 420 Q+R GFSLA+SLATA+FGGFTPAI+T LI TG+KA PGLWL+FAA+CGL+ATL + + Sbjct: 360 QLRTTGFSLAYSLATAIFGGFTPAIATGLIHATGNKAMPGLWLSFAAICGLVATLTVVKP 419 Query: 421 Q 421 Q Sbjct: 420 Q 420 >PA5476 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 429 Score = 497 bits (1279), Expect = e-140, Method: Compositional matrix adjust. Identities = 251/393 (63%), Positives = 309/393 (78%) Query: 10 SRAGAVLRVTSGNFLEQFDFFLFGFYATHISKVFFPASSEFASLMLTFAVFGAGFLMRPL 69 S+ A+ RV SGNFLE +DF ++GFYAT I+K FFP + FASLML+ A FGAGFLMRPL Sbjct: 6 SKGVAIFRVVSGNFLEMYDFMVYGFYATAIAKTFFPGDNPFASLMLSLATFGAGFLMRPL 65 Query: 70 GAIILGAYIDEVGRRKGLIVTLSIMASGTILIACVPGYASIGLLAPLLVLAGRLLQGFSA 129 GA+ LGAYID GRR+GLI+TL +MA GT+LIA VPGYA++G+ APLLVL GRLLQGFSA Sbjct: 66 GAVFLGAYIDRHGRRQGLIITLGLMAMGTLLIAFVPGYATLGVAAPLLVLFGRLLQGFSA 125 Query: 130 GAELGGVSVYLAEMATPGRKGFYTAWQSASQQIAIVVAALMGYALNAWLDAAQIAAWGWR 189 G ELGGVSVYL+E+ATPGRKGF+ +WQSASQQ+A+V A L+G LN WL + WGWR Sbjct: 126 GVELGGVSVYLSEIATPGRKGFFVSWQSASQQVAVVFAGLLGVLLNQWLSPQDMGEWGWR 185 Query: 190 IPFFVGCLIVPFIFLLRRSLQETEAFQARAHRPALGEVYRTMLANWKTVIAGMLLVAMTT 249 +PFF+GCLIVP +F++RRSL+ET F+AR HRP+L +V R++ N+ V+AG +V MTT Sbjct: 186 VPFFIGCLIVPALFVIRRSLEETPEFEARTHRPSLSQVLRSIGQNFGVVLAGTAMVVMTT 245 Query: 250 TTFYLITVYTPTFGRAVLKLSTQASLVVTLLVGLSNFCWLPIGGMVSDRIGRRPVLLAIT 309 +FYLIT YTPTFG+ L+LS SL+VT+ +GLSNF WLP+ G SDRIGR+P+LL + Sbjct: 246 VSFYLITAYTPTFGKNELQLSDLDSLLVTMCIGLSNFIWLPVMGAFSDRIGRKPLLLGAS 305 Query: 310 VLAILTAYPALSWLAAAPSVERMLLVLLWLSFFFGMYNGAMVAALTEIMPEQIRVAGFSL 369 LA+LTAYPALSWL PS +L V LWLSF + YNGAMV ALTE+MP +R GFSL Sbjct: 306 ALALLTAYPALSWLVREPSFAGLLGVELWLSFLYSSYNGAMVVALTEVMPADVRTTGFSL 365 Query: 370 AFSLATAVFGGFTPAISTWLIELTGDKAAPGLW 402 A+SLATA FGGFTPA+ TWLI ++AAPG+W Sbjct: 366 AYSLATATFGGFTPAVCTWLIHTLDNRAAPGIW 398 >PA4343 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 439 Score = 276 bits (707), Expect = 5e-74, Method: Compositional matrix adjust. Identities = 163/418 (38%), Positives = 237/418 (56%), Gaps = 1/418 (0%) Query: 10 SRAGAVLRVTSGNFLEQFDFFLFGFYATHISKVFFPASSEFASLMLTFAVFGAGFLMRPL 69 SR V GN LE +DF ++GF ++ I+++FFP+ E+ SL++ A FG GF MRP+ Sbjct: 9 SRTRQVAAAVIGNALEWYDFIVYGFLSSLIARLFFPSGDEYTSLLMALATFGVGFFMRPV 68 Query: 70 GAIILGAYIDEVGRRKGLIVTLSIMASGTILIACVPGYASIGLLAPLLVLAGRLLQGFSA 129 G ++LG Y D GR+ + + + +M +IA P YA+IG+ APLL++ R+LQGF+ Sbjct: 69 GGVLLGLYADRRGRKAAMQLIILLMTLSIAMIAFAPTYAAIGVGAPLLIVIARMLQGFAT 128 Query: 130 GAELGGVSVYLAEMATPGRKGFYTAWQSASQQIAIVVAALMGYALNAWLDAAQIAAWGWR 189 G E + +L E A P R+G Y +WQ Q +A+ A MG + LDA + +WGWR Sbjct: 129 GGEYASATAFLVESAPPHRRGLYGSWQLFGQCLAVFAGAGMGALVTHCLDAEALESWGWR 188 Query: 190 IPFFVGCLIVPFIFLLRRSLQETEAFQARAHRPALGEVYRTMLANW-KTVIAGMLLVAMT 248 +PF G LI P +RR + ETEAF P + +L + ++V+ M L + Sbjct: 189 VPFLFGLLIGPVGLWIRRYMGETEAFLEAIREPGERQGLLGVLREYRRSVLVSMGLTVVG 248 Query: 249 TTTFYLITVYTPTFGRAVLKLSTQASLVVTLLVGLSNFCWLPIGGMVSDRIGRRPVLLAI 308 T +FY++ V PTF L L +V + +P+ G +SDR+GRRPVLL Sbjct: 249 TVSFYVVLVNMPTFAHKQLGLPLDEVFMVQMAAVALMTLVIPLAGGLSDRVGRRPVLLVA 308 Query: 309 TVLAILTAYPALSWLAAAPSVERMLLVLLWLSFFFGMYNGAMVAALTEIMPEQIRVAGFS 368 T+ +L YP +W+AAAPS+ R+LL+ L L G + G A+ E P ++R G + Sbjct: 309 TLAFMLMVYPLFAWVAAAPSLGRLLLMQLLLCTAIGGFFGPAPTAVAEQFPVRVRSTGLA 368 Query: 369 LAFSLATAVFGGFTPAISTWLIELTGDKAAPGLWLTFAALCGLLATLILYRGQAVAMR 426 +A++LA +FGGF P I TWL E+ G AP ++ AA GLLATL L G A R Sbjct: 369 VAYNLAVMLFGGFAPFIVTWLTEVGGSPVAPAFYVLGAAFLGLLATLYLREGATPAPR 426